CN221618722U - Filtration device - Google Patents

Abstract

The utility model discloses a suction filtration device. The suction filtration device comprises a suction filtration box and a suction pump. The suction filtration box comprises an upper surface and a plurality of fixing holes are formed on the upper surface, and each fixing hole is used for fixing one solid phase extraction column. The suction pump is connected with the suction filtration box and is configured to provide negative pressure for the plurality of fixing holes so as to suck the reaction solution in the solid phase extraction column. According to the suction filtration device, the reaction solution in the solid-phase extraction column is pumped by the suction pump, and compared with a centrifugal machine, the suction force is larger, so that the pumping flux of the reaction solution is larger, and the pumping speed is higher. In addition, because the suction pump is adopted, the suction filtration box can be horizontally placed, the solid phase extraction column is vertically placed, and can be maintained to be vertical in the suction process, so that the solid phase extraction column after suction filtration meets the test requirement.

Description

Suction filtration device

Technical Field

The utility model relates to the technical field of protein sample pretreatment, in particular to a suction filtration device.

Background

Proteomics is the science of studying the composition and change rule of cellular, tissue or organism proteins by taking proteome as a study object. In the research process of the protein sample, the solid phase extraction column (Solid Phase Extraction, SPE) can be filled with the protein sample and the reaction solution, and after the reaction of the protein sample is finished, the reaction solution needs to be pumped away to fill a new protein sample and the reaction solution.

In the related art, a centrifugal machine is adopted to pump out the reaction solution in the solid phase extraction column, but the centrifugal machine has the problem of small flux, and the solid phase extraction column is inclined by rotation after the centrifugal machine, so that the test requirement is not met.

Disclosure of utility model

The embodiment of the utility model provides a suction filtration device to solve at least one technical problem.

The embodiment of the utility model provides a suction filtration device. The suction filtration device comprises:

The suction filtration box comprises an upper surface, wherein a plurality of fixing holes are formed in the upper surface, and each fixing hole is used for fixing one solid phase extraction column;

And the air pump is connected with the suction box and is configured to provide negative pressure for the plurality of fixing holes so as to suck the reaction solution in the solid-phase extraction column.

According to the suction filtration device, the reaction solution in the solid-phase extraction column is pumped by the suction pump, and compared with a centrifugal machine, the suction force is larger, so that the pumping flux of the reaction solution is larger, and the pumping speed is higher. In addition, because the suction pump is adopted, the suction filtration box can be horizontally placed, the solid phase extraction column is vertically placed, and can be maintained to be vertical in the suction process, so that the solid phase extraction column after suction filtration meets the test requirement.

In certain embodiments, the number of fixation holes is greater than 24.

Therefore, the suction filtration device can suction-filter more than 24 solid-phase extraction columns at a time, and on the other hand, as the centrifugal machine has at most 24 channels, only 24 solid-phase extraction columns can be suction-filtered at a time, compared with the centrifugal machine, the suction filtration device can suction-filter more solid-phase extraction columns at a time, and the efficiency is improved.

In some embodiments, the suction filter box comprises a suction filter tip and is formed with a communication cavity, the suction filter tip is formed with a through hole, the communication cavity is communicated with the plurality of fixing holes and the through hole, and the suction pump is connected with the suction filter tip.

So for fixed orifices, intercommunication chamber and through-hole intercommunication guarantee the normal clear of suction filtration process, simple structure realizes easily.

In certain embodiments, the suction box includes a lower surface opposite the upper surface, from which the suction filter extends downward.

Thus, the suction filter tip is conveniently connected with the air pump so as to provide a normal working environment of the suction filter box.

In some embodiments, the suction filtration device comprises a sealing pad, the sealing pad forms a plurality of second through holes, the sealing pad is arranged on the upper surface, the second through holes are in one-to-one correspondence with the fixing holes, and the solid phase extraction column passes through the second through holes and is then fixed in the fixing holes.

Therefore, the sealing performance of the suction filtration box is improved, and the suction filtration effect of the suction filtration device is ensured.

In certain embodiments, the gasket is made of a silicone material.

Therefore, under the condition of ensuring the sealing performance of the suction filtration box, the stability of the solid phase extraction column can be improved, and the cost is reduced.

In some embodiments, the suction filtration device comprises a clamping frame and a fixing piece, the clamping frame is provided with a through groove, the clamping frame is arranged on the sealing gasket and is detachably fixed on the suction filtration box through the fixing piece, so that the sealing gasket is fixed on the upper surface, and the second through hole is exposed from the through groove.

Thus, through setting up the clamp frame of demountable installation, can change different sealed pads to match different solid-phase extraction posts.

In certain embodiments, the cartridge includes a flange projecting upwardly from an edge of the upper surface, the flange being in dimensional shape and fit with the frame for positioning the frame.

Thus, the positioning is convenient, and the efficiency of the fixed connection of the clamping frame and the suction filtration box is improved.

In certain embodiments, the fastener is a socket head cap screw and the fastener has a dimension M5x30.

Therefore, the suction filter can bear larger load, is convenient to assemble, and can ensure that the suction filter has attractive and smooth appearance.

In some embodiments, the clamping frame, the sealing gasket and the upper surface are formed with a fillet for mating connection, and the radius of the fillet is 2mm.

Therefore, abrasion generated in the assembly process of the suction filtration device is reduced, and the tightness is improved.

Additional aspects and advantages of the utility model will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the utility model.

Drawings

The foregoing and/or additional aspects and advantages of the present utility model will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings, in which:

FIG. 1 is a schematic view of a suction filtration cartridge according to an embodiment of the present utility model;

FIG. 2 is an exploded perspective view of a suction filtration device according to an embodiment of the present utility model;

FIG. 3 is a perspective assembly schematic view of a suction filtration device according to an embodiment of the present utility model;

FIG. 4 is a top view of a suction filtration cartridge according to an embodiment of the present utility model;

FIG. 5 is a front view of a suction box according to an embodiment of the present utility model;

FIG. 6 is a bottom view of a suction box according to an embodiment of the present utility model;

FIG. 7 is a top view of a gasket according to an embodiment of the present utility model;

Fig. 8 is a top view of a clamping frame according to an embodiment of the present utility model.

Reference numerals for main elements:

The solid phase extraction column 20, the suction filtration device 10, the suction filtration box 11, the suction pump 12, the sealing gasket 13, the clamping frame 14, the rounding 15, the upper surface 111, the suction filtration filter 112, the lower surface 113, the flange 114, the second through hole 131, the through groove 141, the fixing hole 1111 and the through hole 1121.

Detailed Description

Embodiments of the present utility model are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary only for explaining the present utility model and are not to be construed as limiting the present utility model.

In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model. In the description of the present utility model, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.

In the description of the present utility model, it should be noted that the terms "mounted," "connected," and "coupled" are to be construed broadly, as well as, for example, fixedly coupled, detachably coupled, or integrally coupled, unless otherwise specifically indicated and defined. It may be a mechanical connection that is made, or may be an electrical connection. Can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the present utility model, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.

The disclosure herein provides many different embodiments or examples for implementing different structures of the utility model. To simplify the present disclosure, components and arrangements of specific examples are described herein. They are, of course, merely examples and are not intended to limit the utility model. Furthermore, the present utility model may repeat reference numerals and/or letters in the various examples, which are for the purpose of brevity and clarity, and which do not themselves indicate the relationship between the various embodiments and/or arrangements discussed. In addition, the present utility model provides examples of various specific processes and materials, but one of ordinary skill in the art will recognize the application of other processes and/or the use of other materials.

Referring to fig. 1 to 3, a suction filtration device 10 is provided in an embodiment of the present utility model. The suction filtration device comprises a suction filtration box 11 and a suction pump 12. The cartridge 11 includes an upper surface 111 and a plurality of fixing holes 1111 are formed in the upper surface 111, each fixing hole 1111 being for fixing one solid phase extraction column 20. The suction pump 12 is connected to the suction box 11 and configured to provide a negative pressure to the plurality of fixing holes 1111 to suck out the reaction solution in the solid phase extraction column 20.

In the above-mentioned suction filtration device 10, the reaction solution in the solid phase extraction column 20 is pumped out by the pump 12, and compared with the centrifuge, the pumping force is larger, so that the pumping flux of the reaction solution is larger and the pumping speed is higher. In addition, due to the adoption of the air pump 12, the suction filtration box 11 can be horizontally placed, so that the solid-phase extraction column 20 is vertically placed, and can be maintained to be vertical in the suction process, so that the solid-phase extraction column 20 after suction filtration meets the test requirement.

Specifically, in one embodiment, as shown in fig. 1 and 2, the suction filtration cartridge 11 includes an upper surface 111, and a plurality of fixing holes 1111 are formed on the upper surface 111, that is, each fixing hole 1111 communicates with the internal space of the suction filtration cartridge 11 and the external environment, so that each solid phase extraction column 20 can be inserted into a corresponding fixing hole 1111 from top to bottom and tightly attached to the edge of the fixing hole 1111 under the action of gravity, thereby improving the tightness of the internal space of the suction filtration cartridge 11 and providing the condition for extracting negative pressure to the suction filtration cartridge 11.

It can be appreciated that the shape and size of the fixing hole 1111 is matched with the shape and size of the contact portion of the solid phase extraction column 20, so that the solid phase extraction column 20 and the fixing hole 1111 can be tightly attached to each other, and the solid phase extraction column 20 can be vertically placed, so that the working stability of the suction filtration device 10 is ensured, and meanwhile, the suction filtration speed can be increased by utilizing the gravity effect, so that the solid phase extraction column 20 after suction filtration meets the test requirement.

In one embodiment, the fixing hole 1111 may be a cylindrical hole or may be a hole with another shape, so as to ensure that the solid phase extraction column 20 is stably placed against the hole, which is not limited herein.

In one embodiment, referring to fig. 3, the air pump 12 may be a vacuum pump, and may be used to pump air in the suction filtration box 11, so that the air pressure in the suction filtration box 11 is lower than the air pressure in the solid phase extraction column 20, and the reaction solution is forced to be pumped out from the solid phase extraction column 20 and flow to the suction filtration box 11, so that the solid phase extraction column 20 is ensured to complete the suction filtration process under the condition of maintaining vertical placement, and further the step of adjusting the inclination angle of the filler for re-suction filtration is saved to meet the test requirement, and the working efficiency is improved.

It will be appreciated that the suction pump 12 is connected to the suction box 11, so that the suction box 11 is continuously pumped with air under the condition that the suction pump 12 is started, and thus a negative pressure environment is formed in the suction box 11, and the reaction solution in the solid phase extraction column 20 is pumped out.

In one embodiment, the suction filtration cartridge 11 may be provided with a container, for example, the container may be a test tube, or may be another container, and may be used to hold the reaction solution extracted from the solid phase extraction column 20, so as to improve the cleanliness of the suction filtration device 10.

In other embodiments, the reaction solution can be discharged from the suction box 11 in real time by providing a slot in the suction box 11, and the reaction solution can be pumped out from the suction box 11 by the air pump 12 to ensure the cleanliness of the suction device 10, which is not particularly limited herein.

In summary, the pumping rate of the pump 12 can be adjusted to provide a larger pumping force, so that the pumping flux of the reaction solution in the solid phase extraction column 20 is larger, that is, the pumping speed of the reaction solution in unit time is faster.

Referring to fig. 4-6, in some embodiments, the number of fastening holes 1111 is greater than 24.

In this way, the suction filtration device 10 can suction-filter more than 24 solid phase extraction columns 20 at a time, and on the other hand, as the centrifuge has at most 24 channels, only 24 solid phase extraction columns 20 can be suction-filtered at a time, so that the suction filtration device 10 can suction-filter more solid phase extraction columns 20 at a time compared with the centrifuge, thereby improving the efficiency.

Specifically, in one embodiment, the number of the fixing holes 1111 is 96, and the fixing holes 1111 are regularly arranged in an array shape of 8 rows and 12 columns on the upper surface 111, so that 96 solid-phase extraction columns 20 can be placed and filtered simultaneously by the suction filtration box 11 at a time, and the suction filtration efficiency is high, and the safety and the stability are good.

It can be appreciated that the number of the fixing holes 1111 is greater than 24, compared with the centrifuge, so that the suction filtration device 10 can suction-filter more solid-phase extraction columns 20 at a time, and meanwhile, the suction filtration process is ensured to be completed under the condition of maintaining the vertical placement of the solid-phase extraction columns 20, so that the suction filtration device is practical and efficient.

Referring to fig. 2 and 3, in some embodiments, the suction box 11 includes a suction filter 112 and is formed with a communication cavity (not shown), the suction filter 112 is formed with a through hole 1121, the communication cavity communicates with a plurality of fixing holes 1111 and the through hole 1121, and the suction pump 12 is connected to the suction filter 112.

Thus, the fixing hole 1111, the communicating cavity and the through hole 1121 are communicated, normal operation of the suction filtration process is guaranteed, and the suction filtration device is simple in structure and easy to realize.

Specifically, in one embodiment, as shown in fig. 2, a communication chamber (not shown) is formed in the suction filtration cartridge 11, and may communicate with the plurality of fixing holes 1111 and the through-holes 1121, so that in the case where the suction pump 12 sucks air through the through-holes 1121, the communication chamber forms a negative pressure such that the reaction solution enters the communication chamber through the fixing holes 1111, thereby achieving the extraction of the reaction solution from the solid phase extraction column 20.

In one embodiment, as shown in fig. 2 and 3, the suction filter 112 may be a silica gel hose, one end of the suction filter 112 may be connected to the through hole 1121 located on the lower surface 113, and the other end may be connected to the suction pump 12, so as to ensure that the suction box 11 discharges air to form a negative pressure environment when the suction pump 12 is started, thereby sucking the reaction solution in the solid phase extraction column 20, and the structure is simple and easy to implement.

In other embodiments, the filter 112 and the through hole 1121 may be disposed at other positions of the filter cartridge 11, for example, the filter 112 and the through hole 1121 are disposed at a side surface (not shown) of the filter cartridge 11, so as to ensure that a negative pressure environment is formed inside the filter cartridge 11, so that the solid phase extraction column 20 can be used for normal suction filtration, which is not limited herein.

In one embodiment, a valve (not shown) may be provided on the suction filter 112, which may be used to control the air extraction rate to meet the actual requirements of the suction filtration process.

For example, in the case that a small amount of reaction solution remains in the solid phase extraction column 20, the extraction force needs to be increased to ensure that the reaction solution is completely extracted, and at this time, the valve may be opened to the maximum to increase the air extraction speed of the extraction cartridge 11, thereby meeting the extraction requirement of the reaction solution.

Referring to fig. 2, in some embodiments, the cartridge 11 includes a lower surface 113 opposite an upper surface 111, and the filter plug 112 extends downwardly from the lower surface 113.

In this way, the suction filter 112 is conveniently connected to the suction pump 12 to provide a normal working environment for the suction box 11.

Specifically, in one embodiment, as shown in fig. 2, the suction filter 112 has a tubular shape, and may be fixedly connected to the through hole 1121 of the lower surface 113, so that the suction filter box 11 forms an air outlet, so as to facilitate the air of the suction filter box 11 to be pumped away and discharged.

In one embodiment, referring to fig. 3, the suction filter 112 extends downward from the lower surface 113, that is, the end of the suction filter 112 away from the through hole 1121 is suspended, so that the suction filter 112 is conveniently connected with the suction pump 12, so as to ensure that the suction box 11 is vacuumized under the condition that the suction pump 12 is started, so that a negative pressure environment is formed in the suction box 11, and further ensure that the suction device 10 works normally.

Referring to fig. 2, 3 and 7, in some embodiments, the suction filtration device 10 includes a sealing pad 13, the sealing pad 13 forms a plurality of second through holes 131, the sealing pad 13 is disposed on the upper surface 111, the plurality of second through holes 131 are in one-to-one correspondence with the plurality of fixing holes 1111, and the solid phase extraction column 20 passes through the second through holes 131 and is fixed in the fixing holes 1111.

In this way, the sealing performance of the suction filtration box 11 is improved, so that the suction filtration effect of the suction filtration device 10 is ensured.

Specifically, in one embodiment, as shown in fig. 7, the sealing pad 13 forms a plurality of second through holes 131, where the number of the second through holes 131 is 96, and the second through holes 131 are regularly arranged in an array shape of 8 rows and 12 columns on the sealing pad 13, so that 96 solid-phase extraction columns 20 can be clamped at a time, and the suction filtration effect is improved under the condition of ensuring the sealing performance of the suction filtration box 11.

In one embodiment, as shown in fig. 2 and 3, the sealing gasket 13 is disposed on the upper surface 111, and the plurality of second through holes 131 are in one-to-one correspondence with the plurality of fixing holes 1111, so that the solid phase extraction column 20 can be placed in a penetrating manner along the direction from the second through holes 131 to the fixing holes 1111, thereby ensuring that the solid phase extraction column 20 is vertically placed in the suction filtration box 11 and is limited and fixed through the fixing holes 1111, and further avoiding the solid phase extraction column 20 from shaking in the horizontal direction.

In one embodiment, the gasket 13 may be made of an elastic material to ensure that contact wear between the gasket 13 and the solid phase extraction column 20 is reduced, while ensuring a sealing effect.

In one embodiment, the aperture of the fixing hole 1111 is matched with the diameter of the solid phase extraction column 20, and the aperture of the second through hole 131 is smaller than the diameter of the solid phase extraction column 20, so that the sealing gasket 13 plays a role in clamping, fixing and sealing when the solid phase extraction column 20 passes through the second through hole 131, thereby ensuring the safety and the suction filtration effect of the suction filtration device 10.

For example, in one example, the diameter of the second through hole 131 is 1mm, the diameters of the fixing holes 1111 and the solid phase extraction column 20 are 3.5mm, and when the solid phase extraction column 20 passes through the second through hole 131 and is fixed in the fixing hole 1111, the sealing gasket 13 is tightly sealed with the solid phase extraction column 20 through the second through hole 131, that is, the solid phase extraction column 20 is inflated by the elasticity of the sealing gasket 13 and penetrates through the second through hole 131, so that the solid phase extraction column 20 is clamped in the second through hole 131 and is stably and vertically placed, thereby ensuring that the suction filtration device 10 works normally.

In some embodiments, the gasket 13 is made of a silicone material.

Thus, the stability of the solid phase extraction column 20 can be improved and the cost can be reduced while the sealing performance of the suction filtration box 11 is ensured.

Specifically, in one embodiment, as shown in FIGS. 2 and 7, the gasket 13 should be shaped to match the shape of the upper surface 111, while a soft material may be used to reduce wear of the gasket 13 and the solid phase extraction cartridge 20 during assembly.

In one embodiment, the sealing pad 13 is made of a silica gel material, and the size of the second through hole 131 is smaller than the diameter of the solid phase extraction column 20, so that the solid phase extraction column 20 is ensured not to wear when passing through the sealing pad 13, that is, the solid phase extraction column 20 can swell the second through hole 131 by using elasticity of silica gel, so as to pass through and be clamped in the second through hole 131, and the sealing performance and the stability are good.

In one embodiment, the sealing gasket 13 is made of a silica gel material, so that the sealing performance of the suction filtration device 10 is good, the stability of the solid phase extraction column 20 is ensured, the production cost is reduced, and the practicability is good.

Referring to fig. 2, 3 and 8, in some embodiments, the suction filtration device 10 includes a clamping frame 14 and a fixing member (not shown), the clamping frame 14 is formed with a through slot 141, and the clamping frame 14 is disposed on the gasket 13 and is detachably fixed to the suction filtration box 11 by the fixing member, so that the gasket 13 is fixed to the upper surface 111, and the second through hole 131 is exposed from the through slot 141.

Thus, by providing a removably mounted clamping frame 14, different gaskets 13 can be replaced to match different solid phase extraction cartridges 20.

Specifically, in one embodiment, as shown in fig. 2 and fig. 8, the clamping frame 14 is a quadrangular frame with a hollowed-out middle, and a plurality of first slots (not shown) are formed in a circumferential edge of the clamping frame 14, wherein, as shown in fig. 2 and fig. 4, a plurality of second slots (not shown) are formed in a circumferential edge of the upper surface 111 of the suction filtration box 11, and the clamping frame 14 and the upper surface 111 of the suction filtration box 11 can be fixedly connected by penetrating the first slots and the second slots through fixing pieces (not shown), so that the sealing gasket 13 is stably clamped between the clamping frame 14 and the suction filtration box 11.

In detail, referring to fig. 2 and 7, a plurality of third slots (not shown) are provided at the circumferential edge of the sealing pad 13, and the plurality of third slots are in one-to-one correspondence with the plurality of first slots and the plurality of second slots, so that the fixing member can sequentially pass through the first slots, the third slots and the second slots to be fixedly connected, thereby ensuring that the clamping frame 14, the sealing pad 13 and the suction filtration box 11 are stably connected, and further ensuring that the suction filtration device 10 works stably.

It will be appreciated that, as shown in fig. 2 and 8, the clamping frame 14 is formed with a through slot 141, so that the second through holes 131 of the sealing pad 13 are exposed from the through slot 141 under the condition that the clamping frame 14, the sealing pad 13 and the suction filtration box 11 are stably connected, so as to ensure that the plurality of solid phase extraction columns 20 respectively pass through the second through holes 131 to at least partially suction filtration box 11, thereby ensuring that the suction filtration device 10 works normally.

In one embodiment, the clamping frame 14 is detachably fixed on the suction filtration box 11 through a fixing piece, so that the requirement of a user for replacing the sealing gasket 13 can be met, the sealing gasket 13 is matched with the solid-phase extraction column 20 in size, and the suction filtration effect of the suction filtration device 10 is ensured.

Referring to fig. 1-3, in some embodiments, the cartridge 11 includes a flange 114, the flange 114 protruding upward from the edge of the upper surface 111, the flange 114 being sized to mate with the shape of the frame 14 for positioning the frame 14.

Thus, the positioning is convenient, and the efficiency of the fixed connection of the clamping frame 14 and the suction filtration box 11 is improved.

Specifically, in one embodiment, as shown in fig. 1 and 2, the flange 114 may enclose a square groove (not shown) on the upper surface 111 of the suction filtration cartridge 11, so that the gasket 13 is stably filled in the square groove, thereby ensuring the sealing performance of the suction filtration device 10.

In one embodiment, as shown in fig. 2 and 3, the flange 114 is in a form-fit with the frame 14, i.e., the outer side of the frame 14 may form a clearance fit with the inner side of the flange 114, such that the frame 14 is disposed on the gasket 13 and at least partially clamped within the square groove, thereby ensuring stability of the suction filtration device 10.

It will be appreciated that the flange 114 protrudes upward from the edge of the upper surface 111, so that the clamping frame 14 can be positioned and installed quickly, thereby improving the efficiency of the fixed connection between the clamping frame 14 and the suction filtration box 11, and further improving the assembly efficiency of the suction filtration device 10.

In some embodiments, the fastener is a socket head cap screw, and the fastener has a dimension M5x30.

Thus, the suction filter device 10 can bear larger load, is convenient to assemble, and can ensure attractive and smooth appearance.

In particular, in one embodiment, the fixing element may be composed of two parts, a head and a screw (a cylinder with external threads), which may be coupled with a nut for fastening at least two parts with through holes.

In one embodiment, the fixing piece is an inner hexagon screw, so that the stress surfaces of the fixing piece are 6, the contact area and the mechanical strength are increased, and the fixing piece is easy to fix or detach and convenient to assemble.

In one embodiment, the fixing member is an inner hexagon screw, and can be buried and fixed inside the workpiece to conceal the workpiece, so that the flatness of the surface of the workpiece is improved. For example, the fixing member may pass through the clamping frame 14 and enable the nut to be located inside the first slot hole in the circumferential direction of the clamping frame 14, so that the appearance of the suction filtration device 10 is attractive under the condition that the connection stability of the suction filtration device 10 is ensured.

In one embodiment, the fixing member may have a diameter of 5mm and a length of 30mm, so as to ensure that the clamping frame 14, the sealing gasket 13 and the suction filtration box 11 are stably connected, thereby ensuring that the suction filtration device 10 works normally.

For example, in one example, the diameter of the first slot (not shown) on the clamping frame 14 may be 5mm, the diameter of the second slot (not shown) on the sealing pad 13 may be 4.2mm and have elasticity, and the diameter of the third slot (not shown) on the upper surface 111 may be 5mm, so that the fixing member having the diameter of 5mm may be ensured to be penetrated and stably fixed in the first slot, the second slot and the third slot, thereby ensuring that the clamping frame 14, the sealing pad 13 and the suction filtration cartridge 11 are stably connected.

In addition, in one example, the thickness dimension of the clamping frame 14 may be 5mm, the thickness dimension of the sealing pad 13 may be 2.5mm, so as to ensure that the fixing piece with the length of 30mm passes through the clamping frame 14 and the sealing pad 13 and is fixedly connected in the suction filtration box 11, that is, the suction filtration box 11 with the thickness dimension greater than or equal to 22.5mm may be arranged to ensure that the fastening piece is stably connected and is hidden, so that the remaining length of the fixing piece after passing through the clamping frame 14 and the sealing pad 13 is compensated, and further, the stable connection of the suction filtration device 10 is ensured.

Referring to fig. 2 and 3, in some embodiments, the clamping frame 14, the sealing gasket 13 and the upper surface 111 are formed with a fillet 15 for mating connection, and the radius of the fillet 15 is 2mm.

In this way, wear of the suction filtration device 10 during assembly is reduced, thereby improving the sealing performance.

Specifically, in one embodiment, as shown in fig. 2 and 3, the flange 114 of the suction filtration box 11 is circumferentially formed with a rounded corner 15 with a radius of 2mm, and the outer edges of the clamping frame 14 and the sealing gasket 13 are both formed with a rounded corner 15 with a radius of 2mm, so that the clamping frame 14 and the sealing gasket 13 are respectively matched and pressed on the upper surface 111, thereby the suction filtration device 10 is tightly connected and has good sealing performance.

It can be understood that the clamping frame 14, the sealing gasket 13 and the flange 114 are all formed with rounded corners 15 with the radius of 2mm, so that abrasion generated in the process of respectively crimping and installing the clamping frame 14 and the sealing gasket 13 on the upper surface 111 can be reduced, that is, the rounded corners 15 are arranged in a smooth curve, the clamping frame 14 and the sealing gasket 13 are convenient to install, and meanwhile, the sealing arrangement of the suction filtration device 10 is ensured, and the safety is good.

In the description of the present specification, reference to the terms "one embodiment," "some embodiments," "illustrative embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

While embodiments of the present utility model have been shown and described, it will be understood by those of ordinary skill in the art that: many changes, modifications, substitutions and variations may be made to the embodiments without departing from the spirit and principles of the utility model, the scope of which is defined by the claims and their equivalents.

Claims (10)

1. A suction filtration device, comprising:

The suction filtration box comprises an upper surface, wherein a plurality of fixing holes are formed in the upper surface, and each fixing hole is used for fixing one solid phase extraction column;

And the air pump is connected with the suction box and is configured to provide negative pressure for the plurality of fixing holes so as to suck the reaction solution in the solid-phase extraction column.

2. The suction filtration device of claim 1, wherein the number of fixation holes is greater than 24.

3. The suction filtration device according to claim 1, wherein the suction filtration cartridge includes a suction filtration filter and is formed with a communication chamber, the suction filtration filter is formed with a through hole, the communication chamber communicates the plurality of fixing holes and the through hole, and the suction pump is connected with the suction filtration filter.

4. A suction filter arrangement according to claim 3, wherein the suction box comprises a lower surface opposite the upper surface, the suction filter extending downwardly from the lower surface.

5. The suction filtration device according to claim 1, wherein the suction filtration device comprises a sealing gasket, the sealing gasket forms a plurality of second through holes, the sealing gasket is arranged on the upper surface, the plurality of second through holes are in one-to-one correspondence with the plurality of fixing holes, and the solid phase extraction column passes through the second through holes and is then fixed in the fixing holes.

6. The suction filtration device of claim 5, wherein the gasket is made of a silicone material.

7. The suction filtration device according to claim 5, wherein the suction filtration device comprises a clip frame and a fixing member, the clip frame is formed with a through groove, the clip frame is provided on the gasket and detachably fixed on the suction filtration box by the fixing member, thereby fixing the gasket on the upper surface, and the second through hole is exposed from the through groove.

8. The suction filtration device of claim 7, wherein the suction filtration cartridge comprises a flange projecting upwardly from an edge of the upper surface, the flange being in dimensional shape engagement with the clamping frame for positioning the clamping frame.

9. The suction filtration device of claim 7, wherein the fixing member is a socket head cap screw, and the fixing member has a size of M5x30.

10. The suction filtration device according to claim 7, wherein the clamping frame, the sealing gasket and the upper surface are formed with a fillet for mating connection, the radius of the fillet being 2mm.