CN218684493U - A sampling device for human body secretions - Google Patents

Abstract

The utility model relates to a sampling device for human body secretions, which belongs to the technical field of sampling devices. Including the pipe body; one end of the pipe body is provided with a nozzle, and the other end is closed; the inside of the pipe body is provided with a cavity one; the diameter of the cavity one is smaller than the nozzle, and the cavity one is transitionally connected with the nozzle; a cavity is provided below the cavity one 2. The diameter of the cavity 2 is smaller than the diameter of the cavity 1; the cavity 2 is transitionally connected with the cavity 1. The sampling device of the utility model can be used for operations such as sampling, centrifugation, and sample storage at the same time, and is convenient to use. The two-stage cavity can effectively separate the impurities and the supernatant after the sample is centrifuged, avoiding the impurity when the pipette tip is sampled in the device, and avoiding the subsequent detection of biomarkers in nipple discharge or other body fluids The impact of time impurities on observation.

Description

A sampling device for human body secretions

technical field

The utility model relates to the technical field of sampling devices, in particular to a sampling device for human body secretions.

Background technique

Nipple discharge is a common complaint of outpatients in breast surgery, and patients with nipple discharge can account for 1/10 to 1/20 of breast surgery outpatients on average. When a patient has nipple discharge, there is a 5%-8% chance of breast cancer. At present, the non-invasive examination methods of nipple discharge mainly include nipple discharge exfoliation cytology or liquid-based cytology examination and nipple discharge tumor marker examination. Smear or liquid-based cytology examination of discharge to detect exfoliated cancer cells is the most direct qualitative diagnosis of the cause of nipple discharge. The current sampling method for nipple discharge is to use a special glass slide to dip the nipple discharge, and then make a section for observation. Or collect nipple discharge and add cell preservation solution for subsequent centrifugation for observation, but there are the following problems: (1) the amount of dipping is small, and it is easy to fail to make slices; (2) it is inconvenient to store samples because of dipping and sampling . Nipple discharge tumor marker examination is currently the most effective laboratory test for differentiating benign and malignant nipple discharge. The detection process is generally to use a centrifuge tube to collect nipple discharge, and after centrifugation, take 10-20 μL of the supernatant to detect tumors on the computer. landmark. However, there are the following problems: (1) The inner diameter of the traditional centrifuge tube is too large, and it is easy to mistake the sediment at the bottom of the tube when absorbing the supernatant after centrifugation, and the impurities in it will easily affect the stability of the test results; (2) The design of the mouth of the traditional centrifuge tube is relatively poor Sharp, scraping nipple discharge specimens is easy to damage the skin of the nipple, and the design of the flat nozzle is more difficult to collect the discharge.

Utility model content

For the above-mentioned problems existing in existing nipple discharge sampling equipment, the utility model provides a sampling device for human body secretions to solve the above-mentioned problems. The external dimension of the sampling device of the utility model is the same as that of a commonly used 1.5mL centrifuge tube, and can be used for operations such as sampling, centrifugation, and sample preservation at the same time, and is convenient to use.

A sampling device for human secretions, comprising a tube body; one end of the tube body is provided with a nozzle, and the other end is closed; the inside of the tube body is provided with a cavity 1; the diameter of the cavity 1 is smaller than the nozzle, and the cavity 1 is connected to the tube The mouth is transitionally connected; the second cavity is provided below the first cavity; the diameter of the second cavity is smaller than the diameter of the first cavity; the second cavity is connected with the first cavity through a transition.

After sampling, human body secretions should be centrifuged. After centrifugation, impurities such as epidermal cells in the secretions will enter cavity 2, which can prevent impurities from being dipped in the device when sampling, and prevent impurities from affecting the observation after film production. Impact.

Further, the mouth of the nozzle is provided with a notch, and the notch is in the shape of a slope, which is convenient for sampling.

Further, the sampling device is also provided with a tube cover; the tube cover and the tube body are connected through a connecting part, and the connecting part is elastic; the tube cover is provided with a plug; To the role of the liquid in the sealed tube.

Further, the tube body and the tube cover are made of PE material.

Further, the first cavity is provided with a scale. The setting scale is easy to read the sample volume.

Further, the outer wall of the pipe body is provided with a frosted layer. The frosted layer is used to mark samples with an oil-based marker.

Further, the volume of the second cavity is 10-20 μL.

Further, the size of the tube body is consistent with the size of a 1.5mL centrifuge tube.

The working principle of the utility model is:

When sampling human body secretions, the nozzle of the sampling device is aligned with the overflow site, so that the liquid flows into the tube. The tubes are then capped tightly, and the device is placed in a centrifuge for centrifugation. Impurities after centrifugation will sink to the bottom, just take the supernatant when preparing smear samples. In the utility model, a cavity 2 with a smaller diameter is arranged at the lower part of the cavity 1 for storing centrifuged impurities, which can prevent impurities from being taken by mistake during sampling. After sampling, the sampling device can be stored in a liquid nitrogen tank for future use as a sample for clinical trials.

The beneficial effects of the utility model are:

The sampling device of the utility model can be used for operations such as sampling, centrifugation, and sample storage at the same time, and is convenient to use. The two-stage cavity can effectively separate the impurities and the supernatant after the sample is centrifuged, preventing the pipette tip from dipping into the impurities when sampling in the device, and avoiding the subsequent detection of biomarkers in nipple discharge or other body fluids The impact of time impurities on observation. The device of the utility model is used for the operation of collecting the supernatant when the suspension needs to be separated in the laboratory research work, for example: after cell culture, it is necessary to collect the exosomes in the supernatant, the application of the device of the utility model can better Fix the cells and sediment in the lower layer to avoid aspiration of the cell sediment when aspirating the supernatant.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the accompanying drawings that need to be used in the description of the embodiments or the prior art. Obviously, for those of ordinary skill in the art In other words, other drawings can also be obtained from these drawings under the premise of not paying creative work.

Fig. 1 is the structural representation of the utility model embodiment 2.

Fig. 2 is a cross-sectional view of the pipe body of Embodiment 2 of the present utility model.

In the figure, 1-pipe body, 2-pipe cap, 3-connecting part, 4-pipe mouth, 5-plug, 6-cavity one, 7-cavity two, 8-frosted layer, 9-notch.

Detailed ways

In order to enable those skilled in the art to better understand the technical solution in the utility model, the technical solution in the utility model embodiment will be clearly and completely described below in conjunction with the accompanying drawings in the utility model embodiment. Obviously, The described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present utility model, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

Example 1

A sampling device for human secretions, comprising a tube body 1; one end of the tube body 1 is provided with a nozzle 4, and the other end is closed; the inside of the tube body 1 is provided with a cavity-6; the diameter of the cavity-6 is smaller than the nozzle 4. Cavity 1 6 is transitionally connected with nozzle 4; the transition part is in the shape of a cone; cavity 2 7 is provided below cavity 1 6; the diameter of cavity 2 7 is smaller than that of cavity 1 6; cavity 2 7 It is transitionally connected with cavity one 6, and the transition part is in the shape of a truncated cone.

Example 2

A sampling device for human secretions, comprising a tube body 1; one end of the tube body 1 is provided with a nozzle 4, and the other end is closed; the inside of the tube body 1 is provided with a cavity-6; the diameter of the cavity-6 is smaller than the nozzle 4 , Cavity one 6 is transitionally connected with nozzle 4; Cavity one 6 is transitionally connected, and the transition part is frustum-shaped; cavity two 7 has a volume of 10 μL; the device is provided with a tube cover 2; tube cover 2 and tube body 1 are connected through a connecting part 3, and the connecting part 3 is elastic; The cover 2 is provided with a plug 5; the plug 5 can be inserted into the nozzle 4 to seal the liquid in the tube body; the nozzle is provided with a gap 9, and the gap 9 is slope-shaped; the cavity 6 is provided with a scale; the tube body The outer wall of 1 is provided with a frosted layer 8; the tube body 1 and the tube cover 2 are made of PE material; the size of the tube body 1 is consistent with that of a 1.5mL centrifuge tube.

Although the present utility model has been described in detail with reference to the accompanying drawings and in combination with preferred embodiments, the present utility model is not limited thereto. Without departing from the spirit and essence of the present utility model, those skilled in the art can make various equivalent modifications or replacements to the embodiments of the present utility model, and these modifications or replacements should all be within the scope of the present utility model Within the scope of the technology disclosed in the utility model, any person familiar with the technical field can easily think of changes or replacements, which should be covered within the protection scope of the utility model.

Claims (8)

1. A sampling device for human body secretions, characterized in that it comprises a tube body; one end of the tube body is provided with a spout, and the other end is closed; the inside of the tube body is provided with a cavity one; the diameter of the cavity one is smaller than the spout , Cavity 1 is transitionally connected to the nozzle; Cavity 2 is provided below Cavity 1; the diameter of Cavity 2 is smaller than that of Cavity 1; Cavity 2 is transitionally connected to Cavity 1. 2. A sampling device for human body secretions as claimed in claim 1, wherein the mouth of the nozzle is provided with a gap, and the gap is in the shape of a slope. 3. A sampling device for human secretions as claimed in claim 1, characterized in that the sampling device is also provided with a cap; the cap and the body are connected through a connecting portion; the cap is provided with a plug. 4. A sampling device for human body secretions as claimed in claim 3, wherein the tube body and the tube cover are made of PE material. 5. A sampling device for human body secretions as claimed in claim 1, characterized in that cavity one is provided with a scale. 6. A sampling device for human body secretions according to claim 1, characterized in that, the outer wall of the tube body is provided with a frosted layer. 7. A sampling device for human body secretions according to claim 1, wherein the volume of the second cavity is 10-20 μL. 8. A sampling device for human body secretions as claimed in claim 1, wherein the size of the tube body is consistent with the size of a 1.5mL centrifuge tube.

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