CN208537421U - Full-automatic chemiluminescence immunoassay analysis meter - Google Patents
Full-automatic chemiluminescence immunoassay analysis meter Download PDFInfo
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- CN208537421U CN208537421U CN201821270582.5U CN201821270582U CN208537421U CN 208537421 U CN208537421 U CN 208537421U CN 201821270582 U CN201821270582 U CN 201821270582U CN 208537421 U CN208537421 U CN 208537421U
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Abstract
The utility model provides a kind of Full-automatic chemiluminescence immunoassay analysis meter, including body and the reaction cup storage device, sample storage device, turntable incubating device, refrigerating plant, reaction cup grabbing device, magnetic separating device, optical detection acquisition device, substrate solution storage device, reagent storage means, acquisition device, recyclable device, temperature control device and the control system that are separately positioned on body；Reaction cup storage device, turntable incubating device, magnetic separating device and optical detection acquisition device are arranged side by side, and it is located at the same side, after reaction cup grabbing device grabs the reaction cup in reaction cup storage device, reaction cup is enable to move in a straight line between magnetic separating device, turntable incubating device and optical detection acquisition device；The locations of structures of each device of this programme is laid out operation, reduces the occupied space of each component.
Description
Technical field
The utility model relates to the field of medical instrument technology, more particularly, to a kind of automatic chemiluminescence immunoassay
Instrument.
Background technique
Currently, the Major Clinical function of Full-automatic chemiluminescence immunoassay analysis meter are as follows: Quantitative in vitro detects human serum, blood
The content of a variety of projects such as slurry, whole blood or various albumen, antigen in urine, for clinical disease diagnosis, prevent, control
It treats and health monitoring provides really and accurately data foundation.
To meet requirement of the current medical industry to the POCT of inspection, realization quickly obtains accurate inspection result, removes
Many and diverse operation sequence reduces the influence of manual operation bring error or mistake to result, improves test speed, full-automatic
Learn the inexorable trend that luminescence immunoassay instrument is current Instrument Development.
Existing Full-automatic chemiluminescence immunoassay analysis meter currently on the market, it is most of to belong to large-scale cabinet type analysis
Instrument.For example the Immulite 1000 of Siemens, the Products such as COBAS E411 of Roche, instrument are all cabinet type large sizes
Equipment, length are more than more than 1 meter.The case where for limited spaces such as hospital clinical detection, emergency treatments, is not suitable for very much.
Utility model content
The purpose of this utility model is to provide a kind of Full-automatic chemiluminescence immunoassay analysis meters, at least to solve existing skill
One of technical problem present in art.
To achieve the goals above, the utility model provides following technical scheme；
Full-automatic chemiluminescence immunoassay analysis meter provided by the utility model, including body and it is separately positioned on the body
On reaction cup storage device, sample storage device, turntable incubating device, refrigerating plant, reaction cup grabbing device, Magneto separate dress
It sets, optical detection acquisition device, substrate solution storage device, reagent storage means, sample/reagent acquisition device, recyclable device, temperature
Control device and control system；Above-mentioned each device is electrically connected with control system respectively；The refrigerating plant and the reagent store
Device is connected, for freezing to the reagent storage means；The acquisition device close to the sample storage device and
The reagent storage means setting, the control system control the acquisition device to the sample on the sample storage device
And/or the reagent in the reagent storage means is acquired；The turntable incubating device and magnetic separating device are arranged side by side, institute
State the same side that reaction cup grabbing device is located at the turntable incubating device and magnetic separating device, the reaction cup grabbing device from
The crawl of empty reaction cup is moved on the turntable incubating device by reaction cup storage device, the sample that the acquisition device will be taken
And/or reagent is placed in reaction cup, the temperature control device is arranged in the turntable incubating device, for being incubated for the turntable
The temperature of device carries out, and when the reaction cup is after the turntable incubating device is incubated for, the reaction cup grabbing device is by the reaction
Cup crawl is placed in the magnetic separating device, and the magnetic separating device is connected with the substrate solution storage device, by described
The reaction cup that magnetic separating device carries out Magneto separate is grabbed by the reaction cup grabbing device to optics inspection after filling substrate solution
It surveys and carries out optical detection acquisition in acquisition device, the recyclable device is for recycling the reaction cup after optical detection.
The reaction cup storage device, turntable incubating device, magnetic separating device are arranged side by side, the reaction cup grabbing device
It is described positioned at the same side of the reaction cup storage device, turntable incubating device, magnetic separating device and optical detection acquisition device
After reaction cup grabbing device grabs the reaction cup in reaction cup storage device, reaction cup is enable to incubate in magnetic separating device, turntable
It educates and is moved in a straight line between device and optical detection acquisition device.
The sample storage device, the reagent storage means are arranged side by side, and are located at the two of the turntable incubating device
Side, so that the line between the sample storage device, the reagent storage means and turntable incubating device forms a triangle
Shape, the control system control the sample/reagent acquisition device on the sample storage device sample and/or reagent deposit
Reagent on storage device is added directly into the reaction cup of the magnetic separating device after being acquired.
In the above-mentioned technical solutions, further, the sample storage device includes fixed bracket, rotating electric machine, synchronization
Wheel, synchronous belt and sample disk, the bit of storage for storing sample tube is provided on the sample disk, and the rotating electric machine is fixed on
On the fixed bracket, and the output end of the rotating electric machine is sequentially connected by synchronous belt and synchronizing wheel, and the synchronizing wheel is solid
It is scheduled on the sample disk.
In any of the above-described technical solution, further, the acquisition device include rack, lifting device, rotating device,
Liquid level sensor and acquisition needle；
The lifting device and the rotating device are separately positioned in the rack, and the guide rod of the lifting device is logical
It crosses swing arm to connect with the acquisition needle, the rotating device and the guide rod are sequentially connected, and the rotating device can make institute
Guide rod rotation is stated, and then drives the swing arm rotation, the lifting device can be such that the guide rod does along the rack
Elevating movement；
The liquid level sensor setting is electrically connected in the swing arm, and with the acquisition needle and lifting device, when
When liquid level sensor detects that the acquisition needle is contacted to liquid level, the liquid level sensor, which controls the lifting device, to be stopped
Operating.
In any of the above-described technical solution, further, the rack includes pedestal, riser and transverse slat, the riser
Both ends are connected with the pedestal and transverse slat respectively, and between the pedestal and transverse slat；The lifting device includes driving
Portion, driving section and sliding block, the driving portion setting on the base, are provided with slide opening on the riser, the driving portion
Output end passes through the slide opening and is connected with the driving section；The sliding block is set in the bottom end of the guide rod, and with it is described
Driving section is connected, and the upper end of the guide rod passes through the transverse slat and is connected with the rotating device, and the driving portion can
The driving section is driven to be driven, to drive the sliding block to move up and down, so that the guide rod be made to move up and down.
In any of the above-described technical solution, further, the acquisition device further includes anti-collision protection device；
The anti-collision protection device includes optocoupler baffle, the second photoelectric sensor and spring；The optocoupler baffle with it is described
The upper end of sampling needle is connected, and is pressed in the swing arm by the spring；Second photoelectric sensor is fixed by the bracket
It is electrically connected in the swing arm, and with the driving portion, when the lower end of the sampling needle bumps against barrier, the sampling needle
Upper end jack up the optocoupler baffle, at this point, the spring-compressed, the optocoupler baffle blocks second photoelectric sensor
Optocoupler, second photoelectric sensor control the driving portion and stop working.
In any of the above-described technical solution, further, the acquisition device is used for collecting sample and/or reagent, acquisition
Device can be a sample collecting device and a reagent acquisition device, be respectively used to collecting sample and reagent；Or
Sample and the combined integrated acquisition device of reagent.
In any of the above-described technical solution, further, the reaction cup grabbing device include fixing seat, driving device,
Cam chair, guide holder, the first calvus and the second calvus；
The driving device, guide holder are separately fixed in the fixing seat, the cam chair and the driving device
Output shaft is connected, and cam mechanism, first calvus and the second calvus are provided on the cam chair and is slided by guide rod
Setting be respectively arranged with the company matched with the cam mechanism in guide holder, and on first calvus and the second calvus
Socket part；
It drives the cam chair to rotate when the rotation of the output axial direction first direction of the driving device, and then makes described convex
Wheel mechanism drives first calvus and the second calvus to relatively move on the guide rod, to grab reaction cup；When the drive
It drives the cam chair to rotate when the output axial direction second direction rotation of dynamic device, and then makes described in the cam mechanism driving the
One calvus and the second calvus are mutually separate mobile on the guide rod, to decontrol the reaction cup.
In any of the above-described technical solution, further, the reaction cup grabbing device further includes detection device；
Detection device setting on the fixing seat, for detecting the turned position of the cam chair, when detecting
When the cam chair turns to predeterminated position, the detection device controls the driving device and stops.
In any of the above-described technical solution, further, the magnetic separating device includes rack, waste discharge needle, cleaning needle, biography
Send mechanism, magnet assemblies and the storage block for placing response cup；
The transport mechanism is arranged in the rack, and the storage block is connected with the transport mechanism, the transmission
Mechanism is used to the storage block being sent to waste discharge position and cleaning position in the rack, and is provided at the cleaning position the
One evenly mixing device, the magnet assemblies are arranged at the waste discharge position, for the magnetic bead in the reaction cup on the storage block
Carry out magnetic suck；
The waste discharge needle and the cleaning needle are separately positioned on needle stand, and corresponding setting in the waste discharge position and
The top of cleaning position, and the needle stand is arranged in the rack by lifting device, the lifting device drives the needle stand
Do lifting moving；
It further include substrate needle and the second evenly mixing device；
The substrate needle is arranged in the rack by bracket, and is located at the substrate storage position of the rack；
Second evenly mixing device is arranged at the substrate storage position, and the reaction cup can be in the transport mechanism
Transmission effect is displaced downwardly to the substrate storage position.
In any of the above-described technical solution, further, the optical detection acquisition device includes optical detecting module, adopts
Collect module and carrier；
It is provided with the installation position for accommodating reaction cup on the carrier, and corresponding with the reaction cup described holds
Light-emitting window is provided on the side wall of load plate；
The optical detecting module corresponds to the light-emitting window setting, for receiving the sample in reaction cup from the light-emitting window
The light irradiated, and optical detection is carried out to the sample, and the optical detecting module is electrically connected with the acquisition module,
The result that the optical detecting module will test is sent to the acquisition module.
In any of the above-described technical solution, further, the refrigerating plant includes cooling piece, temperature sensor and temperature
Switch, the cooling piece is arranged at the bit of storage of the reagent storage device, for freezing to reagent, the cooling piece
It is connected respectively with the temperature sensor and temperature switch, and the temperature sensor is connected with the temperature switch, when
The temperature that the temperature sensor detects the cooling piece reaches preset value, and the temperature switch controls the cooling piece and stops work
Make.
By adopting the above technical scheme, the utility model has the following beneficial effects:
Full-automatic chemiluminescence immunoassay analysis meter provided by the utility model, the reaction cup storage device, turntable are incubated for
Device, magnetic separating device are arranged side by side, and the reaction cup grabbing device is located at the reaction cup storage device, turntable is incubated for dress
It sets, the same side of magnetic separating device and optical detection acquisition device, the reaction cup grabbing device grabs reaction cup storage device
After interior reaction cup, reaction cup is enable to do between magnetic separating device, turntable incubating device and optical detection acquisition device directly
Line movement, the sample storage device, the reagent storage means are arranged side by side, and are located at the two of the turntable incubating device
Side, so that the line between the sample storage device, the reagent storage means and turntable incubating device forms a triangle
Shape, the control system control the acquisition device on the sample storage device sample and/or reagent storage means on
Reagent be acquired after be added directly into the reaction cup of the magnetic separating device, the locations of structures of each device is laid out fortune
Row, reduces the occupied space of each component, makes the more compact of each device layout, reduces the occupied space of integral device.
The additional aspect and advantage of the utility model will become obviously in following description section, or practical new by this
The practice of type is recognized.
Detailed description of the invention
It below will be right in order to illustrate more clearly of specific embodiment of the present invention or technical solution in the prior art
Specific embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, it is described below
In attached drawing be that some embodiments of the utility model are not paying creativeness for those of ordinary skill in the art
Under the premise of labour, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is the body schematic diagram of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model；
Fig. 2 is the decomposition texture schematic diagram of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model；
Fig. 3 is the knot of the reagent storage means of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Structure schematic diagram；
Fig. 4 is the reaction cup storage device of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Structural schematic diagram；
Fig. 5 is the knot of the sample storage device of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Structure schematic diagram；
Fig. 6 is the knot of the turntable incubating device of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Structure schematic diagram；
Fig. 7 is the reaction cup grabbing device of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Structural schematic diagram；
Fig. 8 is the reaction cup grabbing device of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
A part of structural schematic diagram；
Fig. 9 is sample/reagent acquisition dress of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
The structural schematic diagram set；
Figure 10 is sample/reagent acquisition dress of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
The partial structural diagram set；
Figure 11 is that the optical detection of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model acquires dress
The structural schematic diagram set；
Figure 12 is the knot of the magnetic separating device of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Structure schematic diagram；
Figure 13 is the body fuselage that removes of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Schematic perspective view；
Figure 14 is the body fuselage that removes of Full-automatic chemiluminescence immunoassay analysis meter provided by the embodiment of the utility model
Overlooking structure diagram.
Appended drawing reference:
1- body；2- reaction cup storage device；3- sample storage device；301- fixes bracket；302- rotating electric machine；
303- sample disk；4- turntable incubating device；5- reaction cup grabbing device；501- fixing seat；502- driving device；503- cam
Seat；504- guide holder；The first calvus of 505-；The second calvus of 506-；507- transmission mechanism；6- magnetic separating device；601- waste discharge
Needle；602- cleaning needle；603- transport mechanism；604- magnet assemblies；605- stores block；606- lifting device；607- first is mixed
Device；The second evenly mixing device of 608-；7- optical detection acquisition device；701- optical detecting module；702- carrier；8- substrate
Liquid storage device；9- acquisition device；901- sliding block；902- guide rod；903- driving portion；904- acquires needle；905- level detection
Device；906- rotating device；The second photoelectric sensor of 907-；908- swing arm；909- optocoupler baffle；10- reagent storage means.
Specific embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with attached drawing, it is clear that described
Embodiment is the utility model a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, originally
Field those of ordinary skill every other embodiment obtained without making creative work belongs to practical
Novel protected range.It should be noted that in the absence of conflict, the feature in embodiments herein and embodiment can
To be combined with each other.
It is in the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", " perpendicular
Directly ", the orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, and is only
For ease of description the utility model and simplify description, rather than the device or element of indication or suggestion meaning must have it is specific
Orientation, be constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.In addition, term " the
One ", " second ", " third " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified
Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally
Connection；It can be mechanical connection, be also possible to be electrically connected；Can be directly connected, can also indirectly connected through an intermediary,
It can be the connection inside two elements.For the ordinary skill in the art, above-mentioned art can be understood with concrete condition
The concrete meaning of language in the present invention.
Explanation is further explained to the utility model below with reference to specific embodiment.
Embodiment one
As shown in Fig. 1-Figure 14, Full-automatic chemiluminescence immunoassay analysis meter provided in this embodiment, including body 1 and difference
Reaction cup storage device 2, sample storage device 3, turntable incubating device 4, refrigerating plant, reaction on the body 1 are set
Cup grabbing device 5, magnetic separating device 6, optical detection acquisition device 7, substrate solution storage device 8, reagent storage means 10, acquisition
Device 9, recyclable device, temperature control device and control system；Above-mentioned each device is electrically connected with control system respectively；
The refrigerating plant is connected with the reagent storage means 10, for making to the reagent storage means 10
It is cold；The acquisition device 9 is arranged close to the sample storage device 3 and the reagent storage means 10, the control system control
Reagent of the acquisition device 9 to the sample on the sample storage device 3 and/or in the reagent storage means 10 is made to carry out
Acquisition；The turntable incubating device 4 and magnetic separating device 6 are arranged side by side, and the reaction cup grabbing device 5 is located at the turntable and incubates
The same side of device 4 and magnetic separating device 6 is educated, the reaction cup grabbing device 5 grabs empty reaction cup from reaction cup storage device 2
It takes and is moved on the turntable incubating device 4, the sample taken and/or reagent are placed in reaction cup by the acquisition device 9, institute
It states temperature control device to be arranged in the turntable incubating device 4, be controlled for the temperature to the turntable incubating device 4, when
For the reaction cup after the turntable incubating device 4 incubation, reaction cup crawl is placed the magnetic by the reaction cup grabbing device 5
In separator 6, the magnetic separating device 6 is connect with the substrate solution storage device phase 8, by the magnetic separating device 6 into
By the reaction cup grabbing device 5 crawl to the optical detection acquisition device 7 after the reaction cup filling substrate solution of row Magneto separate
Interior progress optical detection acquisition, the recyclable device is for recycling the reaction cup after optical detection.
As shown in Figure 13 and Figure 14, the reaction cup storage device 2, turntable incubating device 4, magnetic separating device 6 are set side by side
It sets, the reaction cup grabbing device is located at the reaction cup storage device 2, turntable incubating device 4, magnetic separating device 6 and optics
The same side of acquisition device 7 is detected, after the reaction cup grabbing device grabs the reaction cup in reaction cup storage device 2, is made anti-
Answer cup that can move in a straight line between magnetic separating device 6, turntable incubating device 4 and optical detection acquisition device 7.
As shown in figure 14, the sample stores 3 devices, the reagent storage means 10 are arranged side by side, and is located at described turn
The two sides of disk incubating device 4 so that the sample store 3 devices, the reagent storage means 10 and turntable incubating device 4 it
Between line form a triangle, the acquisition device 9 is located at the sample storage device, the reagent storage means and institute
State the centre of turntable incubating device 4, it is preferred that the acquisition device 9 is located at the center of the triangle；Preferably, described to adopt
Acquisition means 9 are located at the center of the triangle.In one embodiment, when the acquisition device 9 set there are two when, one of them
Acquisition device is located at the centre of the sample storage device 3 and the turntable incubating device 4, another acquisition device is located at institute
State the centre of reagent storage means 10 and the turntable incubating device 4.The control system controls the acquisition device 9 to described
The reagent on sample and/or reagent storage means 10 on sample storage device 3 is added directly into the magnetic point after being acquired
In reaction cup from device 6.
When operation, sample tube is placed on reaction cup storage device 2 by acquisition device 9 and samples reaction cup grabbing device
Empty reaction cup is pressed from both sides the acquired absorption of device 9 from reaction cup storehouse by 5 to be put into the turntable incubating device 4 equipped with sample through row incubation instead
It should react, reaction cup is put into magnetic separating device 6 by reaction cup grabbing device 5, it is acted through row Magneto separate, after the completion of Magneto separate,
Substrate clamping jaw is injected to clamp reaction cup to optical detection acquisition device 7, the 7 collection result data waste discharge of optical detection acquisition device
Mechanism, which will test waste liquid in the reaction cup of completion cup is discharged, lowers into useless cup recycling box, such loop cycle, and realization is held
Continue continuous test sample.
In an optional embodiment of above-described embodiment, as shown in figure 5, the sample storage device 3 includes solid
Fixed rack 301, rotating electric machine 302, synchronizing wheel, synchronous belt and sample disk 303 are provided with for storing on the sample disk 303
The bit of storage of sample tube, the rotating electric machine 302 is fixed on the fixed bracket 301, and the rotating electric machine 302 is defeated
Outlet is sequentially connected by synchronous belt and synchronizing wheel, and the synchronizing wheel is fixed on the sample disk 303, and storage transmission facilitates letter
It is single.
In an optional embodiment of above-described embodiment, as shown in Figure 9 and Figure 10, the acquisition device 9 includes
Rack, lifting device 606, rotating device 906, liquid level sensor 905 and acquisition needle 904；
The lifting device 606 and the rotating device 906 are separately positioned in the rack, the lifting device 606
Guide rod 902 connect with the acquisition needle 904 by swing arm 908, the rotating device 906 and the guide rod 902 transmission
Connection, the rotating device 906 can be such that the guide rod 902 rotates, and then the swing arm 908 is driven to rotate, the lifting
Device 606 can be such that the guide rod 902 moves up and down along the rack；
The liquid level sensor 905 is arranged in the swing arm 908, and with the acquisition needle 904 and lifting device 606
It is electrically connected, when liquid level sensor 905 detects the contact of acquisition needle 904 to liquid level, the liquid level sensor 905
The lifting device 606 is controlled to shut down.And then be sampled, after sampling, sampling needle can be rotated to detection device
Reaction tray at, then sample in lower general who has surrendered's sampling needle spits in reaction tray, then swing arm 908 can also be rotated to cleaning
Pond drops in service sink and is cleaned.
On the basis of the above embodiments, the rack includes pedestal, riser and transverse slat, the both ends of the riser respectively with
The pedestal is connected with transverse slat, and between the pedestal and transverse slat；The lifting device 606 includes driving portion 903, passes
Dynamic portion and sliding block 901, the setting of driving portion 903 on the base, are provided with slide opening, the driving portion on the riser
903 output end passes through the slide opening and is connected with the driving section；The sliding block 901 is set in the bottom of the guide rod 902
End, and be connected with the driving section, the upper end of the guide rod 902 passes through the transverse slat and is connected with the rotating device 906
It connects, the driving portion 903 can drive the driving section to be driven, to drive the sliding block 901 to move up and down, to make described lead
It is moved up and down to bar 902.
Optionally, the acquisition device 9 further includes anti-collision protection device；
The anti-collision protection device includes optocoupler baffle 909, the second photoelectric sensor 907 and spring；The optocoupler baffle
909 are connected with the upper end of the sampling needle, and are pressed in the swing arm 908 by the spring；Second photoelectric sensor
907 are fixed by the bracket in the swing arm 908, and are electrically connected with the driving portion 903, when the lower end of the sampling needle is hit
When to barrier, the upper end of the sampling needle jacks up the optocoupler baffle 909, at this point, the spring-compressed, the optocoupler baffle
909 block the optocoupler of second photoelectric sensor 907, and second photoelectric sensor 907 controls the driving portion 903 and stops
Only work.It avoids at work, the case where sampling needle is damaged by collision.
It should be noted that the acquisition device 9 can be a sample collecting device or reagent acquisition device or sample
The combined integrated acquisition device with reagent.
In an optional embodiment of above-described embodiment, as shown in Figure 7 and Figure 8, the reaction cup grabbing device
Including fixing seat 501, driving device 502, cam chair 503, guide holder 504, the first calvus 505 and the second calvus 506；
The driving device 502, guide holder 504 are separately fixed in the fixing seat 501, the cam chair 503 and institute
The output shaft for stating driving device 502 is connected, and cam mechanism, 505 He of the first calvus are provided on the cam chair 503
The setting that second calvus 506 is slided by guide rod 902 is in guide holder 504, and first calvus 505 and the second calvus
The interconnecting piece matched with the cam mechanism is respectively arranged on 506；
It drives the cam chair 503 to rotate when the rotation of the output axial direction first direction of the driving device 502, and then makes
First calvus 505 and the second calvus 506 described in the cam mechanism driving relatively move on the guide rod 902, with crawl
Reaction cup；It drives the cam chair 503 to rotate when the rotation of the output axial direction second direction of the driving device 502, and then makes
First calvus 505 described in the cam mechanism driving is mutually separate mobile on the guide rod 902 with the second calvus 506, to put
Open the reaction cup.
When specific operation, the cam chair 503 is driven when the rotation of the output axial direction first direction of the driving device 502
Rotation, and then keep the first calvus 505 and the second calvus 506 described in the cam mechanism driving opposite on the guide rod 902
It is mobile, to grab reaction cup；
It drives the cam chair 503 to rotate when the rotation of the output axial direction second direction of the driving device 502, and then makes
First calvus 505 described in the cam mechanism driving is mutually separate mobile on the guide rod 902 with the second calvus 506, to put
Open the reaction cup.Structure is simple, and precisely, no intermediate transmission is compact-sized small and exquisite for movement, and transmission efficiency is high, ensure that movement
The reliability in the output service life and transmission of power source, meanwhile, elliptical gear is small, avoids the movement nothing of electromagnet in the prior art
Damping buffering causes reaction cup to impact big problem.In addition, cam drive and guiding vulnerable part guide sleeve and guide rod 902 use
Split structure is convenient for later period breakdown maintenance and replacement, is maintained easily；By the detection of photoelectric sensor, product ensure that
Operational reliability and stability；Guide rod 902 is arranged using the layout of triangle, keeps its guiding more reliable and more stable；Lubricating sleeve
Setting can to avoid caused by the friction between guide rod 902 and calvus wear, prolong its service life, reduce friction damage
Consume efficiency and mechanical energy.
Optionally, the reaction cup grabbing device further includes detection device；
The detection device is arranged in the fixing seat 501, for detecting the turned position of the cam chair 503, when
When detecting that the cam chair 503 turns to predeterminated position, the detection device controls the driving device 502 and stops.
In this embodiment, it by the setting of detection device, and is electrically connected with driving device 5022, meanwhile, pass through
The position of baffle can be set in setting to predeterminated position, is in baffle when blocking the first photoelectric sensor and exactly grabs
The position of reaction cup, detection when on the one hand having reflected to reaction cup crawl, is on the other hand effectively controlled driving dress again
Set 502 rotation.
In addition, the reaction cup grabbing device further includes transmission mechanism 507；The transmission mechanism 507 and the fixation
501 phases of seat are slidably connected, so that the fixing seat 501 can move on the transmission mechanism 507；The transmission mechanism 507
Including the first transmission mechanism and the second transmission mechanism, first transmission mechanism and the second transmission mechanism respectively with the fixing seat
501 phases are slidably connected, and the fixing seat 501 is in the moving direction of first transmission mechanism and in second transmission mechanism
Moving direction it is orthogonal.
In another optional embodiment of above-described embodiment, as shown in figure 12, the magnetic separating device 6 includes machine
Frame, waste discharge needle 601, cleaning needle 602, transport mechanism 603, magnet assemblies 604 and the storage block 605 for placing response cup；
The transport mechanism 603 is arranged in the rack, and the storage block 605 is connected with the transport mechanism 603,
The transport mechanism 603 is used to for the storage block 605 being sent to waste discharge position and cleaning position in the rack, and described clear
The first evenly mixing device 607 is provided at washing, the magnet assemblies 604 are arranged at the waste discharge position, for the storage
Magnetic bead in reaction cup on block 605 carries out magnetic suck；
The waste discharge needle 601 and the cleaning needle 602 are separately positioned on needle stand, and corresponding setting is in the row
The top of deposal and cleaning position, and the needle stand is arranged in the rack by lifting device 606, the lifting device 606
The needle stand is driven to do lifting moving；When operation, transport mechanism 603 is sent to waste discharge position, magnet assemblies 604 for block 605 is stored
By the magnetic bead absorption in the reaction cup in storage position, lifting device 606 drops to waste discharge needle 601 in reaction cup, to waste liquid
It draws and excludes, complete and then storage block 605 is moved to cleaning position, cleaning needle 602 is dropped to reaction by lifting device 606
In cup, cleaning solution is placed, carries out shaking mixing to reaction cup by the first evenly mixing device 607, then returns the progress of waste discharge position
Waste discharge, cleaning mixes waste discharge back and forth.
It further include substrate needle and the second evenly mixing device 608；
The substrate needle is arranged in the rack by bracket, and is located at the substrate storage position of the rack；
Second evenly mixing device 608 is arranged at the substrate storage position, and the reaction cup can be in the conveyer
The transmission effect of structure 603 is displaced downwardly to the substrate storage position.
It in this embodiment, will under the action of transport mechanism 603 for the reaction cup after above-mentioned final cleaning waste discharge
Storage block 605 is moved at substrate storage position, is directed in reaction cup by substrate and quantitative substrate, the substrate of optional milliliter is added
It is added, the reaction cup for opening 608 pairs of the second evenly mixing device addition substrates later carries out friction concussion and mixes, and can take away light
Learn detection.
In addition, it is necessary to explanation, the needle mouth of waste discharge needle 601 is slope mouthful, slope mouthful at contact to reaction cup bottom,
Waste liquid can be all discharged, not have residual, optionally, the tip diameter of waste discharge needle 601 can choose 0.8 millimeter, in
Diameter is 0.5mm (millimeter)；In addition, the setting of smooth erosion resistant coating, can be improved the non-stick and corrosion resistance of waste discharge needle 601, most
The service performance of the raising needle of big degree prevents from hanging liquid, gets rid of the generation of the phenomenon that liquid；Smooth erosion resistant coating is preferably teflon material
Layer, utility model people has shown that through test of many times research, by teflon material be coated in the bottom of waste discharge needle 601 from needle point up 40~
Teflon material layer is formed in the range of 60mm (preferably 50mm), can be better protected from and be hung liquid, gets rid of the generation of the phenomenon that liquid,
Cost is relatively low simultaneously.
In an optional embodiment of above-described embodiment, as shown in figure 11, the optical detection acquisition device 7 is wrapped
Include optical detecting module 701, acquisition module and carrier 702；
The installation position for accommodating reaction cup, and institute corresponding with the reaction cup are provided on the carrier 702
It states and is provided with light-emitting window on the side wall of carrier 702；
The corresponding light-emitting window setting of the optical detecting module 701, for receive the sample in reaction cup from it is described go out
The light that optical port irradiates, and optical detection, and the optical detecting module 701 and the acquisition module phase are carried out to the sample
Electrical connection, the result that the optical detecting module 701 will test are sent to the acquisition module.Acquisition module tie to detection
Fruit is recorded, and structure is simple, is occupied little space, and it is convenient and simple to survey light.
In an optional embodiment of above-described embodiment, the refrigerating plant includes cooling piece, temperature sensor
And temperature switch, the cooling piece are arranged at the bit of storage of the reagent storage device, it is described for freezing to reagent
Cooling piece is connected with the temperature sensor and temperature switch respectively, and the temperature sensor is connected with the temperature switch
It connects, when the temperature that the temperature sensor detects the cooling piece reaches preset value, the temperature switch controls the cooling piece
It stops working, enables reagent long-term preservation, do not need the work such as frequent reclaim reagent.
Finally, it should be noted that the above various embodiments is only to illustrate the technical solution of the utility model, rather than it is limited
System；Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should
Understand: it is still possible to modify the technical solutions described in the foregoing embodiments, or to some or all of
Technical characteristic is equivalently replaced；And these are modified or replaceed, it does not separate the essence of the corresponding technical solution, and this is practical new
The range of each embodiment technical solution of type.In addition, it will be appreciated by those of skill in the art that although some implementations described herein
Example includes certain features included in other embodiments rather than other feature, but the group of the feature of different embodiments is desirable
Taste within the scope of the utility model and form different embodiments.For example, in claims above, institute
Claimed embodiment it is one of any can in any combination mode come using.It is disclosed in the background technology part
Information is merely intended to deepen the understanding to the general background technology of the utility model, and is not construed as recognizing or with any shape
Formula implies that the information constitutes the prior art known to those skilled in the art.
Claims (13)
1. a kind of Full-automatic chemiluminescence immunoassay analysis meter, which is characterized in that including body and be separately positioned on the body
Reaction cup storage device, sample storage device, turntable incubating device, refrigerating plant, reaction cup grabbing device, Magneto separate dress
Set, optical detection acquisition device, substrate solution storage device, reagent storage means, acquisition device, recyclable device, temperature control device and
Control system；Above-mentioned each device is electrically connected with control system respectively；The refrigerating plant is connected with the reagent storage means
It connects, for freezing to the reagent storage means；The acquisition device is close to the sample storage device and the reagent
Storage device setting, the control system control the acquisition device to sample on the sample storage device and/or described
Reagent in reagent storage means is acquired；The turntable incubating device and magnetic separating device are arranged side by side, the reaction cup
Grabbing device is located at the same side of the turntable incubating device and magnetic separating device, and the reaction cup grabbing device is deposited from reaction cup
The crawl of empty reaction cup is moved on the turntable incubating device by storage device, and the acquisition device is by the sample taken and/or examination
Agent is placed in reaction cup；The temperature control device is arranged in the turntable incubating device, for the turntable incubating device
Temperature carries out, and when the reaction cup is after the turntable incubating device is incubated for, the reaction cup grabbing device grabs the reaction cup
It places in the magnetic separating device, the magnetic separating device is connected with the substrate solution storage device, by the Magneto separate
The reaction cup that device carries out Magneto separate is grabbed by the reaction cup grabbing device to optical detection acquisition after filling substrate solution
Optical detection acquisition is carried out in device, the recyclable device is for recycling the reaction cup after optical detection.
2. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the reaction cup storage dress
Set, turntable incubating device, magnetic separating device be arranged side by side, the reaction cup grabbing device be located at the reaction cup storage device,
The same side of turntable incubating device, magnetic separating device, optical detection acquisition device, the reaction cup grabbing device grab reaction cup
After reaction cup in storage device, enable reaction cup in magnetic separating device, turntable incubating device and optical detection acquisition device
Between move in a straight line；
The sample storage device, the reagent storage means are arranged side by side, and are located at the two sides of the turntable incubating device, with
The line between the sample storage device, the reagent storage means and turntable incubating device is set to form a triangle, institute
It states control system and controls the acquisition device to the sample on the sample storage device and/or the reagent in reagent storage means
It is added directly into after being acquired in the reaction cup of the magnetic separating device.
3. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that
The sample storage device includes fixing bracket, rotating electric machine, synchronizing wheel, synchronous belt and sample disk, on the sample disk
It is provided with the bit of storage for storing sample tube, the rotating electric machine is fixed on the fixed bracket, and the rotating electric machine
Output end be sequentially connected by synchronous belt and synchronizing wheel, the synchronizing wheel is fixed on the sample disk.
4. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that
The acquisition device includes rack, lifting device, rotating device, liquid level sensor and acquisition needle；
The lifting device and the rotating device are separately positioned in the rack, and the guide rod of the lifting device passes through pendulum
Arm is connect with the acquisition needle, and the rotating device and the guide rod are sequentially connected, and the rotating device can make described lead
It is rotated to bar, and then drives the swing arm rotation, the lifting device can be such that the guide rod goes up and down along the rack
Movement；
The liquid level sensor setting is electrically connected in the swing arm, and with the acquisition needle and lifting device, works as liquid level
When detection device detects that the acquisition needle is contacted to liquid level, the liquid level sensor controls the lifting device and stops fortune
Turn.
5. Full-automatic chemiluminescence immunoassay analysis meter according to claim 4, which is characterized in that
The rack includes pedestal, riser and transverse slat, and the both ends of the riser are connected with the pedestal and transverse slat respectively, and position
Between the pedestal and transverse slat；The lifting device includes driving portion, driving section and sliding block, and the driving portion is arranged described
On pedestal, slide opening is provided on the riser, the output end of the driving portion passes through the slide opening and is connected with the driving section；
The sliding block is set in the bottom end of the guide rod, and is connected with the driving section, and the upper end of the guide rod passes through described
Transverse slat is connected with the rotating device, and the driving portion can drive the driving section to be driven, to drive the sliding block or more
It is mobile, so that the guide rod be made to move up and down.
6. Full-automatic chemiluminescence immunoassay analysis meter according to claim 5, which is characterized in that
The acquisition device further includes anti-collision protection device；
The anti-collision protection device includes optocoupler baffle, the second photoelectric sensor and spring；The optocoupler baffle and the acquisition
The upper end of needle is connected, and is pressed in the swing arm by the spring；Second photoelectric sensor is fixed by the bracket in institute
It states in swing arm, and is electrically connected with the driving portion, it is described to acquire the upper of needle when the lower end of the acquisition needle bumps against barrier
End jacks up the optocoupler baffle, at this point, the spring-compressed, the optocoupler baffle blocks the light of second photoelectric sensor
Coupling, second photoelectric sensor control the driving portion and stop working.
7. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1 to 6, which is characterized in that
The acquisition device is used for collecting sample and reagent.
8. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1 to 6, which is characterized in that described to adopt
Packaging is set to sample collecting device and reagent acquisition device, is respectively used to collecting sample and reagent.
9. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that
The reaction cup grabbing device includes fixing seat, driving device, cam chair, guide holder, the first calvus and the second calvus；
The driving device, guide holder are separately fixed in the fixing seat, the output of the cam chair and the driving device
Axis is connected, and cam mechanism is provided on the cam chair, and first calvus and the second calvus are set by what guide rod slided
It sets in guide holder, and is respectively arranged with the connection matched with the cam mechanism on first calvus and the second calvus
Portion；
It drives the cam chair to rotate when the rotation of the output axial direction first direction of the driving device, and then makes the cam machine
Structure drives first calvus and the second calvus to relatively move on the guide rod, to grab reaction cup；When the driving fills
It drives the cam chair to rotate when the output axial direction second direction rotation set, and then makes the first pawl described in the cam mechanism driving
Piece and the second calvus are mutually separate mobile on the guide rod, to decontrol the reaction cup.
10. Full-automatic chemiluminescence immunoassay analysis meter according to claim 9, which is characterized in that
The reaction cup grabbing device further includes detection device；
The detection device setting is on the fixing seat, described when detecting for detecting the turned position of the cam chair
When cam chair turns to predeterminated position, the detection device controls the driving device and stops.
11. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that
The magnetic separating device includes rack, waste discharge needle, cleaning needle, transport mechanism, magnet assemblies and for placing response cup
Store block；
The transport mechanism is arranged in the rack, and the storage block is connected with the transport mechanism, the transport mechanism
For the storage block to be sent to waste discharge position and cleaning position in the rack, and first is provided at the cleaning position and is mixed
Even device, the magnet assemblies are arranged at the waste discharge position, for carrying out to the magnetic bead in the reaction cup on the storage block
Magnetic suck；
The waste discharge needle and the cleaning needle are separately positioned on needle stand, and corresponding setting is in the waste discharge position and cleaning
The top of position, and the needle stand is arranged in the rack by lifting device, the lifting device drives the needle stand to rise
Drop movement；
It further include substrate needle and the second evenly mixing device；
The substrate needle is arranged in the rack by bracket, and is located at the substrate storage position of the rack；
Second evenly mixing device is arranged at the substrate storage position, and the reaction cup can be in the transmission of the transport mechanism
Effect is displaced downwardly to the substrate storage position.
12. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that
The optical detection acquisition device includes optical detecting module, acquisition module and carrier；
The installation position for accommodating reaction cup, and the carrier corresponding with the reaction cup are provided on the carrier
Side wall on be provided with light-emitting window；
The optical detecting module corresponds to the light-emitting window setting, irradiates for receiving the sample in reaction cup from the light-emitting window
Light out, and optical detection is carried out to the sample, and the optical detecting module is electrically connected with the acquisition module, it is described
The result that optical detecting module will test is sent to the acquisition module.
13. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that
The refrigerating plant includes cooling piece, temperature sensor and temperature switch, and the cooling piece setting is stored in the reagent
At the bit of storage of device, for freezing to reagent, the cooling piece respectively with the temperature sensor and temperature switch phase
Connection, and the temperature sensor is connected with the temperature switch, when the temperature sensor detects the temperature of the cooling piece
Degree reaches preset value, and the temperature switch controls the cooling piece and stops working.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821270582.5U CN208537421U (en) | 2018-08-07 | 2018-08-07 | Full-automatic chemiluminescence immunoassay analysis meter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821270582.5U CN208537421U (en) | 2018-08-07 | 2018-08-07 | Full-automatic chemiluminescence immunoassay analysis meter |
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| Publication Number | Publication Date |
|---|---|
| CN208537421U true CN208537421U (en) | 2019-02-22 |
Family
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| CN201821270582.5U Active CN208537421U (en) | 2018-08-07 | 2018-08-07 | Full-automatic chemiluminescence immunoassay analysis meter |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108732164A (en) * | 2018-08-07 | 2018-11-02 | 广州万孚生物技术股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter |
| CN112857937A (en) * | 2021-01-25 | 2021-05-28 | 吉林省吉科软信息技术有限公司 | Automatic pesticide residue detection system based on food safety |
| WO2023098391A1 (en) * | 2021-12-03 | 2023-06-08 | 中翰盛泰生物技术股份有限公司 | Reaction cup conveying device |
-
2018
- 2018-08-07 CN CN201821270582.5U patent/CN208537421U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108732164A (en) * | 2018-08-07 | 2018-11-02 | 广州万孚生物技术股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter |
| CN108732164B (en) * | 2018-08-07 | 2023-09-29 | 广州万孚生物技术股份有限公司 | Full-automatic chemiluminescence immunoassay instrument |
| CN112857937A (en) * | 2021-01-25 | 2021-05-28 | 吉林省吉科软信息技术有限公司 | Automatic pesticide residue detection system based on food safety |
| CN112857937B (en) * | 2021-01-25 | 2022-07-01 | 吉林省吉科软信息技术有限公司 | Automatic pesticide residue detection system based on food safety |
| WO2023098391A1 (en) * | 2021-12-03 | 2023-06-08 | 中翰盛泰生物技术股份有限公司 | Reaction cup conveying device |
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