CN212417080U - Fermentation liquid extraction tank for production of dehydroepiandrosterone by biotransformation method - Google Patents

Fermentation liquid extraction tank for production of dehydroepiandrosterone by biotransformation method Download PDF

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Publication number
CN212417080U
CN212417080U CN202021097432.6U CN202021097432U CN212417080U CN 212417080 U CN212417080 U CN 212417080U CN 202021097432 U CN202021097432 U CN 202021097432U CN 212417080 U CN212417080 U CN 212417080U
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China
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plate
discharge pipe
weighing
fixedly connected
dehydroepiandrosterone
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CN202021097432.6U
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Chinese (zh)
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李华
刘宇鹏
王刚
杨生玉
孙杨
张昊天
蔡帅
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Henan University
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Henan University
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Abstract

The utility model discloses a fermentation liquid extraction jar is used in production of bioconversion method dehydrogenation epiandrosterone, extraction jar are kept away from one of weighing structure and are served and be connected with the stirring structure, fixedly connected with discharge pipe on one side lateral wall of extraction jar, and the one end of discharge pipe is connected with the sampling tube, and the discharge pipe is connected with seal structure with the junction of sampling tube, is connected with airtight valve on the sampling tube, and the structure internal connection that weighs has the ware of weighing, the utility model discloses the beneficial effect who reaches is: can be to the weight measurement of retort through the ware of weighing of establishhing in the retort bottom, data show through the display, and the staff of just having observed need not extra equipment through the structure of weighing and calculates the measurement alone, can the efficiency of effectual increase production, can discharge pipe and sampling tube connection's leakproofness through seal structure, produce extravagantly when avoiding taking the sample, use screw threaded connection on two extension boards, consolidate the connection of two splint.

Description

Fermentation liquid extraction tank for production of dehydroepiandrosterone by biotransformation method
Technical Field
The utility model relates to an extraction jar, in particular to fermentation liquor extraction jar is used in production of bioconversion method dehydrogenation epiandrosterone belongs to chemical production zymotic fluid extraction correlation structure technical field.
Background
In the production of dehydroepiandrosterone, in order to improve the conversion efficiency, dehydroepiandrosterone and secondary metabolites in the fermentation broth need to be extracted, and the extraction method is mainly used for extracting the fermentation broth, wherein the extraction usually utilizes an organic solvent to extract in an extraction tank, and the fermentation broth needs to be extracted for multiple times so as to ensure sufficient extraction and extract more metabolites.
When extracting now, need measure through extra weighing device or other metering device extraction solvent or zymotic fluid, and the extraction needs the phase of releasing down in reverse, release the upper phase again, add the extraction jar with the zymotic fluid again after collecting relatively the upper phase, add new organic solution and continue the extraction, and above-mentioned operation is repeated many times, very loaded down with trivial details, thereby the process that the measurement work can increase the extraction reduces the efficiency of extraction, and when the sample was examined, still open the top cap of extraction jar and take a sample, can influence the reaction in the extraction jar.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is overcome prior art's defect, a fermentation liquid extraction jar is used in production of bioconversion method dehydroepiandrosterone is provided, through the sampling tube with weigh the structure, can effectual solution foretell when extracting now, need calculate the extraction solvent quantity through extra weighing device or other metering device, thereby this process that can increase the extraction reduces the efficiency of extraction, and examine time measuring in the sample, still need to open the top cap of extraction jar and take a sample, can influence the problem of the reaction mass in the extraction jar.
In order to solve the technical problem, the utility model provides a following technical scheme:
the utility model relates to a zymotic fluid extraction jar is used in production of bioconversion method dehydrogenation epiandrosterone, including the extraction jar, the bottom of extraction jar is connected with the structure of weighing, the extraction jar is kept away from one of the structure of weighing and is served and be connected with the stirring structure, fixedly connected with discharge pipe on one side lateral wall of extraction jar, the one end of discharge pipe is connected with the sampling tube, the discharge pipe is connected with seal structure with the junction of sampling tube, be connected with airtight valve on the sampling tube, the structure internal connection of weighing has the ware.
As an optimized technical scheme of the utility model, the extraction jar includes the retort, establish the viewing aperture on the positive lateral wall of retort, discharge pipe fixed connection is on one side lateral wall of retort, fixedly connected with second entry and first entry on one side lateral wall that the discharge pipe was kept away from to the retort.
As a preferred technical scheme of the utility model, the stirring structure includes the apron, detachable connections places the board in the middle of the bottom of apron, a plurality of screws have been seted up at the border of apron, the through-hole has been seted up to the centre of apron, apron detachable connections is on the top of extraction jar.
As a preferred technical scheme of the utility model, the inside groove has been seted up in the middle of placing the inside of board, the top outer wall fixedly connected with round fixed plate of placing the board, threaded connection has a plurality of fixed screws on the fixed plate, place the board through fixed plate and fixed screw connection in the middle of the bottom of apron, the magnetic plate has been placed in the inside groove, be connected with the power cord on the magnetic plate, the power cord passes through the through-hole and extends to the external world.
As a preferred technical scheme of the utility model, the structure of weighing includes the bottom plate, fixedly connected with round mounting panel in the middle of the top lateral wall of bottom plate, the mounting groove has been seted up to the centre of mounting panel, the bottom is connected with the ware of weighing in the mounting groove, a plurality of supporting legs of bottom fixedly connected with of bottom plate, the bottom of extraction jar extends into in the mounting groove and places on the top of the ware of weighing.
As a preferred technical scheme of the utility model, seal structure includes splint, splint are established two, two splint are semi-circular structure, two the adjacent one end of splint is rotated and is connected with the pivot, two equal fixedly connected with extension plate, two on the one end that pivot was kept away from to splint and the adjacent outer wall the bed course of equal fixedly connected with rubber preparation on the inner wall of splint.
The utility model discloses the beneficial effect who reaches is: can be to the weight measurement of retort through the weighing device of establishhing in the retort bottom, data show through the display, just the staff observes, need not extra equipment through the structure of weighing and calculate alone and measure, can effectual increase efficiency of production, can discharge pipe and sampling tube connection's leakproofness through seal structure, produce extravagantly when avoiding extracting the sample, use screw threaded connection on two extension boards, consolidate the connection of two splint, the bed course of the rubber preparation of establishhing can increase sealing performance, through installing the magnetic plate at the board apron, the inspection maintenance in the later stage of being convenient for.
Drawings
The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention.
In the drawings:
fig. 1 is a schematic perspective view of the present invention;
FIG. 2 is a schematic plan sectional view of the weighing structure of the present invention;
FIG. 3 is a schematic plan sectional view of the stirring structure of the present invention;
fig. 4 is a schematic perspective view of the sealing structure of the present invention.
In the figure: 1. an extraction tank; 11. a reaction tank; 12. a viewing port; 13. a first inlet; 14. a second inlet; 15. a discharge pipe; 2. a stirring structure; 21. a cover plate; 22. a through hole; 23. a screw hole; 24. placing the plate; 241. an inner tank; 242. a magnetic plate; 243. fixing screws; 244. a fixing plate; 245. a power line; 3. a weighing structure; 31. a base plate; 32. mounting a plate; 33. supporting legs; 34. a placing groove; 35. a weighing device; 4. a sealing structure; 41. a splint; 42. a rotating shaft; 43. a cushion layer; 44. an extension plate; 5. a sampling tube; 6. an airtight valve.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are presented herein only to illustrate and explain the present invention, and not to limit the present invention.
Examples
As shown in fig. 1-4, a fermentation liquid extraction jar is used in production of bioconversion method dehydroepiandrosterone, including extraction jar 1, the bottom of extraction jar 1 is connected with the structure 3 of weighing, need not extra equipment through the structure 3 of weighing and calculate alone and measure, can effectual increase efficiency of production, one of structure 3 of weighing is kept away from to extraction jar 1 serves and is connected with stirring structure 2, fixedly connected with discharge pipe 15 on one side lateral wall of extraction jar 1, the one end of discharge pipe 15 is connected with sampling tube 5, discharge pipe 15 is connected with seal structure 4 with the junction of sampling tube 5, be connected with airtight valve 6 on the sampling tube 5, the 3 internal connection of structure of weighing has weighter 35.
The sealing structure 4 comprises two clamping plates 41, two clamping plates 41 are arranged, each clamping plate 41 is of a semicircular structure, one adjacent end of each clamping plate 41 is rotatably connected with a rotating shaft 42, one end of each clamping plate 41, far away from the rotating shaft 42, of each clamping plate 41 is fixedly connected with an extension plate 44, each inner wall of each clamping plate 41 is fixedly connected with a cushion 43 made of rubber, the arranged cushion 43 made of rubber can increase the sealing performance, the sealing performance of the sealing structure 4 can be improved by connecting a discharge pipe 15 with a sampling pipe 5, waste generated during sample extraction is avoided, the stirring structure 2 comprises a cover plate 21, a placing plate 24 is detachably connected in the middle of the bottom of the cover plate 21, a plurality of screw holes 23 are formed in the edge of the cover plate 21, a through hole 22 is formed in the middle of the cover plate 21, the cover plate 21 is detachably connected to the top end of the extraction tank 1, an inner groove 241, the fixing plate 244 is screwed with a plurality of fixing screws 243, the placing plate 24 is connected with the middle of the bottom of the cover plate 21 through the fixing plate 244 and the fixing screws 243, the magnetic plate 242 is placed in the inner groove 241, the magnetic plate 242 is installed on the cover plate 21 to facilitate later-stage inspection and maintenance, the magnetic plate 242 is connected with a power line 245, the power line 245 extends to the outside through the through hole 22, the extraction tank 1 comprises a reaction tank 11, the observation port 12 is arranged on the front side wall of the reaction tank 11, the discharge pipe 15 is fixedly connected with one side wall of the reaction tank 11, the side wall of the reaction tank 11 far away from the discharge pipe 15 is fixedly connected with a second inlet 14 and a first inlet 13, the weighing structure 3 comprises a bottom plate 31, a circle of mounting plate 32 is fixedly connected with the middle of the top side wall of the bottom plate 31, the placing groove 34 is arranged in the middle of the mounting plate 32, the bottom of the placing groove 34 is connected with a weighing device 35, the, the bottom of the bottom plate 31 is fixedly connected with a plurality of supporting legs 33, and the bottom end of the extraction tank 1 extends into the placing groove 34 and is placed on the top of the weighing device 35.
Specifically, the fermentation liquor is conveyed into the reaction tank 11 through the second inlet 14, then the extraction solvent is conveyed into the reaction tank 11 through the first inlet 13, the proportion of the addition of the extraction solvent is judged according to the amount of the fermentation liquor, when the fermentation liquor enters the reaction tank 11, the weight of the reaction tank 11 is measured through the weighing device 35 arranged at the bottom of the reaction tank 11, the data is displayed through the display, the obtained weight data is the data without the self weight of the reaction tank 11, namely the net weight of the fermentation liquor, so that the observation is convenient for workers, the addition of the extraction solvent is converted according to the specific amount of the fermentation liquor, therefore, the amount of the extraction solvent to be added can be easily known by knowing the data of the fermentation liquor, the calculated extraction solvent can be conveyed into the reaction tank 11 through the first inlet 13, and the need of independent calculation and measurement of additional equipment is avoided, the processing efficiency is improved, an observation port 12 is arranged on the side wall of the reaction tank 11, so that a worker can conveniently observe the reaction condition in real time, a discharge pipe 15 is fixedly connected with the side wall of one side of the reaction tank 11, one end of the discharge pipe 15 is connected with the sampling pipe 5, a sealing structure 4 is connected between the discharge pipe 15 and the sampling pipe 5 through the sealing structure 4, the waste generated in the process of extracting a sample is avoided, an airtight valve 6 is additionally arranged on the sampling pipe 5, whether fermentation liquor leaks out from the sampling pipe 5 or not can be avoided, the sealing structure 4 is connected with the discharge pipe 15 and the sampling pipe 5 through two clamping plates 41 in a clamping way, and is connected with two extension plates 44 through screws and threads, the connection of the two clamping plates 41 is reinforced, the arranged cushion layer 43 made of rubber can improve the sealing performance, and is connected with screws in a hole groove on the top end of the reaction tank 11 through the screw holes 23 on the cover plate 21, make apron 21 firmly connected on retort 11, firmly be connected with through set screw 243 in the middle of the bottom of apron 21 and place board 24, magnetic plate 242 is placed in inside groove 241, and the power cord 245 of controlling magnetic plate 242 extends to the external world through the through-hole 22 in the middle of the apron 21, and the staff of being convenient for controls, through installing magnetic plate 242 on apron 21, the inspection maintenance in the later stage of being convenient for.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. The utility model provides a fermentation liquid extraction jar is used in production of bioconversion method dehydroepiandrosterone, a serial communication port, including extraction jar (1), the bottom of extraction jar (1) is connected with weighing structure (3), one of weighing structure (3) is kept away from in extraction jar (1) serves and is connected with stirring structure (2), fixedly connected with discharge pipe (15) on one side lateral wall of extraction jar (1), the one end of discharge pipe (15) is connected with sampling tube (5), discharge pipe (15) are connected with seal structure (4) with the junction of sampling tube (5), be connected with airtight valve (6) on sampling tube (5), weighing structure (3) internal connection has weigher (35).
2. The fermentation liquid extraction tank for producing dehydroepiandrosterone by a bioconversion method according to claim 1, wherein the extraction tank (1) comprises a reaction tank (11), a viewing port (12) is arranged on a front side wall of the reaction tank (11), the discharge pipe (15) is fixedly connected to a side wall of the reaction tank (11), and a second inlet (14) and a first inlet (13) are fixedly connected to a side wall of the reaction tank (11) far away from the discharge pipe (15).
3. The fermentation liquid extraction tank for producing dehydroepiandrosterone by a bioconversion method according to claim 1, wherein the stirring structure (2) comprises a cover plate (21), a placing plate (24) is detachably connected to the middle of the bottom of the cover plate (21), a plurality of screw holes (23) are formed in the edge of the cover plate (21), a through hole (22) is formed in the middle of the cover plate (21), and the cover plate (21) is detachably connected to the top end of the extraction tank (1).
4. The fermentation liquid extraction tank for production of dehydroepiandrosterone by bioconversion method according to claim 3, wherein an inner groove (241) is opened in the middle of the inside of the placing plate (24), a circle of fixing plate (244) is fixedly connected to the outer wall of the top of the placing plate (24), a plurality of fixing screws (243) are screwed on the fixing plate (244), the placing plate (24) is connected to the middle of the bottom of the cover plate (21) through the fixing plate (244) and the fixing screws (243), a magnetic plate (242) is placed in the inner groove (241), a power line (245) is connected to the magnetic plate (242), and the power line (245) extends to the outside through the through hole (22).
5. The fermentation liquid extraction tank for production of dehydroepiandrosterone by a bioconversion method according to claim 1, wherein the weighing structure (3) comprises a bottom plate (31), a circle of mounting plate (32) is fixedly connected to the middle of the side wall of the top of the bottom plate (31), a mounting groove (34) is formed in the middle of the mounting plate (32), a weighing device (35) is connected to the bottom of the mounting groove (34), a plurality of support legs (33) are fixedly connected to the bottom of the bottom plate (31), and the bottom of the extraction tank (1) extends into the mounting groove (34) and is placed on the top of the weighing device (35).
6. The fermentation liquid extraction tank for production of dehydroepiandrosterone by a bioconversion method according to claim 1, wherein the sealing structure (4) comprises two clamping plates (41), two clamping plates (41) are set up, two clamping plates (41) are both semicircular structures, two adjacent ends of the clamping plates (41) are rotatably connected with a rotating shaft (42), two clamping plates (41) are far away from one end of the rotating shaft (42) and are fixedly connected with an extension plate (44) on the adjacent outer wall, and two cushion layers (43) made of rubber are fixedly connected with the inner wall of the clamping plates (41).
CN202021097432.6U 2020-06-15 2020-06-15 Fermentation liquid extraction tank for production of dehydroepiandrosterone by biotransformation method Active CN212417080U (en)

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Application Number Priority Date Filing Date Title
CN202021097432.6U CN212417080U (en) 2020-06-15 2020-06-15 Fermentation liquid extraction tank for production of dehydroepiandrosterone by biotransformation method

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Application Number Priority Date Filing Date Title
CN202021097432.6U CN212417080U (en) 2020-06-15 2020-06-15 Fermentation liquid extraction tank for production of dehydroepiandrosterone by biotransformation method

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114910451A (en) * 2022-05-17 2022-08-16 江苏农牧科技职业学院 CDD light transmission method-based on-line detection device for concentration of mixed medicine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114910451A (en) * 2022-05-17 2022-08-16 江苏农牧科技职业学院 CDD light transmission method-based on-line detection device for concentration of mixed medicine

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