CN207457480U - High contrast low dosage phase contrast CT image-forming device - Google Patents
High contrast low dosage phase contrast CT image-forming device Download PDFInfo
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- CN207457480U CN207457480U CN201721367057.0U CN201721367057U CN207457480U CN 207457480 U CN207457480 U CN 207457480U CN 201721367057 U CN201721367057 U CN 201721367057U CN 207457480 U CN207457480 U CN 207457480U
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Abstract
The utility model discloses a kind of high contrast low dosage phase contrast CT image-forming device, including：Pedestal, turntable, imaging platform and the sample stage for being arranged on turntable inside circle centre position embedded vertically；X-ray source is disposed with along optical path direction, source grating, beam-splitting optical grating, the top for the sample stage are stretched the perforate being pierced by, analysis grating and detector in the imaging platform；Source grating, beam-splitting optical grating and the analysis grating is arc shape, and the center of circle is respectively positioned at the X-ray source.The high contrast low dosage phase contrast CT image-forming device of the utility model can utilize the X source of high-energy to realize larger penetration depth, so as to high contrast, the low dose imaging applied to thick sample (tens centimetres) or even human body.And the imaging device of the utility model can realize sample stage rotation and realize that imaging system rotates, reliable and stable, be capable of providing the required required precision of the imaging technique.
Description
Technical field
The utility model is related to X-ray technical field of imaging, more particularly to a kind of high contrast low dosage phase contrast CT image-forming
Device.
Background technology
Traditional x-ray imaging technique is the difference to X-ray absorption property based on substance, for heavy element materials such as metals
The substance of composition, Traditional x-ray imaging technique can obtain good image contrast, but for the light member such as carbon, oxygen, nitrogen, oxygen
The substance of cellulosic material composition, such as mammary gland, blood vessel, fat, cartilage human body soft tissue in medical imaging, they are to X-ray
Absorb it is very faint, these be organized in the image obtained under Traditional x-ray imaging technique be blur, differentiate it is unclear.
X-ray phase contrast imaging technology is carried out by detecting X-ray through the phase place change (i.e. phase shift) of substance
As due at hard X ray wave band (10-100keV), for the light elements such as carbon, hydrogen, nitrogen, oxygen, coherent scattering cross section (i.e. phase
Move section) it is more than 1000 times of respective absorption cross-section.Therefore theoretically for, for the substance that those are made of light element, hard X
Ray phase contrast imaging technology is capable of providing thousands of times higher than conventional suction contrast imaging of image contrast and measurement sensitivity.
However, for the imaging energy of the technology mainly in 30keV or so, the penetration depth in manikin only has 5 at present
Centimetre, therefore be only suitable for carrying out thin sample (such as mouse) imaging research, and it is low because of the photon flux that X-ray machine is sent, it needs
Time for exposure of when small (about 26) for a long time noise is reduced, increase picture quality.In addition, based on current theoretical frame
In the phase contrast CT machines of structure, it is necessary to which three blocks of gratings surround rotary sample together, simultaneously when framework is rotated
It needs to ensure that three blocks of gratings are strictly aligned, but in rotary course, gravity, machine-building error, Automatic manual transmission error, machinery
The factors such as vibrations, thermal expansion can all seriously affect the alignment of three blocks of gratings.Therefore, their system has very mechanical stability
Harsh requirement, it is most of both at home and abroad at present to establish sample stage rotation and the motionless simple desktop of imaging system stationary is put down
Platform, there are no the CT devices for imaging system rotation occur to come into operation.
Utility model content
The technical problem to be solved by the utility model is to the deficiencies in for the above-mentioned prior art, provide a kind of high lining
Spend low dosage phase contrast CT image-forming device.
In order to solve the above technical problems, the technical solution adopted in the utility model is：A kind of high contrast low dosage phase contrast
CT imaging devices are spent, including：Pedestal, the turntable being arranged above the pedestal, the imaging being arranged on the turntable are put down
Platform and the vertically embedded sample stage for being arranged on circle centre position inside the turntable；
In the imaging platform along optical path direction be disposed with X-ray source, source grating, beam-splitting optical grating, for the sample
The top of sample platform is stretched the perforate being pierced by, analysis grating and detector；
The beam-splitting optical grating lower end is provided with micro-displacement stepping mechanism, and the micro-displacement stepping mechanism includes flexible hinge machine
Structure and piezoelectric ceramics pushing mechanism；
The source grating and beam-splitting optical grating lower end are both provided with attitude-adjusting system；
Source grating, beam-splitting optical grating and the analysis grating is arc shape, and the center of circle is respectively positioned on the X-ray source
Place.
Preferably, it is additionally provided with to adjust the diaphragm mechanism of X-ray incidence range in the source grating.Preferably
It is to be provided with heat-proof device between the X-ray source and source grating.
Preferably, the sample stage includes elevating mechanism, planar adjustment mechanism and rotating mechanism.
Preferably, the attitude-adjusting system includes X, and tri- axis of Y, Z translates adjustment mechanism and around X, tri- axis rotations of Y, Z
Three axis adjusting mechanisms.
Preferably, radial direction shafting and thrust coupling of shaft system are passed through between the pedestal and turntable.
Preferably, the turntable lower end is also associated with being used for transmission the slip ring of electric signal and data-signal, the cunning
The slip ring reading stent being fixed on the pedestal is provided with below ring.
Preferably, the turntable center is provided with torque motor.
Preferably, the base bottom is provided with leveling lower margin.
The beneficial effects of the utility model are：The high contrast low dosage phase contrast CT image-forming device of the utility model can
Larger penetration depth is realized using the X source of high-energy, so as to the high lining applied to thick sample (tens centimetres) or even human body
Degree, low dose imaging, the utility model can substantially reduce the dose of radiation that sample is received.And the imaging dress of the utility model
Sample stage rotation can be realized and realize that imaging system rotates by putting, reliable and stable, to be capable of providing the imaging technique required
Required precision.Tthe utility model system stability is high, is easily installed manufacture, and easy to operate, is well positioned to meet user demand,
Have a vast market prospect.
Description of the drawings
Fig. 1 is the structure diagram of the high contrast low dosage phase contrast CT image-forming device of the utility model；
Fig. 2 is the sectional view of the high contrast low dosage phase contrast CT image-forming device of the utility model；
Fig. 3 is the structure diagram of the sample stage of the high contrast low dosage phase contrast CT image-forming device of the utility model；
Fig. 4 is the structure diagram of the source grating of the high contrast low dosage phase contrast CT image-forming device of the utility model；
Fig. 5 is the structural representation of the beam-splitting optical grating of the high contrast low dosage phase contrast CT image-forming device of the utility model
Figure.
Reference sign：
1-pedestal；2-turntable；3-imaging platform；4-sample stage；5-radial direction shafting；6-thrust shafting；7-sliding
Ring；8-slip ring reading stent；9-torque motor；10-leveling lower margin；30-X-ray source；31-source grating；32-beam splitting
Grating；33-perforate；34-analysis grating；35-detector；36-micro-displacement stepping mechanism；37-attitude-adjusting system；
38-heat-proof device；40-elevating mechanism；41-planar adjustment mechanism；42-rotating mechanism；310-diaphragm mechanism；370-three
Axis translates adjustment mechanism；371-three axis adjusting mechanisms 371.
Specific embodiment
The utility model is described in further detail with reference to embodiment, those skilled in the art's reference to be made to say
Bright book word can be implemented according to this.
It should be appreciated that such as " having ", "comprising" and " comprising " term used herein are not precluded from one or more
The presence or addition of a other elements or its combination.
As shown in Figs. 1-5, a kind of high contrast low dosage phase contrast CT image-forming device of the present embodiment, including：Pedestal 1,
The turntable 2 for being arranged at 1 top of pedestal, the imaging platform 3 being arranged on turntable 2 and insertion vertically are arranged on turntable 2
The sample stage 4 of internal circle centre position；In imaging platform 3 X-ray source 30, source grating 31, beam splitting are disposed with along optical path direction
Grating 32, the top for sample stage 4 are stretched the perforate 33 being pierced by, analysis grating 34 and detector 35；Pedestal 1 and turntable 2 it
Between connected by radial direction shafting 5 and thrust shafting 6；2 center of turntable is provided with torque motor 9；Sample stage 4 includes elevating mechanism
40th, planar adjustment mechanism 41 and rotating mechanism 42, elevating mechanism 40 realize the axial lifting of sample stage 4, and rotating mechanism 42 is realized
Sample stage 4 is adjusted around axial rotation, and planar adjustment mechanism 41 leads to for adjusting the displacement of rotating mechanism 42 in the horizontal direction
The position of the horizontal direction of the sample on rotating mechanism 42 is overregulated, the size of the scanning range of X-ray source 30 is adjusted；Into
As the material selection granite of platform 3；1 bottom of pedestal is provided with leveling lower margin 10.
Source grating 31, beam-splitting optical grating 32 and analysis grating 34 are arc shape, and the center of circle is respectively positioned at X-ray source 30.
Source grating 31 and 32 lower end of beam-splitting optical grating are both provided with attitude-adjusting system 37.Attitude-adjusting system 37 includes X, Y,
Tri- axis of Z translates adjustment mechanism 370 and around X, three axis adjusting mechanism 371 of tri- axis rotations of Y, Z.Three axis translate adjustment mechanism 370
Realize X, the motor adjustment in tri- direction of Y, Z, three axis adjusting mechanisms 371 realize that the rotation of tri- axis of Z is adjusted, so as to pass through around X, Y
Attitude-adjusting system 37 is used to implement the adjusting of front-rear direction up and down and three direction of rotation.It is additionally provided on adjusting mechanism
Retaining mechanism.
It is additionally provided with to adjust the diaphragm mechanism 310 of X-ray incidence range, X-ray source 30 and source in source grating 31
Heat-proof device 38 is provided between grating 31.
32 lower end of beam-splitting optical grating is provided with micro-displacement stepping mechanism 36, and micro-displacement stepping mechanism 36 includes flexure hinge mechanism
With piezoelectric ceramics pushing mechanism.
2 lower end of turntable is also associated with being used for transmission the slip ring 7 of electric signal and data-signal, slip ring 7 and the rotation of upper end
Electric signal on platform 2 is connected with data signal transmission wire, and 7 lower section of slip ring is provided with the slip ring reading stent being fixed on pedestal 1
8.Slip ring reading stent 8 is used for the electric signal of slip ring 7 and data signal transmission to external controller.
When high contrast low dosage phase contrast CT image-forming device carries out sample detection, by x-ray bombardment sample, and carry out
Data acquisition, to obtain CT images.Its principle can be explained as follows：
X source is a light source for launching cone-beam x-ray.Source grating 31 is located at the focus 100mm apart from X source, by
There is geometry amplification factor in imaging system, therefore the area of source grating 31 is not necessarily to too greatly, as long as it is on detector 35
Projection more than detector 35 receiving area, above technique for, the smaller grating of area is easier processing and fabricating,
It more can guarantee its uniformity, and it is at low cost.Source grating 31 includes diaphragm mechanism 31, for adjusting X-ray incidence range, so
In imaging process below, detector 35 can be made only to receive photon in the region for having Moire fringe, diaphragm is made to block completely
Directive does not have the photon in Moire fringe region, can so improve the accuracy that detector 35 gathers image, increases detector 35
Service life.
Beam-splitting optical grating 32 is arranged at X source focus 400mm, and analysis grating 34 is arranged at X source focal point 1600mm,
Sample stage 4 is located at the circle centre position of turntable 2, is arranged at behind beam-splitting optical grating 32, and detector 35 is arranged at analysis grating 34
Below.
To ensure the precision of imaging system, the circular runout of turntable main shaft is no more than 10 microns, and axial float error is no more than
37 microns, turntable positioning accuracy is no more than 0.1rad.
During imaging, the X source of millimeter magnitude is divided into a series of line source by source grating 31 first, to each line source
For, its Spatially coherent length at beam-splitting optical grating 32 is more than the cycle of beam-splitting optical grating 32, and such beam-splitting optical grating 32 is relevant
Under optical illumination, it can be formed by hooligan's effect at 34 position of analysis grating from imaging,
Then by Lau effects, what beam-splitting optical grating 32 generated under each linear light source lighting can be mutually wrong from imaged striation
A cycle is opened, is superimposed so as to noncoherent, can greatly be strengthened from the intensity of imaged striation.
Then beam-splitting optical grating 32 from imaged striation and analysis grating 34 can form Moire fringe, if beam-splitting optical grating 32
It from imaged striation and analyzes between the striped of grating 34 there are one small angle, or beam-splitting optical grating 32 is from the week of imaged striation
There are small difference between phase and the cycle for analyzing grating 34, then passing behind X-ray detector 35 in analysis grating 34
It can detect cycle very big Moire fringe.
Then, X-ray can reflect when through sample, and the deviation of light can cause the torsion of moire pattern shapes
Song is embodied in actual tests, is the variation of pixel light intensity.It is by measuring the variation of each image pixel intensities, i.e., available
The refraction image of sample.
In one embodiment, the data acquisition of the high contrast low dosage phase contrast CT image-forming device (is imaged
Process) comprise the following steps：
Step 1：Gather no sample when beam-splitting optical grating 32 be respectively at it is preset first acquisition position, second acquisition position,
The data that detect of detector 35 when the 3rd acquisition position and the 4th acquisition position, using collect four groups of data as above-mentioned
The background intensity of four acquisition positions；
Step 2：The data acquisition of each tomography of sample is carried out, is specifically included：
Step 2-1：Fixed beam-splitting optical grating 32 to the first gathers position；
Step 2-2：Turntable 2 is controlled to be rotated with the rotating speed of 0.5 cycle per second, control detector 35 is with rates of the 2.5ms per frame
Gathered data, turntable 2 stop acquisition after rotating a circle；
Step 2-3：By micro-displacement stepping mechanism 36 beam-splitting optical grating 32 is driven to be moved to the second acquisition position, repeat step 2-
2；
Step 2-4：By micro-displacement stepping mechanism 36 beam-splitting optical grating 32 is driven to be moved to the 3rd acquisition position, repeat step 2-
2；
Step 2-5：By micro-displacement stepping mechanism 36 beam-splitting optical grating 32 is driven to be moved to the 4th acquisition position, repeat step 2-
2, complete the data acquisition of a tomography of sample；
Step 3：Control sample stage 4 is axially moveable the distance of setting, step 2 is repeated, to carry out next fan of sample
The data acquisition of beam tomography；
Step 4：Data separating reconstructs：Beam-splitting optical grating 32 in each tomography of the sample gathered by above-mentioned steps is in four
Collect 4 groups of data during a acquisition position are respectively combined as a sets of data, data acquisition.It is follow-up to carry out data point again
It is reconstructed from CT.Wherein, data separating is carried out using the method identical with traditional PS scheme to reconstruct with CT.
The above is only the introduction to the workflow of the utility model, the utility model not to the method that is directed into
Any improvement of row.
Wherein, 4 acquisition positions along arc-shaped beam-splitting optical grating 32 arc extended line arrange, i.e., 4 acquisition positions and
Beam-splitting optical grating 32 is on same circumference, therefore when carrying out data acquisition, beam-splitting optical grating 32 need to be made to do movement in a curve, pass through piezoelectricity
Ceramic pushing mechanism is driven, and beam-splitting optical grating 32 is promoted to move, and is carried out displacement limitation by flexure hinge mechanism, is limited beam splitting light
The moving line of grid 32 is camber line, so as to realize the movement in a curve of beam-splitting optical grating 32 by micro-displacement stepping mechanism 36.
It in another embodiment, can not be turned with imaging system, the imaging of object is realized by the rotation of sample stage 4.
Although the embodiment of the utility model is disclosed as above, it is not restricted in specification and embodiment
Listed utilization, it can be applied to the field of various suitable the utility model completely, for those skilled in the art,
Other modification is easily achieved, therefore without departing from the general concept defined in the claims and the equivalent scope, this reality
Specific details is not limited to new.
Claims (9)
1. a kind of high contrast low dosage phase contrast CT image-forming device, which is characterized in that including：Pedestal is arranged at the pedestal
The turntable of top, the imaging platform being arranged on the turntable and insertion vertically are arranged on the center of circle inside the turntable
The sample stage at place；
In the imaging platform along optical path direction be disposed with X-ray source, source grating, beam-splitting optical grating, for the sample stage
Top stretch the perforate being pierced by, analysis grating and detector；
The beam-splitting optical grating lower end is provided with micro-displacement stepping mechanism, the micro-displacement stepping mechanism include flexure hinge mechanism and
Piezoelectric ceramics pushing mechanism；
The source grating and beam-splitting optical grating lower end are both provided with attitude-adjusting system；
Source grating, beam-splitting optical grating and the analysis grating is arc shape, and the center of circle is respectively positioned at the X-ray source.
2. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the source grating
On be additionally provided with to adjust the diaphragm mechanism of X-ray incidence range.
3. high contrast low dosage phase contrast CT image-forming device according to claim 2, which is characterized in that the X-ray
Heat-proof device is provided between light source and source grating.
4. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the sample stage
Including elevating mechanism, planar adjustment mechanism and rotating mechanism.
5. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the posture tune
Complete machine structure includes X, tri- axis of Y, Z translation adjustment mechanism and the three axis adjusting mechanisms rotated around X, tri- axis of Y, Z.
6. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the pedestal with
Pass through radial direction shafting and thrust coupling of shaft system between turntable.
7. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the turntable
Lower end is also associated with being used for transmission the slip ring of electric signal and data-signal, is provided with and is fixed on the pedestal below the slip ring
Slip ring reading stent.
8. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the turntable
Center is provided with torque motor.
9. high contrast low dosage phase contrast CT image-forming device according to claim 1, which is characterized in that the pedestal bottom
Portion is provided with leveling lower margin.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107748341A (en) * | 2017-10-23 | 2018-03-02 | 中国科学院苏州生物医学工程技术研究所 | High contrast low dosage phase contrast CT image-forming device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107748341A (en) * | 2017-10-23 | 2018-03-02 | 中国科学院苏州生物医学工程技术研究所 | High contrast low dosage phase contrast CT image-forming device |
| CN107748341B (en) * | 2017-10-23 | 2024-08-13 | 中国科学院苏州生物医学工程技术研究所 | High-contrast low-dose phase contrast CT imaging device |
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