CN210847559U - Reagent tube cleaning device for nucleic acid extraction instrument - Google Patents

Abstract

The utility model relates to a reagent tube cleaning device for a nucleic acid extraction instrument, which comprises a box body, the upper side of the box body is connected to a water pump through a water inlet pipe, the output end of the water pump is connected to a water conduit, and the water conduit runs through the top of the box body The inner wall extends to the inside of the box body, one side of the water conduit is located above the box body with a micro cylinder, the output end of the micro cylinder is connected to a piston rod, the piston rod penetrates through the inner wall above the box body, the The bottom end of the piston rod is connected to a pressure plate, the pressure plate is embedded and connected to the interior of the cleaning agent box, a cleaning agent outlet is arranged under the cleaning agent box, a first motor is arranged on one side of the cylinder, and a transmission shaft passes through the lower part of the first motor A plurality of transmission gears are connected, the transmission gears are arranged inside the movable plate, the transmission gears are connected to the cleaning brush through the rotating shaft, and the cleaning brush is fixedly connected to the outside of the rotating shaft. The utility model uses the motor to drive the cleaning brush to clean the reagent tube , instead of manual cleaning, the cleaning efficiency is high.

Description

Reagent tube cleaning device for nucleic acid extraction instrument

technical field

The utility model relates to a reagent tube cleaning device for a nucleic acid extraction instrument, which belongs to the technical field of reagent tube cleaning.

Background technique

Nucleic acid extractor is a high-tech product for nucleic acid extraction. It has the advantages of high degree of automation, fast extraction, stable results and easy operation. Nucleic acid extractors are divided into two categories: one is large-scale automation, generally called automatic liquid workstation ;The other type is a small automatic nucleic acid extractor, which uses packaged supporting reagents to automatically complete the extraction and purification process. Small automatic instruments are more and more used because of low equipment and operating costs, and easy operation, and can be widely used in Conventional scientific research, genomics, disease control systems, food safety, forensics and other fields, the existing nucleic acid extraction instrument is equipped with a special extraction tray, which can accommodate dozens of extraction reagent tubes at the same time, making the extraction efficiency very high, but the nucleic acid extraction is completed. Afterwards, the cleaning of the reagent tubes is inconvenient, and it is often done manually, which causes great trouble to the medical staff.

Utility model content

The technical problem to be solved by the utility model overcomes the existing defects, and provides a reagent tube cleaning device for a nucleic acid extraction instrument. The reagent tube is cleaned by using a motor-driven cleaning brush instead of manual cleaning, and the cleaning effect is good and the cleaning efficiency is high. The problems in the background technology are effectively solved.

In order to solve the above-mentioned technical problems, the utility model provides the following technical solutions:

A reagent tube cleaning device for a nucleic acid extraction instrument, comprising a box body, the upper side of the box body is connected to a water pump through a water inlet pipe, the output end of the water pump is connected to a water conduit, the water conduit runs through the upper inner wall of the box body and extends to Inside the box body, one side of the water conduit is located above the box body with a micro cylinder, the output end of the micro cylinder is connected to a piston rod, the piston rod penetrates the inner wall above the box body, and the bottom end of the piston rod Connecting a pressure plate, the pressure plate is embedded and connected to the interior of the cleaning agent box, a cleaning agent outlet is arranged under the cleaning agent box, a first motor is arranged on one side of the cylinder, and a number of transmission gears are connected below the first motor through a transmission shaft , the transmission gear is arranged inside the movable plate, the transmission gear is connected to the cleaning brush through the rotating shaft, the cleaning brush is fixedly connected to the outside of the rotating shaft, and the first motor side is located above the box body with a second A motor, a screw rod 1 is connected below the second motor, the screw rod 1 runs through the inner wall of the box, a third motor is arranged on one side of the box body, and the output end of the third motor is connected to the screw rod 2, A sliding seat is sleeved on the second outer part of the screw rod, and a fixing plate is arranged on both sides above the sliding seat. For reagent tubes, the bottom of the third motor is fixed above the grid plate, a water collecting tank is arranged below the grid plate, and a water outlet is provided on one side of the water collecting tank.

As a preferred technical solution of the present invention, a controller is provided on the outer side of the box body, and the water pump, the micro cylinder, the first motor, the second motor, and the third motor input The terminal is electrically connected with the output terminal of the controller through a wire.

As a preferred technical solution of the present invention, there are two each of the transmission gear and the reagent tube, the number of water outlets of the water conduit is two, and the distance between the water outlets and the distance between the reagent tubes Similarly, the number of the cleaning agent outlet is the same as that of the cleaning brush, and the cleaning brush is a soft brush.

As a preferred technical solution of the present invention, one end of the movable plate is embedded in the inner wall of one side of the box body, the first screw rod penetrates through the inner wall of the movable plate, and the inner wall of the movable plate is provided with a connection with the wire The rod is a threaded groove matched with a thread, and the movable plate is connected with the screw rod through a thread.

As a preferred technical solution of the present invention, the sliding seat is internally provided with a thread groove matching the second screw thread, and the movable seat and the second screw rod are connected by thread.

As a preferred technical solution of the present invention, the pressing plate is slidably connected inside the detergent box through the piston rod, the fixing plate is provided with a thread groove matching the screw, and the fixing plate is It is connected with the screw rod through threads, and the snap ring is an arc snap ring.

Technical effects and advantages of the present utility model:

1. The utility model can effectively fix the reagent tube during cleaning by setting a snap ring and a fixing plate, and rotating and fixing the screw, so as to prevent the reagent tube from moving or falling off during cleaning.

2. The utility model can clean a plurality of reagent tubes at the same time by setting a plurality of cleaning brushes, and the cleaning efficiency is high. The cleaning brushes use soft brushes to reduce the damage to the reagent tubes during cleaning.

3. The utility model controls the operation of the equipment by setting the controller, the medical staff only needs to install, and the cleaning process is completed by the machine, which reduces the work intensity of the medical staff and improves the cleaning efficiency.

Description of drawings

The accompanying drawings are used to provide a further understanding of the present invention, and constitute a part of the specification, and are used to explain the present invention together with the embodiments of the present invention, and do not constitute a limitation to the present invention.

Figure 1 is a front view of the present invention.

Figure 2 is a top view of the connection of the transmission gear of the present invention.

FIG. 3 is a top view of the connection of the sliding seat of the present invention.

Labels in the figure: 1, box body; 2, water inlet pipe; 3, water pump; 4, water conduit; 5, micro cylinder; 6, piston rod; 7, pressure plate; 8, detergent box; 9, detergent outlet; 10 , the first motor; 11, the transmission gear; 12, the movable plate; 13, the shaft; 14, the cleaning brush; 15, the second motor; 16, the screw one; 17, the third motor; 18, the screw two; 19, 20, fixed plate; 21, screw; 22, snap ring; 23, reagent tube; 24, grid plate; 25, water collecting tank; 26, water outlet; 27, controller.

Detailed ways

The preferred embodiments of the present utility model will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present utility model, but not to limit the present utility model.

As shown in Figures 1 to 3, a reagent tube cleaning device for a nucleic acid extractor includes a box body 1. The upper side of the box body 1 is connected to a water pump 3 through a water inlet pipe 2, and the output end of the water pump 3 is connected to a water conduit 4. The water conduit 4 runs through the upper inner wall of the box body 1 and extends to the inside of the box body 1. One side of the water conduit 4 is located above the box body 1 with a micro cylinder 5. The output end of the micro cylinder 5 is connected to a piston rod 6, and the piston rod 6 runs through the box body 1. On the upper inner wall, the bottom end of the piston rod 6 is connected to the pressure plate 7, and the pressure plate 7 is embedded and connected to the interior of the cleaning agent box 8. The cleaning agent box 8 is provided with a cleaning agent outlet 9 below. One side of the cylinder 5 is provided with a first motor 10, and the first motor 10 A plurality of transmission gears 11 are connected below through the transmission shaft. The transmission gears 11 are arranged inside the movable plate 12. The transmission gears 11 are connected to the cleaning brush 14 through the rotating shaft 13. The cleaning brush 14 is fixedly connected to the outside of the rotating shaft 13. A second motor 15 is arranged above the 1, and a screw rod 1 16 is connected below the second motor 15. The screw rod 1 16 runs through the inner wall of the box body 1. A third motor 17 is arranged on one side of the box body 1, and the output end of the third motor 17 is connected The second screw 18 is provided with a sliding seat 19 on the outside of the second screw 18, and a fixing plate 20 is arranged on both sides above the sliding seat 19. One side is fixedly connected to the reagent tube 23, the bottom of the third motor 17 is fixed above the grid plate 24, a water collecting tank 25 is arranged under the grid plate 24, and a water outlet 26 is provided on one side of the water collecting tank 25. , The first motor, the second motor, the third motor, and the controller are all in the prior art, so other prior art related to the prior art will not be repeated here.

As shown in FIG. 1, a controller 27 is provided on the outer side of the box body 1, and the input end of the water pump 3, the micro cylinder 5, the first motor 10, the second motor 15, the third motor 17 and the output end of the controller 27 are electrically connected by wires. The controller 27 can control the water pump 3 , the micro cylinder 5 , the first motor 10 , the second motor 15 , and the third motor 17 to operate, instead of cleaning the reagent tube 23 manually.

As shown in Figures 2 and 3, there are two transmission gears 11 and two reagent tubes 23 each, the number of water outlets of the water conduit 4 is two, and the distance between the water outlets is the same as the distance between the reagent tubes 23, and the cleaning agent outlet is the same as the one between the reagent tubes 23. The number of cleaning brushes 14 is the same, the cleaning brush 14 is a soft brush, and the cleaning brush 14 can reduce the damage to the reagent tube 23 during cleaning.

As shown in Figures 1 and 2, one end of the movable plate 12 is embedded in the inner wall of one side of the box body 1, the screw rod 1 16 runs through the inner wall of the movable plate 12, and the movable plate 12 is provided with a thread groove matching the thread of the screw rod 1 16. , the movable plate 12 is connected with the screw one 16 by threads, the sliding seat 19 is provided with a threaded groove matching the thread of the second screw 18, the sliding seat 19 is connected with the second screw 18 by threads, and the movable plate 12 is connected by the screw one 16 moves, thereby extending into the reagent tube 23 for cleaning, and the sliding seat 19 moves the reagent tube 23 through the second screw 18 .

As shown in FIG. 1, the pressure plate 7 is slidably connected inside the detergent box through the piston rod 6, the fixed plate 20 is provided with a threaded groove matching the screw rod 21, the fixed plate 20 is connected with the screw rod 21 by screw thread, and the snap ring 22 is an arc The retaining ring 22 fixes the reagent tube 23 to prevent the reagent tube 23 from moving or falling off during cleaning.

In order to facilitate the understanding of the above technical solutions of the present invention, the working principle or operation mode of the present invention in the actual process will be described in detail below.

In actual use: the program is input in the controller 27 in advance, the medical staff manually puts the reagent tube 23 on the sliding seat 19, rotates the screw 21, and the screw moves to the side of the reagent tube 23, thereby driving the snap ring 22 to move, so that the snap ring 22 is moved. The ring 22 clamps and fixes the reagent tube 23; then the power is turned on, the third motor 17 drives the second screw 18 to rotate, thereby moving the sliding seat 19, when the sliding seat 19 moves to the bottom of the water conduit 4, the third motor 17 stops Running, the water pump 3 is started, and the water is sprayed from the water conduit 4 to flush the reagent tube 23. After the flushing is completed, the third motor 17 runs to move the reagent tube 23 to the bottom of the detergent outlet 9, and the micro cylinder 5 drives the pressure plate 7 to press down , squeeze the cleaning agent in the cleaning agent box 8 into the reagent tube 23, the third motor 17 continues to move to move the reagent tube 23 to the bottom of the cleaning brush 14, the first motor 10 is started, and drives the transmission gear 11 to rotate, thereby driving the rotating shaft 13 The cleaning brush 14 is driven to rotate, the second motor 15 drives the screw rod 16 to rotate, thereby driving the movable plate 12 to move downward, and the cleaning brush 14 is extended into the reagent tube 23 for cleaning. After the cleaning is completed, the third motor 17 is reversed. Move the sliding seat 19 below the water conduit 4, align the outlet of the water conduit 4 with the mouth of the reagent tube, rinse the reagent tube 23 again, and complete the cleaning work.

The above are the preferred embodiments of the present invention. Those skilled in the art can also make changes and modifications to the above-mentioned embodiments. Therefore, the present invention is not limited to the above-mentioned specific embodiments. Any obvious improvement, replacement or modification made on the basis of the present invention belongs to the protection scope of the present invention.

Claims (6)

1. A reagent tube cleaning device for a nucleic acid extraction instrument, comprising a box body (1), characterized in that: the upper side of the box body (1) is connected to a water pump (3) through a water inlet pipe (2), and the water pump ( 3) The output end is connected to a water conduit (4), the water conduit (4) runs through the upper inner wall of the box body (1) and extends to the inside of the box body (1), and one side of the water conduit (4) is located in the box A miniature cylinder (5) is arranged above the body (1), the output end of the miniature cylinder (5) is connected to a piston rod (6), and the piston rod (6) penetrates through the upper inner wall of the box body (1). The bottom end of the piston rod (6) is connected to the pressure plate (7), the pressure plate (7) is embedded and connected to the interior of the cleaning agent box (8), and a cleaning agent outlet (9) is arranged under the cleaning agent box (8). A first motor (10) is provided on one side of the cylinder (5), a plurality of transmission gears (11) are connected below the first motor (10) through a transmission shaft, and the transmission gears (11) are arranged inside the movable plate (12) , the transmission gear (11) is connected to the cleaning brush (14) through the rotating shaft (13), the cleaning brush (14) is fixedly connected to the outside of the rotating shaft (13), and one side of the first motor (10) is located at the A second motor (15) is arranged above the box body (1), a screw rod (16) is connected below the second motor (15), and the screw rod one (16) runs through the box body (1) In the inner wall, a third motor (17) is provided on one side of the box body (1), the output end of the third motor (17) is connected to the second screw (18), and the second screw (18) is sleeved with A sliding seat (19), a fixing plate (20) is provided on both sides above the sliding seat (19), a connecting screw (21) is penetrated inside the fixing plate (20), and one end of the screw (21) is provided with a snap ring (22), one side of the snap ring (22) is fixedly connected to the reagent tube (23), the lower part of the third motor (17) is fixed above the grid plate (24), and a lower part of the grid plate (24) is provided. There is a water collecting tank (25), and a water outlet (26) is provided on one side of the water collecting tank (25). 2. A reagent tube cleaning device for a nucleic acid extraction instrument according to claim 1, characterized in that: a controller (27) is provided on the outer side of the box body (1), the water pump (3), the The input end of the micro cylinder (5), the first motor (10), the second motor (15), and the third motor (17) are electrically connected with the output end of the controller (27) through wires . 3. A reagent tube cleaning device for a nucleic acid extraction instrument according to claim 1, characterized in that: there are two each of the transmission gear (11) and the reagent tube (23), and the water conduit (4) ) The number of water outlets is two, and the distance between the water outlets is the same as the distance between the reagent tubes (23), the number of the cleaning agent outlets and the cleaning brush (14) are the same, and the cleaning brush (14) It is a soft brush. The reagent tube cleaning device for a nucleic acid extraction instrument according to claim 1, characterized in that: one end of the movable plate (12) is embedded in the inner wall of one side of the box (1), and one end of the screw rod is embedded in the inner wall of the box (1). (16) runs through the inner wall of the movable plate (12), the movable plate (12) is internally provided with a thread groove that matches the thread of the lead screw one (16), and the movable plate (12) is connected to the The screw one (16) is connected by a thread. 5. A reagent tube cleaning device for a nucleic acid extractor according to claim 1, characterized in that: the sliding seat (19) is provided with a thread groove matching the thread of the second screw (18), The sliding seat (19) is connected with the second screw rod (18) through threads. 6 . The reagent tube cleaning device for a nucleic acid extractor according to claim 1 , wherein the pressure plate ( 7 ) is slidably connected inside the detergent box through the piston rod ( 6 ), and the The fixing plate (20) is internally provided with a threaded groove matching the screw (21), the fixing plate (20) is connected with the screw (21) through a screw thread, and the snap ring (22) is an arc-shaped snap ring ring.

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