CN208583015U - A kind of bio-pharmaceuticals extraction purification device - Google Patents
A kind of bio-pharmaceuticals extraction purification device Download PDFInfo
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- CN208583015U CN208583015U CN201820938248.6U CN201820938248U CN208583015U CN 208583015 U CN208583015 U CN 208583015U CN 201820938248 U CN201820938248 U CN 201820938248U CN 208583015 U CN208583015 U CN 208583015U
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- extractor
- delivery pipe
- bio
- culture tank
- spray dryer
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Abstract
The utility model discloses a kind of bio-pharmaceuticals extraction purification devices, including extractor, culture tank, knockout drum, concentration tank and spray dryer, extractor is connected to culture tank top by outlet tube, culture culture tank is connect by supernatant delivery pipe with knockout drum one end, the first pressurizing delivery pump is provided on supernatant delivery pipe pipeline, the knockout drum other end connects separating liquid outlet pipe, the separating liquid outlet pipe other end is connected to the top of concentration tank side, concentration tank lower part is connected with concentrate delivery pipe, the second pressurizing delivery pump is provided on concentrate delivery pipe pipeline, the concentrate delivery pipe other end is connected on the spray head at the top of spray dryer, the gas gathering mask side on spray dryer top is connected with high temperature air delivery pipe, spray dryer lower part is provided with drug collecting vessel.The utility model is extracted using pressurized, heated, can reduce extraction time and have preferable extraction effect, and separation can increase the purity of drug using pressurization multilayer separation.
Description
Technical field
The utility model belongs to field of pharmaceutical equipment, and in particular to a kind of bio-pharmaceuticals extraction purification device.
Background technique
Nowadays, medicine biological technique is fast-developing, and bio-pharmaceutical raw material is based on natural biomaterial, including micro- life
Object, human body, animal, plant, marine organisms etc., plant it is many kinds of, many plants medical value all with higher is being planted
During the bio-pharmaceuticals of species, traditional technology mainly includes processing, extracting and developing, concentration, drying and the crushing of medicinal material,
And existing processing mode extract when, the time often extracted is longer or purity is too low, influence final product quality, plant
The distinctive color of object extracting solution is also more difficult, causes production cost excessively high.
Utility model content
To overcome technological deficiency of the existing technology, the utility model discloses a kind of bio-pharmaceuticals to be filled with extraction purification
It sets.It is extracted using pressurized, heated, extraction time can be reduced and there is preferable extraction effect, separation is using pressurization multilayer
Separation, can increase the purity of drug, obtain preferable drug quality, reduce cost.
A kind of bio-pharmaceuticals extraction purification device of the utility model, including extractor, culture tank, knockout drum, concentration
Tank and spray dryer, the hinged gland in extractor top, extractor are internally provided with sieve plate, are provided with bulge loop on sieve plate,
Sieve plate top is provided with drug bucket, and drug bucket bottom is provided with the clamping ring matched with bulge loop, drug bucket upper opening, remaining
Face offers aperture, and the top of the extractor side connects inlet tube, and the lower part of the other side connects outlet tube, on extractor
Portion connects compressed air input pipe, and bottom is provided with the first electric heater unit, and extractor is connected in culture tank by outlet tube
Portion, the top of culture tank side is provided with plus bacterium mouthful, and culture tank is connect by supernatant delivery pipe with knockout drum one end, supernatant
It is provided with the first pressurizing delivery pump on delivery pipe pipeline, is disposed with first from the near to the remote away from supernatant delivery pipe on knockout drum
Seperation film, the second seperation film and third seperation film, the knockout drum other end connect separating liquid outlet pipe, the connection of the separating liquid outlet pipe other end
On the top of concentration tank side, concentration tank top offers steam (vapor) outlet, and lower part is provided with the second electric heater unit, under concentration tank
Portion is connected with concentrate delivery pipe, and the second pressurizing delivery pump, the concentrate delivery pipe are provided on concentrate delivery pipe pipeline
The other end is connected on the spray head at the top of spray dryer, and it is defeated that the gas gathering mask side on spray dryer top is connected with high temperature air
Pipe is sent, spray dryer lower part is provided with drug collecting vessel.
Preferably, the extractor bottom side is provided with blowdown valve.
Preferably, the lower part of the extractor side is provided with the first sample tap, and a side lower part of culture tank is provided with
Two sample taps, the lower part of concentration tank are provided with third sample tap.
Preferably, drug collecting vessel lower part is provided with trolley.
Preferably, the molecular cut off of first seperation film, the second seperation film and third seperation film is gradually reduced.
Preferably, the culture tank front is provided with sight glass, and described plus bacterium mouthful 25 ° -30 ° of inclination upwards adds on bacterium mouthful
It is provided with sealing cover.
The utility model has the following beneficial effects:
1. extractor top connects compressed air input pipe, bottom is provided with the first electric heater unit, passes through compressed air
It pressurizes to extractor, then heating device is carried out to extractor by the first electric heater unit, the extraction speed of drug can be accelerated
Degree, and improve the recovery rate of drug.
2. culture tank is arranged between extractor and knockout drum, specific microorganism fungus kind is added, microorganism is numerous in growth
During growing, there are decoloration and flocculating effect well to extracting solution, to improve the quality of product.
3. being disposed with the first seperation film, the second seperation film and from the near to the remote away from supernatant delivery pipe on knockout drum
Three seperation films, and molecular cut off is gradually reduced, in this way the supernatant after culture is separated gradually, to reach preferable
Separating effect improves the purity and quality of product.
Detailed description of the invention
Fig. 1 is a kind of structure of a kind of specific embodiment of bio-pharmaceuticals extraction purification device described in the utility model
Connection schematic diagram.
Fig. 2 is a kind of extraction of a kind of specific embodiment of bio-pharmaceuticals extraction purification device described in the utility model
Tank schematic diagram of internal structure.
Fig. 3 is a kind of sieve plate of a kind of specific embodiment of bio-pharmaceuticals extraction purification device described in the utility model
Structural schematic diagram.
The entitled 1- gland of appended drawing reference in figure, 2- compressed air input pipe, 3- inlet tube, 4- extractor, 5- first take
Sample mouth, 6- blowdown valve, the first electric heater unit of 7-, 8- outlet tube, the second sample tap of 9-, 10- supernatant delivery pipe, 11- first
Pressurizing delivery pump, 12- sealing cover, 13- add bacterium mouthful, 14- culture tank, 15- sight glass, 16- knockout drum, the first seperation film of 17-,
The second seperation film of 18-, 19- third seperation film, 20- separating liquid outlet pipe, 21- steam (vapor) outlet, 22- concentration tank, the sampling of 23- third
Mouthful, the second electric heater unit of 24-, 25- concentrate delivery pipe, 26- spray head, 27- gas gathering mask, 28- high temperature air delivery pipe, 29-
Spray dryer, 30- drug collecting vessel, 31- trolley, the second pressurizing delivery pump of 32-, 33- drug bucket, 34- bulge loop, 35- card
Connect ring, 36- sieve plate.
Specific embodiment
The following describes the utility model in further detail with reference to the accompanying drawings, to enable those skilled in the art referring to explanation
Book text can be implemented accordingly.
A kind of bio-pharmaceuticals extraction purification device, including extractor 4, culture tank 14, knockout drum 16, concentration tank 22 and spray
Mist drying machine 29, the hinged gland 1 in 4 top of extractor, extractor 4 are internally provided with sieve plate 36, are provided on sieve plate 36 convex
Ring 34,36 top of sieve plate are provided with drug bucket 33, and 33 bottom of drug bucket is provided with the clamping ring 35 matched with bulge loop 34, drug
33 upper openings of bucket, lap offer aperture, and the top of 4 side of extractor connects inlet tube 3, the lower part of the other side
Outlet tube 8 is connected, 4 top of extractor connects compressed air input pipe 2, and bottom is provided with the first electric heater unit 7, extractor 4
It is connected to 14 top of culture tank by outlet tube 8, the top of 14 side of culture tank is provided with plus bacterium mouthful 13, and culture tank 14 passes through upper
Clear liquid delivery pipe 10 is connect with 16 one end of knockout drum, and the first pressurizing delivery pump 11 is provided on 10 pipeline of supernatant delivery pipe, point
It is disposed with the first seperation film 17, the second seperation film 18 and third separation from the near to the remote away from supernatant delivery pipe 10 from tank 16
Film 19,16 other end of knockout drum connect separating liquid outlet pipe 20, and 20 other end of separating liquid outlet pipe is connected to the upper of 22 side of concentration tank
Portion, 22 top of concentration tank offer steam (vapor) outlet 21, and lower part is provided with the second electric heater unit 24, and 22 lower part of concentration tank is connected with
Concentrate delivery pipe 25 is provided with the second pressurizing delivery pump 32, the concentrate delivery pipe 25 on 25 pipeline of concentrate delivery pipe
The other end is connected on the spray head 26 at 29 top of spray dryer, and 27 side of gas gathering mask on 29 top of spray dryer is connected with height
Warm air delivery pipe 28,29 lower part of spray dryer are provided with drug collecting vessel 30.
In this embodiment, the present apparatus is primarily adapted for use in the extraction of drug ingedient resistant to high temperature, and extractor 4 is used for medicine
The extraction of object effective component, gland 1 are used for the sealing of extractor 4, and inlet tube 3 is used for the entrance of extracting solution, compressed air input
Pipe 2 is used for the input of compressed air, carries out pressurized operation to extractor 4, sieve plate 36 is convex for the supporting role to drug bucket 33
Ring 34 and clamping ring 35 are used for the positioning fixed function to drug bucket 33, and drug is limited in bucket by drug bucket 33, and aperture is used for
Drug ingedient is flowed out with extracting solution, and the setting of drug bucket 33, which facilitates, carries out quick separating, the first electricity for drug residue and extracting solution
For heating device 7 using being powered because high resistance causes fever to carry out heating work to extractor 4, drug ingedient is can be improved in heating pressurization
Extraction efficiency, save the time, reach preferable extraction effect, outlet tube 8 is trained for extracting solution to be transported in culture tank 14
It supports tank 14 to be used to carry out extracting solution decoloration and carry out flocculating effect to sundries, bacterium mouthful 13 is added to be used for the addition of microbial cells,
Supernatant delivery pipe 10 carries out mask work for the supernatant in culture tank 14 to be transported in knockout drum 16, the first seperation film
17, the second seperation film 18 and third seperation film 19 carry out separation gradually to supernatant, improve separating effect, the first pressure-increasing unit
Pump 11 is for pressurization work is carried out in knockout drum 16, to improve separative efficiency, separating liquid outlet pipe 20 to be for conveying separating liquid
To concentration tank 22, the second electric heater unit 24 makes to separate using being powered because high resistance causes fever to heat up concentration tank 22
Moisture evaporation in liquid, carries out preliminary concentration, and steam (vapor) outlet 21 is used for the discharge of vapor, and the second pressurizing delivery pump 32 is used for
Concentrate is subjected to pressurized operation, sprays concentrate in a manner of atomization in spray head 26, by contacting high temperature air delivery pipe
The high temperature air to come is conveyed, concentrate quick dewatering drying is made, obtains semi-finished product drug, spray dryer 29 is sprayed using pressure
Mist seasoning, structures and methods belong to the prior art, and it will not be described here.
4 bottom side of extractor is provided with blowdown valve 6, needs to carry out cleaning, blowdown valve after 4 use of extractor
6 are used for waste water discharge when extractor 4 cleans.
The lower part of 4 side of extractor is provided with the first sample tap 5, and a side lower part of culture tank 14 is provided with second and takes
Sample mouth 9, the lower part of concentration tank 22 are provided with third sample tap 23, and the setting of sample tap facilitates technologist each to drug extract
The sample detection in a stage reaches best technological effect with adjusting process parameter.
30 lower part of drug collecting vessel is provided with trolley 31, facilitates the transport of final drug.
The molecular cut off of first seperation film 17, the second seperation film 18 and third seperation film 19 is gradually reduced, and is passed through
Gradually concentrate is separated, available preferable separating effect.
14 front of culture tank is provided with sight glass 15, and 25 ° -30 ° of the inclination upwards of described plus bacterium mouthful 13 adds on bacterium mouthful 13
It is provided with sealing cover 12, sight glass 15 is used for the culture situation checked in culture tank 14, adds the upward inclination of bacterium mouthful 13 that can facilitate micro-
Biomass can smoothly enter into culture tank 14, and sealing cover 12 is used for adding bacterium mouthful 13 to be sealed.
It is not only in the description and the implementation although the embodiments of the present invention have been disclosed as above
Listed utilization, it can be applied to various fields suitable for the present invention completely, for those skilled in the art,
Other modifications may be easily implemented, therefore without departing from the general concept defined in the claims and the equivalent scope, this reality
It is not limited to specific details and legend shown and described herein with novel.
Claims (6)
1. a kind of bio-pharmaceuticals extraction purification device, it is characterised in that: including extractor (4), culture tank (14), knockout drum
(16), concentration tank (22) and spray dryer (29), the hinged gland in extractor (4) top (1), extractor (4) is internal to be set
It is equipped with sieve plate (36), is provided on sieve plate (36) bulge loop (34), sieve plate (36) top is provided with drug bucket (33), drug bucket (33)
Bottom is provided with the clamping ring (35) matched with bulge loop (34), drug bucket (33) upper opening, and lap offers aperture,
The top of extractor (4) side connects inlet tube (3), and the lower part of the other side connects outlet tube (8), extractor (4) top
It connects compressed air input pipe (2), bottom is provided with the first electric heater unit (7), and extractor (4) is connected by outlet tube (8)
On culture tank (14) top, the top of culture tank (14) side is provided with plus bacterium mouthful (13), and culture tank (14) is defeated by supernatant
It send pipe (10) to connect with knockout drum (16) one end, is provided with the first pressurizing delivery pump (11) on supernatant delivery pipe (10) pipeline,
It is disposed with the first seperation film (17), the second seperation film (18) from the near to the remote away from supernatant delivery pipe (10) on knockout drum (16)
With third seperation film (19), knockout drum (16) other end connects separating liquid outlet pipe (20), the connection of separating liquid outlet pipe (20) other end
On the top of concentration tank (22) side, concentration tank (22) top offers steam (vapor) outlet (21), and lower part is provided with the second electric heating
Device (24), concentration tank (22) lower part are connected with concentrate delivery pipe (25), and is provided on concentrate delivery pipe (25) pipeline
Two pressurizing delivery pumps (32), concentrate delivery pipe (25) other end are connected to the spray head (26) at the top of spray dryer (29)
On, gas gathering mask (27) side on spray dryer (29) top is connected with high temperature air delivery pipe (28), spray dryer (29)
Lower part is provided with drug collecting vessel (30).
2. a kind of bio-pharmaceuticals extraction purification device according to claim 1, it is characterised in that: the extractor (4)
Bottom side is provided with blowdown valve (6).
3. a kind of bio-pharmaceuticals extraction purification device according to claim 1, it is characterised in that: the extractor (4)
The lower part of side is provided with the first sample tap (5), and a side lower part of culture tank (14) is provided with the second sample tap (9), concentration tank
(22) lower part is provided with third sample tap (23).
4. a kind of bio-pharmaceuticals extraction purification device according to claim 1, it is characterised in that: the drug collecting vessel
(30) lower part is provided with trolley (31).
5. a kind of bio-pharmaceuticals extraction purification device according to claim 1, it is characterised in that: first seperation film
(17), the molecular cut off of the second seperation film (18) and third seperation film (19) is gradually reduced.
6. a kind of bio-pharmaceuticals extraction purification device according to claim 1, it is characterised in that: the culture tank (14)
Front is provided with sight glass (15), and described plus bacterium mouthful (13) 25 ° -30 ° of inclination upwards adds and is provided with sealing cover on bacterium mouthful (13)
(12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820938248.6U CN208583015U (en) | 2018-06-19 | 2018-06-19 | A kind of bio-pharmaceuticals extraction purification device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820938248.6U CN208583015U (en) | 2018-06-19 | 2018-06-19 | A kind of bio-pharmaceuticals extraction purification device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208583015U true CN208583015U (en) | 2019-03-08 |
Family
ID=65536560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820938248.6U Expired - Fee Related CN208583015U (en) | 2018-06-19 | 2018-06-19 | A kind of bio-pharmaceuticals extraction purification device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208583015U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114210089A (en) * | 2021-10-25 | 2022-03-22 | 福州一诺维生物科技有限公司 | Process and device for preparing biological extract |
-
2018
- 2018-06-19 CN CN201820938248.6U patent/CN208583015U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114210089A (en) * | 2021-10-25 | 2022-03-22 | 福州一诺维生物科技有限公司 | Process and device for preparing biological extract |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190308 Termination date: 20190619 |
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| CF01 | Termination of patent right due to non-payment of annual fee |