CN219922931U - Liquid nitrogen bulk drug reation kettle - Google Patents
Liquid nitrogen bulk drug reation kettle Download PDFInfo
- Publication number
- CN219922931U CN219922931U CN202320945476.7U CN202320945476U CN219922931U CN 219922931 U CN219922931 U CN 219922931U CN 202320945476 U CN202320945476 U CN 202320945476U CN 219922931 U CN219922931 U CN 219922931U
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- Prior art keywords
- liquid nitrogen
- cleaning
- reaction kettle
- reaction
- pipe
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title claims abstract description 106
- 239000007788 liquid Substances 0.000 title claims abstract description 53
- 229910052757 nitrogen Inorganic materials 0.000 title claims abstract description 53
- 239000003814 drug Substances 0.000 title claims abstract description 17
- 229940079593 drug Drugs 0.000 title claims abstract description 17
- 238000009434 installation Methods 0.000 claims abstract description 26
- 239000011229 interlayer Substances 0.000 claims abstract description 12
- 238000004140 cleaning Methods 0.000 claims description 85
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
- 238000005485 electric heating Methods 0.000 claims description 19
- 238000003756 stirring Methods 0.000 claims description 13
- 238000007599 discharging Methods 0.000 claims description 8
- 239000007921 spray Substances 0.000 claims description 6
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 239000008186 active pharmaceutical agent Substances 0.000 claims 5
- 229940088679 drug related substance Drugs 0.000 claims 5
- 238000001816 cooling Methods 0.000 abstract description 9
- 239000010410 layer Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 6
- 238000004519 manufacturing process Methods 0.000 description 7
- 239000002994 raw material Substances 0.000 description 6
- 239000000498 cooling water Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
The utility model discloses a liquid nitrogen bulk drug reaction kettle, which comprises a reaction kettle body and a reaction cabin body suspended and fixed in the reaction kettle body, wherein an installation area is arranged between the reaction kettle body and the reaction cabin body; and the left side of the lower end of the installation area is provided with a liquid nitrogen box, a liquid nitrogen pump is installed in the liquid nitrogen box, the bulkhead of the reaction cabin body is provided with an interlayer, the liquid nitrogen pump is correspondingly communicated with the interlayer inside the bulkhead through a set pipeline, and liquid nitrogen can be injected into the interlayer of the reaction cabin body through the liquid nitrogen pump. This device includes the reaction kettle body of outside and unsettled setting at this internal reaction cabin of reaction kettle to can constitute the installation region of inside, can be convenient set up the liquid nitrogen box in the installation region, correspond in the liquid nitrogen box and set up the liquid nitrogen pump, set up the bulkhead of the reaction cabin body into the intermediate layer formula structure simultaneously, pour into the intermediate layer with liquid nitrogen into, can cool off the internal temperature of the reaction cabin body rapidly through the intermediate layer, the cooling effect is very good, and each mechanism installation etc. is all very reasonable.
Description
Technical Field
The utility model relates to reaction kettle technical equipment in the chemical industry field, in particular to a liquid nitrogen bulk drug reaction kettle.
Background
In the prior art, the drug production refers to the process of processing raw materials into drugs capable of being used for medical treatment, the production process can be generally divided into a raw material drug production stage and a preparation production stage of preparing the raw material drug into a certain dosage form, and the reaction kettle is one of the common devices in the raw material drug production stage, and the drug preparation is finally prepared by adding and mixing the drug raw materials into the reaction kettle and providing reaction conditions.
In the prior art, a cooling device of a reaction kettle is generally characterized in that a plurality of circles of pipelines are arranged on the inner wall of the reaction kettle in a coiled pipe, cooling water is filled into the coiled pipe through refrigerating equipment, and a water pump is arranged outside the cooling device for water circulation; the whole water circulation structure of the cooling device is closed, so that the whole process is carried out in the pipeline; in the cooling process, the cooling water is difficult to exchange heat with the outside, and the temperature of the cooling water cannot be quickly reduced; the cooling effect is slow and the effect is poor.
On the other hand, the inside of the existing reaction kettle is very troublesome in cleaning, the inside of the reaction kettle cannot be well cleaned, and after the reaction kettle is cleaned, most reaction kettle devices cannot dry the inside of the reaction kettle, and the reaction kettle needs to be naturally air-dried, so that the follow-up work can be greatly affected.
Therefore, in order to solve the above problems, it is necessary to develop a liquid nitrogen bulk drug reaction kettle with good cooling effect and convenient cleaning.
Disclosure of Invention
The utility model aims at overcoming the defects in the prior art and provides a liquid nitrogen bulk drug reaction kettle; the technical scheme is as follows:
a liquid nitrogen bulk drug reaction kettle comprises a reaction kettle body and a reaction cabin body which is suspended and fixed in the reaction kettle body, wherein an installation area is arranged between the reaction kettle body and the reaction cabin body; the left side of the lower end of the installation area is provided with a liquid nitrogen box, a liquid nitrogen pump is arranged in the liquid nitrogen box, the bulkhead of the reaction cabin body is provided with an interlayer, the liquid nitrogen pump is correspondingly communicated with the interlayer in the bulkhead through a pipeline, and liquid nitrogen can be injected into the interlayer of the reaction cabin body through the liquid nitrogen pump;
the right side of the lower end of the installation area is also provided with a water tank, and a water pump is correspondingly installed in the water tank; the inner side of the upper end of the reaction cabin body is fixedly provided with a cleaning box, a cleaning pipe is arranged in the cleaning box, the cleaning pipe is provided with a cleaning joint, the water pump is provided with a water pipe, and the water pipe extends upwards into the cleaning box to be correspondingly communicated with the cleaning joint;
the cleaning pipe extend to be arranged in the cleaning box, and the cleaning nozzle is correspondingly arranged on the cleaning pipe, the cleaning nozzle extends out of the cleaning box to the reaction cabin body, and the cleaning nozzle is distributed on the peripheral side wall and the lower end panel of the cleaning box and can clean the internal space of the reaction cabin body.
Further, the inner side of the upper end of the cleaning box is also provided with an electric push rod, the electric push rod is also provided with a push plate, the lower end face of the push plate is also correspondingly provided with an electric heating dryer, the lower end of the cleaning box is also provided with a valve pipe at a corresponding position, and when the valve pipe is opened, the electric push rod can push the electric heating dryer out of the cleaning box.
Further, the upper end of the reaction kettle body is also provided with a stirring motor, a main shaft of the stirring motor extends downwards into the reaction cabin body, and stirring blades are correspondingly arranged on the main shaft; and the setting position of the cleaning box and the position of the main shaft are not mutually influenced.
Further, a feed inlet is also arranged on the reaction kettle body, and extends into the reaction cabin body; the lower end of the reaction cabin body is also provided with a discharging pipe which extends to the outer side of the reaction kettle body, and the pipe orifice is provided with a connecting flange.
Further, a first electromagnetic valve is arranged at the feed inlet; and a second electromagnetic valve is arranged on the discharging pipe.
Further, the electric control device also comprises a controller, wherein the controller is arranged on the outer wall of the reaction kettle body, and the controller correspondingly provides power supplies for the internal electric push rod and the electric heating dryer and can correspondingly control the electric push rod and the electric heating dryer.
Further, the outside of reation kettle body still is provided with the fixed station, installs the support base on this fixed station.
The beneficial effects are that: the utility model has the following beneficial effects:
1) The device adopts a double-layer bin body structure, comprises an external reaction kettle body and a reaction bin body which is suspended in the reaction kettle body, so that an internal installation area can be formed, a liquid nitrogen box is conveniently arranged in the installation area, a liquid nitrogen pump is correspondingly arranged in the liquid nitrogen box, meanwhile, the bulkhead of the reaction bin body is arranged into a sandwich structure, liquid nitrogen is injected into the sandwich layer, the internal temperature of the reaction bin body can be rapidly cooled through the sandwich layer, the cooling effect is very good, and the installation of each mechanism is quite reasonable;
2) The liquid nitrogen box can be installed in the installation area, the water tank, the water pump and the like can be installed, the cleaning box is installed on the inner wall of the upper end of the reaction cabin body, the cleaning pipe, the cleaning joint and the cleaning nozzle are arranged in the cleaning box, clean water in the water tank can be sent into the cleaning box and sprayed out of the cleaning nozzle, so that the interior of the reaction cabin body is cleaned, and the efficient cleaning can be realized by correspondingly matching with the stirring blades and the like, the cleaning efficiency is very high, the structural installation is reasonable, and the use is convenient;
3) The electric push rod is arranged in the cleaning box, the push plate is arranged on the electric push rod, the electric heating dryer is correspondingly arranged on the push plate, the electric heating dryer can be designed into an electric heating blower and the like, meanwhile, a valve pipe corresponding to the position is arranged at the lower end of the cleaning box, after the cleaning is finished, the valve pipe is opened, the electric heating blower on the push plate is pushed out of the cleaning box through the electric push rod, then air is blown, the inside of the reaction cabin body can be quickly dried, the device can be rapidly put into new work, and the production efficiency is improved.
Drawings
FIG. 1 is a block diagram of the present utility model;
FIG. 2 is an internal structural diagram of the present utility model;
fig. 3 is an enlarged view at a in fig. 2.
Detailed Description
The utility model will be further illustrated by the following drawings and specific examples, which are carried out on the basis of the technical solutions of the utility model, it being understood that these examples are only intended to illustrate the utility model and are not intended to limit the scope of the utility model.
As shown in fig. 1, 2 and 3, the liquid nitrogen bulk drug reaction kettle comprises a reaction kettle body 1 and a reaction cabin 14 suspended and fixed in the reaction kettle body 1, wherein an installation area 2 is arranged between the reaction kettle body 1 and the reaction cabin 14; and the left side of the lower end of the installation area 2 is provided with a liquid nitrogen box 28, a liquid nitrogen pump 27 is installed in the liquid nitrogen box 28, the bulkhead of the reaction cabin body 14 is provided with an interlayer, the liquid nitrogen pump 27 is correspondingly communicated with the interlayer inside the bulkhead through a pipeline, and liquid nitrogen can be injected into the interlayer of the reaction cabin body 14 through the liquid nitrogen pump 27.
This device adopts double-deck storehouse body structure, including the reaction kettle body of outside and unsettled reaction cabin body that sets up in the reaction kettle body to can constitute inside installation region, can be convenient set up the liquid nitrogen box in the installation region, correspond in the liquid nitrogen box and set up the liquid nitrogen pump, set up the bulkhead of the reaction cabin body into sandwich structure simultaneously, pour into the intermediate layer with liquid nitrogen into, can cool off the internal temperature of the reaction cabin body rapidly through the intermediate layer, the cooling effect is very good, and each mechanism installation etc. is all very reasonable.
The right side of the lower end of the installation area 2 is also provided with a water tank 16, and a water pump 17 is correspondingly installed in the water tank 16; and the inner side of the upper end of the reaction chamber body 14 is fixedly provided with a cleaning box 23, a cleaning pipe 10 is arranged in the cleaning box 23, the cleaning pipe 10 is provided with a cleaning joint 24, the water pump 17 is provided with a water pipe 15, and the water pipe 15 extends upwards into the cleaning box 23 to be correspondingly communicated with the cleaning joint 24.
The cleaning pipe 10 is arranged in the cleaning box 23 in an extending mode, cleaning spray heads 26 are correspondingly arranged on the cleaning pipe 10, the cleaning spray heads 26 extend out of the cleaning box 23 into the reaction chamber body 14, the cleaning spray heads 26 are distributed on the peripheral side walls and the lower end face plate of the cleaning box 23, and therefore the inner space of the reaction chamber body 14 can be cleaned.
The liquid nitrogen box can be installed in the installation area in the device, the water tank can be installed simultaneously, the water pump is arranged, the cleaning box is installed on the inner wall of the upper end of the reaction cabin body, the cleaning pipe, the cleaning joint and the cleaning nozzle are arranged in the cleaning box, clear water in the water tank can be sent into the cleaning box to be sprayed out from the cleaning nozzle, so that the reaction cabin body is cleaned, the efficient cleaning can be realized by corresponding matching with the stirring blades, the cleaning efficiency is very high, the structural installation is reasonable, and the use is convenient.
The electric push rod 20 is further installed on the inner side of the upper end of the cleaning box 23, the pushing plate 21 is further installed on the electric push rod 20, the electric heating dryer 22 is correspondingly installed on the lower end face of the pushing plate 21, the valve pipe 19 is further arranged at the position corresponding to the lower end of the cleaning box 23, and when the valve pipe 19 is opened, the electric push rod 20 can push the electric heating dryer 22 out of the cleaning box 23.
The electric push rod is arranged in the cleaning box, the push plate is arranged on the electric push rod, the electric heating dryer is correspondingly arranged on the push plate, the electric heating dryer can be designed into an electric heating blower and the like, meanwhile, a valve pipe corresponding to the position is arranged at the lower end of the cleaning box, after the cleaning is finished, the valve pipe is opened, the electric heating blower on the push plate is pushed out of the cleaning box through the electric push rod, then air is blown, the inside of the reaction cabin body can be quickly dried, the device can be rapidly put into new work, and the production efficiency is improved.
The upper end of the reaction kettle body 1 is also provided with a stirring motor 11, a main shaft 12 of the stirring motor 11 extends downwards into a reaction cabin 14, and stirring blades 13 are correspondingly arranged on the main shaft 12; and the installation position of the cleaning tank 23 and the position of the main shaft 12 do not affect each other.
The reaction kettle body 1 is also provided with a feed inlet 7, and the feed inlet 7 extends into the reaction cabin 14; the lower end of the reaction cabin body 14 is also provided with a discharging pipe 5, the discharging pipe 5 extends to the outer side of the reaction kettle body 1, and a pipe orifice is provided with a connecting flange 8.
A first electromagnetic valve 9 is arranged at the feed inlet 7; the discharging pipe 5 is provided with a second electromagnetic valve 18.
The electric control device also comprises a controller 6, wherein the controller 6 is arranged on the outer wall of the reaction kettle body 1, and the controller 6 correspondingly provides power sources for the electric push rod 20 and the electric dryer 22, and can correspondingly control the electric push rod 20 and the electric dryer 22.
The outside of reation kettle body 1 still is provided with fixed station 3, installs support base 4 on this fixed station 3.
The device is also provided with a stirring motor and the like for accelerating stirring when the raw materials react; meanwhile, a feed inlet and a discharge outlet are designed, and a controller and the like are designed, so that the processing control of each part can be more convenient.
The above detailed description is only a preferred embodiment of the present utility model and is not intended to limit the scope of the claims, but all equivalent changes and modifications that can be made according to the protection scope of the claims are included in the scope of the claims.
Claims (7)
1. A liquid nitrogen bulk drug reation kettle, its characterized in that: comprises a reaction kettle body (1) and a reaction cabin (14) suspended and fixed in the reaction kettle body (1), wherein an installation area (2) is arranged between the reaction kettle body (1) and the reaction cabin (14); the left side of the lower end of the installation area (2) is provided with a liquid nitrogen box (28), a liquid nitrogen pump (27) is installed in the liquid nitrogen box (28), the bulkhead of the reaction cabin body (14) is provided with an interlayer, the liquid nitrogen pump (27) is correspondingly communicated with the interlayer in the bulkhead through a arranged pipeline, and liquid nitrogen can be injected into the interlayer of the reaction cabin body (14) through the liquid nitrogen pump (27);
the right side of the lower end of the installation area (2) is also provided with a water tank (16), and a water pump (17) is correspondingly installed in the water tank (16); the inner side of the upper end of the reaction cabin body (14) is fixedly provided with a cleaning box (23), a cleaning pipe (10) is arranged in the cleaning box (23), the cleaning pipe (10) is provided with a cleaning joint (24), the water pump (17) is provided with a water pipe (15), and the water pipe (15) extends upwards into the cleaning box (23) to be correspondingly communicated with the cleaning joint (24);
the cleaning pipe (10) extend to be arranged in the cleaning box (23), cleaning spray heads (26) are correspondingly arranged on the cleaning pipe (10), the cleaning spray heads (26) extend out of the cleaning box (23) into the reaction cabin body (14), and the cleaning spray heads (26) are distributed on the peripheral side wall and the lower end panel of the cleaning box (23) and can clean the inner space of the reaction cabin body (14).
2. The liquid nitrogen drug substance reaction kettle as defined in claim 1 is characterized in that: the electric dryer is characterized in that an electric push rod (20) is further arranged on the inner side of the upper end of the cleaning box (23), a pushing plate (21) is further arranged on the electric push rod (20), an electric heating dryer (22) is further correspondingly arranged on the lower end face of the pushing plate (21), a valve pipe (19) is further arranged at the corresponding position of the lower end of the cleaning box (23), and when the valve pipe (19) is opened, the electric push rod (20) can push the electric heating dryer (22) out of the cleaning box (23).
3. The liquid nitrogen drug substance reaction kettle as defined in claim 1 is characterized in that: the upper end of the reaction kettle body (1) is also provided with a stirring motor (11), a main shaft (12) of the stirring motor (11) extends downwards into the reaction cabin (14), and stirring blades (13) are correspondingly arranged on the main shaft (12); and the installation position of the cleaning box (23) and the position of the main shaft (12) are not mutually influenced.
4. The liquid nitrogen drug substance reaction kettle as defined in claim 1 is characterized in that: a feed inlet (7) is also arranged on the reaction kettle body (1), and the feed inlet (7) extends into the reaction cabin body (14); the lower extreme of reaction cabin body (14) still installs discharging pipe (5), and discharging pipe (5) extend to the outside of reation kettle body (1), and mouth of pipe installs flange (8).
5. The liquid nitrogen drug substance reaction kettle as defined in claim 4 is characterized in that: a first electromagnetic valve (9) is arranged at the feed inlet (7); the discharging pipe (5) is provided with a second electromagnetic valve (18).
6. A liquid nitrogen bulk drug reaction kettle as claimed in claim 2, wherein: the electric heating device further comprises a controller (6), wherein the controller (6) is arranged on the outer wall of the reaction kettle body (1), and the controller (6) correspondingly provides power for the electric push rod (20) and the electric heating dryer (22) and can correspondingly control the electric push rod (20) and the electric heating dryer (22).
7. The liquid nitrogen drug substance reaction kettle as defined in claim 1 is characterized in that: the outside of reation kettle body (1) still is provided with fixed station (3), installs on this fixed station (3) and supports base (4).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320945476.7U CN219922931U (en) | 2023-04-24 | 2023-04-24 | Liquid nitrogen bulk drug reation kettle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320945476.7U CN219922931U (en) | 2023-04-24 | 2023-04-24 | Liquid nitrogen bulk drug reation kettle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219922931U true CN219922931U (en) | 2023-10-31 |
Family
ID=88499543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320945476.7U Active CN219922931U (en) | 2023-04-24 | 2023-04-24 | Liquid nitrogen bulk drug reation kettle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219922931U (en) |
-
2023
- 2023-04-24 CN CN202320945476.7U patent/CN219922931U/en active Active
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