CN212631331U - A special infusion bag for immune cells - Google Patents
A special infusion bag for immune cells Download PDFInfo
- Publication number
- CN212631331U CN212631331U CN202020145388.5U CN202020145388U CN212631331U CN 212631331 U CN212631331 U CN 212631331U CN 202020145388 U CN202020145388 U CN 202020145388U CN 212631331 U CN212631331 U CN 212631331U
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- China
- Prior art keywords
- infusion
- pipe
- saline
- control valve
- cavity
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- Expired - Fee Related
Links
- 238000001802 infusion Methods 0.000 title claims abstract description 72
- 210000002865 immune cell Anatomy 0.000 title claims abstract description 32
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 41
- 239000011780 sodium chloride Substances 0.000 claims abstract description 38
- 210000004027 cell Anatomy 0.000 claims description 22
- 238000011010 flushing procedure Methods 0.000 abstract description 9
- 238000002360 preparation method Methods 0.000 abstract description 4
- 238000011109 contamination Methods 0.000 abstract 1
- 230000010354 integration Effects 0.000 abstract 1
- 239000012267 brine Substances 0.000 description 14
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 14
- 239000007788 liquid Substances 0.000 description 8
- 239000002504 physiological saline solution Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000003112 inhibitor Substances 0.000 description 4
- 239000012266 salt solution Substances 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000001363 autoimmune Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000002659 cell therapy Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Images
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
本实用新型提供了一种免疫细胞专用输液袋,包括输液袋本体，所述输液袋本体内部设有第一输液腔和第二输液腔，所述第一输液腔下方设有第一盐水管，第二输液腔下方设有第二盐水管、输液管和带有空气过滤器的空气管，所述第一盐水管通过第一软管控制连接第二盐水管，所述第一软管通过第二软管控制连接输液管，所述输液管通过第三软管连接输液针,本实用新型通过第一盐水管、第二盐水管和输液管能一体化的完成预冲、回输、再冲管，即保证了免疫细胞制剂的全量回输，更方便了护士的临床操作，很好地避免了因反复穿刺导致的污染风险，本实用新型结构新颖，操作简单，用途广泛，极易推广。
The utility model provides a special infusion bag for immune cells, comprising an infusion bag body, a first infusion cavity and a second infusion cavity are arranged inside the infusion bag body, and a first saline tube is arranged below the first infusion cavity, A second saline pipe, an infusion pipe and an air pipe with an air filter are arranged below the second infusion cavity, the first saline pipe is controlled and connected to the second saline pipe through a first hose, and the first hose is The second hose is controlled to connect the infusion tube, the infusion tube is connected to the infusion needle through the third hose, and the utility model can complete the pre-flushing, re-infusion and re-flushing through the integration of the first saline tube, the second saline tube and the infusion tube. The tube ensures full reinfusion of the immune cell preparation, which is more convenient for the clinical operation of nurses, and avoids the risk of contamination caused by repeated puncture.
Description
Technical Field
The utility model relates to an infusion technical field, concretely relates to special infusion bag of immune cell.
Background
Cell therapy has been increasingly applied to clinical applications, and autoimmune cell antitumor therapy and the like have been advanced and developed greatly. Suspending the prepared immune cells by using physiological saline and the like, and injecting the suspension into a 100-250 ml infusion bottle or a blood transfusion bag, which is a currently clinically common immune cell back transfusion mode. During the reinfusion, the blood transfusion device is firstly connected with the physiological saline flushing pipe, then the cell reinfusion bottle is connected to start reinfusion, after the cell fluid in the bottle is completely infused, 20ml of physiological saline is extracted by the syringe and is injected into the cell bottle, the cells attached to the bottle wall are flushed and then are infused into the body, finally, the physiological saline bottle is connected again, the cells in the blood transfusion device pipeline are completely flushed, the whole reinfusion process, the operations of pre-flushing, reinfusion, bottle flushing and pipe refilling are repeated (up to 5 times), and the risk of cell pollution and the workload of nurses are greatly increased.
The application number is CN201610346669.5 in the prior art, which is named as an immune cell preparation transfusion bag, and discloses the following contents of an upper administration end, an immune cell bag body, a lower administration end, a lower three-fork connection port, a silica gel soft plug, a first liquid stopping clamp, a lower cell pipeline, a saline pipe, a second liquid stopping clamp, a hanging hole, a saline short pipe, a third liquid stopping clamp, an upper three-fork connection port, an exhaust pipe, a needle head and a separable joint; the immune cell bag body is of a semi-elliptical structure, the volume of the immune cell bag body is 100-150 ml, and liquid level scales are marked on the immune cell bag body according to a scale mark unit of 20 ml; the upper administration end and the lower administration end are oppositely positioned at the edges of the upper and lower opposite ends of the immune cell bag body; the lower three-fork connecting port and the upper three-fork connecting port are respectively positioned at two opposite ends of the brine pipe; the silica gel soft plug is fixed at the lower end head of the brine pipe; the first liquid stopping clamp is positioned in the middle of the lower cell pipeline; one end of the lower cell pipeline is connected with the lower trident connecting port, and the other end of the lower cell pipeline is connected with the immune cell bag body; the saline pipe is located outside the immune cell bag body, the upper end of the saline pipe is connected with the saline short pipe through an upper three-fork connecting port, the lower end of the saline pipe is connected with the lower cell pipeline through a lower three-fork connecting port, and the length of the saline pipe is 15-35 cm; the second liquid stopping clamp is positioned in the middle of the brine pipe; the hanging hole is positioned at the upper end of the immune cell bag body and is integrated with the immune cell bag body into a whole; the third liquid stopping clamp is positioned in the middle of the saline short pipe; one end of the saline short pipe is connected with the upper three-fork connecting port, and the other end of the saline short pipe is connected with the immune cell bag body to form a saline passage; the needle head is positioned at the upper top end of the saline pipe; the exhaust pipe is fixedly arranged at the lower part of the needle head and is fixed on the brine pipe; the separable joint is positioned between the exhaust pipe and the needle head and is fixed on the saline pipe; the operation is complex and the effect is not ideal.
SUMMERY OF THE UTILITY MODEL
In order to solve the above problems, the utility model provides a transfusion bag special for immune cells.
The purpose of the utility model is realized with the following mode:
the utility model provides a special infusion bag of immune cell, includes the infusion bag body, infusion bag body inside is equipped with first infusion chamber and second infusion chamber, first infusion chamber below is equipped with first brine pipe, and second infusion chamber below is equipped with second brine pipe, transfer line and has air cleaner's air hose, first brine pipe is through first hose control connection second brine pipe, first hose is through second hose control connection transfer line, the transfer line passes through third hose connection transfusion needle.
The first transfusion cavity is a saline cavity, and the second transfusion cavity is a cell cavity.
The lower end of the first brine pipe is provided with a first control valve, the lower end of the second brine pipe is provided with a second control valve, the lower end of the infusion pipe is provided with a third control valve, the middle part of the second hose is provided with a fourth control valve, and the second hose is arranged below the third control valve.
The first control valve, the second control valve, the third control valve and the fourth control valve are all flow rate regulators.
An air pipe with an air filter is also arranged below the infusion tube.
The upper part of the first transfusion cavity is provided with a saline water inlet pipe with a saline water soft plug, the upper part of the second transfusion cavity is provided with a cell inlet pipe with a cell soft plug, and a hanging hole is further formed above the transfusion bag body.
Compared with the prior art, the utility model discloses a completion that first brine pipe, second brine pipe and transfer line can be integrated is dash in advance, is reinfused, is washed the pipe again, has guaranteed the total reinfused of immunocyte preparation promptly, has more made things convenient for nurse's clinical operation, has avoided the pollution risk because of puncturing repeatedly and leading to well, the utility model discloses novel structure, easy operation, the usage is extensive, very easily promotes.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
The infusion bag comprises an infusion bag body 1, a saline water inlet pipe 2, a cell inlet pipe 3, a hanging hole 4, a first infusion cavity 5, a second infusion cavity 6, a first saline water pipe 7, a second saline water pipe 8, an infusion pipe 9, an air pipe 10, a first control valve 11, a first hose 12, a second control valve 13, a fourth control valve 14, a third control valve 15, an infusion needle 16 and a second hose 17.
Detailed Description
As shown in the attached drawing 1, a special infusion bag for immune cells, including infusion bag body 1, 1 inside first infusion chamber 5 and the second infusion chamber 6 of being equipped with of infusion bag body, 5 below in first infusion chamber is equipped with first salt solution pipe 7, and 6 below in second infusion chamber are equipped with second salt solution pipe 8, transfer line 9 and have air cleaner's air hose 10, first salt solution pipe 7 is through first hose 12 control connection second salt solution pipe 8, first hose 12 is through second hose 17 control connection transfer line 9, transfer line 9 passes through third hose connection transfusion needle 16, and transfusion needle 16 is ordinary infusion bottle pjncture needle (plastics syringe needle or steel needle) that connects, and the third hose is medical transfer line 9.
The first transfusion cavity is a saline cavity, and the second transfusion cavity is a cell cavity.
The lower end of the first brine pipe 7 is provided with a first control valve 11, the lower end of the second brine pipe 8 is provided with a second control valve 13, the lower end of the infusion pipe 9 is provided with a third control valve 15, the middle of the second hose 17 is provided with a fourth control valve 14, the second hose 17 is arranged below the third control valve 15, and the first infusion cavity 5 and the second infusion cavity 6 are respectively controlled and used in a mixed mode through the first control valve 11, the second control valve 13, the third control valve 15 and the fourth control valve 14.
The first control valve 11, the second control valve 13, the third control valve 15 and the fourth control valve 14 are all flow rate regulators, and the specific structure is referred to as CN201420448928.1 and named as a transfusion system.
An air pipe 10 with an air filter is arranged below the infusion pipe 9.
The upper part of the first transfusion cavity 5 is provided with a saline inlet pipe 2 with a saline soft plug, the upper part of the second transfusion cavity 6 is provided with a cell inlet pipe 3 with a cell soft plug, and a hanging hole 4 is further arranged above the transfusion bag body 1.
The working process of the utility model is as follows: firstly, the physiological saline and the immune cell inhibitor enter a first transfusion cavity 5 and a second transfusion cavity 6 through a saline inlet pipe 2 and a cell inlet pipe 3 respectively, a second control valve 13 and a third control valve 15 are closed, a fourth control valve 14 is opened, the physiological saline in the first transfusion cavity 5 enters a human body through a second hose 17, then a first control valve 11, a second control valve 13 and a fourth control valve 14 are closed, the third control valve 15 is opened, the immune cell inhibitor in the second transfusion cavity 6 enters the human body through the second hose 17, then an air pipe 10 is blocked, (the air pipe 10 is squeezed by hands for blocking, the air pipe 10 is made of transparent plastic), the third control valve 15 and the fourth control valve 14 are closed, the first control valve 11 and the second control valve 13 are opened, the physiological saline in the first transfusion cavity 5 enters the second transfusion cavity 6, and the physiological saline and the immune cell inhibitor are mixed uniformly, the first control valve 11 and the second control valve 13 are closed again, the third control valve 15 is opened, mixed liquid enters a human body through the second hose 17, after mixture input is completed, the third control valve 15 and the fourth control valve 14 are closed, the first control valve 11 and the second control valve 13 are opened, normal saline enters the second infusion cavity 6, the infusion bag body 1 is shaken manually, the normal saline in the second infusion cavity 6 is used for cleaning immune cell inhibitor residues, the first control valve 11 and the second control valve 13 are closed, the third control valve 15 is opened, the normal saline in the second infusion cavity 6 enters the human body, pre-flushing, back-flushing and back-flushing can be integrally completed, namely, full-volume back-flushing of immune cell preparations is guaranteed, clinical operation of nurses is facilitated, and pollution risks caused by repeated puncture are well avoided.
While the preferred embodiments of the present invention have been described, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the general inventive concept, and it is intended to cover all such changes and modifications as fall within the true spirit and scope of the invention.
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020145388.5U CN212631331U (en) | 2020-01-23 | 2020-01-23 | A special infusion bag for immune cells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020145388.5U CN212631331U (en) | 2020-01-23 | 2020-01-23 | A special infusion bag for immune cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212631331U true CN212631331U (en) | 2021-03-02 |
Family
ID=74767229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020145388.5U Expired - Fee Related CN212631331U (en) | 2020-01-23 | 2020-01-23 | A special infusion bag for immune cells |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212631331U (en) |
-
2020
- 2020-01-23 CN CN202020145388.5U patent/CN212631331U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210302 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |