CN213821611U - Thrombectomy support, thrombectomy device and thrombectomy system - Google Patents

Abstract

The utility model relates to a thrombus taking support, a thrombus taking device and a thrombus taking system, wherein the thrombus taking support comprises a rigid unit and a flexible unit which are arranged in a linear shape and are alternately connected; the rigid unit and the flexible unit are both tubular structures which can be compressed and expanded in radial direction; flexible units are more susceptible to buckling deformation than rigid units when subjected to equal radial forces. The rigid units and the flexible units of the tubular structure are alternately connected to form the integral support, wherein the rigid units have a supporting function, can cut and capture thrombus when being naturally unfolded, quickly establish a blood flow channel and realize the pre-communication of the blood flow channel. Utilize flexible unit to carry out radial bending, make and get and tie the support wholly can produce in flexible unit position and buckle, improve the compliance of getting and tying the support, can improve and get and tie the support and after arresting the thrombus, pass the ability of crooked circuitous blood vessel when pullback, ensure to get and tie the support and keep laminating with the vascular wall all the time, avoid the thrombus to drop, finally improve the ability that the thrombus was caught.

Description

Thrombectomy support, thrombectomy device and thrombectomy system

Technical Field

The utility model relates to the technical field of medical equipment, in particular to get and tie support, get and tie device and get system of tying.

Background

Thrombus is formed by abnormal aggregation of blood platelet and other tangible components in blood in circulating blood, and the blood clot is generated on the inner wall or the blood vessel wall of a heart to cause blood vessel blockage or embolism and secondary serious body injury. The thrombus formation is distributed throughout the cardiovascular system, spreads to tissues and organs of the whole body, is not limited to the pathological changes of myocardial infarction, deep venous thrombosis or cerebrovascular thrombosis and the like, and can occur in blood vessels of any part in the body. The incidence rate of venous thrombosis is higher than that of arterial thrombosis, the ratio of the venous thrombosis to the arterial thrombosis can reach 4: 1, the venous thrombosis accounts for 40% -60% of a thrombosis mechanism, the incidence rate of the thrombosis of the blocked coronary artery is 15% -95%, and 90% of thrombosis is accompanied by atherosclerotic plaques. Thrombosis causes vessel occlusion, and blood flow blockage causes related vessel domination tissue ischemia, anoxia and even necrosis to generate corresponding tissue and organ dysfunction symptoms.

At present, anticoagulant drugs and thrombolytic drugs are mostly adopted for treatment in clinic, but the treatment effect is extremely poor, the larger the diameter of a thrombus-blocked blood vessel is, the poorer the treatment effect is, the lower the blood vessel recanalization rate is, the longer the recanalization time is, and some patients are not suitable for thrombolytic treatment.

At present, some mechanical devices are adopted for thrombus removal, a novel and efficient blood vessel recanalization treatment method is provided for thrombus patients, mechanical thrombus removal operation time is short, related complications are few, and the mechanical thrombus removal device is a research hotspot in the field of thrombus treatment at present; according to the shape and function realization form of the mainstream interventional embolectomy device, the mainstream interventional embolectomy device can be divided into the following parts: spiral, screen type, brush type, suction type, stent type. The common defects of the mainstream products are that the thrombus is remained after the thrombus is removed and the thrombus falls off when being withdrawn, so that the performance of capturing the thrombus in the whole thrombus of the thrombus removing device is not ideal. Nerve thrombus takes internal carotid artery, middle cerebral artery, vertebral artery and basilar artery as the good part, the state of acute thrombus is mostly greasy and smooth state, and the existing metal thrombus taking bracket is difficult to capture completely.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a get and tie support to optimize prior art and get the structure of tying the support in the device of tying, promote the performance that the thrombus of getting to tie the support was caught.

Another object of the utility model is to provide a thrombectomy device to optimize the structure of thrombectomy device in the prior art, promote the performance that thrombectomy device's thrombus was caught.

It is another object of the present invention to provide a thrombus removal system to optimize the structure of the thrombus removal system in the prior art, and improve the thrombus capture performance of the thrombus removal system.

In order to solve the technical problem, the utility model adopts the following technical scheme:

according to one aspect of the present invention, there is provided a thrombectomy support, comprising rigid units and flexible units arranged in a linear pattern and alternately connected to each other; the rigid unit and the flexible unit are both tubular structures which can be compressed and expanded radially; the flexible unit is more easily bent and deformed than the rigid unit when subjected to equal radial forces, so that the embolectomy support can be bent at the flexible unit.

According to some embodiments of the invention, the flexible element is configured to expand radially from a first radial dimension to a second radial dimension.

According to some embodiments of the invention, the rigid element and the peripheral wall of the flexible element are all mesh structures.

According to some embodiments of the invention, the flexible unit comprises a connecting piece and a wave ring which are axially and correspondingly connected; the connector is positioned on the distal side of the wave ring; each wave-shaped ring is provided with wave crests and wave troughs which are staggered along the circumferential direction; and part of wave crests of the wave ring are connected with the near end of the connecting piece, and part of wave crests of the wave ring are suspended.

According to some embodiments of the present invention, in the wave ring, it with the connecting piece correspond the crest of meeting and with unsettled crest is crisscross interval arrangement.

According to some embodiments of the present invention, the connecting member comprises a plurality of V-shaped rods circumferentially spaced apart from each other, the V-shaped rods being bent in a V-shape; the vertex of the V-shaped rod is a near end and is connected with the wave crest of the wave-shaped ring; two ends of the V-shaped rod opposite to the vertex of the V-shaped rod are far ends, and the two far ends of the V-shaped rod are used for being connected with the rigid unit or the wave trough of another wave-shaped ring.

According to some embodiments of the invention, the flexible unit is more easily axially compressed than the rigid unit when subjected to equal axial forces; and the radial dimension of the flexible unit is synchronously increased when the flexible unit is axially compressed.

According to some embodiments of the present invention, the flexible unit comprises a plurality of spiral rods spirally wound in the same direction, and the plurality of spiral rods are circumferentially spaced apart from each other; and two ends of the screw rod are respectively connected with one rigid unit.

According to some embodiments of the utility model, the coiling angle of the one end of hob to the other end of this hob is in 0 ~ 360 within range.

According to some embodiments of the present invention, the screw rod comprises a first winding section and a second winding section, one end of which is connected to each other, and both the first winding section and the second winding section are spirally wound; in a natural expansion state, the distance from the first winding section to the central axis of the flexible unit is gradually reduced in the direction away from the second winding section; the distance from the second winding section to the central shaft of the flexible unit is gradually reduced in the direction away from the first winding section; the connection position of the first winding section and the second winding section is the outermost side of the flexible unit in the radial direction.

According to some embodiments of the present invention, the thrombectomy support further comprises a connecting arm, the rigid unit and the flexible unit are connected through the connecting arm, and the connecting arm is rod-shaped.

According to some embodiments of the invention, the linking arm is equipped with a plurality of, a plurality of the linking arm is followed the circumference of rigid unit distributes.

According to some embodiments of the invention, the proximal end and the distal end of the thrombectomy support are the rigid units.

According to some embodiments of the invention, in the natural expansion state, in the direction by near-end to distal end, a plurality of in the thrombectomy support the maximum radial dimension of the flexible unit becomes bigger in proper order.

According to some embodiments of the present invention, for a set formed by rigid units disposed between two adjacent flexible units, the axial lengths of a plurality of the rigid units in the set become smaller in order in a direction from the proximal end to the distal end of the embolectomy stent.

According to some embodiments of the present invention, for a set of rigid units disposed between two adjacent flexible units, a radial dimension of each of the rigid units in the set gradually increases in a direction from the proximal end to the distal end.

According to another aspect of the present invention, the present invention further provides a thrombectomy device, which comprises the above mentioned thrombectomy support and a traction guide wire connected to the thrombectomy support.

According to some embodiments of the present invention, the thrombectomy device further comprises a distal tube and a proximal tube; the most distal end of the thrombus removal support is converged and connected on the distal tube; the proximal end of the thrombus removal support is connected with the proximal tube in a converging manner.

According to some embodiments of the invention, the distal end of the pull guidewire is connected to the proximal tube.

According to some embodiments of the invention, the proximal tube is a hollow tube; the traction guide wire penetrates through the proximal tube and sequentially penetrates through the rigid unit and the flexible unit, and the distal end of the traction guide wire is connected with the distal tube.

According to some embodiments of the present invention, the distal tube is a hollow tube, and the distal end of the pull guide wire is passed out of the distal tube and is engaged with the distal end of the distal tube.

According to some embodiments of the present invention, a heating portion is disposed on the traction guide wire, and the heating portion is correspondingly disposed in the rigid unit or the flexible unit; the pull wire may be electrically connected to an external power source; in the energized state, the heat generating portion is capable of generating heat.

According to another aspect of the present invention, there is provided a thrombus removal system, which comprises the thrombus removal device, a push rod, a loading sheath and a microcatheter; the push rod is connected with the near end of the thrombus taking support and is used for pushing and pulling the thrombus taking support; the loading sheath is used for accommodating the embolectomy device in a compressed state; the micro-catheter is used for being communicated with the loading sheath, and the lumen in the micro-catheter is used for conveying the thrombus removal device.

According to the above technical scheme, the embodiment of the utility model provides an at least have following advantage and positive effect:

the utility model discloses in the thrombectomy support, utilize a plurality of rigidity units and flexible unit to be the straight line and meet in proper order in turn and embolise the supporting structure. The rigid units have a rigid effect, and the plurality of rigid units can play a role of framework support; when the rigid unit is naturally unfolded, the tubular structure of the rigid unit can cut and capture thrombus, and a blood flow channel is quickly established, so that the function of pre-communicating the blood flow channel is realized.

The flexible unit is compared in the rigidity unit and has more flexibility, can carry out radial bending, and then makes and get and tie the support wholly can produce in flexible unit position department and buckle to improve the compliance of getting and tying the support, can improve and get and tie the support and pass the ability of crooked circuitous blood vessel after arresting the thrombus when pullback, ensure to get and tie the support and keep laminating with the vascular wall all the time, avoid the thrombus to drop, finally improve the performance that the thrombus of getting and tying the support was caught.

Drawings

Fig. 1 is a schematic structural view of a first embodiment of a thrombus removal device according to the present invention.

Fig. 2 is a schematic structural view of the embolectomy device shown in fig. 1 in a radially bent state.

Fig. 3 is a schematic structural view of the embolectomy device shown in fig. 1 in an axially compressed state.

Fig. 4 is a schematic structural view of the embolectomy device of fig. 1 before assembly and use.

FIG. 5 is a schematic view of the thrombectomy device of FIG. 4 in an assembled state.

FIG. 6 is a schematic view of the thrombectomy device of FIG. 5 in a deployed state in a microcatheter.

FIG. 7 is a schematic diagram of a first state of the embolectomy device of FIG. 1 during embolectomy.

FIG. 8 is a schematic diagram of a second state of the embolectomy device of FIG. 1 during embolectomy.

FIG. 9 is a schematic diagram of a third state of the embolectomy device in FIG. 1 during embolectomy.

FIG. 10 is a diagram illustrating a fourth state of the embolectomy device in FIG. 1 during embolectomy.

FIG. 11 is a schematic diagram of a fifth state of the embolectomy device of FIG. 1 during embolectomy.

FIG. 12 is a sixth state diagram illustrating the embolectomy process of the embolectomy device shown in FIG. 1.

FIG. 13 is a schematic view of a prior art thrombectomy stent traversing tortuous and tortuous vessels.

FIG. 14 is a schematic view of the thrombectomy stent shown in FIG. 1 traversing a tortuous and tortuous vasculature.

Fig. 15 is a schematic structural view of a second embodiment of the thrombus removal device of the present invention.

Fig. 16 is a schematic structural view of a third embodiment of the thrombus removal device of the present invention.

Fig. 17 is a schematic structural view of a fourth embodiment of the thrombus removal device of the present invention.

Fig. 18 is a schematic structural view of a fifth embodiment of the thrombus removal device of the present invention.

Fig. 19 is a schematic structural view of a sixth embodiment of the thrombus removal device of the present invention.

Fig. 20 is a schematic structural view of a seventh embodiment of the thrombus removal device of the present invention.

Fig. 21 is a side view of the flexible unit shown in fig. 20.

Fig. 22 is another schematic view of the flexible unit shown in fig. 20.

Fig. 23 is a schematic view of yet another construction of the flexible unit shown in fig. 20.

FIG. 24 is a schematic view of the thrombectomy device shown in FIG. 20, shown in a radially flexed state.

Fig. 25 is a schematic structural view of an eighth embodiment of the thrombus removal device of the present invention.

Fig. 26 is a schematic view of the pull wire of fig. 25.

Fig. 27 is a schematic structural view of a ninth embodiment of the thrombus removal device of the present invention.

The reference numerals are explained below:

100/100a/100b/100c/100d/100e/100f/100g/100 h; 200. a push rod; 300. Loading a sheath; 400. a microcatheter; 500. a sheath tube; 600. a joint member; 700. perforating a guide wire;

1/1a/1b/1c/1e/1d/1f/1g/1h, and a thrombus removal bracket; 11/11a/11b/11d, rigid elements; 111. a first wave circle; 1111. wave crest; 1112. a trough of a wave; 12/12c/12d/12e/12f, flexible unit; 121/121e, struts; 1211. a first winding section; 1212. a second winding section; 1211e, a first arc segment; 1212e, a second arc segment; 122. a second wave shaped ring; 1221. wave crest; 1222. a trough of a wave; 123. a connecting member; 124. An annular ring; 13. a connecting arm; 14. a proximal tube; 15. a distal tube; 16. a connecting rod;

2/2f/2g/2h, traction guide wire; 201. a limiting part; 21/21h, guide wire core; 22/22h, heat generating part; 23. An insulating layer; 24. an elastic part.

Detailed Description

Exemplary embodiments that embody features and advantages of the present invention will be described in detail in the following description. It is to be understood that the invention is capable of other and different embodiments and its several details are capable of modification without departing from the scope of the invention, and that the description and drawings are to be regarded as illustrative in nature and not as restrictive.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first", "second", may explicitly or implicitly include one or more of the described features. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

The embodiment of the utility model provides a get and tie support and get and tie device for when the vascular jam blood vessel, the blood vessel of mediation jam catches the thrombus in the jam blood vessel. The thrombus removal device comprises a thrombus removal support and a traction guide wire, wherein the traction guide wire is connected with the thrombus removal support and can be arranged in the thrombus removal support in a penetrating manner. The embolectomy stents have radially telescoping properties that allow for a collapsed state and a naturally expanded state between embolectomy. In the collapsed state, the thrombus taking stent can be conveniently delivered in a blood vessel through a microcatheter and delivered to a diseased region. After reaching the pathological change part, the microcatheter is withdrawn, so that the thrombus taking support can restore to the natural expansion state, the thrombus at the pathological change part is cut and captured, and finally the captured thrombus is withdrawn, and the dredging of the blocked blood vessel is realized.

For ease of description and understanding, as defined herein, "proximal" refers to the end closer to the operator, and "distal" refers to the end further from the operator.

The following is a detailed description of several embodiments of the embolectomy device.

A first embodiment, referring to the structure and use state shown in fig. 1 to 3.

Referring first to fig. 1, the thrombectomy device 100 of the present embodiment includes a thrombectomy support 1 and a pull wire 2.

The thrombus taking support 1 is of a hollow tubular structure, the peripheral wall of the thrombus taking support can be of a grid or mesh structure, and the grid or mesh structure can be of an irregular mesh structure. The traction guide wire 2 passes through the near end of the thrombus taking support 1 and extends into the thrombus taking support 1, and the far end of the traction guide wire 2 is connected with the far end of the thrombus taking support 1. The near end of the traction guide wire 2 can be connected with the outside, and the thrombus removal support 1 can be driven to withdraw towards the near end of the blood vessel by the traction guide wire 2 moving towards the near end of the blood vessel.

The thrombectomy stent 1 has a collapsed state and a natural expanded state. In the collapsed state, the radial dimension of the stent 1 is minimized to facilitate delivery within the vessel and delivery of the stent 1 to the site of the lesion.

The thrombus removal support 1 can be made of memory metal materials, and when external pressure does not exist in the radial direction, the thrombus removal support 1 expands automatically, and the radial size is enlarged. In the natural expansion state, the thrombectomy stent 1 props up the thrombus at the lesion site, and cuts the thrombus by using the grid or mesh structure on the outer peripheral wall of the thrombectomy stent 1, so that the thrombus enters the thrombectomy stent 1 and is captured by the thrombectomy stent 1. Along with the traction of the guide wire 2 to the near end of the blood vessel, the controllable thrombus preparation stent 1 drives the thrombus captured in the controllable thrombus preparation stent to withdraw, and the blocked blood vessel is dredged.

The thrombectomy stent 1 of the present embodiment comprises a rigid unit 11, a flexible unit 12, a connecting arm 13, a proximal tube 14 and a distal tube 15.

The rigid units 11 and the flexible units 12 are arranged in a linear shape and are alternately connected, and the rigid units 11 and the flexible units 12 are connected through connecting arms 13. The most proximal and distal ends of the thrombectomy stent 1 are rigid units 11. The rigid unit 11 has a rigid effect, and a plurality of rigid units 11 can play a skeleton supporting role. The rigid units 11 at the head and the tail can improve the supporting performance and the propelling performance of the embolectomy support 1. The flexible unit 12 is flexible and can be bent and compressed. The rigid unit 11 and the flexible unit 12 are both in a tubular structure capable of radial expansion, and the rigid unit 11 and the flexible unit 12 can be communicated with each other. The peripheral wall of the rigid unit 11 is in a grid or mesh structure, the peripheral wall of the flexible unit 12 is provided with openings communicating the inside and the outside of the tubular structure of the flexible unit 12, or the peripheral wall of the flexible unit 12 is provided with meshes, so that when the rigid unit 11 and the flexible unit 12 are unfolded, thrombus around the rigid unit can be cut, and the cut part of the thrombus enters the tubular structure of the rigid unit 11 or the flexible unit 12 and is captured by the rigid unit 11 or the flexible unit 12.

The rigid unit 11 of the present embodiment has a strong rigidity effect, and has a large radial supporting force. In the natural expanded state, the rigid element 11 has a smaller diameter than the vessel and the flexible element 12. Therefore, when the rigid unit 11 is unfolded, no wound is caused to the blood vessel, and the blood flow channel can be quickly established, so that the pre-passing function of blocking the blood flow channel at the blood vessel is realized.

Referring to fig. 1, the rigid unit 11 in the present embodiment is a grid unit, and the grid unit is a network tube structure.

Further, the grid unit of the present embodiment mainly includes a plurality of first wavy circles 111 connected in the axial direction. Each first wave ring 111 has crests 1111 and troughs 1112 staggered in the circumferential direction. With peaks 1111 oriented distally and valleys 1112 oriented proximally. The wave crests 1111 of the proximal first wave ring 111 are correspondingly connected with the wave troughs 1112 of the distal first wave ring 111 to form a grid structure.

As shown in fig. 1, the rigid unit 11 has two first wave rings 111, and each first wave ring 111 can be regarded as a closed loop structure formed by a rod member extending in a continuous bending manner in a Z-shape or a W-shape. The wave troughs 1112 of the first proximally located wave ring 111 are connected to the connecting arms 13 or are convergently connected to the proximal tube 14. The peaks 1111 of the first distal undulating ring 111 are connected to the attachment arms 13 or convergently connected to the distal tube 15. The grid structure between two adjacent first wave-shaped circles 111 is a diamond grid, and other grid shapes such as triangle, rectangle or polygon can also be formed.

The first wave rings 111 and the whole rigid unit 11 can be extended and contracted in the radial direction so that adjacent peaks 1111 and adjacent valleys 1112 between the respective first wave rings 111 can be close to or distant from each other. At the time of natural expansion, the diameter of the first wave ring 111 becomes large, and the axial interval between the crests 1111 and the troughs 1112 becomes small while the circumferential interval becomes large. When the thrombus taking support 1 reaches the thrombus position of a lesion part, the rigid unit 11 is expanded through the self-expansion of the first wavy ring 111, so that the thrombus can be expanded, a blood flow channel is established, and the function of pre-passing is realized; and the thrombus is cut by the first wavy ring 111, and the cut part of the thrombus enters the first wavy ring 111 to be captured by the lattice cells.

In this embodiment, the flexible unit 12 is more flexible than the rigid unit 11.

Referring to fig. 2, when the same radial force is applied, the flexible unit 12 of the present embodiment is more easily bent and deformed than the rigid unit 11, so that the thrombectomy stent 1 can be bent at the flexible unit 12, thereby ensuring the effect of the thrombectomy stent 1 in capturing thrombus, and simultaneously considering the overall flexibility of the thrombectomy stent 1, so that the thrombectomy stent 1 can be delivered and retracted in a tortuous blood vessel.

Referring to fig. 3, the flexible unit 12 of the present embodiment is more easily compressed axially than the rigid unit 11 when subjected to the same axial force; and its maximum radial dimension D1 increases simultaneously as the flexible unit 12 is axially compressed.

In the naturally expanded state, the maximum radial dimension D1 of the flexible element 12 is greater than the maximum radial dimension D2 of the rigid element 11. A space 10 can be formed between two adjacent flexible units 12, and thrombus in the space 10 is distributed on the periphery of the corresponding rigid unit 11, and is not cut by the grid structure of the rigid unit 11, so that the integrity of the space is maintained.

In the process of withdrawing the thrombus taking support 1, the flexible unit 12 can push the complete thrombus in the interval space 10 to withdraw, so that the risk of thrombus falling is reduced, and the success rate of thrombus taking is improved. At the same time, since the uncut thrombus is mainly confined within the interstitial space 10, the stent 1 exerts a force on the thrombus substantially in a direction parallel to the blood vessel when it is withdrawn, which means that the action of the stent 1 on the thrombus does not serve to increase the force required to remove the thrombus from the blood vessel, thereby protecting the delicate blood vessel (e.g., cerebral blood vessel) from harmful radial and tensile forces.

It should be noted that, if the maximum radial dimension D1 of the flexible unit 12 is smaller than the maximum radial dimension D2 of the rigid unit 11, the spacing space 10 is formed between two adjacent rigid units 11, and when the thrombus stent 1 is withdrawn, and passes through a bent blood vessel, the flexible unit 12 is bent to protrude to one side, so that the thrombus in the spacing space 10 between two rigid units 11 is extruded out of the spacing space 10, which is not beneficial to catching and withdrawing the thrombus, as shown in fig. 13 and 14. The option of using a flexible element 12 with a maximum radial dimension D1 greater than the maximum radial dimension D2 of the rigid element 11 is chosen.

It should also be noted that, in the natural expanded state, the maximum radial dimension D1 of the flexible units 12 may be smaller than the maximum radial dimension D2 of the rigid units 11, and the spacing space 10 may be formed between adjacent flexible units 12 only by making the maximum radial dimension D1 of the flexible units 12 larger than the maximum radial dimension D2 of the rigid units 11 after the flexible units 12 are axially compressed.

Still referring to fig. 3, when the embolectomy stent 1 is subjected to squeezing forces at the opposite axial ends, the maximum radial dimension D1 of the flexible unit 12 of the present embodiment is increased, and the axial dimension is decreased; while the maximum radial dimension D2 and the axial dimension of the rigid element 11 remain unchanged. Therefore, based on the characteristic that the maximum radial dimension D1 of the flexible unit 12 is variable, when the thrombus removal stent 1 is withdrawn from the far end of the blood vessel to the near end of the blood vessel, if the diameter of the blood vessel is gradually increased, the flexible unit 12 of the thrombus removal stent 1 can be always kept in an adherent state in different blood vessel sections by adjusting the maximum radial dimension D1 of the flexible unit 12, so that the thrombus inside the thrombus removal stent 1 and the massive thrombus in the interval space 10 can be removed during withdrawal, the effect and success rate of thrombus removal are improved, and the risk of thrombus falling off is reduced.

In addition, the thrombus extraction support 1 formed by the rigid units 11 and the flexible units 12 alternately is of a sectional type structure, when the thrombus captured by the thrombus extraction support 1 is withdrawn to the guide catheter or the middle catheter, the proximal structure of the thrombus extraction support 1 is compressed due to entering the guide catheter or the middle catheter, the change of the rear structure cannot be caused, and therefore, the thrombus falling caused by the integral compression of the thrombus extraction support 1 during the withdrawal can be avoided.

The flexible unit 12 in this embodiment includes a plurality of struts 121, and the plurality of struts 121 are arranged at intervals in the circumferential direction to form a cylindrical structure. The spaces between adjacent struts 121 are spaced to form openings or meshes in the outer peripheral wall of the flexible unit 12; both ends of the rod 121 are connected to a connecting arm 13, respectively. The ends of adjacent struts 121 may be spaced apart to provide uniform spacing between adjacent struts 121. The ends of adjacent struts 121 also partially meet to facilitate connection to the connecting arm 13. Each strut 121 is capable of expanding radially outward to progressively increase the radial dimension of the flexible unit 12 as the flexible unit 12 is axially compressed.

Referring to fig. 1, the supporting rod 121 in this embodiment is a spiral rod, and a plurality of supporting rods 121 are spirally wound clockwise or counterclockwise along the same direction, so that the flexible unit 12 forms a spiral unit. The spiral rods may be understood as being of a wire or rod-like configuration and wound in a spiral, with the spaces between adjacent rods forming openings or meshes in the outer peripheral wall of the flexible unit 12. The spiral winding angle from the near end to the far end of the spiral rod is not more than 360 degrees, wherein the larger the winding angle is, the better the flexibility is, and the weaker the support is.

The screw rod is divided into a first winding section 1211 and a second winding section 1212 according to a distance from the screw rod to a center line of the screw unit, and the first winding section 1211 and the second winding section 1212 are connected at one end and spirally wound in the same direction. The junction of first winding section 1211 and second winding section 1212 is the outermost side of flexible unit 12 in the radial direction. First wound section 1211 is gradually spaced apart from the central axis of flexible unit 12 in a direction gradually away from second wound section 1212. Second wound section 1212 has a gradually decreasing distance from the central axis of flexible unit 12 in a direction gradually away from first wound section 1211.

The spiral unit can be bent under the action of radial pressure; it is also possible to perform axial compression under axial pressure. When the axial compression, the spiral unit carries out synchronous radial expansion to realize the abundant laminating with the vascular wall, and fully contact with the thrombus, realize the effect of maximum gomphosis. While the expanded flexible unit 12 has a larger diameter than the rigid unit 11, so that the rigid unit 11 does not contact the vessel wall.

In the embodiment, the flexible units 12 forming the spiral units and the rigid units 11 forming the grid units are sequentially arranged at intervals and alternately, so that the thrombus removal support 1 is integrally formed into a sectional structure, the flexibility of the thrombus removal support 1 is improved, and the thrombus removal support can adapt to blood vessels with different bending forms. The grid structure of the rigid unit 11 embedded into the thrombus can open the inside of the thrombus through the radial supporting force of the grid structure, so that a blood flow channel is quickly established, and the function of pre-dredging of blood vessels is blocked in real time; the lattice structure of the rigid cells 11 also enables the formation of a catching structure, cutting and catching the thrombus when deployed. The spiral unit is a flexible structure and is in a compressed state when being expanded inside the thrombus. At the moment, the external force is utilized for compression, the guide wire 2 is pulled to retract towards the near end relative to the thrombus taking support 1, so that the spiral unit is fully expanded, the spiral rod cuts thrombus, the spiral unit is embedded with the thrombus to the maximum degree, and the spiral unit is attached to the vascular wall. The spiral cells in the expanded state have a larger diameter than the grid cells and adjacent spiral cells form a space 10 therebetween. The thrombus which is not cut by the grid unit and is positioned in the interval space 10 can keep higher integrity, the risk of falling of the thrombus can be reduced in the withdrawing process, and the effect and the success rate of taking out the thrombus are further improved.

In this embodiment, both the spiral unit and the grid unit can be made of memory alloy or polymer material. Specifically, the nickel-titanium composite material can be formed by weaving or laser cutting a nickel-titanium pipe, can also be formed by coiling and heat setting after laser cutting a nickel-titanium plate, can also be formed by weaving a nickel-titanium wire material, can also be formed by processing an elastic plastic material, and the like.

As shown in fig. 1 in particular, the embolectomy stent 1 of the embodiment is formed by alternately connecting four rigid units 11 and three flexible units 12 in sequence. It should be noted that the number of the rigid units 11 and the flexible units 12 is not limited, and may be increased accordingly, and the design is performed as required.

The rigid unit 11 and the flexible unit 12 are connected by a connecting arm 13. The connecting arm 13 is connected at one end to the rigid unit 11 and at the other end to the flexible unit 12. The connecting arm 13 may be parallel to the central axis of the thrombectomy holder 1, and the connecting arm 13 may be rod-shaped and extend in the axial direction of the thrombectomy holder 1. The connecting arm 13 may also be a curved or spiral arm. The use of the attachment arms 13 allows for a better transition between the rigid elements 11 and the flexible elements 12 to allow for bending between two adjacent rigid elements 11 in the stent 1 without compromising the expandability of the flexible elements 12 as much as possible and to maintain the ability of the flexible elements 12 to align and adhere well to the vessel wall.

Specifically, one end of the connecting arm 13 may be connected to the wave crest 1111 or the wave trough 1112 of the first undulating coil 111 in the lattice unit, and the other end of the connecting arm 13 may be connected to one end of one or more helical rods in the helical unit. Between the adjacent rigid units 11 and flexible units 12, the connecting arm 13 may be provided in plurality. A plurality of connecting arms 13 are arranged at intervals around the axis of the rigid unit 11. In the embodiment, as shown in fig. 1, four connecting arms 13 are provided, and one end of each connecting arm 13 is connected to a spiral rod, and the other end is connected to the wave crest 1111 or the wave trough 1112 of the first wave shaped ring 111.

On the embolectomy stent 1, the proximal end of the most proximal rigid unit 11 adopts a conical structure and is connected to the proximal tube 14 in a converging manner. The conical structure is adopted, the overall flexibility of the proximal structure of the embolectomy stent 1 can be improved, and the embolectomy stent 1 can conveniently enter the guide catheter or the sheath 500 when being withdrawn.

On the thrombectomy stent 1, the distal end of the most distal rigid unit 11 adopts a conical structure and is connected to the distal tube 15 in a converging manner. The far end of the most far end rigid unit 11 is in a conical structure, so that damage to thrombus in the propelling process of the thrombus removal support 1 can be reduced, and the risk of broken thrombus flowing to the far end of a blood vessel is reduced.

In this embodiment, the proximal tube 14 is a hollow tube, and the pull guide wire 2 passes through the proximal tube 14 and sequentially passes through the rigid unit 11 and the flexible unit 12; the distal end of the pull wire 2 is connected to the distal tube 15.

The distal tube 15 may also be a hollow tube, and the distal end of the pull guide wire 2 is provided with a limiting portion 201, and the limiting portion 201 may be a spherical structure. After the distal end of the pull guide wire 2 passes through the distal tube 15 having a hollow structure, the distal end is engaged with the distal end of the distal tube 15 by the stopper 201. And when the traction guide wire 2 is retracted, the traction guide wire 2 can drive the thrombus removal support 1 to retract. It will be appreciated that the distal end of the pull wire 2 may also be welded to the distal tube 15.

Referring to fig. 4 to 6, before use, the thrombus removal device 100 according to the embodiment of the present invention is loaded in a collapsed state in a thrombus removal system, and the thrombus removal system further includes the push rod 200, the loading sheath 300, the microcatheter 400, and the sheath tube 500.

The proximal end of the thrombus taking support 1 is connected on the proximal tube 14 in a gathering mode through the rigid unit 11, the hollow proximal tube 14 is communicated with the push rod 200, the push rod 200 is a flexible tube capable of being bent in the radial direction, and the proximal end of the traction guide wire 2 sequentially penetrates out of the proximal tube 14 and the push rod 200.

The loading sheath 300 is sleeved outside the push rod 200, and the thrombectomy stent 1 is pre-compressed and guided into the loading sheath 300 before use, as shown in the state of fig. 4.

When a thrombectomy procedure is required, the loading sheath 300 may be connected to the microcatheter 400 via a connector 600 (e.g., a luer connector), as shown in FIG. 5. The proximal tube 14 and the thrombectomy stent 1 are further pushed by the push rod 200 to enter the lumen of the microcatheter 400 smoothly, as shown in FIG. 6. The thrombus removal device 100 is then conveyed to the lesion position of the thrombus determined by radiography or other diagnostic means through the microcatheter 400, so that the thrombus removal stent 1 is released at the vascular lesion position and can be accurately aligned by the push rod 200 through push-pull action, and the thrombus removal stent 1 is converted between the compression state and the release state.

The sheath 500 is sleeved outside the micro-catheter 400, and the sheath 500 extends into the blood vessel along with the micro-catheter 400 and is conveyed to the proximal end of the thrombus at the lesion part for accommodating the thrombus captured by the thrombus removal stent 1 during retraction.

Referring to fig. 7 to 12, in the interventional embolectomy, referring to fig. 7, a perforated guide wire 700 is used to pass through the thrombus in the lesion in advance to establish a vascular access in the thrombus. Referring to fig. 8, the microcatheter 400 and sheath 500 are delivered over the fenestrated guidewire 700 to the thrombus at the lesion site, and the microcatheter 400 is passed over the thrombus, securing the microcatheter 400, and withdrawing the fenestrated guidewire 700. Referring to FIG. 9, the thrombectomy device 100 is pushed by the push rod 200 to the location of the thrombus as determined by visualization or other diagnostic means. Referring to fig. 10, the push rod 200 is stopped, the push rod 200 is fixed and the micro-catheter 400 is withdrawn, so that the thrombectomy stent 1 is released at the far end of the micro-catheter 400, the thrombus is ensured to be positioned in the effective area of the thrombectomy device 100 according to the position of the developing point on the image, and the thrombectomy stent 1 is completely released in the blood vessel. Referring to fig. 11, the pull wire 2 can be adjusted according to the wall thickness of the blood vessel, so that the spiral unit is expanded and anchored on the blood vessel wall, and the spiral unit is fully attached to the blood vessel wall and catches thrombus. Referring to fig. 12, the pull wire 2 and the push rod 200 are pulled simultaneously to withdraw the thrombectomy stent 1 with the captured thrombus and into the sheath 500, completing the thrombectomy.

Referring to fig. 13, when the conventional integrated thrombus-retrieval stent 1 is withdrawn in a continuous and tortuous blood vessel, due to the extrusion effect of the rounded corners, the thrombus-retrieval stent 1 is compressed into a linear shape during the withdrawal process, and is embedded with thrombus, so that the volume is reduced, the probability of thrombus falling off is increased, and the thrombus-retrieval effect and success rate are reduced.

Referring to fig. 14, the thrombectomy stent 1 provided in this embodiment can be radially expanded to be completely embedded into the thrombus by the combined action of the elastic release of the shape memory material and the external force pulling. Due to the flexibility of the stent and the variable diameter of the inner spiral unit, the stent can be fully expanded at the tortuous part of the blood vessel and kept relatively static with thrombus during withdrawal, so that the thrombus is effectively prevented from falling off, and the effect and success rate of thrombus extraction are improved. In addition, when the thrombus removal stent 1 is withdrawn from a far-end blood vessel to a near-end blood vessel, the diameter of the blood vessel wall gradually increases, the thrombus removal device 100 can be kept in an adherent state at different sections of the blood vessel all the time by adjusting the diameter of the spiral unit, the thrombus falling risk can be further reduced, and the thrombus removal effect and the success rate can be improved.

The second embodiment, refer to the structure shown in fig. 15.

The embolectomy device 100a of this embodiment is similar in structure to the first embodiment, except that the rigid unit 11a is designed differently. Specifically, in the embolectomy stent 1a of the present embodiment, among the rigid units 11a other than the two rigid units 11a located at the most proximal end and the most distal end, the axial lengths of the plurality of rigid units 11a become smaller in order in the direction from the proximal end to the distal end of the embolectomy stent 1 a. The axial length of the rigid unit 11a can be adjusted by changing the number of the first bellows rings 111.

The maximum radial dimension D1 of the flexible units 12a is larger than the maximum radial dimension D2 of the rigid unit 11a, so that between two adjacent flexible units 12a, a space 10 can be formed to catch thrombus. The axial dimension of the spacing space 10 may vary with the change in the axial length of the rigid unit 11 a. Therefore, as the axial length of each rigid unit 11a is sequentially decreased from the proximal end to the distal end, the axial dimension of each compartment 10 is also decreased in synchronization, and the size of the thrombus in each compartment 10 is regularly decreased.

When the thrombus taking stent 1a is withdrawn in a circuitous blood vessel, the far-side spacing space 10 can not accommodate large thrombus at the near side, so that the large thrombus at the near-side spacing space 10 can be effectively prevented from migrating to the far-side spacing space 10, the large thrombus can be prevented from escaping to a farther position, and the risk of thrombus falling off is further reduced.

It should be noted that the axial dimension of each compartment 10 may vary in other ways, such as in the proximal to distal direction, the axial dimension of each compartment 10 may become larger in order, or may be arranged in an alternating size configuration, or may be randomly arranged, etc.

A third embodiment, see the structure shown in fig. 16.

The embolectomy device 100b of this embodiment is similar in structure to the first embodiment, except that the rigid unit 11b is designed differently.

Specifically, in the thrombectomy stent 1b of the present embodiment, the radial width of each rigid unit 11b becomes gradually larger in the proximal to distal direction in the rigid units 11b except for the two rigid units 11b located at the proximal and distal ends. The radial width of the rigid unit 11b can be adjusted by changing the distance from each first undulating ring 111 in the rigid unit 11b to the central axis of the rigid unit 11 b.

In the direction from the proximal end to the distal end, as the radial width of the rigid unit 11b gradually increases, the surface of the rigid unit 11b can be made to have a tapered structure, so that the size of the corresponding formed space 10 also becomes gradually smaller. Corresponding to the formation of a large thrombus mass in the space 10, the structure gradually decreases in size from the proximal end to the distal end. Therefore, the large thrombus in the spacing space 10 can be effectively prevented from migrating to the far side and escaping to the farther position, and the risk of thrombus falling off is further reduced.

A fourth embodiment, see the structure shown in fig. 17.

The embolectomy device 100c of this embodiment is similar in structure to the first embodiment, except that the flexible unit 12c is designed differently.

Specifically, in the thrombectomy stent 1c of the present embodiment, in the natural expansion state, the maximum radial dimension D1 of each flexible unit 12c becomes larger in sequence from the proximal end to the distal end of the thrombectomy stent 1c, so that the distal flexible unit 12c can be compressed in the axial direction to adjust the maximum radial dimension D1 thereof to fit larger vessels.

In the process of withdrawing the thrombus removal stent 1c, as the blood vessel becomes larger gradually, the flexible unit 12c at the far side can have a larger maximum radial dimension D1 to be attached to the wall of the blood vessel, so that the thrombus in the space 10 is prevented from escaping far away, and the risk of thrombus falling off is further effectively reduced.

In a fifth embodiment, reference is made to the structure shown in fig. 18.

The embolectomy device 100d of this embodiment is similar in structure to the first embodiment, except that the structure of the connecting arm 13 is omitted between the rigid unit 11d and the flexible unit 12d, and the rigid unit 11d and the flexible unit 12d of the embolectomy stand 1d are directly connected.

In this embodiment, the end of the helical rod of flexible unit 12d is directly connected to the crest 1111 or the trough 1112 of the first undulating turn 111 of rigid unit 11 d.

A sixth embodiment, see the structure shown in fig. 19.

The embolectomy device 100e of the present embodiment is different from the first embodiment in the structure of the flexible unit 12 e.

The flexible unit 12e of the embolectomy support 1e in this embodiment includes a plurality of struts 121e, and the struts 121e are circumferentially spaced to form a cylindrical structure. The interstitial spaces between adjacent struts 121e form openings or meshes in the outer peripheral wall of the flexible unit 12 e; both ends of the rod 121e are connected to a connecting arm 13, respectively.

Referring to fig. 19, in the natural expansion state, the supporting rod 121e is an arc-shaped rod, the arc-shaped rod extends along the axial direction of the bolt-taking bracket 1e, the middle portion of the arc-shaped rod protrudes outward in an arc shape along the radial direction of the bolt-taking bracket 1e, and the arc-shaped rods are circumferentially spaced around the axis of the bolt-taking bracket 1e, so that the flexible unit 12e is in an approximately spherical or ellipsoidal shape in the natural expansion state. When carrying out axial compression to flexible unit 12e, the axial interval at arc pole both ends diminishes gradually to the middle part of arc pole radially expands outward, and the degree grow of evagination, thereby makes flexible unit 12 e's maximum radial dimension D1 grow gradually, with the realization with the abundant laminating of vascular wall, with the thrombus fully contact, realizes the effect of maximum gomphosis.

The curved rod may be divided into a first curved section 1211e and a second curved section 1212e according to the distance from the curved rod to the center line of the flexible unit 12e, and the first curved section 1211e and the second curved section 1212e are connected at one end. The junction of the first arc-shaped section 1211e and the second arc-shaped section 1212e is the outermost side of the flexible unit 12e in the radial direction. The first curved section 1211e has a gradually decreasing distance from the central axis of the flexible unit 12e in a direction gradually away from the second curved section 1212 e. The second arc-shaped section 1212e has a gradually decreasing distance from the central axis of the flexible unit 12e in a direction gradually away from the first arc-shaped section 1211 e.

Further, the flexible unit 12e also includes annular rings 124 at both ends of the curved rod. The two annular rings 124 are arranged at intervals, and the annular rings 124 are arranged around the axis of the embolectomy support 1 e. The arc-shaped rods are connected at both ends with an annular ring 124, respectively, and the annular ring 124 can be directly connected with the rigid unit 11 or connected with the rigid unit 11 through a connecting arm 13. The annular ring 124 may be resilient to facilitate contraction and expansion with the embolectomy holder 1e as a whole.

The seventh embodiment, refer to the structures shown in fig. 20 to 24.

The embolectomy device 100f of the present embodiment is different from the first embodiment in the structure of the flexible unit 12f and the pull wire 2 f.

In this embodiment, the outer peripheral wall of the flexible unit 12f of the embolectomy holder 1f is of a mesh structure, and the flexible unit 12f is of a mesh tubular structure as the rigid unit 11, and the mesh structure forms an opening in the outer peripheral wall of the flexible unit 12 f.

In a specific embodiment, referring to fig. 20 and 21, the flexible unit 12f includes a connecting member 123 and a second wave ring 122 that are axially connected to each other. The connector 123 is located on the distal side of the second undulating ring 122.

The connecting members 123 and the corresponding second undulating rings 122 may be provided in a plurality of sets, and the connecting members 123 and the second undulating rings 122 between the plurality of sets are alternately connected in sequence, so that the length of the flexible unit 12f can be increased, as shown in fig. 22 and 23.

Each second undulating ring 122 has circumferentially alternating peaks 1221 and valleys 1222. With the peaks 1221 facing distally and the valleys 1222 facing proximally.

In the second wave ring 122, a part of the wave peaks 1221 thereof is connected to the proximal end of the connecting member 123, and a part of the wave peaks 1221 are suspended. Thereby forming a grid structure of the flexible units 12f and forming gaps at the suspended peaks 1221.

Specifically, the connecting member 123 may employ a plurality of rods bent in a V shape. The tip of each V-shaped link 123 is proximal and meets the crest 1221 of the second undulating ring 122. Two ends of the V-shaped connecting piece 123 opposite to the tip are far ends, and the two far ends are respectively connected with a connecting arm 13; the two distal ends may also be used to meet the wave trough 1222 of another adjacent second undulating ring 122 when the connectors 123 and second undulating rings 122 between the sets are alternately connected in sequence. A plurality of connectors 123 are circumferentially spaced and cooperate with the second undulating ring 122 to form a tubular structure. A grid or mesh structure may be formed between the connection 123 and the peaks 1221 or valleys 1222 of the second undulating ring 122.

Referring to fig. 24, under the action of a radial external force, the flexible unit 12f may be bent at the notch formed by the suspended wave peak 1221, so as to improve the flexibility of the thrombectomy stent 1f and adapt to the curved blood vessel.

Referring to fig. 21, in the proximal-to-distal direction, the distance from the center line of the flexible unit 12f to the second undulating ring 122 gradually increases, so that the suspended peak 1221 of the second undulating ring 122 forms an outwardly expanded free end. The maximum width of the flexible unit 12f at the free end is the maximum radial dimension D1 of the flexible unit 12f, which is D1 is greater than the maximum radial dimension D2 of the rigid unit 11. Between the second wave turns 122 of two adjacent groups, the free ends formed by the suspended peaks 1221 may be located at the same position or distributed crosswise, as shown in fig. 22 and 23.

The flexible units 12f are capable of flexing in a radial direction such that adjacent peaks 1221 between the second undulating rings 122 and adjacent valleys 1222 may be closer to or farther from each other. When the flexible unit 12f is naturally expanded in the thrombus, the free ends formed by the suspended peaks 1221 can become embedded in the thrombus and conform to the vessel wall. The interstitial spaces 10 are formed between the corresponding suspended peaks 1221 of adjacent flexible units 12 f. When the thrombus taking support 1f is withdrawn, the free end formed by the suspended wave peak 1221 can push the complete thrombus in the interval space 10 to be withdrawn, so that the success rate of thrombus taking out is improved. Meanwhile, the free end formed by the suspended wave peak 1221 extends from the proximal end to the distal end, so that the thrombus removal stent 1f is not prevented from contracting into the sheath 500 when being retracted.

It should be noted that the maximum radial dimension D1 of the flexible unit 12f is greater than the maximum radial dimension D1 of the rigid unit 11, and is adjustably controllable by the diameter of the second undulating ring 122 at the peak 1221.

Further, in the second wave ring 122, the wave peak 1221 corresponding to the proximal end of the connecting member 123 and the suspended wave peak 1221 are arranged in a staggered and spaced manner.

Notably, the flexible unit 12f of this embodiment is not radially expandable by axial compression.

Referring specifically to fig. 20, the flexible unit 12f has a second undulating ring 122 and a connecting member 123. Wherein the connecting member 123 is formed of two opposite V-shaped rod members. The second undulating ring 122 may be viewed as a closed loop structure formed by a continuous curved extension of the rod in a Z-shape or W-shape having four distal peaks 1221 and four proximal valleys 1222. Two of the peaks 1221 are connected to the connecting member 123, and the other two peaks 1221 form free ends that are suspended. The wave 1221 connected with the connecting piece 123 is arranged at intervals with the suspended wave 1221.

Referring to fig. 20 and 24, in the present embodiment, the distal end of the pull wire 2f is directly connected to the proximal end of the thrombectomy stent 1f, i.e., connected to the proximal tube 14, and the pull wire 2f does not need to extend into the thrombectomy stent 1f for deployment. The near end of the traction guide wire 2f can be connected with the outside, and the thrombus removal support 1f can be driven to be integrally withdrawn towards the near end by the traction guide wire 2f moving towards the near end of the blood vessel.

An eighth embodiment, see the structure shown in fig. 25 and 26.

The thrombectomy device 100g of the present embodiment is similar to the first embodiment, except that the traction guidewire 2g is designed differently.

The traction wire 2g of the present embodiment includes a wire core 21 and a heat generating portion 22 provided on the wire core 21.

The guide wire core 21 is made of conductive material and is arranged in the thrombus removal support 1g in a penetrating mode. One end of the guide wire core 21 extends out of the embolectomy bracket 1g and can be electrically connected to an external power supply; the heating part 22 is positioned in the bolt taking bracket 1 g; when the guide wire core 21 is in a power-on state, the heating part 22 can generate joule heat, so that thrombus in the area around the heating part 22 is dehydrated, contracted and solidified, and is tightly bonded with the heating part 22, the capturing effect of the thrombus is improved, and further, when the thrombus taking support 1g and the traction guide wire 2g are withdrawn, the thrombus can be effectively prevented from falling off, and the effect and the success rate of taking out the thrombus are improved.

The external power source can be a radio frequency power source, and when radio frequency current is applied to the guide wire core 21, a radio frequency thermal ablation effect can be formed around the heating part 22.

The region of the guide wire core 21 other than the heat generating portion 22 is covered with an insulating layer 23. The insulating layer 23 is a layer of insulating material wrapped around the guide wire core 21 and can be sleeved or bonded on the guide wire core 21.

The heat generating portion 22 is a layer of heat conducting medium. The heating portion 22 and the guide wire core 21 may be formed integrally, and the heating portion 22 may be bonded or welded to the guide wire core 21.

The heating part 22 protrudes from the outer peripheral wall of the guide wire core 21 along the radial direction to increase the heating area, so as to further improve the capturing capability of thrombus. Of course, the heat generating portion 22 may not protrude from the outer peripheral wall of the guide core 21.

The radial width of the heating portion 22 gradually increases from the two ends to the middle, so that a structure with small sizes at the two ends and a large size at the middle is formed, and the flow resistance of the heating portion 22 to the blood flow is reduced after the blood flow channel is opened. Specifically, the heat generating portion 22 may have an ellipsoidal spherical structure, and both ends of the ellipsoidal spherical structure are arranged corresponding to the proximal end and the distal end of the thrombectomy support 1g, respectively. The outer peripheral wall of the heating part 22 is streamline with smooth transition, that is, the proximal end and the distal end of the heating part 22 are both streamline design.

In the thrombectomy support 1g of the present embodiment, the heat generating portion 22 may be disposed in the rigid unit 11 or the flexible unit 12. The heat generating part 22 may be provided in plural, and the plural heat generating parts 22 are arranged at intervals.

Preferably, the heat generating element 22 may be disposed corresponding to the rigid unit 11 so as to enhance the catching ability of a large thrombus falling in the space area between the adjacent two flexible units 12.

A ninth embodiment, see the structure shown in fig. 27.

The thrombectomy device 100h of the present embodiment is similar to the eighth embodiment in structure, except that the traction guidewire 2h is designed differently.

The traction wire 2h of the present embodiment includes a wire core 21h, a heat generating portion 22h provided on the wire core 21h, and an elastic portion 24 provided on the wire core 21h and arranged at an interval from the heat generating portion 22 h.

The elastic portion 24 is of a segment structure and is correspondingly disposed in the flexible unit 12. The heat generating portion 22h is correspondingly provided in the rigid unit 11.

The thrombectomy support 1h of the present embodiment further comprises a plurality of connecting rods 16. Both ends of the elastic part 24 are connected to the peripheral side wall of the thrombectomy support 1h through one or more connecting rods 16, respectively. That is, the inner end of each connecting rod 16 is connected to the end of the elastic portion 24, and the outer end of the connecting rod 16 may be connected to the circumferential side wall of the rigid unit 11 or the flexible unit 12, or to the connecting arm 13. The two ends of the elastic part 24 are fixed relative to the bolt-removing bracket 1h through the connecting rods 16, so that the elastic part 24 is aligned and limited in the corresponding flexible unit 12, and the heating parts 22h are correspondingly distributed in the rigid unit 11.

The elastic portion 24 may be in a stretched state with the thrombectomy stent 1h kept in a collapsed state. As shown in FIG. 27, the flexible unit 12 can self-expand when the thrombectomy stent 1h is released within the vessel. And when self-expanding and radially deployed, its axial dimension shortens. The restoring force of the elastic part 24 can assist the thrombus taking support 1h to expand, so that the thrombus taking support 1h can be quickly unfolded; and the length of the elastic portion 24 is shortened in synchronization with the axial dimension of the flexible unit 12 during the radial expansion of the flexible unit 12.

The connecting rod 16 can be extended and retracted along the radial direction of the bolt taking support 1h, such as a wave-shaped rod or an elastic expansion piece. When the thrombectomy stent 1h is expanded, the connecting rod 16 may be stretched. When the thrombectomy support 1h shrinks to be in a collapsed state, the connecting rod 16 can be compressed to facilitate the connecting rod 16 to be accommodated in the sheath 500 to maintain the collapsed state together with the thrombectomy support 1 h.

While the present invention has been described with reference to several exemplary embodiments, it is understood that the terminology used is intended to be in the nature of words of description and illustration, rather than of limitation. As the present invention may be embodied in several forms without departing from the spirit or essential characteristics thereof, it should also be understood that the above-described embodiments are not limited by any of the details of the foregoing description, but rather should be construed broadly within its spirit and scope as defined in the appended claims, and therefore all changes and modifications that fall within the meets and bounds of the claims, or equivalences of such meets and bounds are therefore intended to be embraced by the appended claims.

Claims (22)

1. A thrombus removal support is characterized by comprising rigid units and flexible units which are arranged in a linear manner and are alternately connected;

the rigid unit and the flexible unit are both tubular structures which can be compressed and expanded radially;

the flexible unit is more susceptible to buckling deformation than the rigid unit when subjected to equal radial forces.

2. The embolectomy stent of claim 1, wherein the maximum radial dimension of the flexible element is greater than the radial dimension of the rigid element in the naturally expanded state.

3. The embolectomy support of claim 2, wherein the flexible unit comprises a connector and a wave ring which are axially connected in correspondence; the connector is positioned on the distal side of the wave ring;

each wave-shaped ring is provided with wave crests and wave troughs which are staggered along the circumferential direction; and part of wave crests of the wave ring are connected with the near end of the connecting piece, and part of wave crests of the wave ring are suspended.

4. The embolectomy support of claim 3 wherein the wave-shaped ring has wave crests correspondingly connected to the connecting members and wave crests suspended in the air at staggered intervals.

5. The embolectomy support of claim 4, wherein the connecting member comprises a plurality of circumferentially spaced V-shaped rods, the V-shaped rods being bent in a V-shape;

the vertex of the V-shaped rod is a near end and is connected with the wave crest of the wave-shaped ring;

two ends of the V-shaped rod opposite to the vertex of the V-shaped rod are far ends, and the two far ends of the V-shaped rod are used for being connected with the rigid unit or the wave trough of another wave-shaped ring.

6. The embolectomy support of claim 2 wherein the flexible member is more easily axially compressed than the rigid member when subjected to an equivalent axial force; and the radial dimension of the flexible unit increases synchronously when the flexible unit is axially compressed.

7. The embolectomy support of claim 6, wherein the flexible unit comprises a plurality of co-helically wound helical rods arranged in a circumferentially spaced arrangement;

and two ends of the screw rod are respectively connected with one rigid unit.

8. The embolectomy stent of claim 7, wherein the winding angle from one end of the helical rod to the other end of the helical rod is in the range of 0-360 °.

9. The embolectomy support of claim 7, wherein the screw rod comprises a first wound section and a second wound section which are connected at one end, and the first wound section and the second wound section are both spirally wound;

in a natural expansion state, the distance from the first winding section to the central axis of the flexible unit is gradually reduced in the direction away from the second winding section; the distance from the second winding section to the central shaft of the flexible unit is gradually reduced in the direction away from the first winding section; the connection position of the first winding section and the second winding section is the outermost side of the flexible unit in the radial direction.

10. The embolectomy support of claim 2, further comprising a connecting arm, wherein the rigid unit and the flexible unit are connected by the connecting arm, and the connecting arm is rod-shaped.

11. The embolectomy support of claim 10 wherein the connecting arm is provided in a plurality, the plurality of connecting arms being distributed along the circumference of the rigid unit.

12. The embolectomy support of any of claims 1-11, wherein the proximal-most end and distal-most end of the embolectomy support are both the rigid unit.

13. The embolectomy stent of any of claims 1-11, wherein the maximum radial dimension of the plurality of flexible elements in the embolectomy stent sequentially increases in a proximal to distal direction in a naturally expanded state.

14. The embolectomy support of any of claims 1-11 wherein for a collection of rigid units disposed between adjacent two of the flexible units, the axial lengths of the rigid units in the collection become successively smaller in a direction from the proximal end to the distal end of the embolectomy support.

15. The embolectomy support of any of claims 1-11 wherein for a collection of rigid elements disposed between adjacent two of the flexible elements, the radial dimension of each of the rigid elements in the collection becomes progressively larger in the proximal-to-distal direction.

16. An embolectomy device comprising an embolectomy stent as defined in any of claims 1-15 and a pull guidewire attached to the embolectomy stent.

17. The embolectomy device of claim 16, further comprising a distal tube and a proximal tube;

the most distal end of the thrombus removal support is converged and connected on the distal tube; the proximal end of the thrombus removal support is connected with the proximal tube in a converging manner.

18. The embolectomy device of claim 17, wherein the distal end of the pull guidewire is attached to the proximal tube.

19. The embolectomy device of claim 17, wherein the proximal tube is a hollow tube; the traction guide wire penetrates through the proximal tube and sequentially penetrates through the rigid unit and the flexible unit, and the distal end of the traction guide wire is connected with the distal tube.

20. The embolectomy device of claim 19 wherein the distal tube is a hollow tube and the distal end of the pull wire exits the distal tube and is captured at the distal end of the distal tube.

21. The embolectomy device of claim 19, wherein the pull guidewire is provided with a heating portion, and the heating portion is correspondingly arranged in the rigid unit or the flexible unit;

the pull wire may be electrically connected to an external power source; in the energized state, the heat generating portion is capable of generating heat.

22. An embolectomy system comprising an embolectomy device of any of claims 16-21, a pusher, a loading sheath and a microcatheter;

the push rod is connected with the near end of the thrombus taking support and is used for pushing and pulling the thrombus taking support;

the loading sheath is used for accommodating the embolectomy device in a compressed state;

the micro-catheter is used for being communicated with the loading sheath, and the lumen in the micro-catheter is used for conveying the thrombus removal device.

Images