CN217297819U - Nucleic acid extraction apparatus - Google Patents
Nucleic acid extraction apparatus Download PDFInfo
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- CN217297819U CN217297819U CN202220941789.0U CN202220941789U CN217297819U CN 217297819 U CN217297819 U CN 217297819U CN 202220941789 U CN202220941789 U CN 202220941789U CN 217297819 U CN217297819 U CN 217297819U
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- nucleic acid
- air
- acid extraction
- extraction
- air inducing
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- 238000000605 extraction Methods 0.000 title claims abstract description 128
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 80
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 80
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 80
- 230000001939 inductive effect Effects 0.000 claims abstract description 47
- 238000001914 filtration Methods 0.000 claims description 31
- 230000006698 induction Effects 0.000 claims description 7
- 238000005070 sampling Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 description 8
- 239000000443 aerosol Substances 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 5
- 238000010438 heat treatment Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000003915 air pollution Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000005034 decoration Methods 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000009290 primary effect Effects 0.000 description 1
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Abstract
The utility model relates to the technical field of medical equipment, in particular to nucleic acid extraction equipment, which comprises a frame and a nucleic acid extraction working space; an independent extraction cabin is arranged in the nucleic acid extraction working space; a sample inlet and a first air inducing port are reserved in the extraction cabin; the first air inducing port is provided with a first air inducing device so as to form negative pressure in the extraction cabin; the nucleic acid extraction working space is provided with a second air inducing port which is provided with a second air inducing device so as to form negative pressure in the nucleic acid extraction working space; an extraction compartment air flow path is formed between the first induced draft opening and the second induced draft opening. The utility model relates to an ingenious, novel structure provides a new wind direction layout design for nucleic acid extraction equipment, has apparent popularization meaning.
Description
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to nucleic acid extraction equipment.
Background
Automatic nucleic acid extraction equipment of drawing can play important effect in epidemic situation prevention and control, and to nucleic acid extraction equipment, the accuracy of its nucleic acid extraction has fine requirement, current nucleic acid extraction equipment, because overall structure sets up unreasonablely, nucleic acid is through heating schizolysis/combination when drawing, washing, processes such as elution heating form aerosol easily, cause the pollution to test sample again easily after the aerosol loss, to a great extent has reduced nucleic acid testing's accuracy, additionally, the most that nucleic acid extraction equipment on the existing market used is HEPA module filtration system that the product was assembled, the inside air escape of instrument is realized to external entering machine inside, its device structure is complicated, difficult installation, still have defect with high costs.
Therefore, it is necessary to solve the above-mentioned technical problems.
SUMMERY OF THE UTILITY MODEL
To the technical problem, the utility model provides a nucleic acid extraction equipment through the redesign to the inside wind direction overall arrangement of instrument, has avoided producing biological aerosol and has polluted the nucleic acid sample, the utility model discloses a technical scheme as follows:
a nucleic acid extraction apparatus comprising:
a rack having a nucleic acid extraction work space;
an independent extraction cabin is arranged in the nucleic acid extraction working space;
a sample inlet and a first air inducing port are reserved in the extraction cabin; the first air inducing port is provided with a first air inducing device so as to form negative pressure in the extraction cabin;
the nucleic acid extraction working space is provided with a second air inducing port which is provided with a second air inducing device so as to form negative pressure in the nucleic acid extraction working space;
an extraction compartment air flow path is formed between the first induced draft opening and the second induced draft opening.
In some embodiments, the second air scoop is disposed at the top of the nucleic acid extraction workspace;
the bottom of the nucleic acid extraction working space is provided with a first working table;
the extraction cabin is arranged on the first working table surface;
the first air inducing opening is formed in the top of the extraction cabin.
In some embodiments, a second work surface is disposed above the extraction capsule;
the second working table surface is higher than the first working table surface;
and the second table top is provided with a manipulator and is used for sampling.
In some embodiments, an air filtering module is disposed at each of the first air inducing opening and the second air inducing opening.
In some embodiments, the air filtration module at the second air induction port is a high efficiency filtration module, and the air filtration module at the first air induction port is a primary filtration module.
In some embodiments, the air filtration module is secured by a filter screen mounting plate;
the air filtering module at the first air induction port is positioned inside the extraction cabin;
the air filtration module at the second air induction port is located inside the nucleic acid extraction work space.
In some embodiments, the first induced draft opening is provided in plurality;
each first induced air port is provided with one first induced air device.
In some embodiments, a plurality of the first induced draft holes share the same air filter module.
In some embodiments, the first air-inducing device is an axial fan.
In some embodiments, the second air-inducing device is a centrifugal fan.
Compared with the prior art, the utility model discloses the beneficial effect who has does:
1. the utility model provides a nucleic acid extraction equipment will draw the module and arrange the solitary under-deck that draws in to respectively set up an induced air device in drawing cabin and nucleic acid extraction working space, make the air by drawing the cabin outside to drawing the inside uniflow of cabin, and with nucleic acid extraction working space in other work modules not take place to interfere, greatly avoided the formation of biological aerosol and led to the fact the pollution to the nucleic acid sample, show the accuracy that has improved nucleic acid detection.
2. The utility model provides a nucleic acid draws equipment, with the second induced air mouth set up in nucleic acid draws workspace's top and first induced air mouth set up in draw the top in cabin, have good space utilization effect, draw the cabin air flow path simultaneously shorter, further avoid the formation of bioaerosol.
3. The utility model provides a nucleic acid draws equipment all is provided with the filtration module in first induced air mouth and second induced air mouth department, can filter the air that the air and nucleic acid that flow by drawing the cabin extracted the workspace and flow, avoids producing the air pollution around nucleic acid draws equipment, has good effect.
To sum up, the utility model relates to an ingenious, novel structure provides a new wind direction overall arrangement design for nucleic acid extraction equipment, has apparent popularization meaning.
Drawings
The invention will be described in further detail with reference to the following drawings and embodiments:
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of the structure of the extraction chamber of the present invention;
FIG. 3 is a schematic view of the cutting structure of the extraction chamber of the present invention;
FIG. 4 is a schematic diagram of the structure of the working space for nucleic acid extraction according to the present invention;
fig. 5 is a schematic view of the wind direction flow of the present invention;
the reference numbers illustrate:
the reference numbers illustrate: 100 is a nucleic acid extraction working space, 101 is a second air inducing device, 102 is a high-efficiency filtering module, 103 is a second air inducing port, and 104 is a first working table;
200 is an extraction cabin, 201 is a sample inlet, 202 is a first air inducing port, 203 is a first air inducing device, 204 is a primary effect filtering module, 205 is a second working table;
300 is a filter screen mounting plate;
400 is a gantry.
Detailed Description
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following description will refer to the accompanying drawings to describe specific embodiments of the present invention. It is obvious that the drawings in the following description are only examples of the invention, and that for a person skilled in the art, other drawings and embodiments can be derived from them without inventive effort.
For the sake of simplicity, only the parts related to the utility model are schematically shown in the drawings, and they do not represent the actual structure as a product. In addition, in order to make the drawings concise and understandable, components having the same structure or function in some of the drawings are only schematically illustrated or only labeled. In this document, "one" means not only "only one" but also a case of "more than one".
It should be further understood that the term "and/or" as used in this specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items and includes such combinations.
In this context, it is to be understood that, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In addition, in the description of the present application, the terms "first", "second", and the like are used only for distinguishing the description, and are not intended to indicate or imply relative importance.
Referring to fig. 1 to 5, the utility model provides a concrete structure of nucleic acid extraction equipment is elucidated, which comprises a frame 400, be provided with nucleic acid extraction workspace 100 in the frame 400, still be provided with solitary extraction cabin 200 in the nucleic acid extraction workspace 100 the extraction work of accomplishing nucleic acid in the extraction cabin 200, be provided with the consumptive material frame module that is used for nucleic acid extraction work in addition in the nucleic acid extraction workspace 100, move the liquid module, wherein consumptive material frame module is used for depositing the sample and consumptive material that await measuring, and extraction cabin 200 is provided with the work module and the reagent that nucleic acid extracted and amplify required heating schizolysis/combination, washing, elution heating etc. and sample in the liquid module can be delivered to the extraction module through artifical or mechanical mode to accomplish nucleic acid extraction.
The embodiment provides a new wind direction layout design, namely, a sample inlet 201 and a first air inducing port 202 are preset on the extraction chamber 200, wherein the sample inlet 201 is used for feeding and taking out a sample to be detected, the first air inducing port 202 is used for communicating the internal space of the extraction chamber 200 with the nucleic acid extraction working space 100, a first air inducing device 203 is arranged at the first air inducing port 202, and the first air inducing device 203 can drive the air in the extraction chamber 200 to be discharged so as to form negative pressure in the extraction chamber 200 and avoid forming bioaerosol in the extraction chamber 200.
Nucleic acid extraction workspace 100 is provided with second induced air mouth 103, second induced air mouth 103 department is provided with second induced air device 101 in order to form negative pressure in the nucleic acid extraction workspace 100, and the effect in second induced air mouth 103 lies in extracting the air in workspace 100 with nucleic acid and discharges to the frame 400 outside, and the air wherein includes the air of consumptive material frame module position, also includes the air in the extraction cabin 200 of first induced draft fan exhaust, and it is worth noting that in this embodiment first induced air mouth 202 with be formed with between the second induced air mouth 103 and draw cabin air flow path, avoid drawing the interior exhaust air pollution of cabin 200 and await measuring the sample and draw the sample.
The rack 400 structure provided by this embodiment can be set as a square box structure, the positions of the first induced air port 202 and the second induced air port 103 can be flexibly set according to the shapes of the first induced air device 203 and the second induced air device 101, when the nucleic acid extraction apparatus works, both the first induced air device 203 and the second induced air device 101 are activated, the first induced air device 203 discharges the air in the extraction compartment 200 to the nucleic acid extraction work space 100, a negative pressure is formed in the extraction compartment 200, formation of bioaerosol during the nucleic acid extraction process is avoided, due to formation of the negative pressure, a part of the air in the nucleic acid extraction work space 100 outside the extraction compartment 200 can also enter the extraction compartment 200 through the sample inlet 201, a unidirectional flow from the outside of the extraction compartment 200 to the inside of the extraction compartment 200 is formed, the discharged air in the extraction compartment 200 flows into the nucleic acid extraction work space 100 and is discharged to the outside of the rack 400 under the action of the second induced air device 101, air at other positions in the nucleic acid extraction work space 100 is also discharged outside the rack 400 under the action of the second air inducing device 101, so that the formation of bioaerosol and the pollution of a sample are effectively avoided, and the method has remarkable significance.
Specifically, in some embodiments, the second air induction port 103 is disposed at the top of the nucleic acid extraction workspace 100; the bottom of the nucleic acid extraction workspace 100 is provided with a first working platform 104, the consumable rack module, the extraction module and the extraction chamber 200 are all located on the first working platform 104, the sample inlet 201 is arranged on the side surface of the extraction chamber 200 and close to the consumable rack module, the first air inlet 202 is arranged on the top of the extraction chamber 200, in this embodiment, the consumable rack module, the extraction chamber 200 and the liquid-transfering module are located on the same working platform, and the second air inlet 103 is located above the structures, which can not only meet the high efficiency operation between the modules, but also shorten the air flow path of the extraction chamber, effectively reduce the risk of air escape polluting sample reagents, while in other embodiments, the consumable rack module, the extraction chamber 200 and the liquid-transfering module are located on the same working platform, but the first air inlet 202 can be arranged on the side wall of the extraction chamber 200 far away from the consumable rack module, the second induced air port 103 can also be disposed on the sidewall of the nucleic acid extraction working space 100, which has the same technical effect of avoiding aerosol generation as in the previous embodiment, but has a longer air flow path of the extraction chamber, and is set forth as a deformable embodiment in the present invention.
In some embodiments, the second working platform 205 is disposed above the extraction compartment 200, the second working platform 205 is disposed higher than the first working platform 104, and the manipulator is disposed on the second working platform 205 and used for sampling, the extraction compartment 200 provided in the present invention is disposed in the closed cavity of the first working platform 104, and has an outer surface, therefore, in some modified embodiments, the second working platform 205 can be formed by the top outer surface of the extraction compartment 200, the extraction compartment 200 can be used for closing the extraction work module therein, and the top outer surface thereof can also be used as the second working platform 205 and used for installing the manipulator, thereby achieving dual technical effects.
In some embodiments, the first air-introducing opening 202 and the second air-introducing opening 103 are both provided with an air filtering module for filtering biomolecules in air to avoid polluting air around the nucleic acid extraction device, further, the air filtering module located at the second air-introducing opening 103 can be set to be the high-efficiency filtering module 102 to have a high-efficiency air filtering effect, the air filtering module located at the first air-introducing opening 202 is the primary-efficiency filtering module 204, and a structure that the high-efficiency filtering module 102 is matched with the primary-efficiency filtering module 204 is adopted, so that on one hand, air in the extraction chamber 200 can be filtered secondarily to effectively improve the air filtering effect, on the other hand, the manufacturing cost can be reduced, and certain economic benefits are achieved.
In some embodiments, the air filter module is specifically configured to be secured by a filter mounting plate 300, and the filter mounting plate 300 has holes for air to pass through and may also be used to secure the air filter module. Preferably, the air filter module at the first air introduction port 202 is located inside the extraction chamber 200, and the air filter module at the second air introduction port 103 is located inside the nucleic acid extraction work space 100, so as to further reduce the risk of contaminating the space outside the rack 400, and in other embodiments, the first air introduction port 202 may be located outside the extraction chamber 200, or may be located inside and outside the first air introduction port 202, and the second air introduction port 103 may be located outside the nucleic acid extraction work space 100.
In some embodiments, the first air inducing openings 202 are provided in plural numbers, each of the first air inducing openings is provided with one first air inducing device 203, the plural first air inducing openings 202 may be uniformly distributed on the top of the extraction cabin 200, and may also be flexibly set according to the actual situation of the extraction cabin 200, so that the air in the extraction cabin 200 may be sufficiently discharged, the energy consumption of each first air inducing device 203 may also be reduced, and the cost may be saved. Specifically, the first air inducing device 203 may be configured as an axial fan, and the second air inducing device 101 may be configured as a centrifugal fan, and the axial fan has a more gathered air flowing direction than the centrifugal fan, is not easy to escape, and is suitable to be disposed inside the extraction compartment 200.
It should be noted that the above embodiments can be freely combined as necessary. The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the principle of the present invention, and these improvements and decorations should also be regarded as the protection scope of the present invention.
Claims (10)
1. A nucleic acid extraction apparatus, comprising:
a rack having a nucleic acid extraction work space;
an independent extraction cabin is arranged in the nucleic acid extraction working space;
a sample inlet and a first air inducing port are reserved in the extraction cabin; the first air inducing port is provided with a first air inducing device so as to form negative pressure in the extraction cabin;
the nucleic acid extraction working space is provided with a second air inducing port which is provided with a second air inducing device so as to form negative pressure in the nucleic acid extraction working space;
an extraction compartment air flow path is formed between the first induced draft opening and the second induced draft opening.
2. The nucleic acid extraction apparatus according to claim 1,
the second air inducing port is arranged at the top of the nucleic acid extracting work space;
the bottom of the nucleic acid extraction working space is provided with a first working table;
the extraction cabin is arranged on the first working table surface;
the first air inducing opening is arranged at the top of the extraction cabin.
3. The nucleic acid extraction apparatus according to claim 2,
a second working table is arranged above the extraction cabin;
the second working table surface is higher than the first working table surface;
and the second working table surface is provided with a manipulator and is used for sampling.
4. The nucleic acid extraction apparatus according to any one of claims 1 to 3,
and air filtering modules are arranged at the first air inducing port and the second air inducing port.
5. The nucleic acid extraction apparatus according to claim 4,
the air filtering module at the second air inducing opening is a high-efficiency filtering module, and the air filtering module at the first air inducing opening is a primary filtering module.
6. The nucleic acid extraction apparatus according to claim 4,
the air filtering module is fixed through a filter screen mounting plate;
the air filtering module at the first air induction port is positioned inside the extraction cabin;
the air filtration module at the second air induction port is located inside the nucleic acid extraction work space.
7. The nucleic acid extraction apparatus according to claim 4,
a plurality of first air inducing openings are arranged;
each first induced air port is provided with one first induced air device.
8. The nucleic acid extraction apparatus according to claim 7,
the first air inducing openings share the same air filtering module.
9. The nucleic acid extraction apparatus according to claim 1,
the first air inducing device is an axial flow fan.
10. The nucleic acid extraction apparatus according to claim 1,
the second air inducing device is a centrifugal fan.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220941789.0U CN217297819U (en) | 2022-04-22 | 2022-04-22 | Nucleic acid extraction apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220941789.0U CN217297819U (en) | 2022-04-22 | 2022-04-22 | Nucleic acid extraction apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217297819U true CN217297819U (en) | 2022-08-26 |
Family
ID=82915153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202220941789.0U Active CN217297819U (en) | 2022-04-22 | 2022-04-22 | Nucleic acid extraction apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217297819U (en) |
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2022
- 2022-04-22 CN CN202220941789.0U patent/CN217297819U/en active Active
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