CN213724939U

CN213724939U - Microwave extraction device for podophyllotoxin extraction

Info

Publication number: CN213724939U
Application number: CN202022110948.6U
Authority: CN
Inventors: 王玉斌; 黄慧莲; 梁永红; 钦松
Original assignee: Nanjing Yiteng Pharmaceutical Research Institute Co Ltd
Current assignee: Nanjing Yiteng Pharmaceutical Research Institute Co Ltd
Priority date: 2020-09-24
Filing date: 2020-09-24
Publication date: 2021-07-20
Anticipated expiration: 2030-09-24

Abstract

The utility model relates to a podophyllotoxin draws uses microwave extraction device, including the extraction jar, extraction jar both sides are equipped with microwave generator, extraction tank deck portion one side is equipped with the storage tank, the storage tank passes through inlet pipe and the inside intercommunication of extraction jar, extraction tank deck portion opposite side is equipped with the inlet, the extraction tank bottoms portion is equipped with the filter screen, the filter screen bottom is connected with hydrops case, hydrops bottom of the case intermediate position is equipped with the liquid outlet, extraction tank deck portion bottom, filter screen one side are equipped with the slag notch, hydrops bottom of the case both sides are equipped with the landing leg. Carry out breakage and stirring to the material through stirring vane and the broken blade that sets up the rotation, set up the scraper blade of revolution simultaneously, will adhere to the residual material on the extraction jar inner wall and scrape down, continue stirring and breakage, make solvent and material intensive mixing, improve extraction efficiency.

Description

Microwave extraction device for podophyllotoxin extraction

Technical Field

The utility model relates to a microwave extraction technical field especially relates to a podophyllotoxin draws and uses microwave extraction device.

Background

Podophyllotoxin is a lignan-type antitumor component extracted from root and stem of Podophyllum peltatum (also called as "desmin") belonging to Podophyllum of berberidaceae. Podophyllotoxin can effectively inhibit herpesvirus, inhibit mitosis in metaphase of cell, and can be used for treating toxic diseases. When the existing microwave extraction device is used for adding a medicament for stirring and extracting in material crushing, the stirring is not uniform and insufficient, and the solvent and the material are not sufficiently mixed, so that the extraction efficiency is low.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the technical problem of providing a microwave extraction device for extracting podophyllotoxin, solving the problem mentioned in the above-mentioned background art.

In order to solve the technical problem, the microwave extraction device for extracting podophyllotoxin of the utility model comprises an extraction tank, wherein microwave generators are arranged at two sides of the extraction tank, a storage tank is arranged at one side of the top of the extraction tank, the storage tank is communicated with the inside of the extraction tank through a feed pipe, and a liquid inlet is arranged at the other side of the top of the extraction tank; a driving motor is fixed on the top of the extraction tank through a rack, the output end of the driving motor is fixedly connected with a stirring main shaft, the other end of the stirring main shaft is fixed at the center of the bottom of the extraction tank, the upper end of the stirring main shaft is respectively connected with a first driven shaft and a second driven shaft through fixing rods, the first driven shaft and the second driven shaft are respectively parallel to the stirring main shaft, a first scraper blade is arranged on the first driven shaft, and a second scraper blade is arranged on the second driven shaft; the stirring main shaft is also fixedly provided with a driving box, the driving box is positioned below the fixed rod, a driving assembly is arranged in the driving box, one end of the driving assembly is connected with a crushing shaft, the crushing shaft rotates under the action of the driving assembly, a crushing blade is arranged on the crushing shaft, and the stirring main shaft is provided with a stirring blade; the extraction tank bottom is equipped with the filter screen, the filter screen bottom is connected with hydrops case, hydrops bottom intermediate position is equipped with the liquid outlet, extraction tank side bottom, filter screen one side are equipped with the slag notch, hydrops bottom both sides are equipped with the landing leg.

Carry out breakage and stirring to the material through stirring vane and the broken blade that sets up the rotation, set up the scraper blade of revolution simultaneously, will adhere to the residual material on the extraction jar inner wall and scrape down, continue stirring and breakage, make solvent and material intensive mixing, improve extraction efficiency.

As an improvement of the utility model, the drive assembly includes driving gear and two driven gear, the driving gear is fixed on the stirring main shaft, driven gear passes through the fixed axle and fixes respectively in the driving gear both sides, driven gear and driving gear meshing, broken axle is fixed at the driven gear lower extreme to it is located inside the extraction jar to pass the drive case. Through setting up driving gear and driven gear meshing, make driving spindle, crushing axle all carry out the rotation under driving motor drives.

As an improvement of the utility model, the stirring blade is arranged at an interval with the crushing blade. Ensuring that the stirring blades interact with the crushing blades without interference.

As an improvement of the utility model, the bottom surface is laminated in scraper blade first base and the extraction jar, the laminating of scraper blade second base and extraction jar inside wall. The first scraper is used for scraping materials on the inner bottom surface of the extraction tank, and the second scraper is used for scraping materials on the inner side wall of the extraction tank, so that residues on the extraction tank are avoided.

As an improvement of the utility model, an inclination is formed between the bottom surface in a scraper blade base and the extraction jar, an inclination is formed between two bases of scraper blade and the extraction jar inside wall.

As an improvement of the utility model, the solvent dropped into by the liquid inlet is ethyl acetate.

Compared with the prior art, the utility model has the advantages that 1) the materials are crushed and evenly stirred by the self-rotating stirring blades and the crushing blades, and the residual materials attached to the inner wall of the extraction tank are scraped by the revolution scraper blade, so that the stirring and crushing are continued, the solvent is fully mixed with the materials, and the extraction efficiency is improved; 2) a driving gear is meshed with a driven gear, so that the driving main shaft and the crushing shaft are driven by a driving motor to rotate; 3) stirring vane and broken blade interval set up, and stirring vane and broken blade interact guarantee that the material is broken abundant, the stirring, can not produce mutual interference simultaneously.

Drawings

FIG. 1 is a schematic structural view of a microwave extraction apparatus for extracting podophyllotoxin of the present invention;

fig. 2 is a schematic structural diagram of a driving assembly of the present invention;

FIG. 3 is a schematic structural diagram of a first scraper, a second scraper and an extraction tank when the stirring main shaft rotates along the direction B;

in the figure: 1. an extraction tank; 2. a microwave generator; 3. a material storage tank; 4. a drive motor; 5. a stirring main shaft; 51. a first moving shaft; 52. a second moving shaft; 53. fixing the rod; 54. a stirring blade; 61. a first scraper plate; 62. a second scraper plate; 7. a drive box; 81. a driving gear; 82. a driven gear; 83. a fixed shaft; 9. a crushing shaft; 91. crushing the blade; 10. a filter screen; 11. a liquid accumulation box; 12. a liquid accumulation box; 13. a slag outlet; 14. a support leg; 15. and (4) a liquid inlet.

The specific implementation mode is as follows:

for the purpose of enhancing the understanding of the present invention, the following detailed description is made with reference to the accompanying drawings.

Example 1: referring to fig. 1-3, a microwave extraction device for podophyllotoxin extraction, includes extraction jar 1, and extraction jar 1 both sides are equipped with microwave generator 2, and extraction jar 1 top one side is equipped with storage tank 3, and storage tank 3 passes through inlet pipe 31 and the inside intercommunication of extraction jar 1, and extraction jar 1 top opposite side is equipped with inlet 15. Extract 1 top intermediate position of jar and be equipped with driving motor 4, driving motor 4 is fixed with the extraction jar through frame 41, driving motor 4's output is connected with the stirring main shaft 5 of vertical setting, the 5 other ends of stirring main shaft are fixed in 1 bottom center department of extraction jar, the position that is close to the extraction jar top on the stirring main shaft 5, be connected with driven shaft one 51 and driven shaft two 52 respectively through dead lever 53, driven shaft one 51 and driven shaft two 52 are parallel with stirring main shaft 5 respectively, be equipped with scraper blade one 61 on the driven shaft one 51, be equipped with scraper blade two 62 on the driven shaft two 52. A driving box 7 is further fixed on the stirring main shaft 5, the driving box 7 is located below the fixing rod 53, a driving assembly is arranged in the driving box 7, one end of the driving assembly is connected with a crushing shaft 9, the crushing shaft 9 rotates under the action of the driving assembly, a crushing blade 91 is arranged on the crushing shaft 9, and a stirring blade 54 is arranged on the stirring main shaft 5; extraction jar 1 bottom is equipped with filter screen 10, and filter screen 10 bottom is connected with

hydrops case

11, and 11 bottom intermediate positions of hydrops case are equipped with

liquid outlet

12, and 1 side bottom of extraction jar, filter screen 10 one side are equipped with

slag notch

13, and 11 bottom both sides of hydrops case are equipped with landing leg 14 and are used for supporting extraction device.

The driving assembly comprises a driving gear 81 and two driven gears 82, the driving gear 81 is fixed on the stirring main shaft 5, the driven gears 82 are respectively fixed on two sides of the driving gear 81 through a fixing shaft 83, the driven gears 82 are meshed with the driving gear 81, and the crushing shaft 9 is fixed at the lower end of the driven gears 82 and penetrates through the driving box 7 to be located inside the extraction tank 1. Through setting up driving gear and driven gear meshing, make driving spindle, crushing axle all carry out the rotation under driving motor drives.

The stirring vanes 54 are provided at intervals from the crushing blades 91. Ensuring that the stirring blades interact with the crushing blades without interference.

The bottom edge of the first scraper 61 is attached to the inner bottom surface of the extraction tank 1, and the bottom edge of the second scraper 62 is attached to the inner side wall of the extraction tank 1. The first scraper is used for scraping materials on the inner bottom surface of the extraction tank, and the second scraper is used for scraping materials on the inner side wall of the extraction tank, so that residues on the extraction tank are avoided.

An inclined angle is formed between the bottom edge of the first scraper 61 and the inner bottom surface of the extraction tank 1, and an inclined angle is formed between the bottom edge of the second scraper 62 and the inner side wall of the extraction tank 1.

The solvent dropped from the liquid inlet 15 is ethyl acetate.

The working process is as follows: referring to fig. 1-3, during the use, the raw materials in the storage tank gets into the extraction jar through the inlet pipe, drips into the solvent from the inlet, then starts driving motor, and stirring vane and crushing blade rotation stir the material breakage, and scraper blade one and scraper blade two revolute under the driven shaft drives simultaneously, scrape the material to extraction jar inside wall and interior bottom, guarantee material and solvent intensive mixing stirring. The mixed solution is filtered by a filter screen, enters a liquid accumulation box and is finally discharged through a liquid outlet. The material residue is discharged out of the extraction tank through a slag outlet.

Finally, it should be noted that: the technical means disclosed by the scheme of the present invention is not limited to the technical means disclosed by the above embodiments, but also includes the technical scheme formed by the arbitrary combination of the above technical features. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, several improvements and modifications can be made, and these improvements and modifications are also considered as the protection scope of the present invention.

Claims

1. The utility model provides a microwave extraction device is used in podophyllotoxin extraction which characterized in that: the microwave extraction device comprises an extraction tank (1), wherein microwave generators (2) are arranged on two sides of the extraction tank (1), a storage tank (3) is arranged on one side of the top of the extraction tank (1), the storage tank (3) is communicated with the interior of the extraction tank (1) through a feeding pipe (31), and a liquid inlet (15) is arranged on the other side of the top of the extraction tank (1); the top of the extraction tank (1) is fixedly provided with a driving motor (4) through a rack (41), the output end of the driving motor (4) is fixedly connected with a stirring main shaft (5), the other end of the stirring main shaft (5) is fixed at the center of the bottom of the extraction tank (1), the upper end of the stirring main shaft (5) is respectively connected with a driven shaft I (51) and a driven shaft II (52) through a fixing rod (53), the driven shaft I (51) and the driven shaft II (52) are respectively parallel to the stirring main shaft (5), a scraper I (61) is arranged on the driven shaft I (51), and a scraper II (62) is arranged on the driven shaft II (52); a driving box (7) is further fixed on the stirring main shaft (5), the driving box (7) is located below the fixing rod (53), a driving assembly is arranged in the driving box (7), one end of the driving assembly is connected with a crushing shaft (9), the crushing shaft (9) rotates under the action of the driving assembly, a crushing blade (91) is arranged on the crushing shaft (9), and a stirring blade (54) is arranged on the stirring main shaft (5); the bottom of the extraction tank (1) is provided with a filter screen (10), the bottom of the filter screen (10) is connected with a liquid accumulation box (11), the middle position of the bottom of the liquid accumulation box (11) is provided with a liquid outlet (12), the bottom of the side surface of the extraction tank (1) and one side of the filter screen (10) are provided with a slag outlet (13), and two sides of the bottom of the liquid accumulation box (11) are provided with supporting legs (14).

2. The microwave extraction device for podophyllotoxin extraction according to claim 1, wherein: the driving assembly comprises a driving gear (81) and two driven gears (82), the driving gear (81) is fixed on the stirring main shaft (5), the driven gears (82) are fixed on two sides of the driving gear (81) through fixing shafts (83), the driven gears (82) are meshed with the driving gear (81), the crushing shaft (9) is fixed at the lower end of the driven gears (82) and penetrates through the driving box (7) to be located inside the extraction tank (1).

3. The microwave extraction device for podophyllotoxin extraction according to claim 1, wherein: the stirring blades (54) and the crushing blades (91) are arranged at intervals.

4. The microwave extraction device for podophyllotoxin extraction according to claim 1, wherein: the bottom edge of the first scraper (61) is attached to the inner bottom surface of the extraction tank (1), and the bottom edge of the second scraper (62) is attached to the inner side wall of the extraction tank (1).

5. The microwave extraction device for podophyllotoxin extraction according to claim 1, wherein: an inclined angle is formed between the bottom edge of the first scraper (61) and the inner bottom surface of the extraction tank (1), and an inclined angle is formed between the bottom edge of the second scraper (62) and the inner side wall of the extraction tank (1).

6. The microwave extraction device for podophyllotoxin extraction according to claim 1, wherein: the solvent dropped from the liquid inlet (15) is ethyl acetate.