CN207837917U - A kind of cellular-type cleaning system with sampled functions - Google Patents

Abstract

The utility model discloses a kind of cellular-type cleaning systems with sampled functions, are related to biological material deal device technical field.It can not adapt to produce in enormous quantities and cell free degree can not be grasped in real time to invent to solve the problems, such as that the prior art takes off cell device.The utility model has the cellular-type cleaning system of sampled functions, including shaking table, the shaking table includes swinging pallet, the swing pallet is equipped with cleaning case, the cleaning case includes multiple rinse baths, the rinse bath is for placing biomaterial and de- cell reagent, and the cleaning case is connected with sampler, and the sampler can extract the de- cell reagent in the cleaning case.There is the utility model the cellular-type cleaning system of sampled functions can be used for the de- cell of biomaterial.

Description

A kind of cellular-type cleaning system with sampled functions

Technical field

The utility model is related to biological material deal device technical field more particularly to a kind of separations with sampled functions Formula cleaning system.

Background technology

With the development of economy and society, the application of biomaterial medically also seems more and more prominent, biomaterial Refer to the process of the material formed by biology, including cell and extracellular matrix.Common biomaterial have bovine pericardium and Chitterlings need to clean biomaterial, sterilizing, take off the processing such as cell when biomaterial is applied to clinical Process.

In the prior art, generally use shaking table carries out de- cell and specifically fixes a cleaning on the pallet of shaking table Box is put into biomaterial and de- cell reagent in cleaning box, is then turned on shaking table and is vibrated, in oscillatory process, cleaning Box inner wall flops biomaterial repeatedly, to realize the de- cell of biomaterial.

But since the oscillation amplitude of shaking table limits, the volume of cleaning box can not be made big, can make if volume is too big Cleaning box two lateral walls spacing it is very big, as a result, biomaterial during cleaning box vibrates also not with cleaning box Inner wall generates slap, and just warp-wise negative direction has moved, to cannot achieve de- cell.Therefore, the de- cell cleaning of the prior art Box, in order to adapt to the oscillation amplitude of shaking table, usual volume is all smaller, can not adapt to produce in enormous quantities.Also, carrying out de- cell During, de- cell reagent can change, and the scheme of the prior art can not grasp the situation of change of de- cell reagent in real time, Also cell free degree can not be just grasped in real time, it is thereby possible to the just row of shutdown when the also not up to de- cell of biomaterial requires Liquid, or have reached the when of requiring in biomaterial and be still switched on operating, cause energy waste.

Utility model content

The embodiments of the present invention provide a kind of cellular-type cleaning system with sampled functions, can grasp in real time de- The situation of change of cell reagent, to the start and stop of accuracy-control system.

In order to achieve the above objectives, the embodiments of the present invention provide a kind of cellular-type cleaning system with sampled functions System, including shaking table, the shaking table include swinging pallet, and the swing pallet is equipped with cleaning case, and the cleaning case includes multiple Rinse bath, for the rinse bath for placing biomaterial and de- cell reagent, the cleaning case is connected with sampler, described to take Sampling device can extract the de- cell reagent in the cleaning case.

The utility model has the cellular-type cleaning system of sampled functions, since the cleaning case includes multiple rinse baths, Therefore, the volume of each rinse bath can be made as adapting to the maximum volume of shaking table oscillation amplitude, clear with one of the prior art It washes box to compare, increases the processing quantity of biomaterial.And since cleaning case is connected with sampler, the sampler can The de- cell reagent in the cleaning case is extracted, so as to detect and grasp the situation of change of de- cell reagent in real time, to The start and stop of accuracy-control system.

Description of the drawings

In order to illustrate the embodiment of the utility model or the technical proposal in the existing technology more clearly, below will be to embodiment Or attached drawing needed to be used in the description of the prior art is briefly described, it should be apparent that, the accompanying drawings in the following description is only It is some embodiments of the utility model, for those of ordinary skill in the art, in the premise not made the creative labor Under, other drawings may also be obtained based on these drawings.

Fig. 1 is the overall structure diagram of the utility model embodiment cellular-type cleaning system；

Fig. 2 is connected to the structure in outer-layer box body for the sampler of the utility model embodiment cellular-type cleaning system and shows It is intended to；

Fig. 3 is that the sampler of the utility model embodiment cellular-type cleaning system is connected to the structural representation on drain pipe Figure；

Fig. 4 is that the structure of another implementation of the sampler of the utility model embodiment cellular-type cleaning system is shown It is intended to；

Fig. 5 is the structural schematic diagram of the interior layer box body of the utility model embodiment cellular-type cleaning system；

Fig. 6 is the bottom substance schematic diagram of the interior layer box body of the utility model embodiment cellular-type cleaning system.

Specific implementation mode

The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work The every other embodiment obtained, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be understood that term "center", "upper", "lower", "front", "rear", The orientation or positional relationship of the instructions such as "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is based on attached drawing institute The orientation or positional relationship shown, is merely for convenience of describing the present invention and simplifying the description, rather than indicates or imply and is signified Device or element must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as to this practicality Novel limitation.In the description of the present invention, unless otherwise indicated, the meaning of " plurality " is two or more.

Referring to Fig.1, Fig. 2, the cellular-type cleaning system with sampled functions of the present embodiment, including shaking table 3, the shaking table 3 include swinging pallet, and the swing pallet is equipped with cleaning case, and the cleaning case includes multiple rinse baths 21, the rinse bath 21 for placing biomaterial and de- cell reagent, and the cleaning case is connected with sampler 4, and the sampler 4 can extract De- cell reagent in the cleaning case.

The cellular-type cleaning system with sampled functions that the utility model embodiment provides, since the cleaning case includes Multiple rinse baths 21, therefore, the volume of each rinse bath 21 can be made as adapting to the maximum volume of 3 oscillation amplitude of shaking table, with One cleaning box of the prior art is compared, and the processing quantity of biomaterial is increased.And since cleaning case is connected with sampling dress 4 are set, the sampler 4 can extract the de- cell reagent in the cleaning case, so as to detect in real time and grasp de- cell The situation of change of reagent, to the start and stop of accuracy-control system.

For the ease of drain, as shown in Fig. 2, Fig. 5, Fig. 6, the cleaning case includes outer-layer box body 1 and is set to described outer Interior layer box body 2 in layer box body 1, the interior layer box body 2 can be with 1 synchronized oscillation of outer-layer box body, the outer-layer box body 1 and the pendulum Dynamic pallet connection, the interior layer box body 2 is interior to be equipped with partition board 25, and the space in the interior layer box body 2 is divided by the partition board 25 Multiple rinse baths 21, the outer-layer box body 1 are connected with drain pipe 11, the bottom of the drain pipe 11 and the outer-layer box body 1 Portion space is connected to, and each rinse bath 21 is equipped with drainage hole 211, the bottom of the drainage hole 211 and the outer-layer box body 1 Space is connected to, the drainage hole 211 allow de- cell reagent by and do not allow biomaterial to pass through.As a result, in drain, only Drain pipe 11 need to be opened, the de- cell reagent in rinse bath 21 can be discharged by drain pipe 11, without dismantling outer-layer box body 1 and interior Layer box body 2, easy to operate, production efficiency is high.

Wherein, the arrangement mode of multiple rinse baths 21 can there are many, such as can be along same linear array at one Row, can also be by multiple rinse baths 21 along rectangular array.It is whole by the rinse bath of rectangular array compared to along linear array More compact structure, when oscillation, are not easy deformation.For example, as shown in Figure 1, the partition board 25 divides the space in the interior layer box body 2 16 rinse baths are divided into, 16 rinse bath arrays arrange for 4 rows 4.Equally, partition board 25 can also be by the sky in interior layer box body 2 Between be divided into 9 rinse baths, 9 rinse bath arrays are 3 rows 3 row.Specifically how to divide and arrange can be according to actual conditions It is selected, is not limited herein.

Wherein, the installation position of sampler 4 can be there are many mode, for example, as shown in Figure 2 and Figure 4, can be described Sample tap is opened up in outer-layer box body 1, the sampler 4 is set at the sample tap.

It, as a result, need not be in addition, as shown in figure 3, the sampler 4 is also connected on the drain pipe 11 Extra openings in outer-layer box body 1 save technique and avoid leakage hidden danger.Since drain pipe 11 needs setting tapping valve to control Its opening and closing is made, therefore, sampler 4 is preferably disposed between the tapping valve and the outer-layer box body 1, as a result, may be used It is sampled in the case where not opening valve.Avoid reagent waste.

Specifically, the structure of sampler 4 can there are many, for example, as shown in Figure 2 and Figure 3, sampler 4 can make For the structure of syringe-like, including sampling needle tubing 41 and it is equipped in the piston rod 42 in the sampling needle tubing 41.Sampling The suction side of needle tubing 41 is stretched into outer-layer box body 1 or is connected on drain pipe 11, when needing sampling, pulls piston rod 42 Extract reagent.

In another embodiment of the utility model, as shown in figure 4, the sampler 4 includes pipette 43, it is described One end of pipette 43 is for drawing de- cell reagent, and the other end is connected with sampling container 44, and the pipette 43 is connected with pumping Sucking pump 45.It is sampling to open suction pump 45 as a result, saves manpower.

Wherein, in order to realize synchronized oscillation of the interior layer box body 2 with outer-layer box body 1, can by the inside dimension of outer-layer box body 1 and The external dimensions of interior layer box body 2 matches, i.e., when interior layer box body 2 is installed in outer-layer box body 1, the madial wall of outer-layer box body 1 It is bonded to each other between the lateral wall of interior layer box body 2, so that outer-layer box body 1, during oscillation, interior layer box body 2 can not It is moved relative to outer-layer box body 1, avoids generating shock between outer-layer box body 1 and interior layer box body 2.Alternatively, it is also possible in outer layer case Location structure is set between body 1 and interior layer box body 2, prevents interior layer box body 2 from being moved relative to outer-layer box body 1 by location structure, Such as can rubber pad be set between outer-layer box body 1 and interior layer box body 2, outer-layer box body 1 is fixed in one end of rubber pad On madial wall, one end of rubber pad against or being fixed on the outside of interior layer box body 2 by the lateral wall of the other end and interior layer box body 2 On wall, the madial wall of the other end and outer-layer box body 1 against.Interior layer box body 2 equally may be implemented to shake with synchronizing for outer-layer box body 1 It swings.

As shown in figure 5, the upper surface both sides of interior layer box body 2 are equipped with handle 22, to facilitate interior layer box body 2 by outer layer case It takes out in body 1, carries out disinfection sterilization and cleaning treatment convenient for internal layer box body 2.

Specifically, structure as shown in Figure 5 and Figure 6 may be used in interior layer box body 2, i.e., including bottom plate 23 and around the bottom The side plate 24 of plate setting in 23 1 weeks, the interior layer box body 2 is interior to be equipped with partition board 25, and the partition board 25 will be in the interior layer box body 2 Space is divided into multiple rinse baths 21.Alternatively, it is also possible to not use partition board 25, directly placed in interior layer box body 2 multiple Independent rinse bath 21,21 lateral wall of multiple rinse baths is bonded each other to be closely arranged in interior layer box body 2.Scheme shown in fig. 5 It is simple in structure and low therefore relatively more economical and practical to making required precision.

In order to facilitate liquid feeding, as shown in figure 5, it is preferred that open up intercommunicating pore 251 in the lower end of partition board 25, it is two neighboring described clear Washing trough 21 is connected to by the intercommunicating pore 251.As a result, when de- cell reagent is added, need not one by one it add into rinse bath 21 Enter, need to be only added to a rinse bath 21 and take off cell reagent, so that de- cell reagent is passed through intercommunicating pore 251 and flow into other rinse baths 21 .And this scheme may make de- cell reagent dosage in each rinse bath 21 and concentration to be equal, and ensure clear with a batch The de- cell effect for the biomaterial washed is consistent.

As shown in figure 5, being arranged for one week around rinse bath 21 of intercommunicating pore 251, and vertically it is provided with two rows.Connection Hole 251 should not open up excessively, and 1~3 row is preferably vertically arranged, if setting can excessively reduce partition board 25 to liquid Flop power so that liquid drives the movement velocity of biomaterial to reduce, to reduce the bat between biomaterial and partition board 25 Power is hit, de- cell effect can be influenced.

Wherein, the set-up mode of drainage hole 211 can there are many selections, in a kind of embodiment of the utility model, such as Shown in Fig. 6, drainage hole 211 is distributed on the bottom plate 23 of interior layer box body 2, and is corresponded to respectively at multiple rinse baths 21, interior layer box body 2 Bottom plate 23 and the bottom plate 12 of the outer-layer box body 1 between be formed with and be connected to chamber 28, it is more on the bottom plate 23 of the interior layer box body 2 A drainage hole 211 is connected to the chamber 28 that is connected to.As a result, in drain, after opening drain pipe 11, in rinse bath 21 Liquid is discharged by connection chamber 28 and drain pipe 11 successively, easy to operate, need not dismantle interior layer box body 2.

In the above-described embodiments, connection chamber 28 can there are many implementations, for example, as shown in Fig. 2, can be in internal layer case Support element 27 is set between the bottom plate 23 of body 2 and the bottom plate 12 of outer-layer box body 1, by support element 27 by the bottom plate of interior layer box body 2 23 separate with the bottom plate 12 of outer-layer box body 1, make to be formed between the bottom plate 23 of interior layer box body 2 and the bottom plate 12 of outer-layer box body 1 and are connected to Chamber 28.Equally, can also hanging structure be set between the side wall and the side wall of outer-layer box body 1 of interior layer box body 2, makes interior layer box body 2 are vacantly mounted in outer-layer box body 1, and formation between the bottom plate 23 of interior layer box body 2 and the bottom plate 12 of outer-layer box body 1 is made to be connected to chamber 28。

In another embodiment of the utility model, drainage hole 211 can also be distributed in the side plate 24 of interior layer box body 2 On, as shown in Figure 5, Figure 6, drainage hole 211 is opened in the lower end of the side plate 24.As a result, in drain, drain pipe 11 is opened Afterwards, the liquid in the rinse bath at middle part 21 first passes through intercommunicating pore 251 and flows into outermost rinse bath 21, then passes through side The drainage hole 211 of 24 lower end of plate is discharged into outer-layer box body 1, is finally discharged by drain pipe 11, this scheme is again without in dismounting Layer box body 2.

It should be noted that the plan of establishment of above two drainage hole 211 can only with one kind, can also two kinds simultaneously Using.When only with the first scheme, when beginning to rehearse fluid apertures 211 on the bottom plate 23 of interior layer box body 2, drainage hole 211 is easy to be given birth to Object material blocks, and drain is ineffective, therefore preferably two schemes use simultaneously.

Wherein, the diameter of drainage hole 211 preferably uses 3 millimeters, is easy to be caught in biomaterial if aperture is too big, if aperture Too small then drain age velocity is too slow.

Wherein, the horizontal cross-section of rinse bath 21 can be rectangle, square, polygon circle etc., not limit herein. Since the oscillation amplitude of general common shaking table 3 is 30~60 millimeters, in order to ensure that rinse bath 21 can adapt to the oscillation of shaking table 3 The full-size of the rinse bath 21 in the horizontal direction is preferably set smaller than or equal to 300 millimeters by amplitude.For example, cleaning When slot 21 is rectangle, the width of rinse bath 21 can be set to 140 millimeters, length is set as 230 millimeters.

Preferably, the height of the rinse bath 21 vertically should be greater than or be equal to 100 millimeters, such as height may be selected It is 250 millimeters, thus can prevents the liquid in rinse bath 21 from being splashed out in oscillation.

It is discharged, the bottom plate 12 of the outer-layer box body 1 can be obliquely installed for the ease of liquid, and the outer-layer box body 1 The minimum point of bottom plate 12 is arranged close to the drain pipe 11.It may make the de- cell reagent in outer-layer box body 1 along inclined-plane stream as a result, It moves to 11 inlet of drain pipe, takes off cell reagent to prevent the bottom of outer-layer box body 1 from remaining.

In 3 oscillatory process of shaking table, biomaterial is easy to be got rid of to the opening of interior layer box body 2, and rides on partition board 25 Edge, so that the biomaterial can not complete de- cell, in order to avoid the above problem, as shown in Fig. 2, it is preferred that in internal layer case The opening setting internal layer case lid 26 of body 2, and set the internal layer case lid 26 to plate-like structure, the side plate 24 and described In the upper edge of partition board 25 is generally aligned in the same plane, the internal layer case lid 26 is covered on the side plate 24 and the partition board 25.By This, internal layer case lid 26 and the upper edge of side plate 24 and the partition board 25 fit closely so that biomaterial can not ride over partition board 25 Or 24 upper edge of side plate.

In addition, as shown in Figure 1, outer layer case lid 13 can also be arranged in the opening of outer-layer box body 1, to prevent the external world miscellaneous Matter, which enters, to be taken off in cell reagent, and biomaterial is polluted.

Preferably, the outer-layer box body 1 for taking off cell net cage is fixed on by clamping structure on swing pallet, such as Fig. 1 institutes Show, the bottom surface of shaking table 3 is equipped with retractable idler wheel 31, facilitates the carrying of shaking table 3.

Above description is only a specific implementation of the present invention, but the scope of protection of the utility model is not limited to In this, any one skilled in the art within the technical scope disclosed by the utility model, can readily occur in variation Or replace, it should be covered within the scope of the utility model.Therefore, the scope of protection of the utility model should be with the power Subject to the protection domain that profit requires.

Claims (10)

1. a kind of cellular-type cleaning system with sampled functions, which is characterized in that including shaking table, the shaking table includes swinging to hold in the palm Disk, the swing pallet are equipped with cleaning case, and the cleaning case includes multiple rinse baths, and the rinse bath is for placing biological material Material and de- cell reagent, the cleaning case are connected with sampler, and the sampler can extract de- thin in the cleaning case Born of the same parents' reagent.

2. the cellular-type cleaning system according to claim 1 with sampled functions, which is characterized in that the cleaning luggage The interior layer box body for including outer-layer box body and being set in the outer-layer box body, the interior layer box body can with outer-layer box body synchronized oscillation, The outer-layer box body is connect with the shaking table, partition board is equipped in the interior layer box body, the partition board will be in the interior layer box body Space is divided into multiple rinse baths, and the outer-layer box body is connected with drain pipe, the drain pipe and the outer-layer box body Bottom space is connected to, and each rinse bath is equipped with drainage hole, and the drainage hole and the bottom space of the outer-layer box body connect It is logical, the drainage hole allow de- cell reagent by and do not allow biomaterial to pass through.

3. the cellular-type cleaning system according to claim 2 with sampled functions, which is characterized in that the outer-layer box body Sample tap is offered, the sampler is set at the sample tap.

4. the cellular-type cleaning system according to claim 2 with sampled functions, which is characterized in that the drain pipe string Be connected to tapping valve, the sampler is connect with the drain pipe, and the sampler be set to the tapping valve with it is described Between outer-layer box body.

5. the cellular-type cleaning system according to any one of claims 1 to 4 with sampled functions, which is characterized in that The sampler includes sampling needle tubing and being equipped in the piston rod in the sampling needle tubing.

6. the cellular-type cleaning system according to any one of claims 1 to 4 with sampled functions, which is characterized in that The sampler includes pipette, and for drawing de- cell reagent, the other end, which is connected with sampling, to be held for one end of the pipette Device, the pipette are connected with suction pump.

7. the cellular-type cleaning system with sampled functions according to any one of claim 2~4, which is characterized in that The interior layer box body includes bottom plate and the side plate around bottom plate setting in one week, and the partition board is set on the bottom plate, the row Fluid apertures is multiple, and at least part drainage hole is opened on the bottom plate of the interior layer box body, the bottom plate of the interior layer box body It is formed between the bottom plate of the outer-layer box body and is connected to chamber, multiple drainage holes on the bottom plate of the interior layer box body pass through The connection chamber connection.

8. the cellular-type cleaning system according to claim 7 with sampled functions, which is characterized in that under the partition board End offers intercommunicating pore, and the two neighboring rinse bath is connected to by the intercommunicating pore.

9. the cellular-type cleaning system according to claim 8 with sampled functions, which is characterized in that at least part institute State the lower end that drainage hole is opened in the side plate.

10. the cellular-type cleaning system with sampled functions according to any one of claim 2~4, which is characterized in that The bottom plate of the outer-layer box body is obliquely installed, and the minimum point of the bottom plate of the outer-layer box body is arranged close to the drain pipe.