Noninvasive detection conscious rat electrocardiogram device
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a noninvasive detection clear-headed rat electrocardiogram device.
Background
In the detection of electrocardiogram in rats, anesthesia is performed by intraperitoneal injection of 10% chloral hydrate (0.3ml/100g) in many cases. After anesthesia, the rat is in a supine position and is fixed on an operating table, needles are respectively inserted into the subcutaneous tissues of the two upper limbs and the subcutaneous tissues of the right lower limb of the rat, electrocardiogram electrodes are fixed on the left upper limb (white electrode), the left lower limb (black electrode) and the right lower limb (red electrode), and an RM-6000 physiological signal acquisition and processing system is used for recording the standard, so that the heart rate of the rat is reduced due to anesthesia, and anesthetics such as chloral hydrate and the like have damage to the heart of the rat; the needle electrode needs to pierce the skin, is invasive and is not suitable for multiple tests. Therefore, we propose an electrocardiogram device for non-invasive detection of awake rats.
SUMMERY OF THE UTILITY MODEL
The utility model provides a noninvasive detection clear-headed rat electrocardiogram device aims at blocking the convenience with the rat shank firmly through mutually supporting of four cross slots and perpendicular groove and detects under the clear-headed state of rat to press down the effect through extrusion layer simulation hand, let the rat can not cause the discomfort because of too strong extrusion sense, increase the degree of accuracy that detects.
The utility model provides a specific technical scheme as follows:
the utility model provides a pair of there is not clear-headed rat heart electrograph device of wound detection, comprising a base plate, bottom surface has seted up transverse groove and has four, transverse groove surface fit sliding connection has the fixed block, fixed block fixed surface is connected with the upper cover, the extrusion layer is installed to the upper cover inner wall, it has a plurality ofly to extrude the layer inner wall and install spring and spring, spring surface mounting has the insulating layer, upper cover surface mounting has magic subsides A and magic subsides A to have two.
Optionally, the bottom end of the surface of the bottom plate is provided with a magic tape B.
Optionally, a vertical groove is formed in the surface of the fixing block.
Optionally, the bottom plate and the upper cover are both made of insulating materials.
The utility model has the advantages as follows:
the embodiment of the utility model provides a noninvasive detection clear-headed rat electrocardiogram device:
1. when the electrocardiogram of the rat is detected, the electrocardiogram of the rat is the best in an awake state, the measured data is the most accurate, but the legs of the rat and the like can move disorderly and are inconvenient to measure in the awake state, when the electrocardiogram device for noninvasive detection of the awake rat is used, the transverse grooves are arranged on the surface of the bottom plate, the four transverse grooves are arranged, the surfaces of the transverse grooves are matched and slidably connected with the fixing blocks, the surfaces of the fixing blocks are fixedly connected with the upper cover, and the surfaces of the fixing blocks are provided with the vertical grooves, so that the four limbs of the rat are placed in the transverse grooves, the fixing blocks are inserted at the time, the thighs of the rat are clamped in the inserting process of the fixing blocks, the vertical grooves can leak out the immobile shanks of the rat, the motion amplitude of the shanks is small under the condition of the shanks, and the degreasing cotton sliver soaked with the electrocardiogram conductive paste can be bound on the left upper limb, the left lower limb and the right limb of the rat, and fixing an electrocardiogram electrode on the absorbent cotton strip (wherein the left upper limb is a yellow electrode, the left lower limb is a black electrode, and the right lower limb is a red electrode), wherein the left lower limb is a grounding electrode, and electrocardiosignals are continuously recorded and depicted as rat electrocardiogram by a BL-S type four-channel physiological recorder.
2. In the fixing of the rat body, if the extrusion sense is too large, the body discomfort of the rat can be caused, the rat can be adjusted independently, the electrocardiogram collected by the rat can be disorderly unstable, when the noninvasive detection sober rat electrocardiogram device is used, the fixed block is fixedly connected with the upper cover, the extrusion layer is arranged on the inner wall of the upper cover, the springs are arranged on the inner wall of the extrusion layer, the insulating layer is arranged on the surface of the springs, the magic tapes A and the magic tapes A are arranged on the surface of the upper cover, the magic tapes B are arranged at the bottom end of the surface of the bottom plate, the bottom plate and the upper cover are made of insulating materials, after the legs of the rat are fixed, the insulating layer is attached to the highest position of the back of the rat by pressing the upper cover downwards, and generates certain deformation, then the two magic tapes A are fixed, the elastic rat fixing device comprises a hook and loop fastener A, a hook and loop fastener B, a spring, a fixing piece, an insulating layer, a spring, a fixing piece and an insulator, wherein the hook and loop fastener A and the hook and loop fastener B are fixed to enable the hook and loop fastener A and the hook and loop fastener B not to move greatly, the spring also generates elasticity on the insulating layer when the back of a rat presses the insulating layer, the hook and loop fastener A and the hook and loop fastener B simulate muscles of hands of a person and have certain elasticity but also have great fixing capacity on the rat, so that the rat cannot feel great oppression, excessive resistance cannot be generated during detection, and the insulator is in contact with the rat to avoid the interference of external electric signals on the electrocardiogram of the rat to the greatest extent.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
Fig. 1 is a schematic diagram of the overall structure of an electrocardiogram apparatus for noninvasive detection of awake rats according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a base plate of an electrocardiogram apparatus for noninvasive detection of awake rats according to an embodiment of the present invention;
fig. 3 is a schematic structural diagram of the squeezing layer of the electrocardiograph for non-invasive detection of awake rats according to the embodiment of the present invention.
In the figure: 1. a base plate; 2. a fixed block; 3. a vertical slot; 4. an upper cover; 5. extruding the layer; 6. a spring; 7. an insulating layer; 8. magic tape A; 9. a transverse groove; 10. and (6) magic tape B.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the present invention will be described in further detail with reference to the accompanying drawings, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
An electrocardiogram device for noninvasive detection of awake rats according to an embodiment of the present invention will be described in detail with reference to fig. 1 to 3.
Referring to fig. 1-3, the embodiment of the utility model provides a pair of do not have conscious rat electrocardiogram device of wound detection, including bottom plate 1, 1 surface of bottom plate has been seted up transverse groove 9 and has four, transverse groove 9 surface fit sliding connection has fixed block 2, 2 fixed surface of fixed block are connected with upper cover 4, extrusion layer 5 is installed to 4 inner walls of upper cover, spring 6 and spring 6 have a plurality ofly are installed to 5 inner walls of extrusion layer, 6 surface mounting of spring has insulating layer 7, 4 surface mounting of upper cover has magic subsides A8 and magic subsides A8 to have two.
By way of example, the leg of the rat is firmly clamped through the mutual matching of the four transverse grooves 9 and the vertical grooves 3, so that the rat can be conveniently detected in a waking state of the rat, the pressing effect of the hand is simulated through the extrusion layer 5, the rat cannot feel uncomfortable due to too strong extrusion, and the detection accuracy is improved.
Referring to fig. 2, a magic tape B10 is mounted at the bottom end of the surface of the bottom plate 1.
Illustratively, the adhesion of the magic tape A8 is facilitated.
Referring to fig. 1, a vertical groove 3 is formed on the surface of the fixing block 2.
Illustratively, it is convenient to leak out the rat's lower leg.
Referring to fig. 1, the base plate 1 and the upper cover 4 are both made of an insulating material.
By way of example, interference of external electric signals on the electrocardiogram of the rat is avoided to the maximum extent.
When in use, a healthy rat is selected, a degreasing cotton sliver, an electrocardiogram electrode and a BL-820S biological function experiment system are prepared, because the surface of the bottom plate 1 is provided with four transverse grooves 9, the surfaces of the transverse grooves 9 are matched and slidably connected with the fixed blocks 2, the surfaces of the fixed blocks 2 are fixedly connected with the upper covers 4, and the surfaces of the fixed blocks 2 are provided with the vertical grooves 3, four limbs of the rat are placed in the transverse grooves 9 and then inserted into the fixed blocks 2, the thighs of the rat are clamped in the inserting process of the fixed blocks 2, the vertical grooves 3 can leak the calves of the rat, the motion amplitude of the calves is small under the condition that the calves are not moved, so that the degreasing cotton sliver soaked with the electrocardiogram conductive paste can be bound on the left upper limb, the left lower limb and the right lower limb of the rat, and then the electrocardiogram electrode is fixed on the degreasing cotton sliver (wherein the left upper limb is a yellow lower limb electrode, the left limb is a black electrode, the right lower limb is a red electrode), wherein the left lower limb is a grounding electrode, electrocardiosignals are continuously recorded and described into a rat electrocardiogram by a BL-820S type four-channel physiological recorder, an upper cover 4 is fixedly connected on the surface of a fixed block 2, an extrusion layer 5 is arranged on the inner wall of the upper cover 4, a plurality of springs 6 are arranged on the inner wall of the extrusion layer 5, an insulating layer 7 is arranged on the surface of each spring 6, magic tapes A8 and A8 are arranged on the surface of the upper cover 4, a magic tape B10 is arranged at the bottom end of the surface of a bottom plate 1, the bottom plate 1 and the upper cover 4 are both made of insulating materials, after the legs of the rat are fixed, the insulating layer 7 is attached to the highest position of the back of the rat by pressing the upper cover 4 downwards and generates certain deformation, then the two magic tapes A8 are fixed on the magic tape B10, so that the fixing of the rat is divided into two aspects, firstly, the magic tapes A8 and B10 are fixed so that the magic tapes cannot move greatly, and spring 6 also produces an elasticity to insulating layer 7 when insulating layer 7 is oppressed to rat's back, at this moment both have just imitated the muscle of people's hand, have certain elasticity but still have very big fixed ability to the rat, just so can not let the rat feel very big oppression sense, just can not have too much counter-reaction when detecting, and because all be the insulator furthest with the rat contact and avoided the interference of external signal of telecommunication to rat's heart electrograph, whole device, laminating the normal prone posture of rat as far as possible, rat stress interference when furthest reduction heart electrograph detected, make measured data more accurate, and a rat can repeated measurement also can not cause the injury to the rat.
The utility model relates to a noninvasive detection conscious rat electrocardiogram device, which comprises a base plate 1; 2. a fixed block; 3. a vertical slot; 4. an upper cover; 5. extruding the layer; 6. a spring; 7. an insulating layer; 8. magic tape A; 9. a transverse groove; 10. the magic tape B and the components are all universal standard components or components known by those skilled in the art, and the structure and the principle of the magic tape B can be known by technical manuals or by routine experiments.
It is apparent that those skilled in the art can make various changes and modifications to the embodiments of the present invention without departing from the spirit and scope of the embodiments of the present invention. Thus, if such modifications and variations of the embodiments of the present invention fall within the scope of the claims and their equivalents, the present invention is also intended to include such modifications and variations.