CN218832843U - Chemotherapy device with chemotherapy bag subcutaneously preset in ventricle catheter - Google Patents

Abstract

The utility model relates to the technical field of medical devices, in particular to a chemotherapy device with a subcutaneously preset chemotherapy bag for intraventricular catheterization, comprising a puncture drainage tube and a needle core, the puncture drainage tube is provided with a skull fixing plate, and the skull fixing plate A drainage tube hole is opened on the top, and the puncture and drainage tube passes through the drainage tube hole. The end of the puncture and drainage tube is connected with a subcutaneous external chemotherapy bag, and the subcutaneous external chemotherapy bag includes a base, latex skin, and a fixed cover. and the convex connection port, the latex skin is arranged between the base and the fixed cover, and the puncture drainage tube is connected with the convex connection port. The utility model can be drilled and punctured directly into the ventricle, and the end of the ventricle can be placed subcutaneously and sealed, and can be repeatedly percutaneously punctured, and can be repeatedly punctured into the ventricle without needing to be punctured again.

Description

A chemotherapy device with a subcutaneously preset chemotherapy bag for intraventricular catheterization

technical field

The utility model relates to the technical field of medical devices, in particular to a chemotherapy device with a subcutaneously preset chemotherapy bag inserted into a ventricle.

Background technique

Chemotherapy is one of the main treatment methods for malignant brain tumors. The commonly used chemotherapy methods are oral or intravenous chemotherapy. However, due to the existence of the blood-brain barrier, macromolecular and non-fat-soluble chemotherapy drugs are difficult to enter the brain to reach a sufficient therapeutic concentration, thereby Affects the efficacy of chemotherapy for brain tumors. The blood-brain barrier is a structure formed by vascular endothelial cells, pericytes, basement membrane, and glial cells. It is a selectively permeable barrier that can block the entry of harmful substances and protect brain tissue. But in the treatment of brain tumors, the blood-brain barrier prevents the entry of chemotherapy drugs. Many chemotherapy or targeted drugs that can effectively kill glioma in vitro cannot be applied clinically because they cannot effectively cross the blood-brain barrier. Intrathecal injection of chemotherapy or intraventricular chemotherapy by implantation of ommaya sac, chemotherapy slow-release tablets locally attached to the surgical area and other local administration methods can effectively avoid the blood-brain barrier, significantly increase the range of chemotherapy drugs for brain tumors, and reduce the risk of chemotherapy. Drug systemic side effects. For certain brain tumors such as meningeal metastases or tumors breaking through the ventricle and brain surface, on the basis of conventional oral and intravenous chemotherapy, intrathecal chemotherapy is often used in combination so that the chemotherapy drugs can directly enter the cerebrospinal fluid system and escape the blood. The blocking of chemotherapeutic drugs by the brain barrier structure can make the chemotherapeutic drugs directly enter the tumor through the cerebrospinal fluid-brain barrier to achieve greater local blood drug concentration. Therefore, although intrathecal chemotherapy is inconvenient and invasive in operation, it still exists as a supplementary chemotherapy. However, there are great disadvantages in intrathecal chemotherapy: First, lumbar puncture or lumbar cistern catheterization must be performed every time chemotherapy is performed. Repeated lumbar punctures may cause risks such as trauma and infection, and local adhesions are also a burden for multiple punctures. tube brings difficulty. Second: intrathecal chemotherapy must allow chemotherapy drugs to be injected into the lumbar cistern, and then gradually penetrate into the cistern magna and the surface of the brain through drug penetration, which has a poor effect on the penetration of tumor drugs in the ventricular system. Third: Because the cerebrospinal fluid circulation in the lumbar spinal canal is poorer than that in the brain, there is a difference between the drug concentration in the local cerebrospinal fluid and the drug concentration that penetrates into the brain surface, and the stimulation and damage of the spinal cord by high concentrations of chemotherapy drugs will bring certain functions obstacle. Fourth: The place where the lumbar spinal canal is placed is likely to cause extradural leakage, and part of the cerebrospinal fluid leaks into the epidural. During chemotherapy, it may cause extravasation of chemotherapy drugs into the epidural. On the other hand, the implantation of the ommaya sac requires the front end of the chemotherapy sac to be directly inserted into the tumor cavity or ventricle during the operation. It does not have a puncture function, and the end cannot be implanted into the ventricular system by conventional puncture methods.

Contents of the invention

In order to solve the above problems, the utility model provides a chemotherapy device with subcutaneously preset chemotherapy capsules placed in the ventricle. The device can be drilled and punctured directly into the ventricle, and its end can be placed subcutaneously and sealed, and can be repeatedly percutaneously punctured. .

In order to achieve the above object, the technical solution of the utility model is:

A chemotherapeutic device with a subcutaneous chemotherapy bag placed in the ventricle, comprising a puncture drainage tube and a needle core, the maximum diameter of the needle core is equal to the inner diameter of the puncture drainage tube, and the length is greater than the length of the puncture drainage tube, and the puncture drainage tube is provided with The cranium fixation plate is provided with a drainage tube hole, the puncture drainage tube passes through the drainage tube hole, the end of the puncture drainage tube is connected with a subcutaneous external chemotherapy bag, and the subcutaneous external chemotherapy bag It includes a base, a latex skin, a fixed cover and a protruding connection port. The base is in the shape of a disc, and the surrounding of the base disc is raised to form a wall. There is a screw mechanism, one side of the base wall is connected with a convex connection port, the fixed cover is in the shape of a ring, the upper part of the fixed cover is inclined inwardly and matches the top of the base, and the inner side of the lower part of the fixed cover is provided with internal thread, the latex skin is arranged between the base and the fixed cover, and the puncture drainage tube is connected with the external convex connection port. It can be drilled and punctured directly into the ventricle, and its end can be placed subcutaneously and closed, and can be repeatedly percutaneously punctured, and can be repeatedly punctured into the ventricle for administration without needing to puncture again.

Further, the head end of the puncture drainage tube is a closed blind cavity, the puncture drainage tube is provided with a drainage hole, the drainage hole is close to the head end of the drainage tube, and the tail end of the puncture drainage tube is an open cavity. It is convenient for intraventricular cerebrospinal fluid to enter the puncture drainage tube through the drainage hole.

Further, the top of the needle core is blunt and round, and a groove is opened near the top, and the needle core is provided with a shallow continuous groove at the lower end of the groove, and the lower end of the shallow continuous groove is close to the end of the needle core. After the puncture set is inserted into the ventricle, it is convenient to remove the needle core from the puncture drainage tube.

Further, the cranium fixation plate is cylindrical, the curved surface of the cranium fixation plate is connected with fixing wings, and the upper surface of the cranium fixation plate is provided with a slot. Fix the skull plate on the periosteum through the fixing wings, and fix the puncture and drainage tube.

Further, the inclination angle of the top of the enclosure wall of the base is 10-20°.

Through the above technical scheme, the beneficial effects of the utility model are:

The needle core of the utility model is placed in the lumen of the puncture drainage tube to form a puncture set, and the top of the needle core is punctured into the ventricle, and the cerebrospinal fluid will enter the groove of the needle core along the drainage tube hole and flow out along the shallow continuous groove, and the needle is pulled out Seeing that the cerebrospinal fluid flows out smoothly, the puncture and drainage tube is pierced through the round hole of the skull fixation plate, and the skull fixation plate and periosteum are fixed, and the puncture and drainage tube is stuck in the slot to form a fixation. The cavity of about 30mm*30mm is stretched and stripped under the aponeurosis, and the subcutaneous external chemotherapy capsule is placed in the cavity, and the end of the puncture drainage tube is connected with the convex connection port to complete the use process. The utility model can be directly placed by drilling and puncture. Into the ventricle, and its end can be placed subcutaneously closed, can be repeatedly percutaneously punctured, and can be repeatedly punctured into the ventricle without needing to be punctured again.

Description of drawings

Fig. 1 is a structural schematic diagram of a chemotherapy device of the present invention with a catheter placed in the ventricle and a subcutaneous chemotherapy capsule preset.

Fig. 2 is a schematic structural view of the puncture kit of the present invention.

Fig. 3 is a schematic structural view of the puncture drainage tube of the present invention.

Fig. 4 is a schematic structural view of the needle core of the present invention.

Fig. 5 is a schematic structural view of the skull fixing tray of the present invention.

Fig. 6 is a structural schematic diagram 1 of the subcutaneous external chemotherapy capsule of the present invention.

Fig. 7 is a schematic diagram 2 of the structure of the subcutaneous external chemotherapy capsule of the present invention.

The numbers in the drawings are: 1 is the puncture drainage tube, 101 is the drainage hole, 2 is the needle core, 201 is the groove, 202 is the shallow continuous groove, 3 is the skull fixing plate, 301 is the fixed wing, 302 is the card slot, 303 4 is a round hole, 4 is a subcutaneous external chemotherapy bag, 401 is a base, 402 is a latex skin, 403 is a fixed cover, and 404 is a convex connection port.

Detailed ways

Below in conjunction with accompanying drawing and specific embodiment the utility model is further described:

As shown in Figures 1 to 7, a chemotherapy device with subcutaneous catheterization in the ventricle and a subcutaneous chemotherapy bag, including a puncture drainage tube 1 and a needle core 2, the maximum diameter of the needle core 2 is equal to the inner diameter of the puncture drainage tube 1, and the length is longer than the puncture drainage tube 1. The length of the drainage tube 1, the puncture drainage tube 1 is provided with a skull fixing plate 3, the skull fixing plate 3 is provided with a drainage tube hole 303, and the puncture drainage tube 1 passes through the drainage tube hole 303, the The end of the puncture drainage tube 1 is connected with a subcutaneous external chemotherapy bag 4, and the subcutaneous external chemotherapy bag 4 includes a base 401, a latex skin 402, a fixed cover 403 and a convex connection port 404, and the base 401 is disc-shaped , the disc of the base 401 protrudes to form a surrounding wall, the top of the surrounding wall is in the shape of inner high and outer bottom, and the outer side is provided with a threaded mechanism, one side of the surrounding wall of the base 401 is connected to the outer convex connection port 404, and the fixed The cover 403 is in the shape of a ring, the upper part of the fixed cover 403 is inclined inwardly, and matches the top of the base 401, the inner side of the lower part of the fixed cover 403 is provided with internal threads, and the latex skin 402 is arranged between the base 401 and the fixed cover Between 403 , the puncture drainage tube 1 is connected to the external convex connection port 404 . The inclination angle of the top of the enclosure wall of the base 401 is 10-20°. The needle core 2 is placed in the lumen of the puncture drainage tube 1 to form a puncture set, which can puncture into the ventricle, and the latex skin 402 is placed between the base 401 and the fixed cover 403, and the base 401 and the fixed cover 403 are connected by threads Subcutaneous external chemotherapy capsule 4.

The head end of the puncture and drainage tube 1 is a closed blind cavity, the puncture and drainage tube 1 is provided with a drainage hole 101, the drainage hole 101 is close to the head end of the drainage tube 1, and the tail end of the puncture and drainage tube 1 is an open cavity. The top of the needle core 2 is blunt and circular, and a groove 201 is opened near the top. The needle core 2 is provided with a shallow continuous groove 202 at the lower end of the groove 201. end. The top of the needle core 2 extends into the puncture and drainage tube 1, and the end of the needle core 2 is located outside the puncture and drainage tube 1 to form a puncture kit. After the drainage hole 101 of 1 enters the ventricle, the cerebrospinal fluid will enter the groove 201 of the needle core along the drainage hole 101 and leak out of the distal end along the shallow continuous groove 202. When the needle core 2 is pulled out, it can be seen that the cerebrospinal fluid flows out smoothly.

The cranium fixation plate 3 is cylindrical, the curved surface of the cranium fixation plate 3 is connected with a fixation wing 301 , and the upper surface of the cranium fixation plate 3 is provided with a slot 302 . The skull fixing plate 3 is fixed on the periosteum through the fixing wings 301 , and the puncture and drainage tube 1 is stuck in the slot 302 for fixing.

When in use, the skull can be routinely drilled, with a diameter of about 20mm. The drilling point can be selected from the conventional ventricle puncture position, the dura can be burned to stop bleeding and cut, and the pia mater can be burned and cut at the puncture point; the top of the needle core 2 can be inserted into the puncture and drainage Inside the tube 1, the end of the needle core 2 is located outside the puncture and drainage tube 1 to form a puncture set. The puncture set directly punctures, and the top is blunt and round. The toughness and breakthrough feeling of breaking through the ventricular wall are obvious. , the cerebrospinal fluid will enter the groove 201 of the needle core along the drainage hole 101 and leak out of the distal end along the shallow continuous groove 202. Pull out the needle core 2, and it can be seen that the cerebrospinal fluid flows out smoothly. Pierce through the drainage tube hole 303 in the middle of the skull fixation tray 3, place the skull fixation tray 3 at the drilling hole in the skull, fix the skull fixation tray 3 on the periosteum through the fixation wings 301, and bend and squeeze the puncture drainage tube 1 into the card Fixation is formed in the groove 302, and the latex skin 402 is placed between the base 401 and the fixed cover 403. The base 401 and the fixed cover 403 are connected by threads to form a subcutaneous external chemotherapy bag 4. The subaponeurosis is stretched and stripped to a cavity of about 30mm*30mm, and the subcutaneous external chemotherapy capsule 4 is placed in the cavity, and the convex connection port 404 is connected to the end of the puncture drainage tube 1, and the galeal aponeurosis and the scalp are sutured.

After the surgical incision is removed, the subcutaneous external chemotherapy capsule 4 can be routinely used repeatedly. Before use, the local scalp endothelium is disinfected, because the base has a certain thickness and a round protrusion, which can be touched outside the skin and clearly positioned. The puncture needle is directly inserted into the skin Puncture in the groove of the base 401 under the latex skin 402, suction inspection can take out the cerebrospinal fluid in the ventricle as the lumen position and patency inspection, if necessary, a certain amount of cerebrospinal fluid can be taken out for decompression and cerebrospinal fluid inspection, conventional venous pump pumps chemotherapy drugs in In the chemotherapy capsule, the drug can directly enter the cerebroventricular system through this system, and quickly and evenly enter each ventricular system and brain surface under the action of the cerebrospinal fluid circulation to achieve therapeutic effects.

The above-described embodiments are only preferred embodiments of the utility model, and do not limit the scope of implementation of the utility model, so all equivalent changes or modifications made according to the technical solutions described in the patent scope of the utility model should be included in The utility model is within the scope of the patent application.

Claims (5)

1. A chemotherapy device for subcutaneous preset chemotherapy sac of ventricular catheter, which comprises a puncture drainage tube (1) and a needle core (2), it is characterized in that the maximum diameter of the needle core (2) is equal to the inner diameter of the puncture drainage tube (1), and the length is larger than the length of the puncture drainage tube (1), a skull fixing disk (3) is arranged on the puncture drainage tube (1), a drainage tube hole (303) is arranged on the skull fixing disk (3), the puncture drainage tube (1) passes through the drainage tube hole (303), the tail end of the puncture drainage tube (1) is connected with a subcutaneous external chemotherapy sac (4), the subcutaneous external chemotherapy capsule (4) comprises a base (401), a latex skin (402), a fixed cover (403) and an external convex connecting port (404), the base (401) is in a disc shape, the periphery of the disc of the base (401) is raised to form a wall, the top of the enclosing wall is in an inner-high outer-bottom shape, the outer side of the enclosing wall is provided with a screw thread mechanism, one side of the enclosing wall of the base (401) is connected with an outer convex connecting port (404), the fixing cover (403) is annular, the upper part of the fixing cover (403) inclines inwards, and is matched with the top of the base (401), the inner side of the lower part of the fixed cover (403) is provided with internal threads, the latex skin (402) is arranged between the base (401) and the fixed cover (403), the puncture drainage tube (1) is connected with an outer convex connecting port (404).

2. The chemotherapy device for the subcutaneous preset chemotherapy sac for the ventricular catheterization of the claim 1, wherein the head end of the puncture drainage tube (1) is a closed blind cavity, the puncture drainage tube (1) is provided with a drainage hole (101), the drainage hole (101) is close to the head end of the drainage tube (1), and the tail end of the puncture drainage tube (1) is an open cavity.

3. The chemotherapy device for the subcutaneous preset chemotherapy bag of the ventricular catheterization of claim 1, characterized in that the top end of the needle core (2) is blunt round and is provided with a groove (201) near the top end, the needle core (2) is provided with a shallow continuous groove (202) at the lower end of the groove (201), and the lower end of the shallow continuous groove (202) is near the tail end of the needle core (2).

4. The chemotherapy device for the subcutaneous preset chemotherapy bag of the ventricular catheterization of claim 1, wherein the skull fixing disk (3) is cylindrical, the curved surface of the skull fixing disk (3) is connected with fixing wings (301), and the upper surface of the skull fixing disk (3) is provided with a clamping groove (302).

5. The chemotherapy device for the subcutaneous preset chemotherapy bag for the ventricle of the brain according to claim 1, wherein the top of the enclosing wall of the base (401) has an inclination angle of 10-20 °.

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