CN215130838U - A mouse tail vein syringe - Google Patents
A mouse tail vein syringe Download PDFInfo
- Publication number
- CN215130838U CN215130838U CN202121172147.0U CN202121172147U CN215130838U CN 215130838 U CN215130838 U CN 215130838U CN 202121172147 U CN202121172147 U CN 202121172147U CN 215130838 U CN215130838 U CN 215130838U
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- China
- Prior art keywords
- needle
- buckle
- push rod
- needle cylinder
- injection
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 210000003462 vein Anatomy 0.000 title claims abstract description 38
- 241000581650 Ivesia Species 0.000 title claims abstract description 36
- 238000002347 injection Methods 0.000 claims abstract description 40
- 239000007924 injection Substances 0.000 claims abstract description 40
- 239000008280 blood Substances 0.000 claims abstract description 27
- 210000004369 blood Anatomy 0.000 claims abstract description 27
- 239000012780 transparent material Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 16
- 230000006378 damage Effects 0.000 abstract description 7
- 238000010253 intravenous injection Methods 0.000 abstract description 7
- 208000015181 infectious disease Diseases 0.000 abstract description 4
- 238000013461 design Methods 0.000 abstract description 3
- 238000011160 research Methods 0.000 abstract description 3
- 235000002020 sage Nutrition 0.000 abstract description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 15
- 239000003814 drug Substances 0.000 description 14
- 239000007788 liquid Substances 0.000 description 13
- 210000004204 blood vessel Anatomy 0.000 description 10
- 241000700159 Rattus Species 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 102000004877 Insulin Human genes 0.000 description 3
- 108090001061 Insulin Proteins 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 210000003811 finger Anatomy 0.000 description 3
- 229940125396 insulin Drugs 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 235000009161 Espostoa lanata Nutrition 0.000 description 1
- 240000001624 Espostoa lanata Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 210000004936 left thumb Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The utility model relates to a mouse tail vein injector, which comprises an injection needle head, a needle cylinder and a push rod, wherein the front end of the needle cylinder is connected with a blood return tube, the front end of the blood return tube is fixedly connected with the injection needle head, the tail end of the needle cylinder is provided with a buckle A, and the buckle A is positioned inside the needle cylinder; the front section of the push rod is also provided with a rubber head, the front part of the rubber head is also provided with a protruding pushing head, the tail end of the push rod is provided with a buckle B, the buckle B on the push rod is matched with the buckle A on the needle cylinder, and the push rod is connected with the needle cylinder in a sliding manner. Its advantages are: the utility model discloses simple structure, convenient operation, reasonable in design can reduce the damage of tail intravenous injection in-process to the sage, reduces the probability of mouse tail infection, improves mouse tail intravenous injection success rate, has also reduced the scientific research personnel operation degree of difficulty simultaneously, has improved the efficiency of work.
Description
Technical Field
The utility model belongs to the technical field of animal medicine technique experiment technique and specifically relates to a mouse tail vein syringe.
Background
The syringe is a common medical device, and the principle of the syringe was proposed by kathler, italian in the 15 th century. In medical research, mice are often used as experimental objects, administration is carried out in a certain mode, different administration modes such as intragastric administration, intraperitoneal injection, subcutaneous injection, intravenous injection and the like can be selected due to different drug properties, and the administration modes belong to intravenous injection which is most frequently used and have the highest difficulty. The traditional mouse tail vein injection operation process is as follows: placing a mouse in a fixer, fully exposing a rat tail, repeatedly wiping the rat tail with 75% alcohol or soaking the rat tail in warm water (50 ℃) for 2 minutes to fully expand a tail vein, wiping water with a dry cotton ball, straightening and tightening the rat tail with a left hand, holding a 1ml syringe (generally a No. 4 needle) with a right hand, inserting a needle from the far end (generally from a tail tip 1/4 or 1/3) of the rat tail, if the needle is in a blood vessel, the needle is smooth, and if the liquid medicine is tried to be pushed without resistance, the injection is successful; otherwise, if the needle fails, the needle needs to be inserted again (move to the proximal injection point and try again). After the injection is finished, the medical cotton is used for stopping bleeding.
In the above experimental process, there are several disadvantages: 1. for mice, a 1ml syringe (No. 4 needle) is too thick, is easy to puncture blood vessels of the mice to cause blood vessel injury, and is not suitable for multiple continuous administration. 2. Whether the needle enters the blood vessel cannot be confirmed through the blood return phenomenon. If the method of trying to push the liquid medicine is adopted for judgment, the liquid medicine is easy to lose, and particularly the method is an inexpedient measure for rare liquid medicine; if the needle is withdrawn slowly, whether blood flows out of the skin or not is observed, and the blood can not be found after the needle is withdrawn, and the method has great damage to blood vessels. 3. In order to wait for the liquid medicine to enter blood circulation, the needle needs to be kept for a period of time, the pushing action is kept for a long time, and the working intensity of experimenters is increased. 4. No injector suitable for mouse tail vein injection is available, the currently used 1ml injector is large in size, a large amount of liquid is retained at the joint of needles, a No. 4 needle is too thick, an insulin needle is too soft, and the two types of needles are not easy to enter blood vessels. For this reason, a small animal tail vein injector is proposed to solve the above problems.
The Chinese patent application: CN209075022U discloses a mouse tail vein syringe needle, including needle tubing and needle cover, the surface of insulin syringe needle is provided with the syringe needle, and the inside of puncture board is provided with the recess, and the inside of locating plate is provided with the sponge piece, this mouse tail vein syringe needle, combines insulin syringe needle and needle tubing for the overall device is with low costs, the structure is simple and easy, and can puncture the mouse tail through the syringe needle of 31G specification, improves the success rate of injection. The device can not avoid its push rod to kick-back, is the assembled structure moreover, has the risk that drops, and whether the condition emergence of blood return appears also can not be seen to the device's end portion simultaneously, and overall structure is complicated moreover, and inconvenient medical personnel operate and use.
Therefore, in summary, there is a need for a novel mouse tail vein injector which has a simple structure and is convenient to operate, can reduce damage to a mouse tail during a mouse tail vein injection process, and can improve the success rate of mouse tail vein injection, but no report is found about the novel mouse tail vein injector at present.
Disclosure of Invention
The utility model aims at solving the problems existing in the prior art, and particularly provides a novel mouse tail vein injector.
In order to achieve the purpose, the utility model adopts the technical proposal that:
a mouse tail vein injector comprises an injection needle head, a needle cylinder and a push rod, wherein the front end of the needle cylinder is connected with a blood return tube, the front end of the blood return tube is fixedly connected with the injection needle head, the tail end of the needle cylinder is provided with a buckle A, and the buckle A is positioned inside the needle cylinder; the front section of the push rod is also provided with a rubber head, the front part of the rubber head is also provided with a protruding pushing head, the tail end of the push rod is provided with a buckle B, the buckle B on the push rod is matched with the buckle A on the needle cylinder, and the push rod is connected with the needle cylinder in a sliding manner.
In the mouse tail vein injector, the size of the injection needle is 0.3x8mm as a preferable scheme.
In the mouse tail vein injector, preferably, the blood return vessel is made of transparent material and has a size of 1x5 mm.
In the mouse tail vein injector, as a preferable scheme, the size of the convex pushing head is slightly smaller than that of the blood return pipe.
In the mouse tail vein injector, the specification of the injector is 0.5ml as a preferable scheme.
The utility model has the advantages that:
1. the utility model discloses simple structure, convenient operation, reasonable in design can reduce the damage of tail intravenous injection in-process to the sage, reduces the probability of mouse tail infection, and repeatability is good, can see the blood return and can effectively improve mouse tail intravenous injection success rate, reduces the scientific research personnel operation degree of difficulty.
2. The utility model discloses in the structure setting of buckle has avoided medical personnel to continuously maintain at the injection in-process and has pushed the action, has also alleviateed medical personnel's work burden, has improved the efficiency of work.
Drawings
Fig. 1 is a schematic structural diagram (i) of the mouse tail vein injector of the present invention.
Fig. 2 is a schematic structural view (ii) of the mouse tail vein injector of the present invention.
Detailed Description
The present invention will be further described with reference to the following detailed description. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications can be made by those skilled in the art after reading the disclosure of the present invention, and such equivalents also fall within the scope of the appended claims.
The reference numerals and components referred to in the drawings are as follows:
1. syringe needle 2, syringe 3, push rod
4. Blood return pipe 5, fastener A6, rubber head
7. Convex pushing head 8, fastener B
Example 1A mouse tail vein injector
Referring to fig. 1 and 2, fig. 1 is a schematic structural diagram of the mouse intravenous injector of the present invention (i), and fig. 2 is a schematic structural diagram of the mouse intravenous injector of the present invention (ii).
The device mainly solves the problems that the syringe needle used in the existing experiment is thick and can not confirm whether the needle enters the blood vessel through the blood return phenomenon, and meanwhile, the pushing action needs to be maintained all the time when waiting for observation, thus the workload of medical staff is not increased endlessly, and particularly provides a mouse tail vein syringe to keep the uniformity of the experiment and improve the success rate of tail vein injection of the experiment; the device mainly comprises an injection needle head 1, a needle cylinder 2 and a push rod 3, wherein the front end of the needle cylinder 2 is connected with a blood return tube 4, the front end of the blood return tube 4 is fixedly connected with the injection needle head 1, when the tail end of a mouse is injected, the blood return phenomenon of the mouse can be observed through the blood return tube so as to determine whether the injection needle head 1 enters the blood vessel of the mouse, further the loss of liquid medicine is reduced, meanwhile, the damage to the mouse tail in the mouse tail vein injection process is also reduced, and the probability of mouse tail infection is reduced; the tail end of the needle cylinder 2 is provided with a buckle A5, and the buckle A5 is positioned inside the needle cylinder 2; the front section of the push rod 3 is also provided with a rubber head 6, a convex push head 7 is also arranged in front of the rubber head 6, and the convex push head 7 mainly injects all the liquid remained in the blood return pipe, so that the waste of the liquid medicine is avoided; the tail end of the push rod 3 is provided with a buckle B8, the buckle B8 on the push rod is matched with the buckle A5 on the needle cylinder, the buckle can prevent the syringe from rebounding, and the push rod of the syringe can be remained by the needle cylinder after the mouse vein has pressure in the injection process and stays, so that the problem can be just solved by the buckle, and the buckle in the device can be made of elastic materials; and the push rod 3 is connected with the needle cylinder 2 in a sliding way, the push rod 3 pushes the injection liquid through a rubber plug at the front end, and then the injection of the liquid medicine to the mouse experiment is completed.
In this embodiment, the size of the injection needle 1 is preferably 0.3x8mm, and the injection needle 1 can be set to different sizes as required to meet the requirements of clinical experiments.
In this embodiment, it is preferable that the blood returning tube 4 is made of a transparent material and has a size of 1x5mm, and the blood returning tube 4 is used for observing whether the needle enters the blood vessel of the mouse, so as to improve the success rate of tail vein injection of the mouse.
In this embodiment, the size of the protruding pushing head 7 is preferably slightly smaller than that of the blood return tube 4, so that the liquid medicine can be conveniently and completely injected into the body of the mouse, the fluency during injection is increased, and the waste is avoided.
In this example, the syringe is 0.5ml in size. Because the injection is prepared according to the weight of the mouse in tail vein injection, the injection is generally 0.1ml/10g, the injection amount is not more than 0.5 ml/mouse, and the mice can suffer from congestive heart failure and death due to overlarge injection amount.
The utility model discloses a use method: fixing a mouse, after fixing, beginning to inject liquid medicine into the tail end of the mouse, pinching the two sides of the tail with the left thumb and the index finger to enable veins to be more full, supporting the tail from the lower part with the middle finger, clamping the tail end with the ring finger, holding the injector with the right hand to enable the injection needle head at the front end of the injector to be parallel to the veins (less than 30 degrees), inserting the needle from the lower 1/4 part of the tail, beginning to inject medicine slowly, observing whether the blood return phenomenon exists in the blood return vessel on the injector when the medicine is injected, if the blood return phenomenon exists, indicating that the blood vessel injection is successful, otherwise, readjusting the needle head direction or re-inserting the needle; after the injection is finished, the injector is placed in a designated area, so that unnecessary pollution is avoided, and the operation of the injector is prevented from being influenced.
It should be noted that: the utility model has simple structure, convenient operation and reasonable design, can reduce the damage to the rat tail in the tail vein injection process, reduce the probability of rat tail infection, has good repeatability and can effectively improve the success rate of rat tail vein injection; the structure of the buckle is arranged, so that the medical staff is prevented from continuously maintaining the pushing action in the injection process, the work load of the medical staff is reduced, and the work efficiency is improved; and the device can be applied to various strains of rats and the tail end intravenous injection experiment operation of mice, and is beneficial to popularization and use.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and additions can be made without departing from the principles of the present invention, and these improvements and additions should also be regarded as the protection scope of the present invention.
Claims (5)
1. A mouse tail vein injector is characterized by comprising an injection needle head, a needle cylinder and a push rod, wherein the front end of the needle cylinder is connected with a blood return tube, the front end of the blood return tube is fixedly connected with the injection needle head, the tail end of the needle cylinder is provided with a buckle A, and the buckle A is positioned inside the needle cylinder; the front section of the push rod is also provided with a rubber head, the front part of the rubber head is also provided with a protruding pushing head, the tail end of the push rod is provided with a buckle B, the buckle B on the push rod is matched with the buckle A on the needle cylinder, and the push rod is connected with the needle cylinder in a sliding manner.
2. The mouse tail vein injector of claim 1, wherein the size of the injection needle is 0.3x8 mm.
3. The mouse tail vein injector of claim 1, wherein the blood return tube is made of transparent material and has a size of 1x5 mm.
4. The mouse tail vein injector of claim 1, wherein the size of the protruding pushing head is slightly smaller than the size of the blood return tube.
5. The mouse tail vein injector of claim 1, wherein the injector is 0.5ml in size.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121172147.0U CN215130838U (en) | 2021-05-28 | 2021-05-28 | A mouse tail vein syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121172147.0U CN215130838U (en) | 2021-05-28 | 2021-05-28 | A mouse tail vein syringe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215130838U true CN215130838U (en) | 2021-12-14 |
Family
ID=79373256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121172147.0U Expired - Fee Related CN215130838U (en) | 2021-05-28 | 2021-05-28 | A mouse tail vein syringe |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215130838U (en) |
-
2021
- 2021-05-28 CN CN202121172147.0U patent/CN215130838U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211214 |
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| CF01 | Termination of patent right due to non-payment of annual fee |