CN221326029U - Protein quantitative sampling device for mass spectrum detection - Google Patents
Protein quantitative sampling device for mass spectrum detection Download PDFInfo
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- CN221326029U CN221326029U CN202323280019.XU CN202323280019U CN221326029U CN 221326029 U CN221326029 U CN 221326029U CN 202323280019 U CN202323280019 U CN 202323280019U CN 221326029 U CN221326029 U CN 221326029U
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- 238000005070 sampling Methods 0.000 title claims abstract description 111
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 42
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 42
- 238000001819 mass spectrum Methods 0.000 title claims abstract description 14
- 238000001514 detection method Methods 0.000 title claims abstract description 13
- 238000007789 sealing Methods 0.000 claims abstract description 16
- 238000004949 mass spectrometry Methods 0.000 claims description 7
- 238000005299 abrasion Methods 0.000 abstract description 3
- 230000002035 prolonged effect Effects 0.000 abstract description 3
- 238000004140 cleaning Methods 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 230000009471 action Effects 0.000 description 9
- 230000005540 biological transmission Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 4
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 3
- 235000017491 Bambusa tulda Nutrition 0.000 description 3
- 241001330002 Bambuseae Species 0.000 description 3
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 3
- 239000011425 bamboo Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
The utility model belongs to the field of protein quantitative sampling equipment, in particular to a protein quantitative sampling device for mass spectrum detection, which aims at solving the problems that the existing protein quantitative sampling device for mass spectrum detection needs to be provided with threads in a sampling tube, not only the tightness between the sampling tube and a rubber column is affected, but also raw materials are stored in a thread groove and are inconvenient to clean. According to the quantitative sampling device, quantitative sampling of proteins in two forms can be realized through matching of all the components, so that the tightness of the sampling tube is improved, the cleaning of the interior of the sampling tube is facilitated, the purpose of reducing the abrasion of the sealing plate is achieved, and the service life is prolonged.
Description
Technical Field
The utility model relates to the technical field of protein quantitative sampling equipment, in particular to a protein quantitative sampling device for mass spectrum detection.
Background
The mass spectrum detection is an analysis method of ion charge-mass ratio, can be used for analyzing isotope components, organic matter structures, element components and the like, the quantitative protein sampling refers to sampling and then detecting the protein content by a physical or chemical method, the protein is an important component constituting human cells and tissues, and the protein determination is one of the most common and basic analysis methods in biochemical and molecular biological research;
There is certain drawback among the prior art, firstly, quantitative sampling's effect is not good enough, can not carry out liquid protein's addition or decrement according to actual conditions, and secondly, is not good enough to sampling equipment's fixed effect, and the result of use is relatively poor, is to above-mentioned problem application number: 202020921529.8 discloses a protein quantitative sampling device for mass spectrum detection, which comprises a device main body, wherein the lower end of the device main body is provided with a base, the center of the outer surface of the upper end of the base is provided with a fixed support, the outer surface of the fixed support, which is close to the edge of the lower end, is provided with a weight block, the outer surface of the upper end of the fixed support is provided with a top plate, the outer surface of the lower end of the top plate is provided with a convex magnetic column, the outer surface of the lower end of the convex magnetic column is provided with a concave magnetic column, the outer surface of the lower end of the concave magnetic column is provided with a threaded column, the outer surface of the threaded column is provided with a sampling tube, the outer surface of the sampling tube is provided with scales, and the outer surface of the lower end of the sampling tube is provided with a sampling head;
However, the existing quantitative protein sampling device for mass spectrum detection needs to be provided with threads in a sampling tube, so that the tightness between the sampling tube and a rubber column is affected, raw materials are stored in a thread groove and are inconvenient to clean, two ends of a connecting column are fixedly connected with the thread column and the rubber column respectively, the rubber column can synchronously rotate along with the thread column, the abrasion of the rubber column is further increased, and the service life of equipment is prolonged.
Disclosure of utility model
The utility model aims to solve the defects in the prior art, and provides a protein quantitative sampling device for mass spectrum detection.
In order to achieve the above purpose, the present utility model adopts the following technical scheme:
The utility model provides a mass spectrum detects and uses protein ration sampling device, includes base, sampling tube and pinion rack, the top fixedly connected with plane bearing of sampling tube, the top fixedly connected with pinion rack of plane bearing, threaded connection has the threaded rod on the pinion rack, the one end fixedly connected with connecting rod of threaded rod, the one end rotation of connecting rod is connected with the closing plate, the closing plate with the sampling tube contact connection, the other end fixedly connected with concave magnetic path of threaded rod, concave magnetic path with the pinion rack contact connection, be equipped with the telescopic link on the base, the top of telescopic link is equipped with the roof, the bottom fixed mounting of roof has protruding magnetic path, protruding magnetic path with concave magnetic path jogged connection, at first aim at protein with the one end of sampling head, then rotate the pinion rack, owing to protruding magnetic path with concave magnetic path jogged, thereby make the threaded rod keep fixed, simultaneously the buckle ring with the sampling tube lock makes the sampling tube keep fixed, thereby make in the rotation in the pinion rack, the pinion rack with the annular path of thread bar, the bottom fixed mounting has protruding magnetic path, then moves the top plate through the bottom fixed mounting of thread of threaded rod, then moves upwards through the screw rod and makes the top plate parallel to the sample tube simultaneously, then moves upwards through the measuring rod.
Specifically, one side fixedly connected with dead lever of telescopic link, the one end fixedly connected with buckle ring of dead lever, buckle ring with the sample section of thick bamboo contact is connected, is used for right the fixing of sample section of thick bamboo, protruding magnetic path with concave magnetic path attracts each other, is convenient for take off or install the sample section of thick bamboo.
Specifically, the one end of sampling tube is equipped with the sampling head, is convenient for sample to the protein.
Specifically, be equipped with the scale on the sampling tube, be convenient for quantitative sample.
Specifically, the inside diameter of annular plate is less than the inside diameter of sampling tube prevents the threaded rod with the contact of sampling tube, and then prevents its wearing and tearing to the sampling tube inner wall.
Specifically, the internal diameter of plane bearing is the same with the internal diameter of sampling tube and inner wall parallel and level, for detachable connection.
Specifically, fixed cover is equipped with the baffle on the connecting rod, the baffle with the closing plate rotates to be connected, through the effect of baffle makes the threaded rod drives the connecting rod pivoted is simultaneously and drive the closing plate removes, thereby reaches prevent the closing plate is along with threaded rod pivoted purpose.
Compared with the prior art, the utility model has the beneficial effects that:
(1) According to the protein quantitative sampling device for mass spectrum detection, one end of a sampling head is aligned with protein, then the annular plate is rotated, the convex magnetic block is embedded with the concave magnetic block, so that the threaded rod is kept fixed, meanwhile, the clamping ring is buckled with the sampling tube, so that the sampling tube is kept fixed, in the process of rotating the annular plate, the annular plate and the threaded rod are in threaded transmission, so that the threaded rod moves upwards in parallel, the telescopic rod extends upwards through the transmission of the top plate, the threaded rod drives the sealing plate to move upwards in parallel through the action of the connecting rod and the blocking plate, meanwhile, the protein enters the sampling tube through the sampling head through the action of atmospheric pressure, and then the purpose of quantitatively sampling the protein is achieved according to the scale on the observation sampling tube.
(2) According to the protein quantitative sampling device for mass spectrum detection, the sampling tube can be removed from the convex magnetic block and the clamping ring, so that the sampling tube is separated from the clamping ring, meanwhile, the convex magnetic block is separated from the concave magnetic block, then, a user holds the sampling tube and the ring plate by hand to enable the ring plate to be fixed, then, the concave magnetic block is rotated, the concave magnetic block drives the threaded rod to rotate and drive the threaded rod to rotate with the ring plate, meanwhile, the threaded rod drives the connecting rod to rotate under the action of the baffle plate and drives the sealing plate to move, and therefore the purpose of preventing the sealing plate from rotating along with the threaded rod is achieved, and protein sampling is achieved.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It should be understood that the drawings described below are merely exemplary, and that the structures, proportions, sizes, etc. shown in the present specification are merely illustrative of the contents of the present specification, for the understanding and appreciation of the skilled artisan, and are not meant to limit the limitations upon the practice of the present utility model, so that there is no technical significance to any modification, change in the proportions, or adjustment of the size of the structures.
FIG. 1 is a schematic diagram showing the front view structure of a quantitative protein sampling device for mass spectrometry according to the present utility model;
FIG. 2 is an enlarged schematic view of the structure shown at A in FIG. 1;
Fig. 3 is a schematic view of the structure of the threaded rod, the annular plate, the sampling tube, the sampling head, the scale and the bayonet ring.
In the figure: 1. a base; 2. a telescopic rod; 3. a top plate; 4. a convex magnetic block; 5. a concave magnetic block; 6. a threaded rod; 7. a ring plate; 8. a planar bearing; 9. a sampling tube; 10. a connecting rod; 11. a sealing plate; 12. a resistance plate; 13. a sampling head; 14. a scale; 15. a fixed rod; 16. a snap ring.
Detailed Description
Other advantages and advantages of the present utility model will become apparent to those skilled in the art from the following detailed description, which, by way of illustration, is to be read in connection with certain specific embodiments, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-3, a protein quantitative sampling device for mass spectrum detection comprises a base 1, a sampling tube 9 and a ring plate 7, wherein a plane bearing 8 is fixedly connected to the top of the sampling tube 9, the ring plate 7 is fixedly connected to the top of the plane bearing 8, a threaded rod 6 is connected to the ring plate 7 in a threaded manner, a connecting rod 10 is fixedly connected to one end of the threaded rod 6, a sealing plate 11 is connected to one end of the connecting rod 10 in a rotating manner, the sealing plate 11 is connected with the sampling tube 9 in a contact manner, a concave magnetic block 5 is fixedly connected to the other end of the threaded rod 6, the concave magnetic block 5 is connected with the ring plate 7 in a contact manner, a telescopic rod 2 is arranged on the base 1, a top plate 3 is arranged at the top of the telescopic rod 2, a convex magnetic block 4 is fixedly arranged at the bottom of the top plate 3, the convex magnetic block 4 is connected with the concave magnetic block 5 in a jogged manner, firstly, one end of a sampling head 13 is aligned with protein, then the ring plate 7 is rotated, as the convex magnetic block 4 is embedded with the concave magnetic block 5, the threaded rod 6 is kept fixed, meanwhile, the buckling ring 16 is buckled with the sampling tube 9, so that the sampling tube 9 is kept fixed, thus, in the process of rotating the ring plate 7, the ring plate 7 and the threaded rod 6 are in threaded transmission, the threaded rod 6 moves upwards in parallel, meanwhile, the telescopic rod 2 extends upwards through the transmission of the top plate 3, meanwhile, the threaded rod 6 drives the sealing plate 11 to move upwards in parallel through the action of the connecting rod 10 and the baffle plate 12, meanwhile, the protein enters the sampling tube 9 through the sampling head 13 through the action of atmospheric pressure, then according to the scale 14 on the observation sampling tube 9, thereby achieving the purpose of quantitative sampling of protein.
In this embodiment, one side fixedly connected with dead lever 15 of telescopic link 2, the one end fixedly connected with buckle ring 16 of dead lever 15, buckle ring 16 with sampling tube 9 contact is connected, is used for right the fixing of sampling tube 9, protruding magnetic path 4 with concave magnetic path 5 inter attraction is convenient for take off or install sampling tube 9.
In this embodiment, a sampling head 13 is disposed at one end of the sampling tube 9, so as to facilitate sampling of protein.
In this embodiment, the scale 14 is provided on the sampling tube 9, so as to facilitate quantitative sampling.
In this embodiment, the inner diameter of the ring plate 7 is smaller than the inner diameter of the sampling tube 9, so as to prevent the threaded rod 6 from contacting the sampling tube 9, and further prevent the inner wall of the sampling tube 9 from being worn.
In this embodiment, the inner diameter of the planar bearing 8 is the same as the inner diameter of the sampling tube 9, and the inner wall is flush, so that the planar bearing is detachably connected.
In this embodiment, the connecting rod 10 is fixedly sleeved with a baffle 12, the baffle 12 is rotationally connected with the sealing plate 11, and the threaded rod 6 drives the connecting rod 10 to rotate and drives the sealing plate 11 to move under the action of the baffle 12, so that the purpose of preventing the sealing plate 11 from rotating along with the threaded rod 6 is achieved.
Working principle: when the device is used, one end of a sampling head 13 is aligned with protein, then the ring plate 7 is rotated, as the convex magnetic block 4 is embedded with the concave magnetic block 5, the threaded rod 6 is kept fixed, meanwhile, the buckling ring 16 is buckled with the sampling tube 9, so that the sampling tube 9 is kept fixed, in the process of rotating the ring plate 7, the ring plate 7 and the threaded rod 6 are in threaded transmission, so that the threaded rod 6 moves upwards in parallel, meanwhile, the telescopic rod 2 extends upwards through the transmission of the top plate 3, meanwhile, the threaded rod 6 drives the sealing plate 11 to move upwards in parallel through the action of the connecting rod 10 and the blocking plate 12, meanwhile, the protein enters the sampling tube 9 through the sampling head 13 through the action of atmospheric pressure, and then the purpose of quantitatively sampling the protein is achieved according to the scale 14 on the observation sampling tube 9; the sampling tube 9 can be taken down from the convex magnetic block 4 and the clamping ring 16, so that the sampling tube 9 is separated from the clamping ring 16, meanwhile, the convex magnetic block 4 is separated from the concave magnetic block 5, then a user holds the sampling tube and the ring plate 7 by hand to keep the ring plate 7 fixed, then rotates the concave magnetic block 5, the concave magnetic block 5 drives the threaded rod 6 to rotate and drive with the threads of the ring plate 7, meanwhile, the threaded rod 6 drives the connecting rod 10 to rotate and drives the sealing plate 11 to move under the action of the baffle plate 12, so that the purpose of preventing the sealing plate 11 from rotating along with the threaded rod 6 is achieved, and protein sampling is realized.
Compared with the prior art, the utility model has the technical advantages that: the quantitative sampling of proteins can be realized through the cooperation of each component in two forms, so that the tightness of the sampling tube 9 is improved, the cleaning of the interior of the sampling tube 9 is facilitated, the purpose of reducing the abrasion of the sealing plate 11 is achieved, and the service life is prolonged.
Claims (7)
1. The utility model provides a protein ration sampling device for mass spectrum detection, its characterized in that, including base (1), sampling tube (9) and link plate (7), the top fixedly connected with plane bearing (8) of sampling tube (9), the top fixedly connected with link plate (7) of plane bearing (8), threaded connection has threaded rod (6) on link plate (7), the one end fixedly connected with connecting rod (10) of threaded rod (6), the one end rotation of connecting rod (10) is connected with closing plate (11), closing plate (11) with sampling tube (9) contact connection, the other end fixedly connected with concave magnet (5) of threaded rod (6), concave magnet (5) with link plate (7) contact connection, be equipped with telescopic link (2) on base (1), the top of telescopic link (2) is equipped with roof (3), the bottom fixed mounting of roof (3) has protruding magnet (4), protruding magnet (4) with concave magnet (5) gomphosis is connected.
2. The quantitative protein sampling device for mass spectrometry according to claim 1, wherein a fixing rod (15) is fixedly connected to one side of the telescopic rod (2), a clamping ring (16) is fixedly connected to one end of the fixing rod (15), the clamping ring (16) is in contact connection with the sampling tube (9), and the convex magnetic block (4) and the concave magnetic block (5) are attracted to each other.
3. A quantitative sampling device for detecting proteins by mass spectrometry according to claim 2, characterized in that one end of the sampling tube (9) is provided with a sampling head (13).
4. A protein quantitative sampling device for mass spectrometry according to claim 3, wherein the sampling tube (9) is provided with a scale (14).
5. The quantitative sampling device for protein for mass spectrometry according to claim 1, wherein the inner diameter of the annular plate (7) is smaller than the inner diameter of the sampling tube (9).
6. The quantitative sampling device for protein for mass spectrometry according to claim 5, wherein the inner diameter of the planar bearing (8) is the same as the inner diameter of the sampling tube (9) and the inner wall is flush.
7. The quantitative protein sampling device for mass spectrometry according to claim 1, wherein a baffle plate (12) is fixedly sleeved on the connecting rod (10), and the baffle plate (12) is rotatably connected with the sealing plate (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202323280019.XU CN221326029U (en) | 2023-12-04 | 2023-12-04 | Protein quantitative sampling device for mass spectrum detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202323280019.XU CN221326029U (en) | 2023-12-04 | 2023-12-04 | Protein quantitative sampling device for mass spectrum detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN221326029U true CN221326029U (en) | 2024-07-12 |
Family
ID=91786040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202323280019.XU Active CN221326029U (en) | 2023-12-04 | 2023-12-04 | Protein quantitative sampling device for mass spectrum detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN221326029U (en) |
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2023
- 2023-12-04 CN CN202323280019.XU patent/CN221326029U/en active Active
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