CN213432510U - Fecal bacteria transplantation aseptic drug delivery device for colon placement - Google Patents
Fecal bacteria transplantation aseptic drug delivery device for colon placement Download PDFInfo
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- CN213432510U CN213432510U CN202020537025.6U CN202020537025U CN213432510U CN 213432510 U CN213432510 U CN 213432510U CN 202020537025 U CN202020537025 U CN 202020537025U CN 213432510 U CN213432510 U CN 213432510U
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- drug delivery
- colon
- fecal bacteria
- delivery device
- tube
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- 238000012377 drug delivery Methods 0.000 title claims abstract description 72
- 241000894006 Bacteria Species 0.000 title claims abstract description 57
- 230000002550 fecal effect Effects 0.000 title claims abstract description 57
- 238000002054 transplantation Methods 0.000 title claims description 54
- 210000001072 colon Anatomy 0.000 title claims description 52
- 239000007788 liquid Substances 0.000 claims abstract description 44
- 230000001050 lubricating effect Effects 0.000 claims abstract description 36
- 238000004806 packaging method and process Methods 0.000 claims abstract description 13
- 238000003860 storage Methods 0.000 claims abstract description 13
- 239000003814 drug Substances 0.000 claims description 24
- 239000000463 material Substances 0.000 claims description 5
- 239000000314 lubricant Substances 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 239000012530 fluid Substances 0.000 abstract 1
- 238000005461 lubrication Methods 0.000 description 8
- 239000005662 Paraffin oil Substances 0.000 description 7
- 229940079593 drug Drugs 0.000 description 6
- 241001391944 Commicarpus scandens Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 210000001035 gastrointestinal tract Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000000474 nursing effect Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 210000000436 anus Anatomy 0.000 description 2
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000020805 dietary restrictions Nutrition 0.000 description 2
- 238000001647 drug administration Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000010687 lubricating oil Substances 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 206010003805 Autism Diseases 0.000 description 1
- 208000020706 Autistic disease Diseases 0.000 description 1
- 208000031729 Bacteremia Diseases 0.000 description 1
- 208000037384 Clostridium Infections Diseases 0.000 description 1
- 206010009657 Clostridium difficile colitis Diseases 0.000 description 1
- 206010054236 Clostridium difficile infection Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000792859 Enema Species 0.000 description 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940095399 enema Drugs 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 208000007386 hepatic encephalopathy Diseases 0.000 description 1
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- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
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- 230000009885 systemic effect Effects 0.000 description 1
- 210000003384 transverse colon Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
本实用新型公开了结肠放置的粪菌移植无菌给药装置，包括置物托盘、设于所述置物托盘内的给药管和环设于所述给药管上的润滑组件以及以中单；所述润滑组件为中空的筒状，所述给药管从起中空的容纳腔处穿过且所述润滑组件设于所述给药管的靠近进液口的一侧；所述润滑组件内用于容纳医用润滑液；还包括一包装袋，所述置物托盘以及其内容纳物均密封置于该包装袋内。本实用新型提供了结肠放置的粪菌移植无菌给药装置，其不仅提供了专用的给药管同时为该给药管提供专门的润滑组件，有效提高医护人员的工作效率。
The utility model discloses a colon-placed fecal bacteria transplant aseptic drug delivery device, which comprises a storage tray, a drug delivery tube arranged in the storage tray, a lubricating component annularly arranged on the drug delivery tube, and a middle order; The lubricating component is in the shape of a hollow cylinder, the drug delivery tube passes through the hollow accommodating cavity, and the lubricating component is arranged on the side of the drug delivery tube close to the liquid inlet; inside the lubricating component It is used for accommodating medical lubricating fluid; it also includes a packaging bag, and the storage tray and its contents are sealed and placed in the packaging bag. The utility model provides a colon-placed fecal bacteria transplant aseptic drug delivery device, which not only provides a dedicated drug delivery tube but also provides a special lubricating component for the drug delivery tube, thereby effectively improving the working efficiency of medical staff.
Description
Technical Field
The utility model relates to the technical field of medical supplies, in particular to a fecal bacteria transplantation aseptic drug delivery device for colon placement.
Background
The coprophila transplantation technology is already mature and applied to the treatment of recurrent clostridium difficile infection and inflammatory bowel disease, and is gradually applied to the treatment of other systemic diseases (such as autism, alzheimer disease, hepatic encephalopathy, tumors and the like) except intestinal tracts.
At present, the administration mode of the fresh fecal bacteria liquid is mainly to place a drug tube through a colonoscope or a nasogastric tube, use and clamp the drug tube on the mucosa of the digestive tract for temporary fixation, and can continuously administer the drug for several days. The mode needs to place an enteroscope or a gastroscope in a special digestive department, has poor tolerance of a patient, and is easy to damage digestive tract mucosa due to harmonious clips. In particular, the transnasal gastric tube is susceptible to aspiration (aspiration has been reported to cause pneumonia and bacteremia, and eventually death). Meanwhile, in order to maintain the treatment for a period of time, the administration tube needs to be kept for a longer time, the requirement on the diet of a patient is high, and the eating of solid food is generally limited, so that the nutritional state of the patient is influenced. In addition, the placement of the gastroscope, the enteroscope and the harmonious clamp also obviously increases the economic burden of the patient and influences the feasibility of treatment.
Therefore, designing a simple, efficient and economical fecal bacteria transplantation sterile administration tube placed in the colon is an urgent clinical problem to be solved; the administration tube has similar effect with the anal tube, and paraffin oil is required to be smeared for sufficient lubrication when the administration tube is used, at present, medical personnel often need to open the independently packaged paraffin oil and then dip the paraffin oil with a cotton swab or gauze to wipe the administration tube, so that the surface of the anal tube is lubricated;
above-mentioned operation is in the actual operation in-process, and not only waste time and energy relatively, makes paraffin oil pollute the mesa moreover easily, has increased medical personnel's working strength.
For the above reasons, in order to ensure the normal progress of fecal bacteria transplantation, it is urgently needed to design a fecal bacteria transplantation sterile drug delivery device for colon placement.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to overcome the shortcoming that exists among the prior art, provide the aseptic device of dosing of coprophilous bacterium transplantation that the colon was placed, it not only provides dedicated dosing pipe and provides special lubricated subassembly for this dosing pipe simultaneously, effectively improves medical personnel's work efficiency.
In order to achieve the above object, the present invention mainly provides the following technical solutions:
a fecal bacteria transplantation aseptic drug delivery device placed in the colon,
comprises a placement tray, a drug delivery pipe arranged in the placement tray, a lubricating component arranged on the drug delivery pipe in a ring mode, and a middle sheet;
the lubricating component is in a hollow cylinder shape, the administration tube penetrates through the hollow accommodating cavity from the beginning, and the lubricating component is arranged on one side of the administration tube close to the liquid inlet; the lubricating component is used for containing medical lubricating liquid;
the storage tray and the contents in the storage tray are sealed and arranged in the packaging bag.
The fecal bacteria transplantation sterile drug delivery device placed in the colon is characterized in that the lubricating component comprises an outer wall and an inner wall, the outer wall of the lubricating component is made of a soft silica gel pad, and the inner wall of the lubricating component is composed of a film provided with a plurality of easy-to-break lines;
the film is in a tight state and is rapidly cracked by external force extrusion.
The sterile administration device for colon-specific fecal bacteria transplantation is characterized in that 1 to 2 lubricating assemblies are arranged adjacently.
The fecal bacteria transplantation sterile drug delivery device for colon placement, wherein the drug delivery tube is a tube body with the length of 80cm and the inner diameter of 0.5 cm; the device comprises an outer pipe body, a switch valve and an inner pipe body from left to right in sequence;
the end part of the outer tube body is provided with a liquid inlet interface connected with a liquid outlet of the syringe;
the liquid outlet end of the inner tube body is provided with a medicine outlet hole; the liquid outlet end is communicated with the administration tube.
The fecal bacteria transplantation sterile drug delivery device for colon placement is characterized in that the drug outlet hole is arranged in a position interval of 4cm from the head end of the inner tube body;
the medicine outlet holes are distributed at the liquid outlet end in a staggered way, and the number of the medicine outlet holes is 6;
the diameter of the medicine outlet hole is 0.3 cm.
The fecal bacteria transplantation sterile drug delivery device for colon placement is characterized in that the switch valve is a one-way valve, and the distance from the liquid inlet port is 3 cm.
The fecal bacteria transplantation sterile drug delivery device for colon placement is characterized in that a scale value is arranged on the drug delivery pipe; the scale of the liquid outlet end is 0.0cm, the scale of the liquid inlet end is 80.0cm, and the scale interval is 1.0 cm.
The fecal bacteria transplantation sterile drug delivery device for colon placement is characterized in that the drug delivery pipe is made of PCV material.
The fecal bacteria transplantation sterile drug delivery device for colon placement is characterized in that a film packaging bag is sleeved on the drug delivery tube.
Compared with the prior art, the utility model discloses the beneficial effect who produces mainly embodies:
the sterile administration device for fecal bacteria transplantation in colon placement is provided, can be applied to the sterile administration of fecal bacteria transplantation in colon placement, and is uniformly placed by arranging the administration tube, the lubricating component and the middle sheet which are specially applied to the sterile administration device, thereby being convenient for medical staff to use;
the structure design of the administration tube of the fecal bacteria transplantation aseptic administration device for placing the colon of the utility model is in accordance with the operation of the uniform fecal bacteria transplantation aseptic administration, thereby avoiding the application of gastroscope or colonoscope; avoid the use of temporarily fixed harmonic clamps; avoid dietary restriction for patients; it is a simple, efficient and economical sterile administration for fecal bacteria transplantation;
the fecal bacteria transplantation aseptic drug delivery device for colon placement of the utility model is provided with the lubricating component, which can lubricate the drug delivery tube, thereby effectively avoiding the problems generated during the lubrication in the prior art;
the foregoing description is only an overview of the technical solutions of the present invention, and in order to clearly understand the technical means of the present invention and implement the technical means according to the content of the description, the following detailed description of the preferred embodiments of the present invention is given with reference to the accompanying drawings.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic structural view of a fecal bacteria transplantation aseptic drug delivery device for colon placement according to the present invention;
FIG. 2 is a first schematic structural view of the drug delivery tube for placing colon according to the present invention;
FIG. 3 is a second schematic structural view of the drug delivery tube for placing colon according to the present invention;
FIG. 4 is a schematic view of the lubrication assembly of the present invention;
fig. 5 is a cross-sectional view of the lubrication assembly of the present invention;
description of reference numerals:
1. put thing tray 2, administer medicine pipe 3, lubricating component
4. Single sheet 5, packaging bag 6 and film packaging bag
21. Outer tube 22, switch valve 23, inner tube
24. Liquid inlet interface 25, medicine outlet hole 26 and liquid outlet end
27. Scale value
31. Outer wall 32, inner wall 33, frangible line
Detailed Description
To further illustrate the technical means and effects of the present invention for achieving the intended purpose of the present invention, the following detailed description will be given with reference to the accompanying drawings and preferred embodiments of the present invention for the specific embodiments, structures, features and effects of the device for sterile administration of fecal bacteria transplantation for colon placement.
As shown in fig. 1-5, the device for sterile administration of fecal bacteria transplantation placed in colon of the present invention comprises:
comprises a placement tray 1, an administration tube 2 arranged in the placement tray 1, a lubricating component 3 annularly arranged on the administration tube 2 and a middle sheet 4;
the lubricating component 3 is in a hollow cylinder shape, the administration tube 2 penetrates through the hollow accommodating cavity from the beginning, and the lubricating component 3 is arranged on one side of the administration tube 2 close to the liquid inlet; the lubricating component 3 is used for containing medical lubricating liquid;
the storage tray comprises a storage tray body 1 and a packaging bag 5, wherein the storage tray body 1 and the contents in the storage tray body are hermetically arranged in the packaging bag 5.
The fecal bacteria transplantation aseptic drug delivery device for colon placement of the embodiment of the application comprises the following components in the using process:
the medical staff firstly selects the administration tube 2 with proper length according to the operation position of the patient so as to determine the model of the administration device, and when the administration device is needed to be used in the operation, firstly, the administration tube 2 is lubricated as follows:
the medical staff firstly opens the packaging bag 5, takes out the storage tray 1 and then opens the opening of the film packaging bag 6 coated on the administration tube 2; then, one hand of the medical staff holds the liquid inlet end of the administration tube 2, the other hand pinches the lubricating component 3, the paraffin oil flows out when the easy-cracking line 33 is cracked, and the administration tube 2 is slowly drawn out to coat the paraffin oil on the side wall of the administration tube; because the length of the administration tube 2 is longer, when the administration tube 2 is stretched out by half, the second lubricating component 3 can be pinched by the same method to realize the same operation and fully lubricate the administration tube 2;
after the preoperative preparation work is finished, when in operation, the specific use is as follows:
1) the patient defecates 10 minutes in advance (enema can be used), orders the left lateral position, and the caregiver opens the bag 5;
2) taking out the middle sheet 4, and laying the middle sheet 4 under the hip of the patient;
3) the administration tube 2 is fully infiltrated by the method;
4) the permeability of the administration tube 2 is checked by the nursing staff, the administration tube 2 can be flushed by sterile physiological saline, and the permeability is good without resistance; checking the function of the on-off valve 22 at the same time;
5) the nursing staff slowly inserts the administration tube 2 through the anus of the patient, the optimal depth is 65-70cm, and the transverse colon position is reached;
6) the nursing staff is connected with the injector filled with the fresh fecal bacteria liquid through the administration end, the switch valve 22 is closed at an interval, and the valve is opened after the connection is finished to continue the injection;
7) closing the valve, slowly pulling out the administration tube 2, ordering the patient to be in the lower and higher position, lying on the side for 30 minutes, and changing the position to lie on the side for 30 minutes.
As shown in fig. 4 and 5, the sterile administration device for fecal bacteria transplantation placed in colon of the present invention comprises a lubricating component 3 comprising an outer wall 31 and an inner wall 32, wherein the outer wall 31 is made of a soft silica gel pad, and the inner wall 32 is composed of a film provided with a plurality of easy-to-break lines 33; the film is in a tight state and is rapidly cracked by external force extrusion.
The fecal bacteria transplantation aseptic drug delivery device for colon placement of the embodiment of the application, wherein the lubricating component 3 is cylindrical, the drug delivery tube 2 can pass through the accommodating cavity in the center of the drug delivery tube, when in use, a user can squeeze the easy-to-break line 33 on the inner wall 32 by force to break the easy-to-break line, so that the lubricating oil slowly overflows to lubricate the drug delivery tube 2;
it should be noted that, in order to ensure sufficient lubrication of the administration tube 2, the number of the easy-to-tear lines 33 is 3-4, and the medical staff strongly squeezes the easy-to-tear lines 33 on the inner wall 32 to know that the easy-to-tear lines 33 are cracked; in order to ensure that the administration tube 2 can be sufficiently lubricated, when the medical staff pulls the cover to administer the administration tube 2, the other hand holds the lubricating component 3 to properly and slowly apply force, so that the lubricating oil is slowly extruded, and meanwhile, the lubricating component 3 can be moderately rotated to sufficiently lubricate the administration tube 2.
As shown in figure 1, the fecal bacteria transplantation aseptic drug delivery device for colon placement of the utility model has 1-2 lubricating assemblies 3 which are adjacently arranged.
In the fecal bacteria transplantation aseptic drug delivery device for colon placement of the embodiment of the application, in order to improve the lubrication effect, if the length of the drug delivery tube 2 is longer, at least two lubrication components 3 can be designed to perform sufficient lubrication operation on the drug delivery tube.
As shown in fig. 2 and fig. 3, the fecal bacteria transplantation aseptic drug delivery device for colon placement of the present invention, the drug delivery tube 2 is a tube body with a length of 80cm and an inner diameter of 0.5 cm; which comprises an outer tube body 21, a switch valve 22 and an inner tube body 23 from left to right in sequence; the end part of the outer tube body 21 is provided with a liquid inlet interface 24 connected with a liquid outlet of the syringe; a liquid outlet end 26 of the inner tube body 23 is provided with a medicine outlet 25; the liquid outlet end 26 is communicated with the administration tube 2;
the sterile administration device for the fecal bacteria transplantation placed in the colon is provided with an administration tube 2, the length of which is 80cm in a preferred embodiment, and the inner diameter of which is 0.5 cm; the specification can be produced in different specifications according to the requirement;
as shown in fig. 3, in the sterile administration device for fecal bacteria transplantation placed in colon of the present invention, the drug outlet 25 is disposed in a position interval of 4cm from the head end of the inner tube 23; the medicine outlet holes 25 are distributed at the liquid outlet end 26 in a staggered way, and the number of the medicine outlet holes is 6; the diameter of the medicine outlet hole 25 is 0.3 cm.
In the fecal bacteria transplantation aseptic drug delivery device for colon placement of the embodiment of the application, the liquid outlet end 26 is communicated with the drug delivery pipe 2; the medicine liquid can enter smoothly, and the medicine outlet holes 25 which are distributed in a staggered manner are arranged to facilitate the quick discharge of the medicine liquid; the liquid outlet end 26 of the administration tube 2 is blunt, which is convenient for the placement.
As shown in fig. 3, the fecal bacteria transplantation aseptic drug delivery device for placing colon of the present invention, the switch valve 22 is a one-way valve, and the distance from the liquid inlet port 24 is 3 cm.
In the fecal bacteria transplantation aseptic drug delivery device for colon placement of the embodiment of the application, the switch valve 22 can be a common one-way valve at present, so that the on-off of the injection can be controlled conveniently.
As shown in fig. 3, the fecal bacteria transplantation aseptic drug delivery device for colon placement of the present invention, the drug delivery tube 2 is provided with a scale value 27; the scale of the liquid outlet end 26 is 0.0cm, the scale of the liquid inlet end is 80.0cm, and the scale interval is 1.0 cm.
The fecal bacteria transplantation aseptic drug delivery device placed in the colon is convenient to control the length of the inlet pipe by marking the scale value 27 on the pipe wall.
As shown in figure 2, the fecal bacteria transplantation aseptic drug delivery device for colon placement of the utility model is characterized in that the drug delivery tube 2 is made of PCV material, the hardness of the material is moderate, and the device can be inserted into the anus for use and can not damage the perianal area of the patient.
As shown in figure 1, the fecal bacteria transplantation aseptic drug administration device for placing colon of the utility model is provided with a film packing bag 6 on the drug administration tube 2.
The fecal bacteria transplantation sterile drug delivery device for colon placement in the embodiment of the application has moderate material hardness, and is suitable for being placed after being lubricated by paraffin oil under the condition of simple intestinal tract preparation; the liquid inlet end can be connected with a medical universal injector; the switch valve 22 is arranged to facilitate interval adjustment; the pipe wall is marked with scales, so that the length of the inlet pipe can be conveniently controlled; the medicine outlet end is smooth and has 4 liquid outlets, which is beneficial to liquid discharge; avoiding the use of gastroscopes or colonoscopes; avoid the use of temporarily fixed harmonic clamps; avoid dietary restriction for patients; is a simple, high-efficiency and economic fecal bacteria transplanting sterile administration tube 2.
The fecal bacteria transplantation aseptic drug delivery device for colon placement provided by the embodiment of the application has the following advantages:
1) the placement of a colonoscope or a gastroscope is avoided, the pain of a patient is reduced, and the treatment tolerance is increased;
2) the use of an endoscope and a harmonious clamp is avoided, the economic burden of a patient is reduced, and the compliance of the patient is increased;
3) the patient does not need diet restriction, malnutrition is avoided, and the safety of fresh bacterial liquid fecal strain transplantation is improved;
in summary, the sterile administration tube 2 of the present application can significantly improve the feasibility of fresh bacterial liquid fecal bacteria transplantation; in addition, the drug delivery system can be used as a basic tool for colon drug delivery and is used for releasing other drugs in the colon.
The present invention has been further described with reference to the embodiments, but the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.
Claims (9)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020537025.6U CN213432510U (en) | 2020-04-13 | 2020-04-13 | Fecal bacteria transplantation aseptic drug delivery device for colon placement |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020537025.6U CN213432510U (en) | 2020-04-13 | 2020-04-13 | Fecal bacteria transplantation aseptic drug delivery device for colon placement |
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| Publication Number | Publication Date |
|---|---|
| CN213432510U true CN213432510U (en) | 2021-06-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202020537025.6U Expired - Fee Related CN213432510U (en) | 2020-04-13 | 2020-04-13 | Fecal bacteria transplantation aseptic drug delivery device for colon placement |
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| CN (1) | CN213432510U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117224825A (en) * | 2023-09-04 | 2023-12-15 | 中国人民解放军空军军医大学 | Intestinal fungus transplanting and drug administration equipment for colon placement |
-
2020
- 2020-04-13 CN CN202020537025.6U patent/CN213432510U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117224825A (en) * | 2023-09-04 | 2023-12-15 | 中国人民解放军空军军医大学 | Intestinal fungus transplanting and drug administration equipment for colon placement |
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Granted publication date: 20210615 |