CN219721963U - Recrystallization device for purifying drug impurities - Google Patents
Recrystallization device for purifying drug impurities Download PDFInfo
- Publication number
- CN219721963U CN219721963U CN202320392569.1U CN202320392569U CN219721963U CN 219721963 U CN219721963 U CN 219721963U CN 202320392569 U CN202320392569 U CN 202320392569U CN 219721963 U CN219721963 U CN 219721963U
- Authority
- CN
- China
- Prior art keywords
- purifying
- tank
- motor
- filter screen
- recrystallization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012535 impurity Substances 0.000 title claims abstract description 62
- 239000003814 drug Substances 0.000 title claims abstract description 36
- 238000001953 recrystallisation Methods 0.000 title claims abstract description 23
- 229940079593 drug Drugs 0.000 title claims abstract description 11
- 238000003756 stirring Methods 0.000 claims abstract description 25
- 238000007790 scraping Methods 0.000 claims abstract description 14
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 10
- 229910052799 carbon Inorganic materials 0.000 claims description 10
- 238000002425 crystallisation Methods 0.000 abstract description 8
- 230000008025 crystallization Effects 0.000 abstract description 8
- OKTJSMMVPCPJKN-BJUDXGSMSA-N carbon-11 Chemical class [11C] OKTJSMMVPCPJKN-BJUDXGSMSA-N 0.000 description 7
- 230000000903 blocking effect Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 230000007547 defect Effects 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
Landscapes
- Centrifugal Separators (AREA)
Abstract
The utility model discloses a recrystallization device for purifying drug impurities, which comprises an impurity removing tank, a crystallization tank, a communicating pipe, a cross rod, a centrifugal impurity removing device and a stirring scraping device, wherein the crystallization tank is arranged on one side of the impurity removing tank, the communicating pipe is communicated with the impurity removing tank and the crystallization tank, the cross rod is arranged in the impurity removing tank, the centrifugal impurity removing device is arranged in the impurity removing tank and rotates on the cross rod, and the stirring scraping device is arranged in the centrifugal impurity removing device. The utility model belongs to the technical field of medicine impurity removal, and particularly relates to a recrystallization device for purifying medicine impurities, which can rapidly remove impurities in medicines and improve efficiency.
Description
Technical Field
The utility model belongs to the technical field of medicine impurity removal, and particularly relates to a recrystallization device for purifying medicine impurities.
Background
Recrystallization is a process of dissolving crystals in a solvent or melting and then crystallizing again from the solution or melt, and can purify impure substances, so that insoluble powder impurities mixed in the medicine are often difficult to remove due to various considerable reasons in the preparation process of the medicine, and in order to avoid the influence of the impurities on the medicine, the medicine must be subjected to storage treatment, and the medicine is searched, and the method disclosed in (bulletin) No.: CN210612934U discloses a recrystallization device for purifying impurities in medicines, which has simple structure and convenient use, and is provided with a corresponding stirring device, and the motor can be controlled by a control switch group to work so as to drive the stirring device to work, thereby ensuring the dissolution of medicines, effectively avoiding the defect that the traditional medicines are required to be stirred manually in recrystallization, effectively reducing the labor load of users, simultaneously ensuring the dissolution efficiency of the medicines, and further ensuring the recrystallization purification efficiency of the medicines, however, the device has the following defects: when the medicine is filtered and filtered for impurity removal, the active carbon is removed by normal pressure permeation, so that the efficiency is very low, and on the basis of the efficiency, improvement is needed.
Disclosure of Invention
In order to solve the problems, the utility model provides a recrystallization device for purifying the impurities in the medicine, which can rapidly remove the impurities in the medicine and improve the efficiency.
In order to realize the functions, the technical scheme adopted by the utility model is as follows: the utility model provides a recrystallization device of purification medicine impurity, includes edulcoration jar, crystallizer, communicating pipe, horizontal pole, centrifugal edulcoration device and stirring scraping device, the crystallizer is located one side of edulcoration jar, communicating pipe intercommunication edulcoration jar and crystallizer, the inside of edulcoration jar is located to the horizontal pole, centrifugal edulcoration device locates the inside of edulcoration jar and rotates on the horizontal pole, stirring scraping device locates the inside of centrifugal edulcoration device; centrifugal edulcoration device includes motor one, pivot, layer board, filter screen, active carbon, electric putter, connecting block and apron, the bottom of edulcoration jar is located to motor one, the power take off end of motor one is located to the pivot and runs through and rotate in the horizontal pole, the upper end of pivot is located to the layer board, the filter screen is located on the layer board and the interval is equipped with the multiunit, between the filter screen was located to the active carbon, the upper end of edulcoration jar is located to electric putter, electric putter's output is located to the connecting block, the apron covers on filter screen and active carbon and with connecting block sliding connection, through adding the medicine to the filter screen in, covers the fastening to active carbon and filter screen through the apron, and centrifugal motion is done to pivot drive filter screen and active carbon, can accelerate the filtration edulcoration of medicine.
Further, stirring is scraped brush device and is included motor two, puddler, connecting rod and brush, the upper end of edulcoration jar is located to motor two, the puddler is located motor two's power take off end and is located the inside of filter screen, the connecting rod is located on the puddler, the brush is located on the connecting rod and can scrape the brush to the inner wall of the filter screen of innermost, can avoid impurity to block up the filter screen of innermost through scraping the brush, improves filterable speed.
Preferably, the cover plate is disc-shaped.
Preferably, a chute is arranged on the cover plate, the connecting block slides in the chute, and the vertical section of the chute is in a T-shaped arrangement.
Preferably, the electric push rod circumferential array is provided with a plurality of groups.
Preferably, the communicating pipe is provided with an electromagnetic valve.
Preferably, the first motor and the second motor are servo motors.
The utility model adopts the structure to obtain the beneficial effects as follows: according to the recrystallization device for purifying the medicine impurities, provided by the utility model, the centrifugal impurity removing device is arranged, so that the medicine is filtered and impurity removed in a centrifugal state, the efficiency of purifying and impurity removing the medicine is greatly improved, the stirring scraping device can continuously stir the medicine needing to be filtered and impurity removed, and meanwhile, the impurity can be prevented from blocking the filter screen at the innermost layer.
Drawings
FIG. 1 is a schematic diagram showing the overall structure of a recrystallization apparatus for purifying pharmaceutical impurities according to the present utility model;
FIG. 2 is a top view of a cover plate of a recrystallization apparatus for purifying pharmaceutical impurities according to the present utility model.
Wherein, 1, a impurity removing tank, 2, a crystallization tank, 3, a communicating pipe, 4, a cross rod, 5, a centrifugal impurity removing device, 6, a stirring scraping and brushing device, 7, a motor I, 8, a rotating shaft, 9 and a supporting plate, 10, a filter screen, 11, active carbon, 12, an electric push rod, 13, a connecting block, 14, a cover plate, 15, a second motor, 16, a stirring rod, 17, a connecting rod, 18, a brush, 19, a chute, 20 and an electromagnetic valve.
Detailed Description
The following description of the embodiments of the present utility model will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the utility model are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In the description of the present utility model, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. The present utility model will be described in further detail with reference to the accompanying drawings.
As shown in fig. 1-2, the recrystallization device for purifying drug impurities of the utility model comprises a impurity removing tank 1, a crystallization tank 2, a communicating pipe 3, a cross rod 4, a centrifugal impurity removing device 5 and a stirring scraping device 6, wherein the crystallization tank 2 is arranged on one side of the impurity removing tank 1, the communicating pipe 3 is communicated with the impurity removing tank 1 and the crystallization tank 2, the cross rod 4 is arranged in the impurity removing tank 1, the centrifugal impurity removing device 5 is arranged in the impurity removing tank 1 and rotates on the cross rod 4, and the stirring scraping device 6 is arranged in the centrifugal impurity removing device 5; the centrifugal impurity removing device 5 comprises a motor I7, a rotating shaft 8, a supporting plate 9, a filter screen 10, activated carbon 11, an electric push rod 12, a connecting block 13 and a cover plate 14, wherein the motor I7 is arranged at the bottom of the impurity removing tank 1, the rotating shaft 8 is arranged at the power output end of the motor I7 and penetrates through and rotates in the cross rod 4, the supporting plate 9 is arranged at the upper end of the rotating shaft 8, the filter screen 10 is arranged on the supporting plate 9 and is provided with a plurality of groups at intervals, the activated carbon 11 is arranged between the filter screens 10, the electric push rod 12 is arranged at the upper end of the impurity removing tank 1, the connecting block 13 is arranged at the output end of the electric push rod 12, the cover plate 14 is covered on the filter screen 10 and the activated carbon 11 and is in sliding connection with the connecting block 13, the filter screen 10 is covered and fastened by the cover plate 14, and the rotating shaft 8 drives the filter screen 10 and the activated carbon 11 to do centrifugal motion, and the impurity removing of the medicines can be accelerated.
The stirring scraping brush device 6 comprises a motor II 15, a stirring rod 16, a connecting rod 17 and a brush 18, wherein the motor II 15 is arranged at the upper end of the impurity removal tank 1, the stirring rod 16 is arranged at the power output end of the motor II 15 and is positioned in the filter screen 10, the connecting rod 17 is arranged on the stirring rod 16, the brush 18 is arranged on the connecting rod 17 and can scrape the inner wall of the filter screen 10 at the innermost layer, impurities can be prevented from blocking the filter screen 10 at the innermost layer through scraping, and the filtering speed is improved.
The cover plate 14 is arranged in a disc shape.
The cover plate 14 is provided with a chute 19, the connecting block 13 slides in the chute 19, and the vertical section of the chute 19 is T-shaped.
The electric push rods 12 are arranged in a circumferential array in a plurality of groups.
The communication pipe 3 is provided with an electromagnetic valve 20.
The first motor 7 and the second motor 15 are servo motors.
When the device is specifically used, firstly, the electric push rod 12 is started, the cover plate 14 is opened upwards under the pulling of the connecting block 13, at the moment, the medicine solution needing impurity removal is added into the filter screen 10 at the innermost layer, then the cover plate 14 covers and presses the upper ends of the activated carbon 11 and the filter screen 10, the motor II 15 is started, the stirring rod 16 stirs the medicine solution, meanwhile, the connecting rod 17 drives the hairbrush 18 to scrape the filter screen 10 at the innermost layer, impurities are prevented from blocking the filter screen 10, the medicine solution flows into the lower end of the impurity removal tank 1 after being subjected to double filtration by the filter screen 10 and the activated carbon 11, the motor I7 is started, the rotating shaft 8 drives the supporting plate 9 to rotate, meanwhile, the filter screen 10, the activated carbon 11 and the cover plate 14 synchronously rotate to perform centrifugal motion, the medicine is thrown away under the centrifugal force, the medicine impurity removal efficiency is greatly improved, then the electromagnetic valve 20 is opened, and the medicine after impurity removal enters the crystallization tank 2 through the communicating pipe 3 for recrystallization.
The utility model and its embodiments have been described above with no limitation, and the actual construction is not limited to the embodiments of the utility model as shown in the drawings. In summary, if one of ordinary skill in the art is informed by this disclosure, a structural manner and an embodiment similar to the technical solution should not be creatively devised without departing from the gist of the present utility model.
Claims (7)
1. A recrystallization device for purifying drug impurities, which is characterized in that: the device comprises a purifying tank (1), a crystallizing tank (2), a communicating pipe (3), a cross rod (4), a centrifugal purifying device (5) and a stirring scraping brush device (6), wherein the crystallizing tank (2) is arranged on one side of the purifying tank (1), the communicating pipe (3) is communicated with the purifying tank (1) and the crystallizing tank (2), the cross rod (4) is arranged in the purifying tank (1), the centrifugal purifying device (5) is arranged in the purifying tank (1) and rotates on the cross rod (4), and the stirring scraping brush device (6) is arranged in the centrifugal purifying device (5); centrifugal edulcoration device (5) include motor one (7), pivot (8), layer board (9), filter screen (10), active carbon (11), electric putter (12), connecting block (13) and apron (14), the bottom of edulcoration jar (1) is located to motor one (7), the power take off end of motor one (7) is located in pivot (8) and runs through and rotate in horizontal pole (4), the upper end of pivot (8) is located to layer board (9), filter screen (10) are located on layer board (9) and the interval is equipped with the multiunit, active carbon (11) are located between filter screen (10), the upper end of edulcoration jar (1) is located to electric putter (12) is located to connecting block (13), apron (14) cover on filter screen (10) and active carbon (11) and with connecting block (13) sliding connection.
2. A recrystallization apparatus for purifying pharmaceutical impurities according to claim 1, wherein: the stirring scraping brush device (6) comprises a motor II (15), a stirring rod (16), a connecting rod (17) and a brush (18), wherein the motor II (15) is arranged at the upper end of the impurity removal tank (1), the stirring rod (16) is arranged at the power output end of the motor II (15) and is positioned in the filter screen (10), the connecting rod (17) is arranged on the stirring rod (16), and the brush (18) is arranged on the connecting rod (17) and can scrape the inner wall of the filter screen (10) at the innermost layer.
3. A recrystallization apparatus for purifying pharmaceutical impurities according to claim 2, wherein: the cover plate (14) is arranged in a disc shape.
4. A recrystallization apparatus for purifying pharmaceutical impurities according to claim 3, wherein: the cover plate (14) is provided with a chute (19), the connecting block (13) slides in the chute (19), and the vertical section of the chute (19) is in a T-shaped arrangement.
5. The recrystallization apparatus for purifying pharmaceutical impurities according to claim 4, wherein: the electric push rods (12) are arranged in a circumferential array manner in a plurality of groups.
6. A recrystallization apparatus for purifying pharmaceutical impurities according to claim 5, wherein: the communicating pipe (3) is provided with an electromagnetic valve (20).
7. A recrystallization apparatus for purifying pharmaceutical impurities according to claim 6, wherein: the first motor (7) and the second motor (15) are servo motors.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320392569.1U CN219721963U (en) | 2023-03-06 | 2023-03-06 | Recrystallization device for purifying drug impurities |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320392569.1U CN219721963U (en) | 2023-03-06 | 2023-03-06 | Recrystallization device for purifying drug impurities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219721963U true CN219721963U (en) | 2023-09-22 |
Family
ID=88058671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320392569.1U Active CN219721963U (en) | 2023-03-06 | 2023-03-06 | Recrystallization device for purifying drug impurities |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219721963U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118925272A (en) * | 2024-10-12 | 2024-11-12 | 安徽瑞邦生物科技有限公司 | A kind of L-valine purification equipment and purification method |
| CN119425145A (en) * | 2025-01-07 | 2025-02-14 | 河南正宇药业有限公司 | Rapid crystallization device of clindamycin phosphate |
-
2023
- 2023-03-06 CN CN202320392569.1U patent/CN219721963U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118925272A (en) * | 2024-10-12 | 2024-11-12 | 安徽瑞邦生物科技有限公司 | A kind of L-valine purification equipment and purification method |
| CN118925272B (en) * | 2024-10-12 | 2025-01-28 | 安徽瑞邦生物科技有限公司 | A kind of L-valine purification equipment and purification method |
| CN119425145A (en) * | 2025-01-07 | 2025-02-14 | 河南正宇药业有限公司 | Rapid crystallization device of clindamycin phosphate |
| CN119425145B (en) * | 2025-01-07 | 2025-07-18 | 河南正宇药业有限公司 | Rapid crystallization device of clindamycin phosphate |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN219721963U (en) | Recrystallization device for purifying drug impurities | |
| CN219072123U (en) | Drug impurity recrystallization device | |
| CN222605445U (en) | Recrystallization device | |
| CN117185444B (en) | Method for treating oxalic acid precipitation wastewater and ammonia nitrogen wastewater of rare earth separation plant and simultaneously recycling rare earth | |
| CN217774139U (en) | Hydrolysis reaction device for raw material medicine synthesis | |
| CN215030083U (en) | Lower discharging type centrifugal machine | |
| CN222777634U (en) | Alumina chemical raw material impurity removal agitator | |
| CN206731029U (en) | A kind of honey processing agitating device | |
| CN215693244U (en) | Traditional chinese medicine is traditional chinese medicine dissolving and filtering device for analysis | |
| CN213885027U (en) | Purification device based on organic intermediate impurity of medicine | |
| CN217757664U (en) | Copper device is carried in regeneration of little etching solution | |
| CN218961814U (en) | Crystallization purification device | |
| CN219744140U (en) | Residue filtering and recycling equipment for pear vinegar production process | |
| CN213527729U (en) | Medicine purification device | |
| CN223747007U (en) | A recrystallization apparatus for the synthesis of hydroxypinazone retinate | |
| CN222677366U (en) | A filtering device for building water supply and drainage | |
| CN220513643U (en) | Solid-liquid separation device for medicine processing | |
| CN218962323U (en) | Purifying equipment for nanoscale oral whitening pills | |
| CN219836767U (en) | Filter equipment is used in production of medicine midbody | |
| CN221491723U (en) | Liquid medicine filtering device for freeze-dried powder injection product | |
| CN219898172U (en) | Reaction barrel stirring device | |
| CN219744075U (en) | Coating filter equipment is used in cable processing | |
| CN217051847U (en) | Efficient S type pipeline sewage treatment sedimentation tank | |
| CN114797547B (en) | Liquid feeding device is used in production of high-purity strontium compound, barium compound solution | |
| CN222266269U (en) | Convenient-to-detach polyaluminum ferric chloride production filtration equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |