CN206454651U - A kind of irinotecan hydrochloride reactor - Google Patents

A kind of irinotecan hydrochloride reactor Download PDF

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Publication number
CN206454651U
CN206454651U CN201720103692.1U CN201720103692U CN206454651U CN 206454651 U CN206454651 U CN 206454651U CN 201720103692 U CN201720103692 U CN 201720103692U CN 206454651 U CN206454651 U CN 206454651U
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China
Prior art keywords
fixedly connected
kettle
hanger
irinotecan hydrochloride
vertical rod
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Expired - Fee Related
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CN201720103692.1U
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Chinese (zh)
Inventor
戴勇强
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Shun Quan Bio Tech Ltd Jiangxi
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Shun Quan Bio Tech Ltd Jiangxi
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Abstract

The utility model discloses a kind of irinotecan hydrochloride reactor, including kettle and electric expansion bar, the bottom of the kettle is fixedly connected with the first montant, the second montant is fixedly connected with the top of the kettle, one end of the remote kettle of second montant is flexibly connected hanger by the first oscillating bearing, the hanger is in frame-like, and the bottom of hanger is fixedly connected with motor, rotating disk is fixedly connected with the rotor of the motor, vertical rod is fixedly connected with the top of the rotating disk, the vertical rod is flexibly connected one end of connecting rod by bearing, the one end of the connecting rod away from vertical rod is flexibly connected the first montant by second joint bearing;Some groups of standing fixing devices are provided with the hanger;Strip projecting block is evenly arranged with the inwall of the kettle.This irinotecan hydrochloride reactor has the features such as being difficult pollution kettle substance in vivo and good mixing effect.

Description

一种盐酸伊立替康反应釜A kind of irinotecan hydrochloride reaction kettle

技术领域technical field

本实用新型涉及反应釜技术领域,具体为一种盐酸伊立替康反应釜。The utility model relates to the technical field of reaction kettles, in particular to an irinotecan hydrochloride reaction kettle.

背景技术Background technique

盐酸伊立替康注射液,适应症为本品适用于晚期大肠癌患者的治疗,在其制备中需要混合山梨醇,乳酸和注射用水,而在制备中需使用到反应釜。反应釜的广义理解即有物理或化学反应的容器,现有的反应釜的搅拌装置大多设置在釜体内,这种设计润滑油十分容易自搅拌装置转动轴流入釜体内部,因而容易污染釜体内物质,因此此种反应釜不适用于盐酸伊立替康注射液的制备。为此,我们提出一种盐酸伊立替康反应釜。The indication of irinotecan hydrochloride injection is that this product is suitable for the treatment of patients with advanced colorectal cancer. It needs to mix sorbitol, lactic acid and water for injection in its preparation, and a reaction kettle needs to be used in the preparation. The broad understanding of the reaction kettle is a container for physical or chemical reactions. Most of the stirring devices of the existing reaction kettles are installed in the kettle body. This design lubricating oil is very easy to flow into the interior of the kettle body from the rotating shaft of the stirring device, so it is easy to pollute the kettle body. Substances in the body, so this kind of reactor is not suitable for the preparation of irinotecan hydrochloride injection. For this reason, we propose a kind of irinotecan hydrochloride reactor.

实用新型内容Utility model content

本实用新型解决的技术问题在于克服现有技术易污染釜体内物质和混合效果差的缺陷,提供一种盐酸伊立替康反应釜。所述盐酸伊立替康反应釜具有不易污染釜体内物质和混合效果好等特点。The technical problem solved by the utility model is to overcome the defects in the prior art that the materials in the kettle are easily polluted and the mixing effect is poor, and provide an irinotecan hydrochloride reaction kettle. The irinotecan hydrochloride reaction kettle has the characteristics of not easily polluting the materials in the kettle body, good mixing effect, and the like.

为实现上述目的,本实用新型提供如下技术方案:一种盐酸伊立替康反应釜,包括釜体和电动伸缩杆,所述釜体的底部固定连接有第一竖杆,所述釜体的顶部固定连接有第二竖杆,所述第二竖杆的远离釜体的一端通过第一关节轴承活动连接挂架,所述挂架呈框架状,且挂架的底部固定连接有电机,所述电机的转子上固定连接有转盘,所述转盘的顶部固定连接有立杆,所述立杆通过轴承活动连接连接杆的一端,所述连接杆远离立杆的一端通过第二关节轴承活动连接第一竖杆;所述挂架上设置有若干组静置固定装置;所述釜体的内壁上均匀设置有条状突出块。In order to achieve the above object, the utility model provides the following technical scheme: a reaction kettle for irinotecan hydrochloride, comprising a kettle body and an electric telescopic rod, the bottom of the kettle body is fixedly connected with a first vertical rod, and the top of the kettle body A second vertical rod is fixedly connected, and the end of the second vertical rod away from the kettle body is movably connected to the hanger through the first joint bearing. The hanger is in the shape of a frame, and the bottom of the hanger is fixedly connected with a motor. The rotor of the motor is fixedly connected with a turntable, and the top of the turntable is fixedly connected with a vertical rod. The vertical rod is movably connected to one end of the connecting rod through a bearing, and the end of the connecting rod far away from the vertical rod is movably connected to the second joint bearing. A vertical bar; several groups of static fixing devices are arranged on the hanger; strip-shaped protruding blocks are evenly arranged on the inner wall of the kettle body.

优选的,所述静置固定装置至少有一组,且每组静置固定装置包括两个夹持装置,且两个夹持装置相对设置。Preferably, there is at least one set of static fixing devices, and each set of static fixing devices includes two clamping devices, and the two clamping devices are arranged opposite to each other.

优选的,所述夹持装置包括贴合板,所述贴合板的一侧固定连接电动伸缩杆的伸出端,所述电动伸缩杆远离贴合板的一端固定连接挂架。Preferably, the clamping device includes a fitting board, one side of the fitting board is fixedly connected to the extended end of the electric telescopic rod, and the end of the electric telescopic rod away from the fitting board is fixedly connected to the hanger.

优选的,所述贴合板远离电动伸缩杆的一侧设置有橡胶防滑垫,且贴合板呈弧形。Preferably, a rubber anti-skid pad is provided on the side of the fitting board away from the electric telescopic rod, and the fitting board is arc-shaped.

优选的,所述立杆的位置远离转盘的轴心。Preferably, the position of the upright rod is far away from the axis of the turntable.

与现有技术相比,本实用新型的有益效果是:本盐酸伊立替康反应釜具有不易污染釜体内物质和混合效果好等特点。本反应釜通过电机、转盘和连接杆带动釜体摇晃实现混合的功能,不在釜体内设置搅拌桨,从而不会污染釜体内物质;釜体的内壁上均匀设置有条状突出块,在使用时随着釜体的摇晃,内部的制备液在条状突出块的作用下激荡更加激烈,提高了混合效果。Compared with the prior art, the utility model has the beneficial effects that: the irinotecan hydrochloride reaction kettle has the characteristics of not being easy to pollute the materials in the kettle and good mixing effect. The reaction kettle drives the kettle body to shake through the motor, turntable and connecting rod to realize the mixing function. There is no stirring paddle in the kettle body, so as not to pollute the materials in the kettle body; With the shaking of the kettle body, the internal preparation liquid is agitated more violently under the action of strip-shaped protruding blocks, which improves the mixing effect.

附图说明Description of drawings

图1为本实用新型结构示意图;Fig. 1 is a structural representation of the utility model;

图2为本实用新型夹持装置结构示意图;Fig. 2 is a structural schematic diagram of the clamping device of the present invention;

图3为本实用新型釜体截面结构示意图。Fig. 3 is a schematic diagram of the section structure of the kettle body of the present utility model.

图中:1釜体、2第二竖杆、3第一关节轴承、4挂架、5第一竖杆、6电机、7转盘、8立杆、9第二关节轴承、10连接杆、11静置固定装置、12夹持装置、121贴合板、122橡胶防滑垫、13电动伸缩杆、14条状突出块。In the figure: 1 kettle body, 2 second vertical rod, 3 first joint bearing, 4 hanger, 5 first vertical rod, 6 motor, 7 turntable, 8 vertical rod, 9 second joint bearing, 10 connecting rod, 11 Static fixing device, 12 clamping device, 121 laminating board, 122 rubber anti-skid pad, 13 electric telescopic rod, 14 strip-shaped protruding blocks.

具体实施方式detailed description

下面将结合本实用新型实施例中的附图,对本实用新型实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本实用新型一部分实施例,而不是全部的实施例。基于本实用新型中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本实用新型保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. example. Based on the embodiments of the present utility model, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of the present utility model.

请参阅图1,本实用新型提供一种技术方案:一种盐酸伊立替康反应釜,包括釜体1和电动伸缩杆13,所述釜体1的底部固定连接有第一竖杆5,所述釜体1的顶部固定连接有第二竖杆2,所述第二竖杆2的远离釜体1的一端通过第一关节轴承3活动连接挂架4,所述挂架4呈框架状,且挂架4的底部固定连接有电机6,所述电机6 的转子上固定连接有转盘7,所述转盘7的顶部固定连接有立杆8,所述立杆8的位置远离转盘7的轴心,所述立杆8通过轴承活动连接连接杆10的一端,所述连接杆10远离立杆8的一端通过第二关节轴承9活动连接第一竖杆5;所述挂架4上设置有若干组静置固定装置 11,所述静置固定装置11至少有一组,且每组静置固定装置11包括两个夹持装置12,且两个夹持装置12相对设置,所述夹持装置12包括贴合板121,所述贴合板121远离电动伸缩杆13的一侧设置有橡胶防滑垫122,且贴合板121呈弧形,所述贴合板121的一侧固定连接电动伸缩杆13的伸出端,所述电动伸缩杆13远离贴合板121的一端固定连接挂架4;所述釜体1的内壁上均匀设置有条状突出块14。Please refer to Fig. 1, the utility model provides a kind of technical scheme: a kind of irinotecan hydrochloride reaction kettle, comprises kettle body 1 and electric telescopic rod 13, the bottom of described kettle body 1 is fixedly connected with the first vertical rod 5, so The top of the kettle body 1 is fixedly connected with a second vertical rod 2, and the end of the second vertical rod 2 away from the kettle body 1 is flexibly connected to the hanger 4 through the first joint bearing 3, and the hanger 4 is in a frame shape, And the bottom of hanger 4 is fixedly connected with motor 6, and the rotor of described motor 6 is fixedly connected with turntable 7, and the top of described turntable 7 is fixedly connected with upright bar 8, and the position of described upright bar 8 is away from the axis of turntable 7. Center, the vertical rod 8 is movably connected to one end of the connecting rod 10 through a bearing, and the end of the connecting rod 10 away from the vertical rod 8 is flexibly connected to the first vertical rod 5 through the second joint bearing 9; the hanger 4 is provided with Several groups of static fixing devices 11, the static fixing devices 11 have at least one group, and each group of static fixing devices 11 includes two clamping devices 12, and the two clamping devices 12 are arranged oppositely, the clamping devices 12 includes a fitting plate 121, the side of the fitting plate 121 away from the electric telescopic rod 13 is provided with a rubber anti-skid pad 122, and the fitting plate 121 is arc-shaped, and one side of the fitting plate 121 is fixedly connected to the extension of the electric telescopic rod 13. At the end, the end of the electric telescopic rod 13 away from the laminating plate 121 is fixedly connected to the hanger 4; the inner wall of the kettle body 1 is evenly provided with strip-shaped protruding blocks 14 .

本盐酸伊立替康反应釜具有不易污染釜体内物质和混合效果好等特点。本反应釜通过电机6、转盘7和连接杆10带动釜体1摇晃实现混合的功能,不在釜体1内设置搅拌桨,从而不会污染釜体1内物质;釜体1的内壁上均匀设置有条状突出块14,在使用时随着釜体1的摇晃,内部的制备液在条状突出块14的作用下激荡更加激烈,提高了混合效果。The reaction kettle for irinotecan hydrochloride has the characteristics of not easily polluting the materials in the kettle and good mixing effect. The reaction kettle drives the kettle body 1 to shake through the motor 6, the turntable 7 and the connecting rod 10 to realize the mixing function, and does not set a stirring paddle in the kettle body 1, so as not to pollute the materials in the kettle body 1; There are strip-shaped protruding blocks 14, and with the shaking of the kettle body 1 during use, the internal preparation liquid is agitated more violently under the action of the strip-shaped protruding blocks 14, which improves the mixing effect.

尽管已经示出和描述了本实用新型的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本实用新型的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本实用新型的范围由所附权利要求及其等同物限定。Although the embodiments of the present invention have been shown and described, those skilled in the art can understand that various changes and modifications can be made to these embodiments without departing from the principle and spirit of the present invention , replacements and modifications, the scope of the present utility model is defined by the appended claims and their equivalents.

Claims (5)

1. a kind of irinotecan hydrochloride reactor, including kettle (1) and electric expansion bar (13), it is characterised in that:The kettle (1) bottom, which is fixedly connected with the top of the first montant (5), the kettle (1), is fixedly connected with the second montant (2), and described One end of the remote kettle (1) of two montants (2) is flexibly connected hanger (4) by the first oscillating bearing (3), and the hanger (4) is in Frame-like, and the bottom of hanger (4) is fixedly connected with motor (6), the rotor of the motor (6) and is fixedly connected with rotating disk (7), Vertical rod (8) is fixedly connected with the top of the rotating disk (7), the vertical rod (8) is flexibly connected the one of connecting rod (10) by bearing End, the one end of the connecting rod (10) away from vertical rod (8) is flexibly connected the first montant (5) by second joint bearing (9);It is described Some groups of standing fixing devices (11) are provided with hanger (4);Strip projecting block is evenly arranged with the inwall of the kettle (1) (14)。
2. a kind of irinotecan hydrochloride reactor according to claim 1, it is characterised in that:The standing fixing device (11) at least one group, and every group of standing fixing device (11) includes two clamping devices (12), and two clamping devices (12) It is oppositely arranged.
3. a kind of irinotecan hydrochloride reactor according to claim 2, it is characterised in that:Clamping device (12) bag Include jointing plate (121), the side of the jointing plate (121) is fixedly connected with the external part of electric expansion bar (13), it is described electronic to stretch The one end of contracting bar (13) away from jointing plate (121) is fixedly connected with hanger (4).
4. a kind of irinotecan hydrochloride reactor according to claim 3, it is characterised in that:The jointing plate (121) is remote Side from electric expansion bar (13) is provided with rubber antiskid pad (122), and jointing plate (121) is curved.
5. a kind of irinotecan hydrochloride reactor according to claim 1, it is characterised in that:The position of the vertical rod (8) Axle center away from rotating disk (7).
CN201720103692.1U 2017-01-24 2017-01-24 A kind of irinotecan hydrochloride reactor Expired - Fee Related CN206454651U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108273468A (en) * 2018-04-08 2018-07-13 合润科技有限公司 A kind of autoclave body producing polyalphaolefin polymerization reaction kettle
CN109865455A (en) * 2019-04-17 2019-06-11 焦作大学 A kind of Fast Mixing Equipment of two-component chemical reagent

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108273468A (en) * 2018-04-08 2018-07-13 合润科技有限公司 A kind of autoclave body producing polyalphaolefin polymerization reaction kettle
CN109865455A (en) * 2019-04-17 2019-06-11 焦作大学 A kind of Fast Mixing Equipment of two-component chemical reagent

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Granted publication date: 20170901

Termination date: 20210124