CN216725523U - A transcutaneous electrical stimulation blood sugar control device - Google Patents

Abstract

A blood sugar control device for transcutaneous electrical stimulation, comprising: a host, and an abdominal electrode sheet magnetically attracted by the host; the abdominal electrode sheet, comprising: a conductive adhesive layer for adhering to the skin and conducting electricity and a solid magnetic conductor for magnetically attracting the magnetic interface; after the host and the abdominal electrode sheet are combined by magnetic attraction, the abdominal electrode sheet is adhered to the skin of the small intestine region of the human body; the host includes: a casing and an electrical stimulation generating unit accommodated in the casing, wherein the electrical stimulation occurs The unit includes: a main control circuit and a communication unit electrically connected to the main control circuit, a stimulation current amplifying unit, and an abdominal electrode patch monitoring circuit; the abdominal electrode patch monitoring circuit is connected to the stimulation current amplifying unit and a solid-state magnetic conductor. The utility model does not require surgery, the stimulation position and the electric stimulation scheme can be adjusted, the safety is higher, and the cost is low.

Description

A transcutaneous electrical stimulation blood sugar control device

technical field

The utility model belongs to the technical field of medical devices, in particular to a transcutaneous electrical stimulation blood sugar control device.

Background technique

Diabetes mellitus (DM) is a metabolic disease, which is mainly caused by absolute or relative lack of insulin secretion, accompanied by a decrease in the body's sensitivity to insulin, resulting in elevated blood sugar and dyslipidemia. Because it is often accompanied by damage to blood vessels, peripheral nerves and organs, it has a high disability and fatality rate, and is second only to cancer in the degree of harm to the human body. More than 90% of diabetes is type 2 diabetes (T2DM). The treatment of T2DM currently mainly includes three aspects, lifestyle intervention, drug treatment, and surgical treatment. Simple lifestyle intervention is difficult to maintain long-term blood sugar stability, and drug treatment has side effects such as low blood sugar control rate, gastrointestinal discomfort, organ damage, hypoglycemia, and weight gain. Intestinal Electrical Stimulation (IES), especially the small intestine electrical stimulation, is a novel neuromodulation method.

On the one hand, IES has effects similar to electrical bypass surgery: it can delay gastric emptying, reduce food intake and nutrient absorption, inhibit ghrelin and increase glucagon-like peptide-1 (GLP-1) release . GLP-1 is a neuropeptide secreted by L cells in the lower part of the small intestine in a nutrient-dependent manner. The "incretin effect" produced by GLP-1 accounts for more than 50% of postprandial insulin secretion, and mainly regulates blood glucose homeostasis by changing insulin secretion. It also affects glucose transport in a pancreas-independent manner. The importance of GLP-1 in blood sugar regulation has been confirmed by many basic clinical studies and used in the treatment of type 2 diabetes. In vivo studies demonstrated that electrical stimulation enhanced GLP-1 secretion, whereas direct electrical stimulation of isolated distal ileal intestinal segments in vitro enhanced nutrient-induced GLP-1 secretion. In addition, IES can accelerate gastrointestinal motility, promote the rapid delivery of nutrients to the lower part of the small intestine, contact with the intestinal mucosa earlier, and stimulate the rapid release of GLP-1 from L cells in the lower part of the small intestine, thereby exerting incretin hypoglycemic effects. On the other hand, existing studies have shown that exercise can promote skeletal muscle cell transport and use of glucose to improve insulin resistance, thereby alleviating and reversing the progression of type 2 diabetes. Exercise can activate the glucose transporter 4 (glucose transporter 4, GLUT4) in skeletal muscle cells, increase the expression of GLUT4 in skeletal muscle cells and translocate to the cell membrane, thereby promoting the uptake of glucose by skeletal muscle. Electrical stimulation is the use of pulsed current to induce muscle contraction by stimulating nerves and muscles, which can achieve similar effects to active skeletal muscle contraction.

In addition, electrical stimulation can promote local blood circulation; after stimulating neurons (especially sensory nerves), they release a small amount of substances such as substance P and acetylcholine, causing vasodilation response; muscles produce rhythmic contractions, and their metabolism after activity Substances such as lactic acid, ADP, ATP, etc. have a strong vasodilator effect, which can improve the blood supply of muscle tissue.

Therefore, electrical stimulation acts on the surface of the body, by improving blood supply to muscle tissue, changing gastrointestinal motility, affecting gastrointestinal hormone secretion, increasing the body's insulin sensitivity, improving insulin resistance, and reducing blood sugar, and intestinal electrical stimulation mainly improves early-phase insulin secretion. , does not increase biphasic insulin secretion, does not produce hyperinsulinemia, and reduces the risk of hypoglycemia before the next meal.

In the prior art, the medium frequency rehabilitation therapy device is a common electrical stimulation physiotherapy device, which has the functions of analgesia, promoting local blood circulation, exercising muscles, softening scars, loosening adhesions, and reducing inflammation. Inflammation, low back myofascitis, cervical spondylosis, lumbar spondylosis, osteoarthritis and other diseases. Patent document CN205084220U discloses bionic electrical stimulation therapy, which is a commonly used clinical rehabilitation therapy. According to the frequency of the stimulation current, it can be divided into three types: low frequency (less than 1000Hz), medium frequency (1000Hz-100KHz), and high frequency (greater than 100KHz). At present, the intermediate frequency rehabilitation therapy instruments on the market can be divided into fixed and portable according to the form of equipment use; the fixed intermediate frequency rehabilitation therapy instruments mostly use inefficient class AB power amplifiers, but their power consumption is large, the heat sink is required, and the whole machine is bulky. It is not convenient for users to carry around; the volume and weight of the portable intermediate frequency rehabilitation therapy instrument are still too large, and the connection method with the abdominal electrode pads basically requires the participation of wires, and the whole machine cannot be directly applied to the affected area to achieve a wearable effect. Implantable sacral nerve electrical stimulation therapy equipment needs to be surgically implanted into the human body, which is expensive and has many adverse reactions. Once the stimulation reflex area is changed or incorrect, it needs to be re-implanted or even the operation fails.

SUMMARY OF THE INVENTION

The technical problem to be solved by the present invention is to provide a blood sugar control device for wearable electrical stimulation that can be directly applied to the affected area.

The utility model is realized in this way:

A transcutaneous electrical stimulation blood sugar control device, comprising: a host, and an abdominal electrode sheet magnetically attracted by the host;

The abdominal electrode sheet includes: a conductive adhesive layer for adhering to the skin and conducting electricity and a magnetic interface for magnetically attracting a solid-state magnetic conductor;

After the host and the abdominal electrode sheet are combined by magnetic attraction, the abdominal electrode sheet is adhered to the skin of the small intestine region of the human body;

The host includes: a casing and an electrical stimulation generating unit accommodated in the casing, wherein the electrical stimulation generating unit includes: a main control circuit and a communication unit electrically connected to the main control circuit, a stimulation current amplification a unit, an abdominal electrode patch monitoring circuit; the abdominal electrode patch monitoring circuit is connected to the stimulation current amplifying unit and the solid-state magnetic conductor;

The surface of the casing is provided with: an interface for connecting the solid magnetic conductor and a communication interface for connecting the communication unit.

Further, the main control circuit includes: MCU, charging and communication interface, lithium-ion charging circuit, power management circuit, boost circuit, current detection circuit, stimulation generator, stimulation current output interface, overcurrent protection circuit, open circuit Detection circuit, communication interface chip, buttons, indicator lights, sampling logic generator, sampling and holding circuit; the MCU is respectively connected to the power management circuit, the boost circuit, the overcurrent protection circuit, and the open circuit detection circuit , the sampling logic generator, the communication interface chip, the button, and the indicator light; the lithium-ion charging circuit is respectively connected to the power management circuit and the charging and communication interface; the communication interface chip is also connected to the charging and communication interfaces; the current detection circuit is respectively connected to the boost circuit, the sampling and holding circuit, and the stimulation generator; the sampling and holding circuit is also connected to the overcurrent protection circuit, the an open circuit detection circuit and the sampling logic generator; the stimulation generator is also connected to the stimulation current output interface.

Further, the intermediate frequency frequency is continuously adjustable at 0-20kHz, and the low frequency frequency is continuously adjustable at 0-200Hz;

Further, the host further includes: a charging circuit connecting the charging connector and a rechargeable internal power source, wherein the rechargeable internal power source includes a lithium battery with a battery protection circuit.

Further, the housing is formed by plastic molding or metal processing, and the total volume of the housing is less than 50 cubic centimeters; the solid magnetic conductor is made of NdFeB material, and its thickness is not more than 8 mm.

Further, the communication unit includes: Bluetooth or WIFI.

Further, the host computer is also connected to a host computer, and the host computer includes a mobile phone, a tablet computer, other personal terminals or a cloud server.

Further, a current with a frequency of 2-50 Hz can be selected for electrical stimulation.

The utility model has the advantages that no operation is required, the stimulation position and the electric stimulation scheme can be adjusted, the safety is higher, and the cost is low. It has the function of monitoring the falling off of abdominal electrode pads to prevent accidental safety risks.

Description of drawings

The present utility model will be further described below with reference to the accompanying drawings and embodiments.

FIG. 1 is a schematic structural diagram of an embodiment of the present invention.

FIG. 2 is a schematic block diagram of a main control circuit in an embodiment of the present invention.

Detailed ways

As shown in FIG. 1 , a transcutaneous electrical stimulation blood sugar control device includes: a host 1 , and an abdominal electrode sheet 2 magnetically attracted by the host 1 . The abdominal electrode sheet 2 includes: a conductive adhesive layer for adhering to the skin and conducting electricity and a magnetic interface for magnetically attracting a solid magnetic conductor. After the host 1 and the abdominal electrode sheet 2 are combined by magnetic attraction, the abdominal electrode sheet 2 is adhered to the skin of the small intestine region of the human body.

The host 1 includes: a casing 11 and an electrical stimulation generating unit accommodated in the casing 11, wherein the electrical stimulation generating unit includes: a main control circuit 12, a communication unit 13 electrically connected to the main control circuit 12, a stimulation current amplification Unit 14, abdominal electrode pad monitoring circuit 15; the abdominal electrode pad monitoring circuit 15 is connected to the stimulation current amplifying unit 14 and a solid-state magnetic conductor.

The surface of the casing 11 is provided with: an interface for connecting the solid magnetic conductor and a communication interface for connecting the communication unit 13 .

As shown in FIG. 2 , the main control circuit 12 includes: MCU, charging and communication interface, lithium-ion charging circuit, power management circuit, boost circuit, current detection circuit, stimulation generator, stimulation current output interface, and overcurrent protection circuit , open circuit detection circuit, communication interface chip, button, indicator light, sampling logic generator, sample and hold circuit; the MCU is respectively connected to the power management circuit, the boost circuit, the overcurrent protection circuit, the open circuit detection circuit, the sampling logic generator, the communication interface chip (485 communication in this embodiment), the button, and the indicator light; the lithium ion charging circuit is respectively connected to the power management circuit and the charging and communication interface; the communication interface chip is also connected to the charging and communication interface; the current detection circuit is respectively connected to the boost circuit, the sampling and holding circuit, and the stimulation generator; the sampling and holding circuit also The overcurrent protection circuit, the open circuit detection circuit, and the sampling logic generator are respectively connected; the stimulation generator is also connected to the stimulation current output interface.

Among them, the charging and communication interface uses a non-exposed blade battery charging interface;

Lithium-ion charging circuit to achieve rechargeable function;

Power management circuit, realizes functions such as battery low voltage protection, real-time clock power supply, battery hardware overcurrent protection, etc.;

Boost circuit, realize single-cell lithium battery voltage program-controlled boost function;

Current detection circuit to monitor battery output current;

The stimulation generator uses the MOS tube array and the related control circuit to modulate the low-frequency waveform to the intermediate-frequency electrical pulse;

Stimulation current output interface: use the magnetic buckle as the stimulation current output interface;

Overcurrent protection circuit: It is used to prevent the short circuit of the stimulation output circuit from causing damage to the internal circuit. If overcurrent occurs, the stimulation output will be stopped, and the buzzer will sound an alarm;

Open circuit detection circuit: It is used to detect the connection state between the stimulation output electrode and the human body. If there is an open circuit, the output will stop, and the buzzer will sound an alarm;

内核CPUMCU (main control chip): STM32 ultra-low power consumption, the highest performance

Kernel CPU

Keys: including power key, emergency stop key, and stimulation intensity adjustment key.

Indicator light: including working status indicator, battery status indicator, stimulation output intensity indicator, fault indicator.

The host 1 is also connected to a host computer, and the host computer includes a mobile phone, a tablet computer, other personal terminals or a cloud server. The upper computer is used to manage the blood glucose control device.

In use, the intermediate frequency frequency is continuously adjustable at 0-20 kHz, and the low-frequency frequency is continuously adjustable at 0-200 Hz; preferably, a current with a frequency of 2-50 Hz can be selected for electrical stimulation.

The abdominal electrode sheet 2 with a magnetic connector has the function of adhering to the skin of the small intestine area. After attracting and connecting with the solid magnetic conductor on the main unit 1, the main unit 1 can be fixed, so that the main unit 1 and the abdominal electrode sheet 2 can be combined and adhered to the skin to achieve Wearable functionality. The host 1 contains an abdominal electrode monitoring circuit to monitor the loop resistance. Once the abdominal electrode falls off the human body and the loop resistance is too large, the main control unit immediately interrupts or terminates the current output to ensure safety.

The utility model has the advantages of compact structure, small volume, light weight, convenient operation, low cost, safety and reliability.

Claims (8)

1. A transcutaneous electro-stimulation glycemic control device, characterized by: the method comprises the following steps: the main machine and the abdomen electrode plate magnetically attracted by the main machine;

the abdomen electrode slice includes: the conductive adhesive layer is used for adhering skin to conduct electricity, and the magnetic interface is used for magnetically attracting the solid magnetic conductor;

after the host machine and the abdomen electrode slice are combined through magnetic attraction, the abdomen electrode slice is adhered to the skin of the small intestine area of the human body;

the host, comprising: the electrical stimulation generating device comprises a shell and an electrical stimulation generating unit accommodated in the shell, wherein the electrical stimulation generating unit comprises: the device comprises a main control circuit, and a communication unit, a stimulation current amplification unit and an abdomen electrode plate monitoring circuit which are electrically connected with the main control circuit; the abdominal electrode slice monitoring circuit is connected with the stimulating current amplifying unit and the solid magnetic conductor;

the housing, on a surface thereof: an interface for connecting the solid magnetic conductor and a communication interface for connecting the communication unit.

2. The transcutaneous electro-stimulation glucose control device of claim 1, wherein:

the master control circuit comprises: the device comprises an MCU (microprogrammed control Unit), a charging and communication interface, a lithium ion charging circuit, a power management circuit, a booster circuit, a current detection circuit, a stimulus generator, a stimulus current output interface, an overcurrent protection circuit, an open-circuit detection circuit, a communication interface chip, a key, an indicator lamp, a sampling logic generator and a sampling holding circuit; the MCU is respectively connected with the power management circuit, the booster circuit, the overcurrent protection circuit, the open circuit detection circuit, the sampling logic generator, the communication interface chip, the key and the indicator light; the lithium ion charging circuit is respectively connected with the power management circuit and the charging and communication interface; the communication interface chip is also connected with the charging and communication interface; the current detection circuit is respectively connected with the boosting circuit, the sampling and holding circuit and the stimulation generator; the sampling hold circuit is also respectively connected with the overcurrent protection circuit, the open-circuit detection circuit and the sampling logic generator; the stimulation generator is also connected with the stimulation current output interface.

3. A transcutaneous electro-stimulation glucose control device as claimed in claim 1 or 2, wherein: the medium frequency is continuously adjustable at 0-20kHz, and the low frequency is continuously adjustable at 0-200 Hz.

4. A transcutaneous electro-stimulation glucose control device as claimed in claim 1 or 2, wherein: the host computer further comprises: and a charging circuit connecting the charging connector and a rechargeable internal power supply including a lithium battery with a battery protection circuit.

5. A transcutaneous electro-stimulation glucose control device as claimed in claim 1 or 2, wherein: the housing is formed by plastic molding or metal processing, and the total volume of the housing is less than 50 cubic centimeters; the solid magnetic conductor is made of neodymium iron boron materials, and the thickness of the solid magnetic conductor is not more than 8 mm.

6. A transcutaneous electro-stimulation glucose control device as claimed in claim 1 or 2, wherein: the communication unit includes: bluetooth or WIFI.

7. A transcutaneous electro-stimulation glucose control device as claimed in claim 1 or 2, wherein: the host is further connected with an upper computer, and the upper computer comprises a mobile phone, a tablet personal computer, other personal terminals or a cloud server.

8. A transcutaneous electro-stimulation glucose control device as claimed in claim 1 or 2, wherein: the current with the frequency of 2-50 Hz can be selected for electrical stimulation.

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