CN216315106U - Cooling device used in stem cell cryopreservation process - Google Patents
Cooling device used in stem cell cryopreservation process Download PDFInfo
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- CN216315106U CN216315106U CN202122110196.8U CN202122110196U CN216315106U CN 216315106 U CN216315106 U CN 216315106U CN 202122110196 U CN202122110196 U CN 202122110196U CN 216315106 U CN216315106 U CN 216315106U
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Abstract
The utility model discloses a cooling device used in a stem cell cryopreservation process, which comprises a tank body and a transmission mechanism, wherein a liquid nitrogen cavity is formed between an inner tank and the inner side wall of the tank body, a transmission cavity is formed in the bottom of the tank body, the transmission mechanism is arranged on the inner side wall of the transmission cavity, the transmission mechanism comprises a driven wheel, a driven rod, a speed reducing motor, a transmission rod and a transmission wheel, the driven wheel is arranged on the inner side wall of the transmission cavity, the surface of the driven wheel is provided with the driven rod, one end of the driven rod extends into the inner tank, the bottom of the tank body is provided with the speed reducing motor, the power output end of the speed reducing motor is fixedly connected with transmission, one end of the transmission rod extends into the transmission cavity, one end of the transmission rod is provided with the transmission wheel, and the transmission wheel is meshed with the driven wheel. According to the utility model, the mixing efficiency of the stem cells and the frozen stock solution is accelerated through the rotation of the test tube, so that the stem cells and the frozen stock solution can be rapidly mixed, and the stem cells are prevented from breaking and dying in the cooling process.
Description
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a cooling device used in a stem cell cryopreservation process.
Background
Stem cells are blast cells having division potential and self-renewal ability, which are present in tissues such as embryonic or adult brain, spinal cord, etc., and can be differentiated into various types of cells of nerve tissues such as neurons, astrocytes, oligodendrocytes, etc., through unequal division, and can also be trans-differentiated into blood cells and skeletal muscle cells. The current scientific technology can be used for culturing and amplifying the neural stem cells in vitro, and the neural stem cells are generally in a suspension state, do not adhere to the wall and have the characteristic of forming neurospheres in the in vitro culture process. The neural stem cells cultured in vitro can be used in the fields of life science research, drug screening test, clinical application research and the like.
Patent number CN211575644U discloses a heat sink that stem cell cryopreserved in-process used, the heat sink that stem cell cryopreserved in-process used includes box, upper cover, handle and hasp, the box top is rotated through the hinge and is connected with the upper cover, there is the handle upper cover top through pivot swing joint, the hasp is all installed to box and upper cover lateral wall. According to the utility model, cold air can be released when liquid nitrogen in the cooling pool absorbs heat, the top of the other end of the liquid storage tank is connected with the sewer pipe, the other end of the sewer pipe is connected with the liquid storage tank, so that a circulating pipeline can be formed, the cooling storage effect on stem cells can be effectively improved by circulating the liquid nitrogen, and the temperature sensor and the temperature display are matched with each other, so that the temperature in the accommodating groove can be measured and displayed, therefore, a user can monitor the storage temperature of each group of stored stem cells more conveniently and more conveniently.
The cooling device used in the existing stem cell cryopreservation process has the following disadvantages: 1. the slow mixing of the stem cells and the frozen stock solution in the cooling process is likely to cause the stem cells to break and die, thereby causing unnecessary economic loss. Therefore, a cooling device used in the stem cell cryopreservation process is provided.
SUMMERY OF THE UTILITY MODEL
The utility model mainly aims to provide a cooling device used in a stem cell cryopreservation process, which can effectively solve the problems in the background technology.
In order to achieve the purpose, the utility model adopts the technical scheme that:
the utility model provides a heat sink that stem cell cryopreserved in-process used, includes a jar body and drive mechanism, jar body bottom fixedly connected with supporting leg, the internal portion of jar has seted up the inner tank, the liquid nitrogen chamber has been seted up between inner tank and the internal lateral wall of jar, the transmission chamber has been seted up to jar body bottom, drive mechanism is installed to transmission intracavity lateral wall, drive mechanism is including following driving wheel, driven lever, gear motor, transfer line and drive wheel, the driven wheel is installed to transmission intracavity lateral wall, driven wheel surface mounting has the driven lever and driven lever one end extends to the inner tank in, gear motor is installed to jar body bottom, gear motor power take off end fixedly connected with transmission and transfer line one end extend to the transmission intracavity, drive wheel and drive wheel are installed to transfer line one end and are linked to each other with from the meshing of driving wheel.
Furthermore, a test tube tray is fixedly connected to the top end of the driven rod, and test tube grooves which are uniformly arranged are formed in the surface of the test tube tray; the test tube is placed to the test tube groove on the accessible test tube board, is convenient for put into jar internal with the test tube, and test tube fixed operation is simple convenient, and operating efficiency is high.
Further, a sealing cover is mounted at the top end of the tank body, and a handle is fixedly connected to the surface of the sealing cover; the sealed lid of accessible seals up the jar body, ensures jar body seal nature, and the accessible handle is carried the jar body and is removed for jar body portable increases the device flexibility.
Furthermore, the side wall of the tank body is communicated with a liquid inlet pipe and a liquid outlet pipe, one ends of the liquid inlet pipe and the liquid outlet pipe extend into the liquid nitrogen cavity, and stop valves are arranged on the surfaces of the liquid inlet pipe and the liquid outlet pipe; accessible feed liquor pipe lets in the liquid nitrogen to the liquid nitrogen intracavity, and accessible drain pipe discharge liquid nitrogen opens and shuts through stop valve control feed liquor pipe and drain pipe.
Further, a controller is installed on the surface of the tank body, and the speed reducing motor is electrically connected with an external power supply through the controller; the speed reduction motor can be controlled to operate through the controller, the operation is simple and convenient, a power supply is not required, and the manufacturing cost is saved.
Compared with the prior art, the utility model has the following beneficial effects: 1. open a jar body through sealed lid, put into the test tube inslot with the test tube, through sealed lid sealed jar body, let in the liquid nitrogen to the liquid nitrogen intracavity through the feed liquor pipe, cool down the inner tank through the liquid nitrogen, accessible controller control gear motor operation, gear motor power take off end rotates and drives the transfer line and rotates, the transfer line rotates and drives the drive wheel rotation, the drive wheel rotates and drives rather than the driven rotation of driving wheel meshing, it rotates to drive the follower lever from the driven rotation of driving wheel, the follower lever rotating band drives the test tube plate and rotates, the test tube plate rotates the test tube that drives the test tube inslot and rotates, the mixing efficiency of dry cell and frozen stock liquid is accelerated through the test tube rotation, guarantee dry cell can the flash mixed with frozen stock liquid, prevent that the dry cell from breaking death at the cooling in-process.
Drawings
Fig. 1 is a schematic view of the overall structure of a cooling device used in the stem cell cryopreservation process of the present invention.
Fig. 2 is a schematic diagram of the internal structure of a cooling device used in the stem cell cryopreservation process according to the present invention.
Fig. 3 is a partially enlarged structural schematic diagram of a temperature reducing device used in the stem cell cryopreservation process in fig. 2.
In the figure: 1. a tank body; 2. supporting legs; 3. a controller; 4. a transmission mechanism; 41. a driven wheel; 42. a driven lever; 43. a reduction motor; 44. a transmission rod; 45. a driving wheel; 5. a liquid inlet pipe; 6. a liquid outlet pipe; 7. a stop valve; 8. a sealing cover; 9. a handle; 10. a transmission cavity; 11. a liquid nitrogen cavity; 12. an inner tank; 13. a test tube tray; 14. a test tube groove.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the utility model easy to understand, the utility model is further described with the specific embodiments.
As shown in fig. 1-3, a cooling device used in a stem cell cryopreservation process comprises a tank body 1 and a transmission mechanism 4, wherein the bottom of the tank body 1 is fixedly connected with a support leg 2, an inner tank 12 is arranged inside the tank body 1, a liquid nitrogen cavity 11 is arranged between the inner tank 12 and the inner side wall of the tank body 1, the bottom of the tank body 1 is provided with a transmission cavity 10, the inner side wall of the transmission cavity 10 is provided with the transmission mechanism 4, the transmission mechanism 4 comprises a driven wheel 41, a driven rod 42, a speed reducing motor 43, a transmission rod 44 and a transmission wheel 45, the inner side wall of the transmission cavity 10 is provided with a driven wheel 41, the surface of the driven wheel 41 is provided with the driven rod 42, one end of the driven rod 42 extends into the inner tank 12, the bottom of the tank body 1 is provided with the speed reducing motor 43, the power output end of the speed reducing motor 43 is fixedly connected with transmission, and one end of the transmission rod 44 extends into the transmission cavity 10, one end of the transmission rod 44 is provided with a transmission wheel 45, and the transmission wheel 45 is meshed with the driven wheel 41.
The top end of the driven rod 42 is fixedly connected with a test tube disc 13, and test tube grooves 14 which are uniformly arranged are formed in the surface of the test tube disc 13; the test tube is placed to the test tube groove 14 on the accessible test tube board, is convenient for put into jar body 1 with the test tube in, and the fixed easy operation of test tube is convenient, and the operating efficiency is high.
The top end of the tank body 1 is provided with a sealing cover 8, and the surface of the sealing cover 8 is fixedly connected with a handle 9; the accessible is sealed 8 to jar body 1 and is sealed, the leakproofness of the guarantee jar body 1, and the accessible handle 9 is carried the jar body 1 and is removed for jar body 1 portable increases the device flexibility.
The side wall of the tank body 1 is communicated with a liquid inlet pipe 5 and a liquid outlet pipe 6, one ends of the liquid inlet pipe 5 and the liquid outlet pipe 6 extend into a liquid nitrogen cavity 11, and stop valves 7 are mounted on the surfaces of the liquid inlet pipe 5 and the liquid outlet pipe 6; accessible feed liquor pipe 5 lets in the liquid nitrogen to liquid nitrogen chamber 11 in, and accessible drain pipe 6 discharge liquid nitrogen opens and shuts through stop valve 7 control feed liquor pipe 5 and drain pipe 6.
The surface of the tank body 1 is provided with a controller 3, and the speed reducing motor 43 is electrically connected with an external power supply through the controller 3; the speed reducing motor 43 can be controlled to operate through the controller 3, the operation is simple and convenient, a power supply is not needed, and the manufacturing cost is saved.
The cooling device used in the stem cell cryopreservation process comprises the steps that during operation, a tank body 1 is opened through a sealing cover 8, a test tube is placed in a test tube groove 14, the tank body 1 is sealed through the sealing cover 8, liquid nitrogen is introduced into a liquid nitrogen cavity 11 through a liquid inlet pipe 5, the inner tank 12 is cooled through the liquid nitrogen, a controller 3 can control a speed reducing motor 43 to operate, a power output end of the speed reducing motor 43 rotates to drive a transmission rod 44 to rotate, the transmission rod 44 rotates to drive a transmission wheel 45 to rotate, the transmission wheel 45 rotates to drive a driven wheel 41 meshed with the transmission wheel 45 to rotate, the driven wheel 41 rotates to drive a driven rod 42 to rotate, the driven rod 42 rotates to drive a test tube plate to rotate, the test tube plate rotates to drive the test tube in the test tube groove 14, and mixing efficiency of the stem cells and the cryopreservation liquid is accelerated through the rotation of the test tube.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the utility model as claimed. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (5)
1. A cooling device used in a stem cell cryopreservation process comprises a tank body (1) and a transmission mechanism (4), and is characterized in that supporting legs (2) are fixedly connected to the bottom of the tank body (1), an inner tank (12) is arranged inside the tank body (1), a liquid nitrogen cavity (11) is arranged between the inner tank (12) and the inner side wall of the tank body (1), a transmission cavity (10) is arranged at the bottom of the tank body (1), the transmission mechanism (4) is arranged on the inner side wall of the transmission cavity (10), the transmission mechanism (4) comprises a driven wheel (41), a driven rod (42), a speed reduction motor (43), a transmission rod (44) and a transmission wheel (45), the driven wheel (41) is arranged on the inner side wall of the transmission cavity (10), the driven wheel (41) is installed on the surface of the driven wheel (41), the driven rod (42) is arranged on the surface of the driven wheel (41), and one end of the driven rod (42) extends into the inner tank (12), a speed reducing motor (43) is installed at the bottom of the tank body (1), the power output end of the speed reducing motor (43) is fixedly connected with a transmission rod (44), one end of the transmission rod (44) extends into the transmission cavity (10), a transmission wheel (45) is installed at one end of the transmission rod (44), and the transmission wheel (45) is meshed with a driven wheel (41) and connected with the driven wheel.
2. The cooling device for use in the cryopreservation process of stem cells according to claim 1, wherein: the test tube tray (13) is fixedly connected to the top end of the driven rod (42), and test tube grooves (14) which are uniformly arranged are formed in the surface of the test tube tray (13).
3. The cooling device for use in the cryopreservation process of stem cells according to claim 1, wherein: the tank body (1) is provided with a sealing cover (8) at the top end, and the surface of the sealing cover (8) is fixedly connected with a handle (9).
4. The cooling device for use in the cryopreservation process of stem cells according to claim 1, wherein: jar body (1) lateral wall intercommunication has feed liquor pipe (5) and drain pipe (6) and feed liquor pipe (5) and drain pipe (6) one end to extend to in liquid nitrogen chamber (11), stop valve (7) are all installed on feed liquor pipe (5) and drain pipe (6) surface.
5. The cooling device for use in the cryopreservation process of stem cells according to claim 1, wherein: the surface of the tank body (1) is provided with a controller (3), and the speed reducing motor (43) is electrically connected with an external power supply through the controller (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122110196.8U CN216315106U (en) | 2021-09-02 | 2021-09-02 | Cooling device used in stem cell cryopreservation process |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202122110196.8U CN216315106U (en) | 2021-09-02 | 2021-09-02 | Cooling device used in stem cell cryopreservation process |
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| CN216315106U true CN216315106U (en) | 2022-04-19 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115399313A (en) * | 2022-10-31 | 2022-11-29 | 迈赛凯尔(山东)生命科学有限公司 | Immune cell cryopreserving cooling device |
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2021
- 2021-09-02 CN CN202122110196.8U patent/CN216315106U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115399313A (en) * | 2022-10-31 | 2022-11-29 | 迈赛凯尔(山东)生命科学有限公司 | Immune cell cryopreserving cooling device |
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