CN210811742U - A intragastric needle for adult mouse - Google Patents
A intragastric needle for adult mouse Download PDFInfo
- Publication number
- CN210811742U CN210811742U CN201921116450.1U CN201921116450U CN210811742U CN 210811742 U CN210811742 U CN 210811742U CN 201921116450 U CN201921116450 U CN 201921116450U CN 210811742 U CN210811742 U CN 210811742U
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- needle
- connector
- utility
- model
- adult
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Abstract
The utility model provides a pair of a stomach filling needle for adult mouse, including connector, needle tubing and syringe needle, the round platform body that the connector was invertd for cavity, the one end of connector and the takeover phase-match of pipetting gun, the other end communicates with the one end of needle tubing, and the needle tubing is a hollow cylinder and syringe needle intercommunication, and the syringe needle is the ellipsoid, the utility model discloses at mouse gavage in-process, make in the medicine can accurately arrive experimental mice alimentary canal quantificationally, solve this difficult problem that traditional gavage method is inaccurate, can guarantee in medicine ration, homogeneous and the alimentary canal of injecting adult mouse with no leaking when gavage to guarantee injection safe and reliable at every turn, reach the most ideal experimental result, also adopt the design of the experimental operation of being convenient for most simultaneously, make this utility model can serve for the experiment better.
Description
Technical Field
The utility model relates to the technical field of medical machinery, concretely relates to an intragastric administration needle for adult mice.
Background
With the development of modern life science and technology, animal experiments become an indispensable experimental method. For example, in the research of the treatment medicine for the deafness, a medicine test is often required to be carried out on the mice by adopting a gastric lavage mode. Mouse gavage of the prior art is generally connected to a 1mL syringe by a 14-gauge gavage needle, but has the following disadvantages:
1. traditional gastric lavage needles are not accurate enough. The minimum scale of a 1mL injector matched with the traditional gastric perfusion needle is 0.02mL, namely 20 muL, and under the influence of operation and human eye visual angle, the perfusion dose is difficult to reach very accurate, and the accuracy and reliability of an experimental result are possibly influenced.
2. The traditional gastric perfusion needle is made of metal materials, has high hardness, is not easy to bend, has low compatibility with organism tissues, is careless to operate, and is easy to cause the digestive tract injury, even hemorrhage or death of mice.
3. The traditional stomach filling needle is made of an antirust metal material, so that the die forging difficulty is high, and the manufacturing process is relatively complex and expensive.
Disclosure of Invention
In order to overcome the technical defects, the utility model aims to provide an intragastric perfusion needle for adult mice, which has accurate experimental precision, high biocompatibility and low cost.
In order to achieve the above object, the utility model discloses a concrete solution provides a gavage needle for adult mouse, a serial communication port, including connector, needle tubing and syringe needle, the round platform body that the connector was invertd for cavity, the one end of connector and the takeover phase-match of pipetting gun, the other end of connector with the one end intercommunication of needle tubing, the needle tubing is a hollow circular cylinder, the other end and the syringe needle intercommunication of needle tubing, the syringe needle is the ellipsoid.
Preferably, the material of the connector, the needle tube and the needle head of the gastric perfusion needle of the utility model is acrylic resin.
Preferably, the outer diameter of the upper bottom surface of the connector of the gastric perfusion needle is 7.5mm, the inner diameter is 5.5mm, the outer diameter of the lower bottom surface is 7.5mm, and the inner diameter is 5.5 mm.
Further, the utility model discloses the connector butt joint of gavage needle 20 ~ 200 mu L liquid-transfering gun.
Preferably, the length of the connector of the gastric perfusion needle of the utility model is 5 cm.
Preferably, the outer diameter of the needle tube of the gastric perfusion needle of the utility model is 1.4mm, the inner diameter is 1.1mm, and the length is 30 mm.
Preferably, the length of the needle head of the gastric perfusion needle of the utility model is 3mm, and the length of the short shaft of the needle head is 2.12 mm.
Preferably, the utility model discloses the stomach filling needle prints the preparation through 3D and forms.
The utility model provides a pair of a stomach filling needle for adult mouse, including connector, needle tubing and syringe needle, the round platform body that the connector was invertd for cavity, the one end of connector and the takeover phase-match of pipetting gun, the other end communicates with the one end of needle tubing, and the needle tubing is a hollow cylinder and syringe needle intercommunication, and the syringe needle is the ellipsoid, the utility model discloses at mouse gavage in-process, make in the medicine can accurately arrive experimental mice alimentary canal quantificationally, solve this difficult problem that traditional gavage method is inaccurate, can guarantee in medicine ration, homogeneous and the alimentary canal of injecting adult mouse with no leaking when gavage to guarantee injection safe and reliable at every turn, reach the most ideal experimental result, also adopt the design of the experimental operation of being convenient for most simultaneously, make this utility model can serve for the experiment better.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.
Fig. 1 is a structural diagram of an intragastric perfusion needle according to an embodiment of the present invention.
Description of the main element symbols:
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
An intragastric needle for adult mice according to an embodiment of the present invention will be described with reference to the accompanying drawings.
Fig. 1 is a schematic structural view of an intragastric perfusion needle for an adult mouse according to an embodiment of the present invention.
As shown in fig. 1, the stomach filling needle for adult mice comprises a connector 1, a needle tube 2 and a needle head 3.
As an embodiment of the present invention, the connector 1 is a hollow inverted round table. One end of the connector 1 is matched with the connecting pipe of the liquid-transferring gun, and the other end of the connector is communicated with one end of the needle tube 2.
Furthermore, the outer diameter of the upper bottom surface of the connector 1 is 7.5mm, and the inner diameter is 5.5 mm. The gastric perfusion needle can be connected with a 20-200 mu L liquid-transferring gun. The injection of the medicine with accurate quantification is realized through the operation of the liquid-transferring gun.
As an embodiment of the utility model, the needle tube 2 is a hollow cylinder, similar to a 14-gauge stomach filling needle. The other end of the needle tube is communicated with the needle head 3. The outer diameter of the needle tube is 1.4mm, the inner diameter is 1.1mm, and the length is 30 mm.
As an embodiment of the present invention, the needle 3 is an ellipsoid. The length of the needle 3 is 3mm, and the length of the short axis of the needle 3 is 2.12 mm. The needle 3 is an ellipsoid, so that the discomfort of the mouse is reduced to the maximum extent, and the test is facilitated.
The utility model discloses an intragastric needle for adult mouse adopts 3D to print, and the material of connector 1, needle tubing 2 and syringe needle 3 is acrylic resin. Simple structure, low cost and reliable quality.
As an embodiment of the utility model, this gavage needle can connect the medicine of the required dose of 20 ~ 200 uL pipetting gun extraction, and the syringe needle inserts the alimentary canal of adult mouse, slowly injects the medicine, and in the medicine can get into the mouse alimentary canal along gavage needle uniformly, does not have to spill, do not have jam, no air and other impurity entering, and gavage needle adopts acrylic resin to make, and is littleer to the damage of mouse, and the at utmost has reduced the discomfort of mouse.
In the actual use process, the intragastric administration needle is matched with a liquid-transferring gun to inject the medicine into the alimentary canal of the adult mouse. Adult male C57 mice (10-30 g in weight) were injected with 200. mu.L PBS per mouse, and the injection rate was 100% without death and digestive tract injury.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention, and any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.
Claims (8)
1. The utility model provides an enema needle for adult mouse, a serial communication port, includes connector, needle tubing and syringe needle, the round platform body that the connector was invertd for cavity, the one end of connector and the takeover phase-match of pipetting gun, the other end of connector with the one end intercommunication of needle tubing, the needle tubing is a hollow circular cylinder, the other end and the syringe needle intercommunication of needle tubing, the syringe needle is the ellipsoid.
2. The gastric lavage needle for adult mice according to claim 1, wherein the material of the connector, the needle tube and the needle head is acrylic resin.
3. The gastric lavage needle for adult mice according to claim 1 wherein the connector has an upper bottom surface with an outer diameter of 7.5mm and an inner diameter of 5.5mm, and a lower bottom surface with an outer diameter of 7.5mm and an inner diameter of 5.5 mm.
4. The gastric perfusion needle for adult mice as claimed in claim 2, wherein the connector is butted with a 20-200 μ L pipette gun.
5. The gastric lavage needle for an adult mouse according to claim 1 wherein the connector is 5cm in length.
6. The gastric lavage needle for an adult mouse according to claim 1 wherein the needle tube has an outer diameter of 1.4mm, an inner diameter of 1.1mm and a length of 30 mm.
7. The gastric lavage needle for adult mice according to claim 1 wherein the length of the needle head is 3mm and the length of the minor axis of the needle head is 2.12 mm.
8. The gastric lavage needle for adult mice according to any one of claims 1 to 7, wherein the gastric lavage needle is fabricated by 3D printing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921116450.1U CN210811742U (en) | 2019-07-16 | 2019-07-16 | A intragastric needle for adult mouse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921116450.1U CN210811742U (en) | 2019-07-16 | 2019-07-16 | A intragastric needle for adult mouse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210811742U true CN210811742U (en) | 2020-06-23 |
Family
ID=71268214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921116450.1U Expired - Fee Related CN210811742U (en) | 2019-07-16 | 2019-07-16 | A intragastric needle for adult mouse |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210811742U (en) |
-
2019
- 2019-07-16 CN CN201921116450.1U patent/CN210811742U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200623 |