CN206381999U - Reactor for synthesizing chenodeoxycholic acid - Google Patents
Reactor for synthesizing chenodeoxycholic acid Download PDFInfo
- Publication number
- CN206381999U CN206381999U CN201720006836.1U CN201720006836U CN206381999U CN 206381999 U CN206381999 U CN 206381999U CN 201720006836 U CN201720006836 U CN 201720006836U CN 206381999 U CN206381999 U CN 206381999U
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- CN
- China
- Prior art keywords
- gear
- planetary
- rotating shaft
- sleeve pipe
- bearing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- RUDATBOHQWOJDD-BSWAIDMHSA-N chenodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-BSWAIDMHSA-N 0.000 title claims abstract description 13
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title claims abstract description 12
- 229960001091 chenodeoxycholic acid Drugs 0.000 title claims abstract description 12
- 230000002194 synthesizing effect Effects 0.000 title description 2
- 239000006247 magnetic powder Substances 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 7
- 239000002994 raw material Substances 0.000 abstract description 15
- 238000006243 chemical reaction Methods 0.000 abstract description 9
- 238000003756 stirring Methods 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 210000000941 bile Anatomy 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Landscapes
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
A kind of reactor for being used to synthesize chenodeoxycholic acid, including：Tank body, be arranged at the support of tank body upper end, be rotatablely installed the sleeve pipe in tank body vertically by bearing II, be installed on the dasher of its lower end, upper and lower side respectively by bearing III be rotatablely installed vertically in the rotating shaft in sleeve pipe, be installed on rotating shaft lower end its be located at dasher below anchor agitator, planetary gears and arrestment mechanism.When bile raw material addition reactor is started into reaction, planetary wheel carrier is rotated by the drive gear I of external gear I, realizes sleeve rotating, so that dasher is acted.And with the progress of reaction, material viscosity is uprised, it is rotated using external gear I by the drive shaft of gear I while this hour circle is rotated, so that rotating shaft driving anchor agitator action, the stirring requirement of raw material, can improve mixing effect, improve production efficiency again when can meet different viscosities.
Description
Technical field
The utility model is related to chemical machinery field, and in particular to a kind of reactor for being used to synthesize chenodeoxycholic acid.
Background technology
, it is necessary to will enter in the bile raw material extracted from chicken and duck courage addition reactor in synthesis CDCA acid production process
Row reaction, needs to use agitator to be stirred during the course of the reaction, and reactor agitator typically uses dasher or anchor
Producing axial rotational flow in one kind of formula agitator, anchor agitator whipping process, it is generally used for the higher raw material of viscosity, still
Its slow stirring efficiency of anchor agitator rotating speed is relatively low, and dasher can produce eddy flow axially and radially, but it is used for
During the higher raw material of viscosity, its mixing effect is deteriorated, because the concentration of raw material in chenodeoxycholic acid building-up process is by dilute retrogradation
, therefore the need for can not all well adapting to production using traditional dasher or anchor agitator.
The content of the invention
The utility model is stirred to overcome the shortcomings of that above technology changes there is provided one kind according to material concentration using difference
Device stirring is mixed to improve the reactor for being used to synthesize chenodeoxycholic acid of mixing uniformity and efficiency.
The technical scheme that the utility model overcomes its technical problem to be used is：
A kind of reactor for being used to synthesize chenodeoxycholic acid, including：Tank body, the support for being arranged at tank body upper end, by axle
The II vertical sleeve pipe being rotatablely installed in tank body, the dasher for being installed on its lower end, upper and lower side are held respectively by bearing
III it is vertical be rotatablely installed in the rotating shaft in sleeve pipe, be installed on rotating shaft lower end its be located at anchor agitator below dasher,
Planetary gears and arrestment mechanism, the motor output shaft of the motor are rotatablely installed on support vertically by bearing I, institute
State sun gear that planetary gears is coaxially disposed by gear ring, in gear ring and with gear ring and N number of turned respectively by wheel shaft
The dynamic planetary gear being installed on planetary wheel carrier is constituted, and the outer end of the gear ring is provided with external gear II, the endoporus of the gear ring
Internal gear is provided with, sun gear is fixed on motor output shaft, planetary wheel carrier is rotatablely installed in motor output shaft by bearing IV
On, N number of planetary gear is meshed with internal gear and sun gear respectively, and the upper end of the rotating shaft is provided with gear II, the gear
II is meshed with external gear II, and the upper end of sleeve pipe is provided with gear I, and the outer end of the planetary wheel carrier is provided with external gear I, described
Gear I is meshed with external gear I, the locked fixation in position of planetary wheel carrier during the arrestment mechanism work.
Above-mentioned arrestment mechanism includes the magnetic powder brake being installed on support and is installed on magnetic powder brake output shaft
Gear III, the outer end of the planetary wheel carrier is provided with external gear I, and gear gear III is meshed with external gear I.
In order to improve sealing, sealing ring is provided between above-mentioned sleeve pipe and rotating shaft and positioned at the outside of bearing III.
In order to further improve mixing effect, transverse slat is horizontally arranged between above-mentioned anchor agitator and rotating shaft.
The beneficial effects of the utility model are：When bile raw material addition reactor is started into reaction, gear ring has resistance, so
The N number of planetary gear of sun wheel drive revolves round the sun around gear ring internal gear, and planetary wheel carrier turns also by bearing IV around motor output shaft
Dynamic, planetary wheel carrier is rotated by the drive gear I of external gear I, realizes sleeve rotating, so that dasher is acted.Paddle is stirred
It makes the eddy flow of raw material generation axially and radially in reactor when mixing device rotation, so as to improve the uniformity and effect of stirring
Rate.And with the progress of reaction, material viscosity is uprised, now arrestment mechanism is locked by planetary wheel carrier, and planetary wheel carrier can not be free
Rotate, it drives N number of planetary gear to be rotated by wheel shaft relative to planetary wheel carrier when now sun gear is rotated, planetary gear driven gear ring
Rotate, it is rotated using external gear I by the drive shaft of gear I while ring gear against rotation, so that rotating shaft driving anchor formula stirring
Device is acted, due to the ring gear against rotation of now planetary gears, it is achieved that the switching of rotating ratio, the low-speed big of gear ring
The work of anchor agitator is may insure, the real-time switching of dasher and anchor agitator is realized, difference can be met
The stirring requirement of raw material, can improve mixing effect, improve production efficiency again during viscosity.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model；
Fig. 2 is planetary gear portion structure schematic diagram of the present utility model；
In figure, the rotating shaft of 1. tank body, 2. support, 3. motor, 4. bearing, I 5. motor output shaft, 6. sleeve pipe, 7. bearing II 8.
9. the gear ring 16. of 14. planetary gear of bearing III 10. sealing ring, 11. dasher, 12. anchor agitator, 13. transverse slat 15.
The external gear I 23. of 21. gear of planetary wheel carrier 17. bearing, IV 18. gear, I 19. gear, II 20. magnetic powder brake III 22.
The internal gear of 24. sun gear of wheel shaft, 25. external gear II 26..
Embodiment
Below in conjunction with the accompanying drawings 1, accompanying drawing 2 is described further to the utility model.
A kind of reactor for being used to synthesize chenodeoxycholic acid, including：Tank body 1, the support 2 for being arranged at the upper end of tank body 1, pass through
Sleeve pipe 6, the dasher 11 for being installed on the lower end of sleeve pipe 6, the upper and lower side that bearing II 7 is rotatablely installed in tank body 1 vertically are distinguished
By the way that bearing III 9 is rotatablely installed in the rotating shaft 8 in sleeve pipe 6 vertically, being installed on the lower end of rotating shaft 8, it is located under dasher 11
Anchor agitator 12, planetary gears and the arrestment mechanism of side, the motor output shaft 5 of motor 3 are turned vertically by bearing I 4
It is dynamic to be installed on support 2, the sun gear 24 that planetary gears is coaxially disposed by gear ring 15, in gear ring 15 and with gear ring 15
And N number of be rotatablely installed respectively by wheel shaft 23 is constituted in the planetary gear 14 on planetary wheel carrier 16, the outer end of gear ring 15 is provided with
Internal gear 26 is provided with external gear II 25, the endoporus of gear ring 15, sun gear 24 is fixed on motor output shaft 5, planetary wheel carrier
16 are rotatablely installed on motor output shaft 5 by bearing IV 17, N number of planetary gear 14 respectively with internal gear 26 and sun gear 24
It is meshed, the upper end of rotating shaft 8 is provided with gear II 19, and gear II 19 is meshed with external gear II 25, the upper end peace of sleeve pipe 6
Equipped with gear I 18, the outer end of planetary wheel carrier 16 is provided with external gear I 22, and gear I 18 is meshed with external gear I 22, braking
The locked fixation in position of planetary wheel carrier 16 when mechanism works.When bile raw material addition reactor is started into reaction, initial raw material
Viscosity is low, and now motor 3 is rotated, so that the driving sun gear 24 of motor output shaft 5 is rotated, due to the tooth on gear ring 15 and rotating shaft 8
II 19 are taken turns to be meshed and the rotating torque of anchor agitator 12 is big, therefore gear ring 15 has resistance, so sun gear 24 drives N number of row
Star gear 14 revolves round the sun around the internal gear 26 of gear ring 15, and planetary wheel carrier 16 surrounds 5 turns of motor output shaft also by bearing IV 17
Dynamic, planetary wheel carrier 16 is rotated by the drive gear I 18 of external gear I 22, realizes that sleeve pipe 6 rotates, so that dasher 11
Action.It makes the eddy flow of raw material generation axially and radially in reactor when dasher 11 is rotated, so as to improve stirring
Uniformity and efficiency.And with the progress of reaction, material viscosity is uprised, now arrestment mechanism is locked by planetary wheel carrier 16, OK
Star wheel frame 16 can not be rotated freely, and it drives N number of planetary gear 14 by wheel shaft 23 with respect to planet when now sun gear 24 is rotated
Wheel carrier 16 is rotated, and the driven gear ring 15 of planetary gear 14 is rotated, and it passes through gear I using external gear I 25 while gear ring 15 is rotated
18 drive shafts 8 are rotated, so that the driving anchor agitator 12 of rotating shaft 8 is acted, due to the gear ring 15 of now planetary gears
Rotate, it is achieved that the switching of rotating ratio, the low-speed big of gear ring 15 may insure the work of anchor agitator 12, realize
The real-time switching of dasher 11 and anchor agitator 12, when can meet different viscosities the stirring requirement of raw material, again may be used
To improve mixing effect, production efficiency is improved.
Arrestment mechanism can be following structure, and it includes the magnetic powder brake 20 being installed on support 2 and is installed on magnetic
Gear III 21 on the output shaft of powder brake 20, the outer end of planetary wheel carrier 16 is provided with external gear I 22, gear gear III 21
It is meshed with external gear I 22.When just starting reaction, the input current of magnetic powder brake 20 is 0, now magnetic powder brake 20
Resistance is not produced, the driving sun gear 24 of motor 3 is rotated, because gear ring 15 is meshed and anchor formula is stirred with the gear II 19 in rotating shaft 8
Mix the rotating torque of device 12 big, therefore gear ring 15 has resistance, so sun gear 24 drives N number of planetary gear 14 around the interior of gear ring 15
Gear 26 is revolved round the sun, and planetary wheel carrier 16 is rotated also by bearing IV 17 around motor output shaft 5, and planetary wheel carrier 16 passes through external gear I
22 drive gears I 18 are rotated, and realize that sleeve pipe 6 rotates, so that dasher 11 is acted, and when the electricity of magnetic powder brake 20
Stream increase, magnetic powder brake 20 produces resistive torque, and it is locked by planetary wheel carrier 16, and planetary wheel carrier 16 can not be rotated freely, this
When sun gear 24 it drives N number of planetary gear 14 to be rotated by wheel shaft 23 relative to planetary wheel carrier 16 when rotating, planetary gear 14 drives
Gear ring 15 is rotated, and it is rotated using external gear I 25 by the drive shaft 8 of gear I 18 while gear ring 15 is rotated, so that turning
The driving anchor agitator 12 of axle 8 is acted.
Further, between sleeve pipe 6 and rotating shaft 8 and the outside of bearing III 9 is provided with sealing ring 10, sealing ring 10
It can prevent in raw material and external dust sleeve pipe 6, so as to improve sealing.Between anchor agitator 12 and rotating shaft 8
Transverse slat 13 can be horizontally arranged with.When anchor agitator 12 is rotated, transverse slat 13 can make raw material produce axial rotational flow, so as to enter
One step improves mixing effect.
Claims (4)
1. a kind of reactor for being used to synthesize chenodeoxycholic acid, it is characterised in that including：Tank body（1）, be arranged at tank body（1）On
The support at end（2）, pass through bearing II（7）It is rotatablely installed vertically in tank body（1）In sleeve pipe（6）, be installed on sleeve pipe（6）Lower end
Dasher（11）, upper and lower side pass through bearing III respectively（9）It is rotatablely installed vertically in sleeve pipe（6）Interior rotating shaft（8）, be installed on
Rotating shaft（8）Lower end its be located at dasher（11）The anchor agitator of lower section（12）, planetary gears and arrestment mechanism,
Motor（3）Motor output shaft（5）Pass through bearing I（4）It is rotatablely installed vertically in support（2）On, the planetary gears by
Gear ring（15）, positioned at gear ring（15）Interior and and gear ring（15）The sun gear being coaxially disposed（24）And N number of pass through wheel shaft respectively
（23）It is rotatablely installed in planetary wheel carrier（16）On planetary gear（14）Constitute, the gear ring（15）Outer end be provided with external gear II
（25）, the gear ring（15）Endoporus in be provided with internal gear（26）, sun gear（24）It is fixed on motor output shaft（5）On, OK
Star wheel frame（16）Pass through bearing IV（17）It is rotatablely installed in motor output shaft（5）On, N number of planetary gear（14）Respectively with internal gear
（26）And sun gear（24）It is meshed, the rotating shaft（8）Upper end be provided with gear II（19）, the gear II（19）With it is outer
Gear II（25）It is meshed, sleeve pipe（6）Upper end gear I is installed（18）, the planetary wheel carrier（16）Outer end be provided with it is outer
Gear I（22）, the gear I（18）With external gear I（22）It is meshed, planetary wheel carrier during the arrestment mechanism work（16）Position
Put locked fixation.
2. the reactor according to claim 1 for being used to synthesize chenodeoxycholic acid, it is characterised in that：The arrestment mechanism bag
Include and be installed on support（2）On magnetic powder brake（20）And it is installed on magnetic powder brake（20）Gear III on output shaft
（21）, the planetary wheel carrier（16）Outer end be provided with external gear I（22）, gear gear III（21）With external gear I（22）Mutually nibble
Close.
3. the reactor according to claim 1 or 2 for being used to synthesize chenodeoxycholic acid, it is characterised in that：Described sleeve pipe（6）
With rotating shaft（8）Between and positioned at bearing III（9）Outside be provided with sealing ring（10）.
4. the reactor according to claim 3 for being used to synthesize chenodeoxycholic acid, it is characterised in that：The anchor agitator
（12）With rotating shaft（8）Between be horizontally arranged with transverse slat（13）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720006836.1U CN206381999U (en) | 2017-01-04 | 2017-01-04 | Reactor for synthesizing chenodeoxycholic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720006836.1U CN206381999U (en) | 2017-01-04 | 2017-01-04 | Reactor for synthesizing chenodeoxycholic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206381999U true CN206381999U (en) | 2017-08-08 |
Family
ID=59493228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720006836.1U Expired - Fee Related CN206381999U (en) | 2017-01-04 | 2017-01-04 | Reactor for synthesizing chenodeoxycholic acid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206381999U (en) |
Cited By (10)
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| CN107670530A (en) * | 2017-10-31 | 2018-02-09 | 青岛科技大学 | A kind of big resistance material automix device |
| CN107694408A (en) * | 2017-11-08 | 2018-02-16 | 青岛科技大学 | A kind of frame-type viscous material automatic mixed stirring device |
| CN107715724A (en) * | 2017-11-09 | 2018-02-23 | 海洋化工研究院有限公司 | A kind of adjustable planet gear type non-skid coating agitator of moment of torsion |
| CN107754685A (en) * | 2017-11-08 | 2018-03-06 | 青岛科技大学 | A kind of convertible self- poking arrangement of moveable moment of torsion |
| CN107983202A (en) * | 2018-01-06 | 2018-05-04 | 青岛科技大学 | A kind of stable type stickiness coating automix device |
| CN108007805A (en) * | 2017-11-30 | 2018-05-08 | 青岛科技大学 | A kind of moveable coating performance monitoring device of full-automatic |
| CN108126587A (en) * | 2018-01-31 | 2018-06-08 | 青岛科技大学 | The controllable paint vehicle stirring of torque and paint scraping device |
| CN108579638A (en) * | 2018-04-02 | 2018-09-28 | 泸州职业技术学院 | Reaction kettle |
| CN111001372A (en) * | 2019-11-21 | 2020-04-14 | 安徽科宝生物工程有限公司 | Reaction device for esterification of ursodeoxycholic acid and use method thereof |
| CN114177869A (en) * | 2021-12-16 | 2022-03-15 | 泸州职业技术学院 | An adjustable double stirring reactor |
-
2017
- 2017-01-04 CN CN201720006836.1U patent/CN206381999U/en not_active Expired - Fee Related
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107670530B (en) * | 2017-10-31 | 2021-08-06 | 青岛科技大学 | A large resistance material automatic mixing device |
| CN107670530A (en) * | 2017-10-31 | 2018-02-09 | 青岛科技大学 | A kind of big resistance material automix device |
| CN107694408A (en) * | 2017-11-08 | 2018-02-16 | 青岛科技大学 | A kind of frame-type viscous material automatic mixed stirring device |
| CN107754685A (en) * | 2017-11-08 | 2018-03-06 | 青岛科技大学 | A kind of convertible self- poking arrangement of moveable moment of torsion |
| CN107694408B (en) * | 2017-11-08 | 2023-04-07 | 青岛科技大学 | Frame-type stickness material automatic mixing agitating unit |
| CN107715724A (en) * | 2017-11-09 | 2018-02-23 | 海洋化工研究院有限公司 | A kind of adjustable planet gear type non-skid coating agitator of moment of torsion |
| CN107715724B (en) * | 2017-11-09 | 2023-06-27 | 海洋化工研究院有限公司 | Planetary wheel type anti-slip paint stirrer with adjustable torque |
| CN108007805A (en) * | 2017-11-30 | 2018-05-08 | 青岛科技大学 | A kind of moveable coating performance monitoring device of full-automatic |
| CN108007805B (en) * | 2017-11-30 | 2019-12-06 | 青岛科技大学 | A fully automatic mobile coating performance monitoring device |
| CN107983202A (en) * | 2018-01-06 | 2018-05-04 | 青岛科技大学 | A kind of stable type stickiness coating automix device |
| CN108126587A (en) * | 2018-01-31 | 2018-06-08 | 青岛科技大学 | The controllable paint vehicle stirring of torque and paint scraping device |
| CN108126587B (en) * | 2018-01-31 | 2024-03-15 | 青岛科技大学 | Paint stirring and scraping device with controllable torque |
| CN108579638A (en) * | 2018-04-02 | 2018-09-28 | 泸州职业技术学院 | Reaction kettle |
| CN111001372A (en) * | 2019-11-21 | 2020-04-14 | 安徽科宝生物工程有限公司 | Reaction device for esterification of ursodeoxycholic acid and use method thereof |
| CN114177869A (en) * | 2021-12-16 | 2022-03-15 | 泸州职业技术学院 | An adjustable double stirring reactor |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170808 Termination date: 20220104 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |