CN214485742U - Chromatographic column with temperature control device - Google Patents
Chromatographic column with temperature control device Download PDFInfo
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- CN214485742U CN214485742U CN202023311626.4U CN202023311626U CN214485742U CN 214485742 U CN214485742 U CN 214485742U CN 202023311626 U CN202023311626 U CN 202023311626U CN 214485742 U CN214485742 U CN 214485742U
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Abstract
The utility model provides a chromatographic column with a temperature control device, which comprises a chromatographic column and a water bath kettle, wherein an interlayer is arranged in the chromatographic column; wherein the upper end of the chromatographic column is provided with a water outlet communicated with the interlayer, and the lower end of the chromatographic column is provided with a water inlet communicated with the interlayer; one end of the water bath kettle is communicated with the water outlet through a water outlet pipe, and the other end of the water bath kettle is communicated with the water inlet through a water inlet pipe; a temperature controller is arranged in the water bath kettle; a temperature probe is arranged in the chromatographic column; wherein the temperature probe is electrically connected with the temperature controller; wherein the water inlet pipe is provided with a circulating water pump. The utility model has the advantages that: the device has the advantages of accurate temperature control, simple structure and convenient operation.
Description
Technical Field
The utility model relates to a separator field, concretely relates to chromatography column with heating device.
Background
The chromatographic column is widely applied to organic synthesis separation and analysis experiments, and can effectively remove impurities in a target product so as to achieve the purposes of separation and purification. In the chromatographic process, a plurality of factors affect the chromatographic efficiency, wherein the column temperature is one of the important factors, which not only affects the separation efficiency, but also affects the stability of products when carrying out chromatography on some products sensitive to temperature. The temperature control mode of the current chromatography process is adopted in an air-conditioning room, is greatly influenced by the room temperature, has poor temperature control effect and high energy consumption, and is inconvenient for experimenters to operate.
Disclosure of Invention
In order to solve the problems, the invention discloses a chromatographic column with a temperature control device, which comprises a chromatographic column and a water bath kettle, wherein an interlayer is arranged in the chromatographic column; wherein the upper end of the chromatographic column is provided with a water outlet communicated with the interlayer, and the lower end of the chromatographic column is provided with a water inlet communicated with the interlayer; one end of the water bath kettle is communicated with the water outlet through a water outlet pipe, and the other end of the water bath kettle is communicated with the water inlet through a water inlet pipe; a temperature controller is arranged in the water bath kettle; a temperature probe is arranged in the chromatographic column; wherein the temperature probe is electrically connected with the temperature controller; wherein the water inlet pipe is provided with a circulating water pump.
The utility model discloses the further improvement lies in: wherein, a first control valve is arranged on the water inlet pipe, and a second control valve is arranged on the water outlet pipe.
The utility model discloses the further improvement lies in: the water bath is provided with a refrigeration module and a heating module.
The utility model discloses the further improvement lies in: a eluent placing rack is arranged in the water bath kettle.
The utility model discloses a theory of operation is:
1. circulating water in the water bath kettle is injected into the chromatography column interlayer through a water inlet pipe by a circulating water pump, and a temperature controller is responsible for controlling the temperature of the water bath kettle; the temperature controller is connected with the water bath kettle, controls the heating or refrigerating start of the water bath kettle, opens the first control valve and the second control valve, and the circulating water of the water bath kettle is sent into the water bath kettle through the water inlet pipe and the water outlet pipe in the water inlet interlayer.
2. Because the water bath kettle is provided with the heating and refrigerating modules, the heating or refrigerating can be provided for the eluent used in the chromatography process, and the temperature of the eluent is ensured to be the same as that of the chromatographic column.
3. The column temperature of the chromatographic column is monitored in real time through a temperature probe in the chromatographic column and fed back to a temperature controller, the start or pause of a water bath kettle is controlled through the temperature controller, and meanwhile, the water bath kettle provides heating or refrigeration for the eluent, so that the elution solvent is ensured to be the same as the column temperature.
The utility model has the advantages that: the device has the advantages of accurate temperature control, simple structure and convenient operation.
Drawings
FIG. 1 is a schematic structural view of the present invention;
list of reference numerals:
wherein 1-a second control valve; 2-a chromatographic column; 2-1-sandwich; 3-water bath; 4-a circulating pump; 5-temperature controller; 6-water outlet; 7-a water inlet; 8-water outlet pipe; 9-a water inlet pipe; 10-a temperature probe; 3-1-a refrigeration module; 3-2-a heating module; 11-a first control valve; 12-eluent placing rack.
Detailed Description
The present invention will be further illustrated with reference to the accompanying drawings and specific embodiments, which are to be understood as merely illustrative of the invention and not as limiting the scope of the invention. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.
As shown in FIG. 1, the chromatographic column with a temperature control device of the present embodiment comprises a chromatographic column 2 and a water bath 3, wherein a eluent placing rack 12 is arranged in the water bath 3.
An interlayer 2-1 is arranged in the chromatographic column 2; wherein the upper end of the chromatographic column 2 is provided with a water outlet 6 communicated with the interlayer 2-1, and the lower end is provided with a water inlet 7 communicated with the interlayer 2-1; one end of the water bath 3 is communicated with the water outlet 6 through a water outlet pipe 8, and the other end of the water bath is communicated with the water inlet 7 through a water inlet pipe 9; a temperature controller 5 is arranged in the water bath 3; a temperature probe 10 is arranged in the chromatographic column 2; wherein the temperature probe 10 is electrically connected with the temperature controller 5; wherein the water inlet pipe 9 is provided with a circulating water pump 4; wherein, a first control valve 11 is arranged on the water inlet pipe 9, and a second control valve 1 is arranged on the water outlet pipe 8.
The water bath 3 is provided with a refrigerating module 3-1 and a heating module 3-2.
The embodiment works as follows: firstly, setting the temperature of a water bath 3, opening a first control valve 11 and a second control valve 1, starting a circulating water pump 4, and circulating heated circulating water in an interlayer 2-1 of a chromatographic column 2 to heat the chromatographic column. Circulating water flows in from a water inlet 7 of the chromatographic column and flows out from a water outlet 6 at the upper end to return to the water bath 3, and one complete cycle is completed.
For example, when the return water temperature reaches the set temperature, the temperature controller 5 controls the water bath 3 to reduce the heating power, and the circulating water flow rate is reduced by adjusting the circulating water pump 4. When the return water temperature is lower than the set temperature, the temperature controller 5 controls the water bath to heat, and meanwhile, the circulating water flow rate can be increased through the price-adjusted circulating water pump to heat the chromatographic column 2.
When the circulating pipeline of the device leaks water, the first control valve 11 and the second control valve 1 can be closed to maintain the pipeline, so that water still exists in the cavity of the chromatographic column, and the chromatographic column can be subjected to a certain heat preservation effect.
This device water bath can provide heating or refrigeration for the eluent, temperature probe with temperature controller electric connection in time feeds back the temperature to the temperature controller to adjust the temperature of water bath 3, when the circulating water carries out temperature control to the chromatography column, can place the container that is equipped with the eluent in the water bath, when the column temperature reaches the experimental requirement, can be with the same elution of column temperature in adding the chromatography column, guarantee that chromatography process temperature is even unanimous.
The technical means disclosed in the invention scheme are not limited to the technical means disclosed in the above embodiments, but also include the technical scheme formed by any combination of the above technical features.
Claims (4)
1. The utility model provides a chromatographic column with temperature control device which characterized in that: comprises a chromatographic column (2) and a water bath kettle (3), wherein an interlayer (2-1) is arranged in the chromatographic column (2); wherein the upper end of the chromatographic column (2) is provided with a water outlet (6) communicated with the interlayer (2-1), and the lower end is provided with a water inlet (7) communicated with the interlayer (2-1); wherein one end of the water bath pot (3) is communicated with the water outlet (6) through a water outlet pipe (8), and the other end is communicated with the water inlet (7) through a water inlet pipe (9); a temperature controller (5) is arranged in the water bath pot (3); a temperature probe (10) is arranged in the chromatographic column (2); wherein the temperature probe (10) is electrically connected with the temperature controller (5); wherein the water inlet pipe (9) is provided with a circulating water pump (4).
2. A chromatography column with temperature control device according to claim 1, characterized in that: wherein, a first control valve (11) is arranged on the water inlet pipe (9), and a second control valve (1) is arranged on the water outlet pipe (8).
3. A chromatography column with temperature control device according to claim 1, characterized in that: the water bath (3) is provided with a refrigeration module (3-1) and a heating module (3-2).
4. A chromatography column with temperature control device according to claim 1, characterized in that: a eluent placing rack (12) is arranged in the water bath pot (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023311626.4U CN214485742U (en) | 2020-12-31 | 2020-12-31 | Chromatographic column with temperature control device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023311626.4U CN214485742U (en) | 2020-12-31 | 2020-12-31 | Chromatographic column with temperature control device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214485742U true CN214485742U (en) | 2021-10-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023311626.4U Active CN214485742U (en) | 2020-12-31 | 2020-12-31 | Chromatographic column with temperature control device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214485742U (en) |
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2020
- 2020-12-31 CN CN202023311626.4U patent/CN214485742U/en active Active
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