CN207655117U - A kind of concentration kettle for producing sildenafil intermediate - Google Patents

A kind of concentration kettle for producing sildenafil intermediate Download PDF

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Publication number
CN207655117U
CN207655117U CN201721364150.6U CN201721364150U CN207655117U CN 207655117 U CN207655117 U CN 207655117U CN 201721364150 U CN201721364150 U CN 201721364150U CN 207655117 U CN207655117 U CN 207655117U
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China
Prior art keywords
concentration kettle
compression
fixedly connected
agitator tank
agitating device
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Expired - Fee Related
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CN201721364150.6U
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Chinese (zh)
Inventor
阮海林
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Anhui Sheng Kang Pharmaceutical Co Ltd
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Anhui Sheng Kang Pharmaceutical Co Ltd
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Priority to CN201721364150.6U priority Critical patent/CN207655117U/en
Application granted granted Critical
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Expired - Fee Related legal-status Critical Current
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Abstract

The utility model discloses a kind of concentration kettles for producing sildenafil intermediate, are related to medical pharmaceutical technology field.This is used to produce the concentration kettle of sildenafil intermediate, including concentration kettle ontology, the concentration kettle ontology include agitating device and compression set, are fixedly linked at the top of the bottom of the agitating device and compression set.This is used to produce the concentration kettle of sildenafil intermediate, stirring lower box part designs for incline structure, on the one hand, concentration kettle ontology improves the sinking speed of material by agitating device, on the other hand, concentration kettle ontology carries out Fast Compression by the compression set material stirred to agitating device, the working efficiency of concentration kettle ontology can be promoted, novel in structural design, it is rationally distributed, conducive to promoting the use of, solves the existing concentration kettle for producing sildenafil intermediate, material sinking speed is slower, working efficiency is relatively low, the problem of being unfavorable for promoting the use of.

Description

A kind of concentration kettle for producing sildenafil intermediate
Technical field
The utility model is related to medical pharmaceutical technology fields, specially a kind of for producing among sildenafil The concentration kettle of body.
Background technology
The broad understanding of reaction kettle has the container physically or chemically reacted, is matched with parameter by the structure design to container It sets, realizes the mixture function of the heating of technological requirement, evaporation, cooling and low high speed.Reaction kettle be widely used in oil, chemical industry, Rubber, pesticide, dyestuff, medicine, food, for completing the pressure of the technical process such as vulcanization, nitrification, hydrogenation, hydrocarbonylation, polymerization, condensation Force container, such as reactor, reaction pot, decomposition pot, polymeric kettle etc.;Material generally has carbon manganese steel, stainless steel, zirconium, Ni-based (Kazakhstan Family name, Monel, inconel) alloy and other composite materials.The broad understanding of reaction kettle, which has, physically or chemically reacts stainless Steel container carries out the structure design and parameter configuration of container, design condition, process, inspection according to different process conditions demands And manufacture, check and accept and need according to Its Relevant Technology Standards, the mixture to realize the heating of technological requirement, evaporation, cooling and low high speed is anti- Answer function.Pressure vessel must comply with the standard of GB150 { steel pressure vessel }, and non-pressure vessel must comply with NB/T47003.1- The standard of 2009 { steel welding non-pressure vessels }.The pressure requirements in reaction process are to the design requirement of container also phase not to the utmost therewith Together.Production must be processed, be detected in strict accordance with corresponding standard and trial operation.Stainless steel cauldron is according to different production works Skill, operating condition etc. are not quite similar, and the design structure and parameter of reaction kettle are different, i.e. the structural style of reaction kettle is different, belongs to Nonstandard tankage.
Reaction kettle is comprehensive reaction vessel, the design according to reaction condition to reaction kettle structure function and configuration attachment.From Charging-reaction-discharging of beginning can complete pre-set reaction step with higher the degree of automation, to reacting The important parameters such as temperature, pressure, mechanics control (stirring, air blast etc.), reactant/product concentration in journey carry out stringent tune Control.Its structure is generally made of autoclave body, transmission device, agitating device, heating device, cooling device, sealing device.It is corresponding mating Ancillary equipment:Still, condenser, water knockout drum, collecting tank, filter etc..
Reaction kettle material generally has carbon manganese steel, stainless steel, zirconium, Ni-based (Kazakhstan, Monel) alloy and other composite materials. The manufacture of the stainless steel materials such as SUS304, SUS316L can be used in reaction kettle.Blender has anchor formula, frame, paddle, turbine type, scraper plate Cycloidal planetary gear speed reducer, stepless reducer or frequency control etc. can be used in formula, combined type, rotating mechanism, can meet various The special reaction requirement of material.The sealing structures such as mechanical seal, packing seal can be used in sealing device.Heating, cooling can be used Structures, the mode of heatings such as chuck, semicanal, coil pipe, Miller plate have:Steam, electrical heating, conduction oil, with meet acidproof, high temperature resistant, The technique of the different operatings environment such as wear-resistant, anticorrosive needs.And it can be designed, be manufactured according to user's technological requirement.
Sildenafil citrate is drug name, main component and chemical name:1- [4- ethyoxyls -3- [5- (6,7- dihydros - 1- methyl -7- oxos -3- propyl -1H- pyrazolos [4,3d] pyrimidine)] benzene sulfonyl] -4- methylpiperazine citrate this product be indigo plant Color diamond shape film-coating, remove film-coating after be white pulvis.
Currently, the existing concentration kettle for producing sildenafil intermediate, material sinking speed is slower, work Make less efficient, is unfavorable for promoting the use of.
Utility model content
(1) the technical issues of solving
In view of the deficiencies of the prior art, the utility model provides a kind of for producing sildenafil intermediate Concentration kettle, solve it is existing for producing the concentration kettle of sildenafil intermediate, sinking speed is slower, work It is less efficient, the problem of being unfavorable for promoting the use of.
(2) technical solution
In order to achieve the above object, the utility model is achieved by the following technical programs:One kind for produce western ground that The concentration kettle of non-citrate intermediate, including concentration kettle ontology, the concentration kettle ontology include agitating device and compression set, It is fixedly linked at the top of the bottom of the agitating device and compression set, the agitating device includes agitator tank, the agitator tank Top be fixedly connected with stirring motor, the first feeding mouth, the one side of the agitator tank are additionally provided at the top of the agitator tank Equipped with the second feeding mouth, the compression set includes compression box, and the one side of the compression box is fixedly connected with telescope motor, institute The telescopic shaft for stating telescope motor extends to the inside of compression box, the discharge port and the entrance at the top of compression box of the agitator tank bottom Place is connected, and the discharge port of the agitator tank bottom is equipped with electromagnetic valve, and the compression box is internally provided with compression blocks, The outer surface of compression blocks is fixedly connected with sealant, which is high-molecular polythene wear-resistant sealant, the compression blocks The telescopic shaft of one side and telescope motor is fixedly linked, and the one side of the compression box far from telescope motor is fixedly connected with filtering Plate offers on the filter plate and is uniformly distributed filter mesh, and the side of the filter plate is exported equipped with material leakage, and the material leakage goes out Mouth is fixedly connected in compression box.
Preferably, the agitator tank is internally provided with agitating shaft, and the top of the agitating shaft passes through shaft coupling and stirring electricity The output shaft of machine is fixedly linked, and the outer surface of the agitating shaft is fixedly connected with stirring blade.
Preferably, the bottom of the compression box is fixedly connected with support leg, and the bottom of the support leg is fixedly connected with bottom Plate.
Preferably, rewinding case is fixedly connected on the bottom plate, the rewinding case is located at the underface of material leakage outlet.
Preferably, the bottom of the telescope motor is fixedly connected with transverse slat, and one end of the transverse slat is fixedly connected on compression On case.
(3) advantageous effect
The utility model provides a kind of for producing the concentration kettle of sildenafil intermediate, and having following has Beneficial effect:
(1) concentration kettle for being used to produce sildenafil intermediate, stirring lower box part design for incline structure, On the one hand, concentration kettle ontology improves the sinking speed of material by agitating device, and on the other hand, concentration kettle ontology passes through compression The device material stirred to agitating device carries out Fast Compression, can promote the working efficiency of concentration kettle ontology, structure design Novelty, it is rationally distributed, conducive to promoting the use of, solve the existing concentration for producing sildenafil intermediate Kettle, material sinking speed is slower, and working efficiency is relatively low, the problem of being unfavorable for promoting the use of.
(2) concentration kettle for being used to produce sildenafil intermediate, on the one hand, the outer surface of compression blocks is fixed It is connected with sealant, on the other hand, which is high-molecular polythene wear-resistant sealant, can promote compression blocks and compression box Between leakproofness, and then promoted compression set reduced overall effect, novel in structural design is rationally distributed, makes conducive to popularization With.
Description of the drawings
FIG. 1 is a schematic structural view of the utility model;
Fig. 2 is the structural schematic diagram of the utility model agitating device
Fig. 3 is the structural schematic diagram of the utility model compression set part.
In figure:1 concentration kettle ontology, 2 agitating devices, 201 agitator tanks, 202 stirring motors, 203 first feeding mouths, 204 Two feeding mouths, 205 electromagnetic valves, 206 agitating shafts, 207 stirring blades, 3 compression sets, 301 compression box, 302 telescope motors, 303 telescopic shafts, 304 compression blocks, 3041 sealants, 305 filter plates, the outlet of 306 material leakages, 307 support legs, 308 bottom plates, 4 rewindings Case, 5 transverse slats.
Specific implementation mode
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.
Examples of the embodiments are shown in the accompanying drawings, and in which the same or similar labels are throughly indicated identical or classes As element or element with the same or similar functions.The embodiments described below with reference to the accompanying drawings are exemplary, purport For explaining the utility model, and should not be understood as limiting the present invention.
In the description of the present invention, it should be understood that term "center", " longitudinal direction ", " transverse direction ", " length ", " width Degree ", " thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", "outside", " suitable The orientation or positional relationship of the instructions such as hour hands ", " counterclockwise ", " axial direction ", " radial direction ", " circumferential direction " is orientation based on ... shown in the drawings Or position relationship, be merely for convenience of describing the present invention and simplifying the description, do not indicate or imply the indicated device or Element must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as the limit to the utility model System.
In addition, term " first ", " second " are used for description purposes only, it is not understood to indicate or imply relative importance Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Implicitly include one or more this feature.The meaning of " plurality " is two or two in the description of the present invention, More than, unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " Gu It is fixed " etc. terms shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral;Can be Mechanical connection can also be electrical connection;It can be directly connected, can also can be indirectly connected through an intermediary two The interaction relationship of connection or two elements inside element.It for the ordinary skill in the art, can basis Concrete condition understands the concrete meaning of above-mentioned term in the present invention.
- 3 are please referred to Fig.1, the utility model provides a kind of technical solution:One kind is for producing in sildenafil The concentration kettle of mesosome, including concentration kettle ontology 1, concentration kettle ontology 1 include agitating device 2 and compression set 3, agitating device 2 Bottom and the top of compression set 3 are fixedly linked, and agitating device 2 includes agitator tank 201, and the top of agitator tank 201 is fixedly connected There are stirring motor 202, the top of agitator tank 201 to be additionally provided with the first feeding mouth 203, the one side of agitator tank 201 enters equipped with second Material mouth 204, agitator tank 201 are internally provided with agitating shaft 206, and the top of agitating shaft 206 passes through shaft coupling and stirring motor 202 Output shaft is fixedly linked, and the outer surface of agitating shaft 206 is fixedly connected with stirring blade 207, and compression set 3 includes compression box 301, The one side of compression box 301 is fixedly connected with telescope motor 302, and the bottom of telescope motor 302 is fixedly connected with transverse slat 5, transverse slat 5 One end be fixedly connected in compression box 301, the telescopic shaft 303 of telescope motor 302 extends to the inside of compression box 301, stirring The discharge port of 201 bottom of case is connected with the inlet at 301 top of compression box, and the discharge port of 201 bottom of agitator tank is equipped with Electromagnetic valve 205, compression box 301 are internally provided with compression blocks 304, the outer surface of compression blocks 304 is fixedly connected with sealant 3041, which is high-molecular polythene wear-resistant sealant, the one side of compression blocks 304 and stretching for telescope motor 302 Contracting axis 303 is fixedly linked, and one side of the compression box 301 far from telescope motor 302 is fixedly connected with filter plate 305, filter plate 305 On offer and be uniformly distributed filter mesh, the side of filter plate 305 is equipped with material leakage and exports 306, and material leakage outlet 306 is fixedly connected on In compression box 301, the bottom of compression box 301 is fixedly connected with support leg 307, and the bottom of support leg 307 is fixedly connected with bottom plate 308, rewinding case 4 is fixedly connected on bottom plate 308, rewinding case 4 is located at the underface of material leakage outlet 306.
The electric elements occurred in this article are electrically connected with extraneous main controller and 220V alternating currents, and main controller can be meter Calculation machine etc. plays the conventionally known equipment of control.
In conclusion this is used to produce the concentration kettle of sildenafil intermediate, 201 lower part of agitator tank is to tilt Structure design, on the one hand, concentration kettle ontology 1 improves the sinking speed of material by agitating device 2, on the other hand, concentration kettle Ontology 1 carries out Fast Compression by the material stirred to agitating device 2 of compression set 3, can promote the work of concentration kettle ontology 1 Make efficiency, novel in structural design is rationally distributed, conducive to promoting the use of, solves existing for producing silaenafil citric acid The concentration kettle of salt intermediate, material sinking speed is slower, and working efficiency is relatively low, the problem of being unfavorable for promoting the use of.
And, on the one hand, the outer surface of compression blocks 304 is fixedly connected with sealant 3041, on the other hand, the sealant 3041 be high-molecular polythene wear-resistant sealant, can promote the leakproofness between compression blocks 304 and compression box 301, Jin Erti The reduced overall effect of boosting compression apparatus 3, novel in structural design is rationally distributed, conducive to promoting the use of.
It should be noted that in the present invention unless specifically defined or limited otherwise, fisrt feature is in the second spy Can be that the first and second features are in direct contact or the first and second features are connect indirectly by intermediary "above" or "below" sign It touches.Moreover, fisrt feature second feature " on ", " top " and " above " but fisrt feature right over second feature or Oblique upper, or be merely representative of fisrt feature level height and be higher than second feature.Fisrt feature second feature " under ", " lower section " " following " can be that fisrt feature is directly under or diagonally below the second feature, or is merely representative of fisrt feature level height and is less than Second feature.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example Point is contained at least one embodiment or example of the utility model.In the present specification, to the schematic table of above-mentioned term It states and may not refer to the same embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be It can be combined in any suitable manner in any one or more embodiments or example.
The preferable specific implementation mode of the above, only the utility model, but the scope of protection of the utility model is not Be confined to this, any one skilled in the art within the technical scope disclosed by the utility model, according to this practicality Novel technical solution and its utility model design are subject to equivalent substitution or change, should all cover the protection model in the utility model Within enclosing.

Claims (5)

1. a kind of concentration kettle for producing sildenafil intermediate, including concentration kettle ontology (1), feature exists In:The concentration kettle ontology (1) includes agitating device (2) and compression set (3), the bottom of the agitating device (2) and compression Device is fixedly linked at the top of (3), and the agitating device (2) includes agitator tank (201), and the top of the agitator tank (201) is solid Surely it is connected with stirring motor (202), the first feeding mouth (203), the agitator tank are additionally provided at the top of the agitator tank (201) (201) one side is equipped with the second feeding mouth (204), and the compression set (3) includes compression box (301), the compression box (301) one side is fixedly connected with telescope motor (302), and the telescopic shaft (303) of the telescope motor (302) extends to compression The discharge port of the inside of case (301), agitator tank (201) bottom is connected with the inlet at the top of compression box (301), and institute The discharge port for stating agitator tank (201) bottom is equipped with electromagnetic valve (205), and the compression box (301) is internally provided with compression blocks (304), the outer surface of compression blocks (304) is fixedly connected with sealant (3041), which is high molecular polythene Abrasion sealer, the one side of the compression blocks (304) are fixedly linked with the telescopic shaft (303) of telescope motor (302), the pressure One side of the contracting case (301) far from telescope motor (302) is fixedly connected with filter plate (305), is opened up on the filter plate (305) It is uniformly distributed filter mesh, the side of the filter plate (305) is equipped with material leakage and exports (306), and the material leakage outlet (306) is solid Surely it is connected in compression box (301).
2. a kind of concentration kettle for producing sildenafil intermediate according to claim 1, feature exist In:The agitator tank (201) is internally provided with agitating shaft (206), and the top of the agitating shaft (206) passes through shaft coupling and stirring The output shaft of motor (202) is fixedly linked, and the outer surface of the agitating shaft (206) is fixedly connected with stirring blade (207).
3. a kind of concentration kettle for producing sildenafil intermediate according to claim 1, feature exist In:The bottom of the compression box (301) is fixedly connected with support leg (307), and the bottom of the support leg (307) is fixedly connected with Bottom plate (308).
4. a kind of concentration kettle for producing sildenafil intermediate according to claim 3, feature exist In:Rewinding case (4) is fixedly connected on the bottom plate (308), the rewinding case (4) is located at the underface of material leakage outlet (306).
5. a kind of concentration kettle for producing sildenafil intermediate according to claim 1, feature exist In:The bottom of the telescope motor (302) is fixedly connected with transverse slat (5), and one end of the transverse slat (5) is fixedly connected on compression box (301) on.
CN201721364150.6U 2017-10-23 2017-10-23 A kind of concentration kettle for producing sildenafil intermediate Expired - Fee Related CN207655117U (en)

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CN201721364150.6U CN207655117U (en) 2017-10-23 2017-10-23 A kind of concentration kettle for producing sildenafil intermediate

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Application Number Priority Date Filing Date Title
CN201721364150.6U CN207655117U (en) 2017-10-23 2017-10-23 A kind of concentration kettle for producing sildenafil intermediate

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109453731A (en) * 2018-11-23 2019-03-12 南京森尔电力器材有限公司 A kind of production of environment-friendly type plastic material stabilizer and transmitting device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109453731A (en) * 2018-11-23 2019-03-12 南京森尔电力器材有限公司 A kind of production of environment-friendly type plastic material stabilizer and transmitting device
CN109453731B (en) * 2018-11-23 2020-11-24 南京森尔电力器材有限公司 Production and transmission device of environmental protection type plastic stabilizer

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20180727

Termination date: 20201023