CN221835919U - Extracellular vesicle separates draws and uses strorage device - Google Patents

Abstract

The utility model discloses a storage device for separating and extracting extracellular vesicles, which comprises a bottom plate and a storage mechanism, wherein the size of a base is matched with the size of the storage mechanism through the combination of the bottom plate, a side plate and a back plate, then a box cover is rotated along a rotating shaft by utilizing a bulge to open a box body, the separated and extracted extracellular vesicles are placed in a sterilized sample tube, a tube cover is screwed, the separated and extracted extracellular vesicles are placed in a groove in the middle of a sponge block, the box cover and the box body are sealed by utilizing a sealing ring, and finally labeling labels are plugged into a labeling groove and are orderly placed on the base, and quick taking is realized through a pull ring.

Description

A storage device for separating and extracting extracellular vesicles

Technical Field

The utility model relates to the technical field of cell storage, in particular to a storage device for separating and extracting extracellular vesicles.

Background Art

Extracellular vesicles refer to vesicle-like bodies with a double-layer membrane structure that fall off the cell membrane or are secreted by cells. Their diameters range from 50nm to 2mm. Extracellular vesicles are widely and stably present in various body fluids and carry various biological molecules of cell origin. They are important tools for cells to transport substances, transduce signals, and realize physiological functions. The storage of extracellular vesicles has high requirements for containers and environment.

The existing storage device for separating and extracting extracellular vesicles has the following problems when in use: First, in a drawer-type cell sample freezing rack with publication number: CN214758842U, although a shock-absorbing mechanism is provided, multiple samples are placed together, and each pull of the drawer will cause shaking of all samples, affecting the integrity of the structure and function of the extracellular vesicles; Second, the existing storage device for separating and extracting extracellular vesicles is deficient in protecting samples. Putting multiple samples in the same drawer is prone to contamination and other conditions, thereby affecting the quality of the samples.

Utility Model Content

The purpose of the utility model is to provide a storage device for separating and extracting extracellular vesicles to solve the problems raised in the above-mentioned background technology.

To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a storage device for separating and extracting extracellular vesicles, comprising a bottom plate and a storage mechanism, side plates are arranged on the left and right sides of the bottom plate, a back plate is connected to the rear side of the bottom plate, a storage mechanism is arranged above the bottom plate, a box body is arranged above the bottom plate, a rotating shaft is installed on the upper rear side of the box body, a box cover is connected above the rotating shaft, a protrusion is arranged on the front side of the box cover, a sealing ring is arranged below the box cover, a pull ring is connected to the upper front side of the box body, a marking groove is arranged below the pull ring, a sponge block is installed inside the box body, a groove is opened in the middle of the sponge block, a sample tube is placed inside the groove, and a tube cover is installed above the sample tube.

Preferably, the box body and the box cover are movably connected via a rotating shaft, and the box body and the box cover are consistent in size.

Preferably, the box body and the pull ring are connected by hot melt, the box body and the pull ring are made of polyethylene material, and the box body and the pull ring correspond one to one.

Preferably, the box cover and the sealing ring are adhesively connected, the sealing ring is made of silicone material, and the box cover and the sealing ring fit tightly.

Preferably, the box body and the sponge block are nested and connected, and the inner diameter of the box body matches the outer diameter of the sponge block.

Preferably, the sponge block and the sample tube are connected by a groove to form a slot, the sample tube is made of glass, and the sponge block fits tightly against the sample tube.

Preferably, the sample tube and the tube cover are threadedly connected, and the outer diameter of the sample tube matches the inner diameter of the tube cover.

Compared with the prior art, the beneficial effects of the utility model are:

1. The utility model makes the size of the base match the size of the storage mechanism through the combination of the bottom plate, the side plate and the back plate, and then uses the protrusion to rotate the box cover along the rotating shaft to open the box body, and the separated and extracted extracellular vesicles are placed in the disinfected sample tube, and the tube cover is tightened, and then placed in the middle groove of the sponge block. The sealing performance is good, which can not only protect the glass sample tube from being easily broken, but also avoid mutual contamination between extracellular vesicles;

2. The utility model seals the box cover and the box body through a sealing ring, and finally inserts the label tag into the label groove, neatly arranges them on the base, and quickly takes them out through a pull ring, while avoiding shaking of other samples, which helps to maintain the integrity of the extracellular vesicles.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG1 is a schematic diagram of the overall right side structure of the present utility model.

FIG. 2 is a schematic diagram of the overall left-side structure of the present invention.

FIG3 is a schematic diagram of a partial structure of the utility model.

FIG. 4 is a schematic diagram of the storage mechanism structure of the present utility model.

In the figure: 1, bottom plate; 2, side plate; 3, back plate; 4, storage mechanism; 401, box body; 402, rotating shaft; 403, box cover; 404, protrusion; 405, sealing ring; 406, pull ring; 407, marking groove; 408, sponge block; 409, groove; 410, sample tube; 411, tube cover.

DETAILED DESCRIPTION

In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

Please refer to Figures 1-4. An embodiment of the utility model is: a storage device for separating and extracting extracellular vesicles, including a bottom plate 1 and a storage mechanism 4, side plates 2 are arranged on the left and right sides of the bottom plate 1, a back plate 3 is connected to the rear side of the bottom plate 1, a storage mechanism 4 is arranged above the bottom plate 1, a box body 401 is arranged above the bottom plate 1, a rotating shaft 402 is installed on the upper rear side of the box body 401, a box cover 403 is connected above the rotating shaft 402, a protrusion 404 is arranged on the front side of the box cover 403, a sealing ring 405 is arranged below the box cover 403, a pull ring 406 is connected to the upper front side of the box body 401, a marking groove 407 is arranged below the pull ring 406, a sponge block 408 is installed inside the box body 401, a groove 409 is opened in the middle of the sponge block 408, a sample tube 410 is placed inside the groove 409, and a tube cover 411 is installed above the sample tube 410.

The box body 401 and the box cover 403 are movably connected via a rotating shaft 402. The box body 401 and the box cover 403 are of the same size, so that each sample tube 410 can be stored independently to avoid mutual contamination between extracellular vesicles, thereby playing a protective role.

The box body 401 and the pull ring 406 are connected by hot melt. The box body 401 and the pull ring 406 are made of polyethylene. The box body 401 and the pull ring 406 correspond one to one. The target box body 401 can be quickly taken out through the pull ring 406 to avoid affecting other box bodies 401.

The box cover 403 and the sealing ring 405 are adhesively connected. The sealing ring 405 is made of silicone. The box cover 403 and the sealing ring 405 fit tightly. The sealing ring 405 made of silicone has good sealing properties, which can prevent water evaporation during the freezing process and help maintain the integrity of the extracellular vesicles.

The box body 401 and the sponge block 408 are nested and connected, and the inner diameter of the box body 401 matches the outer diameter of the sponge block 408. The sponge block 408 can effectively isolate external temperature changes and avoid temperature fluctuations.

The sponge block 408 and the sample tube 410 are connected by a slot through a groove 409. The sample tube 410 is made of glass. The sponge block 408 fits tightly against the sample tube 410, which can protect the sample tube 410 and reduce the shaking of the extracellular vesicles.

The sample tube 410 and the tube cover 411 are threadedly connected. The outer diameter of the sample tube 410 matches the inner diameter of the tube cover 411. The tube cover 411 plays a sealing role to ensure that the extracellular vesicles in the sample tube 410 are not contaminated.

Working principle: First, the base plate 1, the side plate 2 and the back plate 3 are combined to make the size of the base match the size of the storage mechanism 4, and then the box cover 403 is rotated along the rotating shaft 402 by using the protrusion 404 to open the box body 401;

Then, the separated and extracted extracellular vesicles are placed in a sterilized sample tube 410, and the tube cover 411 is tightened, and then placed in the middle groove 409 of the sponge block 408, and the box cover 403 and the box body 401 are sealed with a sealing ring 405;

Finally, the marking tag is inserted into the marking slot 407, neatly placed on the base, and can be quickly taken out through the pull ring 406.

The above is only an embodiment of the utility model, and the common sense such as the known specific structure and characteristics in the scheme is not described too much here. For those skilled in the art, it is obvious that the utility model is not limited to the details of the above exemplary embodiments, and the utility model can be implemented in other specific forms without departing from the spirit or basic features of the utility model. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the utility model is limited by the attached claims rather than the above description, and it is intended to include all changes within the meaning and scope of the equivalent elements of the claims in the utility model. Any figure mark in the claims should not be regarded as limiting the claims involved.

Claims (7)

1. A storage device for separating and extracting extracellular vesicles, comprising a bottom plate (1) and a storage mechanism (4), characterized in that: side plates (2) are arranged on the left and right sides of the bottom plate (1), a back plate (3) is connected to the rear side of the bottom plate (1), a storage mechanism (4) is arranged above the bottom plate (1), a box body (401) is arranged above the bottom plate (1), a rotating shaft (402) is installed on the upper rear side of the box body (401), a box cover (403) is connected above the rotating shaft (402), and the box cover (403) is A protrusion (404) is provided on the front side, a sealing ring (405) is provided below the box cover (403), a pull ring (406) is connected to the upper front side of the box body (401), a marking groove (407) is provided below the pull ring (406), a sponge block (408) is installed inside the box body (401), a groove (409) is provided in the middle of the sponge block (408), a sample tube (410) is placed inside the groove (409), and a tube cover (411) is installed above the sample tube (410). 2. A storage device for separation and extraction of extracellular vesicles according to claim 1, characterized in that the box body (401) and the box cover (403) are movably connected through a rotating shaft (402), and the box body (401) and the box cover (403) are of the same size. 3. A storage device for separation and extraction of extracellular vesicles according to claim 1, characterized in that: the box body (401) and the pull ring (406) are hot-melt connected, the box body (401) and the pull ring (406) are made of polyethylene material, and the box body (401) and the pull ring (406) correspond one to one. 4. A storage device for separation and extraction of extracellular vesicles according to claim 1, characterized in that: the box cover (403) and the sealing ring (405) are adhesively connected, the sealing ring (405) is made of silicone material, and the box cover (403) and the sealing ring (405) are tightly fitted. 5. A storage device for separating and extracting extracellular vesicles according to claim 1, characterized in that the box body (401) and the sponge block (408) are nested and connected, and the inner diameter of the box body (401) matches the outer diameter of the sponge block (408). 6. A storage device for separating and extracting extracellular vesicles according to claim 1, characterized in that: the sponge block (408) and the sample tube (410) are connected by a slot through a groove (409), the sample tube (410) is made of glass, and the sponge block (408) and the sample tube (410) are tightly fitted. 7. A storage device for separating and extracting extracellular vesicles according to claim 1, characterized in that: the sample tube (410) and the tube cover (411) are threadedly connected, and the outer diameter of the sample tube (410) matches the inner diameter of the tube cover (411).