CN207429159U - Operation guiding system based near infrared imaging - Google Patents
Operation guiding system based near infrared imaging Download PDFInfo
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- CN207429159U CN207429159U CN201720391305.9U CN201720391305U CN207429159U CN 207429159 U CN207429159 U CN 207429159U CN 201720391305 U CN201720391305 U CN 201720391305U CN 207429159 U CN207429159 U CN 207429159U
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- operation guiding
- infrared fluorescent
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Abstract
The utility model discloses a kind of operation guiding system based near infrared imaging, including：Near infrared image probe for targeting the pathological tissues for needing surgery excision, and can generate near-infrared fluorescent signal under the irradiation of exciting light；Interior snooping head, including：Excitation light source, to generate the exciting light, near-infrared fluorescent collector, to gather the near-infrared fluorescent signal；Image workstation, at least to by the near-infrared fluorescent signal be converted to digitized video and build corresponding to operative site three-dimensional scenic；And virtual reality display device, at least to by the three-dimensional scenic to operator present.The operation guiding system of the utility model possesses high sensitivity, movement is flexible, design and develop, operates the features such as simple, information is reliable, safe, it can be had a wide range of applications with guiding in real time tumor resection in pharmaceutical indications and curative effect evaluation, drug metabolism distribution, tumour early detection, stem cell differentiation with fields such as reparations.
Description
Technical field
The utility model is specifically related to a kind of operation guiding system based near infrared imaging, belongs to medical instruments field.
Background technology
Global 5,000,000 tumor patient of all having more than every year has carried out Oncological Surgery resection operation, this is also at present most
Effective cancer immunotherapies.Reliably accurately surgery excision can save the life of ten hundreds of patients.In Oncological Surgery hand
In art, tumour identification, definite and metastatic lymph node discriminating of tumor resection margin etc. are an important factor for influencing tumor prognosis.
Beeline under mirror after primary tumor excision between the edge and cancerous tissue of sample, it is an important finger for evaluating tumor operation
An important factor for marking and influencing tumor prognosis, and most of tumor resection all fails excision totally at present, causes to recur
And transfer, so that losing life.
Two area's fluorescence of near-infrared（NIR-II 1000-1700 nm）Than traditional one area fluorescence (400- of visible and near-infrared
900 nm) there is deeper penetration into tissue and lower scattering, it can also be detected even if the smaller target of deeper.It is and thin
The autofluorescence of born of the same parents and tissue is minimum in two area's wave band of near-infrared, therefore in detection of complex biosystem, 2nd area of near-infrared is glimmering
Light probe can provide higher specificity and sensitivity.Near infrared fluorescent probe specific marker is used in tumor resection is tidied up
After tumor locus, it can be seen that fluorescence signal has stronger signal in borderline tumor position compared with tumor center, clearly indicates tumour
It with the border of periphery health tissues, and distinguishes, and illustrates swollen there is no the fluorescence of tumor molecular marker in incisxal edge part
Knurl is also thoroughly removed.The tumor resection of near-infrared 2nd area fluorescence guiding can accurately determine tumour incisxal edge, reduce to healthy group
The infringement knitted minimizes the pain of patient.
The content of the invention
The main purpose of the utility model is that a kind of operation guiding system based near infrared imaging is provided, it is existing to overcome
There is the deficiency in technology.
To realize foregoing purpose of utility model, the technical solution adopted in the utility model includes：
The utility model embodiment provides a kind of operation guiding system based near infrared imaging, including：
Near infrared image probe, at least for targeting the pathological tissues for needing surgery excision, and can be in the photograph of exciting light
Penetrate lower generation near-infrared fluorescent signal；
Interior snooping head, including：
Excitation light source, at least to generate the exciting light,
Near-infrared fluorescent collector, at least gathering the near-infrared fluorescent signal of the near infrared image probe emission；
Image workstation, at least the near-infrared fluorescent signal the near-infrared fluorescent collector to be gathered are converted to number
Word image simultaneously builds the three-dimensional scenic corresponding to operative site；
And virtual reality display device, at least to by the three-dimensional scenic that the image workstation is built to operator
It presents.
Further, it is described it is interior snooping head further include locator, at least to it is described it is interior snooping head in three dimensions
Position carry out in real time track and position；The image workstation is mapped according to the locator in the coordinate of different position to close
It is the three-dimensionalreconstruction that operative site is carried out to the digitized video, so as to form the three-dimensional scenic.
Further, the fluorescence emission wavelengths scope of the near infrared image probe is 1000-1700 nm.
Further, the excitation light source is set around the near-infrared fluorescent collector.
Further, the excitation light source is arranged on the outer ring portion of the interior snooping head, the near-infrared fluorescent collector
It is arranged on inside the interior snooping head.
Further, the wavelength of the exciting light of the excitation light source transmitting is 700-1350nm.
Further, the near-infrared fluorescent collector further includes dismountable optical filter.
Further, the image workstation includes：
Near-infrared fluorescent detector, at least the near-infrared fluorescent signal the near-infrared fluorescent collector to be gathered turn
It is changed to digitized video；
Computer carries out Surgery depending at least on coordinate mapping relations of the locator in different position to the digitized video
The three-dimensionalreconstruction of position, so as to form the three-dimensional scenic.
Further, the fluorescent signals wavelengths of the near-infrared fluorescent explorer response are 400-1700 nm.
Further, the virtual reality display device includes virtual reality glasses, and the virtual reality display device
It is connected by wired or wireless way with image workstation.
In some more specific embodiment, the operation guiding system includes：Near infrared image probe, interior snooping
Head, image workstation and virtual reality glasses.
The near infrared image probe for targeting the pathological tissues for needing surgery excision, and generates near-infrared fluorescent letter
Number；
The interior snooping head, for exciting, gathering near-infrared fluorescent signal and positioning；
The image workstation, the fluorescence signal interior snooping head to be collected is converted into digitized video, and carries out three
Dimension reconstruct, forms three-dimensional modeling scene；
The virtual reality glasses, for the three-dimensional scenic with feeling of immersion of image workstation formation to be presented.
Further, the operation guiding system based near infrared imaging, the near infrared image fluorescence probe
Launch wavelength scope 1000-1700 nm.
Further, the interior snooping head includes excitation light source and near-infrared fluorescent collector, and excitation light source is used to excite
The near-infrared fluorescent image probe of pathological tissues is targeted in advance, it is made to generate two area's fluorescence signal of near-infrared, near-infrared fluorescent
Collector captures fluorescence signal and is transferred to image workstation.
Further, the excitation light source wave-length coverage is 700-1350 nm, and according to actual demand, power can be continuous
It adjusts.
Further, the near-infrared fluorescent collector further includes dismountable optical filter and locator, and optical filter can be with
Filter the interference fluorescence of excitation light source, position of the locator for definite interior snooping head in three dimensions.
Further, the image workstation includes near-infrared fluorescent detector and computer, near-infrared fluorescent detector
Near-infrared fluorescent signal for near-infrared fluorescent collector to be collected changes into digitized video, and then computer is by digital shadow
As carrying out three-dimensionalreconstruction, three-dimensional modeling scene is formed.
Further, the fluorescent signals wavelengths of the near-infrared fluorescent explorer response are 400-1700 nm.
Further, virtual reality glasses are a kind of wearable devices, and doctor can be worn on eyes, pass through data cable
Or WLAN or bluetooth are connected with computer.Having for image workstation formation will be presented to doctor in the virtual reality glasses
The three-dimensional scenic of feeling of immersion makes operation more accurately, reliably, quickly, conveniently.
Compared with the prior art, the operation guiding system of the utility model
Possess high sensitivity, it is mobile flexibly, design and develop, operate the features such as simple, information is reliable, safe, be outside
The good assistant of section doctor, can be with guiding in real time tumor resection.In pharmaceutical indications and curative effect evaluation, drug metabolism distribution, swell
Knurl early detection, stem cell differentiation have a wide range of applications with fields such as reparations.
Description of the drawings
Fig. 1 is that a kind of structure of the operation guiding system based near infrared imaging is shown in one exemplary embodiments of the utility model
It is intended to.
Reference sign：Near infrared image probe 1, excitation light source 2, near-infrared fluorescent collector 3, near-infrared fluorescent are visited
Survey device 4, computer 5, virtual reality glasses 6.
Specific embodiment
For the purpose of this utility model, technical solution and advantage is more clearly understood, below in conjunction with specific embodiment, and
Referring to the drawings, the utility model is further described.
As shown in Figure 1, the utility model belongs to a kind of operation guiding system based near infrared imaging, including：It is near red
Outer image probe 1, interior snooping head, image workstation and virtual reality glasses 6.
Wherein, for interior snooping head again comprising excitation light source 2 and near-infrared fluorescent collector 3, image workstation includes near-infrared
Fluorescent probe 4 and computer 5.
First, before the surgery, first choose suitable near infrared image probe 1 and have target to the pathological tissues of surgery excision
To the targeted molecular of effect, then by the two modification together, the targeted molecular with fluorescence labelling is formed, before the start of the surgery
It is locally implanted in patient body, the targeted molecular with fluorescence labelling can be targeted to rapidly pathological tissues.The near infrared image is visited
1 fluorescence emission wavelengths scope 1000-1700 nm of pin.
Excitation light source 2 is arranged on the outside of interior snooping head, and entire outer ring is excitation light source 2, and excitation light source 2 can be equably
Excitation beam is sent, wave-length coverage is 700-1350 nm, can adjust watt level so that near-infrared shadow according to actual demand
As probe 1 launches the near-infrared fluorescent of proper strength, convenient for imaging below and the visual experience of doctor.Near-infrared fluorescent is adopted
Storage 3 is arranged on the inside of interior snooping head, for gathering the fluorescence signal that near infrared fluorescent probe 1 is sent.Near-infrared fluorescent is adopted
3 inside of storage is equipped with removably optical filter, to filter the interference fluorescence collected.In operation, interior snooping head can be consolidated
It is scheduled on stent, doctor can also take, and can also be fixed on operable robotic arm, pass through computer remote control
System, doctor to be aided in carry out surgical navigational.Locator is also equipped in interior snooping head, it can be according to interior snooping head in three dimensions
Position carry out in real time track, position, and assisted image work station carry out three-dimensional imaging.
Near-infrared fluorescent detector 5 in image workstation is connected by data cable with interior snooping head, to by interior snooping
Real-time fluorescent signals are converted into digitized video in the art that head collects, and in the computer 5 being transferred in image workstation, preferably
, the computer 5 of present embodiment is internally spied upon according to the interior locator spied upon in head in the coordinate mapping relations of different position
A series of real-time fluorescence images that head obtains carry out the three-dimensionalreconstruction of operative site, form three-dimensional modeling scene.Wherein, it is described near
The fluorescent signals wavelengths that IR fluorescence detector 4 responds are 400-1700 nm.
Virtual reality glasses 6, are a kind of wearable devices, and computer passes through data cable or WLAN or Bluetooth transmission
To virtual reality glasses 6, doctor is worn on eyes, which will be presented image workstation to doctor and be formed
The three-dimensional scenic with feeling of immersion, accurately determine tumour incisxal edge, instruct the optimal nearest operation pathway of doctor's selection, reduce
Infringement to health tissues, and avoid important human organ, it is ensured that operation safety smoothly carries out, and the pain of patient is dropped
It is extremely minimum.
Preferably, present embodiment is particularly evident to tumor resection effect.
The various embodiments described above only express the several embodiments of the utility model, and description is more specific and detailed, but
It should not be interpreted as limiting the scope of the present invention.It should be pointed out that the common skill for this field
For art personnel, without departing from the concept of the premise utility, various modifications and improvements can be made, these are belonged to
The scope of protection of the utility model.Therefore, the protection domain of the utility model patent should be determined by the appended claims.
Claims (10)
1. a kind of operation guiding system based near infrared imaging, it is characterised in that including：
Near infrared image probe, at least for targeting the pathological tissues for needing surgery excision, and can be under the irradiation of exciting light
Generate near-infrared fluorescent signal；
Interior snooping head, including：
Excitation light source, at least to generate the exciting light,
Near-infrared fluorescent collector, at least gathering the near-infrared fluorescent signal of the near infrared image probe emission；
Image workstation, at least the near-infrared fluorescent signal the near-infrared fluorescent collector to be gathered are converted to digital shadow
Picture simultaneously builds the three-dimensional scenic corresponding to operative site；
And virtual reality display device, at least to by the three-dimensional scenic that the image workstation is built to operator present.
2. the operation guiding system according to claim 1 based near infrared imaging, it is characterised in that：The interior snooping head
Locator is further included, at least to the position progress tracking in real time and positioning to the interior snooping head in three dimensions；Institute
It states image workstation and operative site is carried out to the digitized video according to coordinate mapping relations of the locator in different position
Three-dimensionalreconstruction, so as to form the three-dimensional scenic.
3. the operation guiding system according to claim 1 based near infrared imaging, it is characterised in that：The near-infrared shadow
As the fluorescence emission wavelengths scope of probe is 1000-1700 nm.
4. the operation guiding system according to claim 1 based near infrared imaging, it is characterised in that：The excitation light source
It is set around the near-infrared fluorescent collector.
5. the operation guiding system according to claim 4 based near infrared imaging, it is characterised in that：The excitation light source
The outer ring portion of the interior snooping head is arranged on, the near-infrared fluorescent collector is arranged on inside the interior snooping head.
6. the operation guiding system according to claim 3 based near infrared imaging, it is characterised in that：The excitation light source
The wavelength of the exciting light of transmitting is 700-1350nm.
7. the operation guiding system according to claim 1 based near infrared imaging, it is characterised in that：The near-infrared is glimmering
Light collector further includes dismountable optical filter.
8. the operation guiding system according to claim 2 based near infrared imaging, which is characterized in that the image work
Station includes：
Near-infrared fluorescent detector, at least the near-infrared fluorescent signal the near-infrared fluorescent collector to be gathered are converted to
Digitized video；
Computer carries out operative site depending at least on coordinate mapping relations of the locator in different position to the digitized video
Three-dimensionalreconstruction, so as to form the three-dimensional scenic.
9. the operation guiding system according to claim 8 based near infrared imaging, it is characterised in that：The near-infrared is glimmering
The fluorescent signals wavelengths of optical detector response are 400-1700 nm.
10. the operation guiding system according to claim 1 based near infrared imaging, it is characterised in that：It is described virtual existing
Real display device includes virtual reality glasses, and the virtual reality display device is worked by wired or wireless way and image
It stands connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720391305.9U CN207429159U (en) | 2017-04-14 | 2017-04-14 | Operation guiding system based near infrared imaging |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720391305.9U CN207429159U (en) | 2017-04-14 | 2017-04-14 | Operation guiding system based near infrared imaging |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106937884A (en) * | 2017-04-14 | 2017-07-11 | 苏州影睿光学科技有限公司 | Operation guiding system based near infrared imaging |
| CN109846531A (en) * | 2019-02-26 | 2019-06-07 | 河南亚都实业有限公司 | Hysteromyomectomy negative pressure catheter |
| CN113952033A (en) * | 2021-12-21 | 2022-01-21 | 广东欧谱曼迪科技有限公司 | Double-source endoscopic surgery navigation system and method |
-
2017
- 2017-04-14 CN CN201720391305.9U patent/CN207429159U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106937884A (en) * | 2017-04-14 | 2017-07-11 | 苏州影睿光学科技有限公司 | Operation guiding system based near infrared imaging |
| CN109846531A (en) * | 2019-02-26 | 2019-06-07 | 河南亚都实业有限公司 | Hysteromyomectomy negative pressure catheter |
| CN109846531B (en) * | 2019-02-26 | 2023-11-21 | 河南亚都实业有限公司 | Suction catheter for hysteromyectomy |
| CN113952033A (en) * | 2021-12-21 | 2022-01-21 | 广东欧谱曼迪科技有限公司 | Double-source endoscopic surgery navigation system and method |
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