CN209542458U - Integral type for chemical illumination immunity analysis instrument incubates light measurer - Google Patents
Integral type for chemical illumination immunity analysis instrument incubates light measurer Download PDFInfo
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- CN209542458U CN209542458U CN201920239956.5U CN201920239956U CN209542458U CN 209542458 U CN209542458 U CN 209542458U CN 201920239956 U CN201920239956 U CN 201920239956U CN 209542458 U CN209542458 U CN 209542458U
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- protective shell
- analysis instrument
- incubation
- immunity analysis
- substrate
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- 238000004458 analytical method Methods 0.000 title claims abstract description 20
- 238000005286 illumination Methods 0.000 title claims abstract description 19
- 230000036039 immunity Effects 0.000 title claims abstract description 19
- 239000000126 substance Substances 0.000 title claims abstract description 19
- 238000011534 incubation Methods 0.000 claims abstract description 30
- 230000001681 protective effect Effects 0.000 claims abstract description 29
- 239000000758 substrate Substances 0.000 claims abstract description 16
- 230000003287 optical effect Effects 0.000 claims abstract description 13
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 30
- 229910052742 iron Inorganic materials 0.000 claims description 15
- 230000005540 biological transmission Effects 0.000 claims description 7
- 238000005192 partition Methods 0.000 claims description 5
- 238000005485 electric heating Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 3
- 238000009413 insulation Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 5
- 238000009434 installation Methods 0.000 abstract description 5
- 230000001360 synchronised effect Effects 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 4
- 239000000376 reactant Substances 0.000 description 4
- 230000000903 blocking effect Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000011324 bead Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000003556 assay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002038 chemiluminescence detection Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 238000000163 radioactive labelling Methods 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model discloses a kind of integral types for chemical illumination immunity analysis instrument to incubate light measurer; including incubating unit; incubating unit includes substrate; rotation is provided with the incubation disk for offering and incubating slot in protective shell on substrate; survey light unit is provided on protective shell; surveying light unit includes mounting disc, and mounting disc outer surface is provided with photomultiplier tube, and offers loophole on the protection shell side wall and cover board of photomultiplier tube corresponding position；Rotation is provided with the rotating disc with optical filter in the groove of mounting disc inner surface.The utility model advantage is that will survey light unit is integrated on the protective shell for incubating unit, saves installation space, realizes synchronous incubation and surveys light, improves detection efficiency；The movable barn door that top cover reaction cup picks and places on window slides back and forth along the chute, is not only convenient for picking and placing reaction cup, also has interception, improves the reliability and accuracy of pattern detection result, and then guarantee the repeatability of chemical illumination immunity analysis instrument.
Description
Technical field
The utility model relates to chemiluminescence detection technology fields, are used for chemiluminescence immune assay more particularly, to one kind
The integral type of instrument incubates light measurer.
Background technique
Chemical illumination immunity analysis instrument is built upon in the theoretical basis of radiating immuning analysis technology, to mark luminous agent to be
A kind of non-radioactive labelling immunoassay method that tracer signal is set up, because it has specific height, high sensitivity, separation letter
Just, the advantages that nontoxic, safety and stability, it is widely applied in scientific research, hospital and testing agency.Chemical illumination immunity analysis instrument
Including sample transmission unit, magnetic bead cleaning unit, handgrip unit, sample-adding unit, unit and survey light unit are incubated, incubates unit pair
Reactant in reaction cup, which heats, to be incubated, and is to guarantee the complete final steps of reactant reaction.Existing incubation unit and survey light
Unit is individually arranged, and needs installation space big, causes chemical illumination immunity analysis instrument volume big and heavy, occupied space；
Reaction cup carrier top cover is equipped with cover board, and the window for picking and placing reaction cup, the setting of window opening are offered on cover board, and light is easy
Reactant into reaction tray irradiation reaction cup, influences measurement effect.
Summary of the invention
The utility model aim is to provide a kind of integral type for chemical illumination immunity analysis instrument and incubates light measurer,
Space is not only saved, volume is reduced, moreover it is possible to which complete extraneous light, which is radiated at, to be avoided in reaction cup, guarantees the reliability of testing result
And repeatability.
To achieve the above object, the utility model takes following technical proposals:
Integral type described in the utility model for chemical illumination immunity analysis instrument incubates light measurer, including incubates single
Member, the incubation unit includes substrate, and the upper surface of base plate is provided with the protective shell of structure in a ring, in the protective shell
Rotation is provided with by the incubation disk of power mechanism driving rotation, described to incubate the incubation offered on disk for placing response cup
Slot；Electric heating sheets are provided between the incubation disk and the protective shell bottom wall；It is provided on the side wall of the protective shell
Light unit is surveyed, the light unit of surveying includes the mounting disc being connected on protection shell side wall by cover board, the mounting disc outer surface
Horizontally disposed to have photomultiplier tube, photomultiplier tube inner end extends in mounting disc, the protective shell with photomultiplier tube corresponding position
Loophole is offered on side wall and the cover board；Rotation is provided with rotating disc, the rotation in the groove of mounting disc inner surface
The optical filter for filtering the photomultiplier tube optical signal is installed on disk.
The top cover lower surface of the protective shell is arranged at intervals with multiple annular partitions, and adjacent two annular partition forms anti-
The only limition orientation slot that reaction cup is shaken；It is recessed the sliding slot radially extended in the middle part of the top cover upper surface, is provided with institute
It states sliding on the reaction cup pick-and-place window on sliding slot bottom wall and is provided with movable barn door, the activity at cap edge hides
Tabula rasa end is provided with the iron plate upwardly extended.
The power mechanism includes being connected in the first motor of the base lower surface and passing through transmission group by first motor
The rotary shaft of part driving, the incubation disk are connected at the top of the rotary shaft.
The protective shell and the substrate are provided with heat-insulated between the upper and lower every setting between the protective shell and the substrate
Block.
The rotary shaft bottom end is set with code-disc in the form of annular discs, and the base lower surface is used by the setting of connecting plate interval
Detect the origin sensor and sensor for countering of the code-disc position.
The utility model advantage is that will survey light unit is integrated on the protective shell for incubating unit, saves installation space, contracting
The small volume of chemical illumination immunity analysis instrument, keeps chemical illumination immunity analysis instrument structure more compact, convenient for transfer, also realizes
Synchronous incubation and survey light, improve detection efficiency；The movable barn door that top cover reaction cup picks and places on window slides back and forth along the chute,
It is not only convenient for picking and placing reaction cup, also there is interception, improve the reliability and accuracy of pattern detection result, and then guarantee
The repeatability of chemical illumination immunity analysis instrument.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
Fig. 2 is the schematic cross-sectional view of Fig. 1.
Fig. 3 is the annexation figure of rotating disk described in the utility model and mounting disc.
Fig. 4 is the structural schematic diagram of top cover described in the utility model.
Fig. 5 is the present invention looks up structural representation of top cover described in the utility model.
Fig. 6 is the backsight shaft side figure (omit and survey light unit) of the utility model.
Fig. 7 is the structural schematic diagram with the matching used handgrip unit of the utility model.
Specific embodiment
As shown in Figure 1, 2, the integral type described in the utility model for chemical illumination immunity analysis instrument, which incubates, surveys light dress
It sets, including incubates unit, the incubation unit includes substrate 1.1, and 1.1 upper surface of substrate is arranged at intervals with structure in a ring
Protective shell 1.2, in the protective shell 1.2 rotation be provided with by power mechanism driving rotation incubation disk 1.3, the incubation
The incubation slot 1.4 of multiple groups arrangement annular in shape is offered on disk 1.3；The power mechanism includes being connected under the substrate 1.1
The first motor 4.1 on surface and (transmission component is toothed belt transmission pair, certainly practical by transmission component by first motor 4.1
It is also possible to that Worm Wheel System is secondary or belt transmission when manufacture) rotary shaft 4.2 of driving, the incubation disk 1.3 is connected in
4.2 top of rotary shaft, first motor 4.1 is driven by rotary shaft 4.2 incubates the rotation of disk 1.3；On 1.2 bottom wall of protective shell
Central aperture edge turns down formation installation side 1.6, the installation side 1.6 and the axle sleeve 4.3 being sleeved in rotary shaft 4.2 vertically upward
It is fixedly connected with, installs and be provided with sealing ring between side 1.6 and axle sleeve 4.3；4.3 inner ring surface of axle sleeve is arranged at intervals with bearing 4.4 up and down,
Guarantee that protective shell 1.2 is motionless in 4.2 rotation process of rotary shaft；It is set between 1.2 bottom wall of the incubation disk 1.3 and the protective shell
Electric heating sheets 1.5 are equipped with, heat insulation 5 is provided between protective shell 1.2 and substrate 1.1；
As shown in Figure 1-3, being provided with survey light unit on the side wall of the protective shell 1.2, the survey light unit includes logical
The mounting disc 2.2 that cover board 2.1 is connected on protection shell side wall is crossed, 2.2 outer surface of mounting disc is horizontally disposed photomultiplier transit
Pipe 2.3,2.3 inner end of photomultiplier tube extend to the groove of 2.2 inner surface of mounting disc, with 2.3 corresponding position of photomultiplier tube
Loophole 2.4 is offered on 1.2 side wall of protective shell and the cover board 2.1；Rotation setting in the groove of 2.2 inner surface of mounting disc
There is the rotating disc 2.5 driven by the second motor 2.7, is installed on the rotating disc 2.5 for filtering the photomultiplier tube 2.3
The optical filter 2.6 of optical signal.Survey light when, photomultiplier tube 2.3 be powered, the second motor 2.7 drive rotating disc 2.5 rotate, when turn
When optical filter 2.6 on Moving plate 2.5 is turned at 2.3 face position of photomultiplier tube, optical signal is filtered, it is filtered
Light harness is radiated in the reaction cup for needing to survey light by loophole 2.4, rotational frequency and reaction cup the rotation frequency of optical filter 2.6
Rate is consistent, realizes the continuous survey light of multiple reaction cups.
As shown in Figure 4,5,3 lower surface of top cover of protective shell 1.2 is arranged at intervals with multiple annular partitions 3.1, adjacent two institute
It states annular partition 3.1 and forms the limition orientation slot 3.2 for preventing reaction cup from shaking, guide groove is corresponding with about 1.4 slot is incubated, and incubates
The reaction cup incubated in slot 1.4 in 1.3 rotation process of disk is rotated along limition orientation slot 3.2；In the middle part of 3 upper surface of top cover
The sliding slot 3.3 that spill extends radially into is provided with the reaction cup on 3.3 bottom wall of sliding slot and picks and places sliding setting on window 3.4
There is movable barn door 3.5,3.5 end of the movable barn door close to 3 edge of top cover is provided with the iron plate upwardly extended
3.6, movable barn door 3.5 picks and places window 3.4 for blocking reaction cup, and ambient irradiation is avoided to incubate the reaction in disk 1.3
Cup, guarantees the accuracy and repeatability of photometry result.
The handgrip unit of the activity opening of barn door 3.5 described in the utility model, closing and chemiluminescent analyzer matches
It closes, specifically as shown in fig. 7, being provided with push rod 7.1, the bottom of push rod 7.1 on the handgrip unit 7 of chemical illumination immunity analysis instrument
It is provided with the magnet 7.2 for adsorpting iron plate 3.6, when needing to take out reaction cup or by reaction cup placing response cup, handgrip
Unit is moved horizontally along guide rail 7.3, when handgrip unit, which is moved to, to be incubated above unit, 7.2 adsorpting iron plate 3.6 of magnet, and handgrip
Unit sails out of reaction cup by 3.6 drive activity barn door 3.5 of iron plate and picks and places the exposing incubation slot 1.4 of window 3.4, and handgrip unit will
Reaction cup is placed in the incubation slot 1.4 below handgrip, or the reaction cup immediately below crawl；Then handgrip unit is along guide rail
7.3 opposite directions move horizontally, and magnet 7.2 is moved by iron sheet drive activity barn door 3.5 to home position in moving process,
Window 3.4 is picked and placed for blocking reaction cup, handgrip unit continues opposite direction movement until sailing out of incubation unit, and magnet 7.2 sails out of
Iron plate 3.6 restores movable barn door 3.5 to original blocking position.
As shown in fig. 6,4.2 bottom end of rotary shaft is fixed with by bolt to be precisely controlled the specific location of reaction cup
The code-disc 6.1 of structure in the form of annular discs, 1.1 lower surface of substrate pass through the interval of the connecting plate 6.2 setting detection code-disc 6.1
The signal output end of the origin sensor 6.3 and sensor for countering 6.4 of position, origin sensor 6.3 and sensor for countering 6.4 with
The signal input part of single-chip microcontroller is electrically connected, and accurately controls the position for incubating disk 1.3 by accurately monitoring 6.1 position of code-disc, after
And precisely monitor the specific turned position of reaction cup.
The course of work of the utility model is summarized as follows:
In incubation period, the energization of electric heating sheets 1.5 carries out incubation heating to the reactant in reaction cup；First motor
4.1 by the drive incubation rotation of disk 1.3 of rotary shaft 4.2, the reaction cup of handgrip unit picks magnetic bead cleaning unit and along its guide rail
7.3 is mobile to unit is incubated, and the adsorpting iron plate 3.6 when magnet 7.2 is moved at 3.6 position of iron plate continues to move to handgrip unit,
7.2 promotion activity shading baffle of magnet sails out of reaction cup and picks and places the exposing incubation slot 1.4 of window 3.4, and handgrip unit unclamps reaction cup
And reaction cup is placed on and is incubated in slot 1.4；Then handgrip unit is moved along 7.3 opposite direction of guide rail, and magnet 7.2 drives iron plate 3.6
The movement of window 3.4 is picked and placed to reaction cup, handgrip unit sails out of iron plate 3.6 when incubating unit and is detached from magnet 7.2, at this time activity shading
Plate 3.5 is just covered to be picked and placed above window 3.4 in reaction cup, avoids entering light.Above-mentioned reaction cup placement operation is repeated, realizes reaction cup
Continuous placement.
After the completion of incubation, photomultiplier tube 2.3 is powered, and the second motor 2.7 drives rotating disc 2.5 to rotate, when rotating disc 2.5
On optical filter 2.6 when turning at 2.3 face position of photomultiplier tube, optical signal is filtered, filtered light line
Beam is radiated in the reaction cup for needing to survey light by loophole 2.4, the velocity of rotation and reaction cup rotational frequency one of optical filter 2.6
It causes, realizes the continuous survey light of multiple reaction cups.
It surveys after the completion of light, handgrip unit is moved to along guide rail 7.3 and incubates above unit, and magnet 7.2 is driven by iron sheet and lived
Dynamic barn door 3.5, which sails out of reaction cup pick-and-place window 3.4, will survey the reaction cup taking-up after light, after then opposite direction movement will survey light
Reaction cup, which is grabbed, to be sent to specified recovery position, and when handgrip unit sails out of incubation unit, magnet 7.2 passes through 3.6 drive activity of iron plate and hides
Tabula rasa 3.5 picks and places the movement of window 3.4 to reaction cup, and when magnet 7.2 sails out of iron plate 3.6, activity barn door 3.5 just will reaction
Cup picks and places window 3.4 and is completely covered by.Aforesaid operations are repeated, realize that has detected sample is continuously withdrawn operation.
Claims (5)
1. a kind of integral type for chemical illumination immunity analysis instrument incubates light measurer, including incubates unit, the incubation is single
Member includes substrate (1.1), and substrate (1.1) upper surface is provided with the protective shell (1.2) of structure in a ring, in the protective shell
(1.2) rotation is provided with the incubation disk (1.3) rotated by power mechanism driving in, offers and is used on the incubation disk (1.3)
The incubation slot (1.4) of placing response cup；It is characterized by: between the incubation disk (1.3) and the protective shell (1.2) bottom wall
It is provided with electric heating sheets (1.5)；Survey light unit is provided on the side wall of the protective shell (1.2), the survey light unit includes
It is connected in the mounting disc (2.2) on protection shell side wall by cover board (2.1), mounting disc (2.2) outer surface is horizontally disposed to be had
Photomultiplier tube (2.3), photomultiplier tube (2.3) inner end extends in mounting disc (2.2), corresponding with photomultiplier tube (2.3)
Loophole (2.4) are offered on protective shell (1.2) side wall and the cover board (2.1) at place；Mounting disc (2.2) inner surface it is recessed
Rotation is provided with rotating disc (2.5) in slot, is installed on the rotating disc (2.5) for filtering the photomultiplier tube (2.3)
The optical filter (2.6) of optical signal.
2. the integral type according to claim 1 for chemical illumination immunity analysis instrument incubates light measurer, feature exists
In: top cover (3) lower surface of the protective shell (1.2) is arranged at intervals with multiple annular partitions (3.1), it is adjacent two it is described annular every
Plate (3.1) forms the limition orientation slot (3.2) for preventing reaction cup from shaking；Diameter is recessed in the middle part of top cover (3) upper surface
To the sliding slot (3.3) of extension, the reaction cup being provided on the sliding slot (3.3) bottom wall is picked and placed to slide on window (3.4) and is provided with
Movable barn door (3.5), described movable barn door (3.5) end close to top cover (3) edge are provided with the iron upwardly extended
Piece (3.6).
3. the integral type according to claim 1 for chemical illumination immunity analysis instrument incubates light measurer, feature exists
In: the power mechanism includes being connected in the first motor (4.1) of the substrate (1.1) lower surface and by first motor (4.1)
The rotary shaft (4.2) driven by transmission component, the incubation disk (1.3) are connected at the top of the rotary shaft (4.2).
4. the integral type according to claim 1 for chemical illumination immunity analysis instrument incubates light measurer, feature exists
In: the protective shell (1.2) and the substrate (1.1) are between the upper and lower every setting, in the protective shell (1.2) and the substrate
(1.1) heat insulation (5) are provided between.
5. the integral type according to claim 3 for chemical illumination immunity analysis instrument incubates light measurer, feature exists
In: rotary shaft (4.2) bottom end is set with code-disc in the form of annular discs (6.1), and substrate (1.1) lower surface passes through connecting plate
(6.2) the interval setting origin sensor (6.3) and sensor for countering (6.4) for detecting code-disc (6.1) position.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920239956.5U CN209542458U (en) | 2019-02-26 | 2019-02-26 | Integral type for chemical illumination immunity analysis instrument incubates light measurer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920239956.5U CN209542458U (en) | 2019-02-26 | 2019-02-26 | Integral type for chemical illumination immunity analysis instrument incubates light measurer |
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| Publication Number | Publication Date |
|---|---|
| CN209542458U true CN209542458U (en) | 2019-10-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920239956.5U Active CN209542458U (en) | 2019-02-26 | 2019-02-26 | Integral type for chemical illumination immunity analysis instrument incubates light measurer |
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| CN (1) | CN209542458U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112114159A (en) * | 2020-10-23 | 2020-12-22 | 安图实验仪器(郑州)有限公司 | Continuous Delivery Device for Cuvette Incubation Photometry |
| CN112162105A (en) * | 2020-10-23 | 2021-01-01 | 安图实验仪器(郑州)有限公司 | High-speed magnetic-washing temperature-raising photometric device |
| CN114295848A (en) * | 2021-12-17 | 2022-04-08 | 重庆国科医工科技发展有限公司 | Chemiluminescence immunoassay appearance |
| CN115327096A (en) * | 2022-07-20 | 2022-11-11 | 世纪一束(杭州)医学诊断科技有限公司 | Detection disc applied to immunoassay analyzer |
| WO2024138936A1 (en) * | 2022-12-28 | 2024-07-04 | 重庆国科医创科技发展有限公司 | Shading detection mechanism and immunoassay analyzer |
-
2019
- 2019-02-26 CN CN201920239956.5U patent/CN209542458U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112114159A (en) * | 2020-10-23 | 2020-12-22 | 安图实验仪器(郑州)有限公司 | Continuous Delivery Device for Cuvette Incubation Photometry |
| CN112162105A (en) * | 2020-10-23 | 2021-01-01 | 安图实验仪器(郑州)有限公司 | High-speed magnetic-washing temperature-raising photometric device |
| CN112162105B (en) * | 2020-10-23 | 2024-07-09 | 安图实验仪器(郑州)有限公司 | High-speed magnetic washing incubation photometry device |
| CN114295848A (en) * | 2021-12-17 | 2022-04-08 | 重庆国科医工科技发展有限公司 | Chemiluminescence immunoassay appearance |
| CN115327096A (en) * | 2022-07-20 | 2022-11-11 | 世纪一束(杭州)医学诊断科技有限公司 | Detection disc applied to immunoassay analyzer |
| CN115327096B (en) * | 2022-07-20 | 2023-12-08 | 世纪一束(杭州)医学诊断科技有限公司 | Detection disc applied to immunity analyzer |
| WO2024138936A1 (en) * | 2022-12-28 | 2024-07-04 | 重庆国科医创科技发展有限公司 | Shading detection mechanism and immunoassay analyzer |
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