CN206357665U - A kind of biological 3D printing printhead - Google Patents
A kind of biological 3D printing printhead Download PDFInfo
- Publication number
- CN206357665U CN206357665U CN201621434082.1U CN201621434082U CN206357665U CN 206357665 U CN206357665 U CN 206357665U CN 201621434082 U CN201621434082 U CN 201621434082U CN 206357665 U CN206357665 U CN 206357665U
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- CN
- China
- Prior art keywords
- closure
- biological
- hybrid chamber
- agitator
- material hybrid
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000010146 3D printing Methods 0.000 title claims abstract description 21
- 239000000463 material Substances 0.000 claims abstract description 50
- 238000003756 stirring Methods 0.000 claims abstract description 16
- 238000006243 chemical reaction Methods 0.000 claims description 16
- 238000010438 heat treatment Methods 0.000 claims description 15
- 210000004907 gland Anatomy 0.000 claims description 9
- 239000012530 fluid Substances 0.000 claims description 5
- 229910001220 stainless steel Inorganic materials 0.000 claims description 5
- 239000010935 stainless steel Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 3
- 230000001360 synchronised effect Effects 0.000 abstract description 3
- 230000006872 improvement Effects 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 238000004132 cross linking Methods 0.000 description 4
- 238000001125 extrusion Methods 0.000 description 4
- 239000000017 hydrogel Substances 0.000 description 4
- 238000007639 printing Methods 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000006452 multicomponent reaction Methods 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Abstract
The utility model is related to a kind of biological 3D printing printhead, including the material hybrid chamber on 3D printer transfer arm, and the inlet for being fed to material hybrid chamber is provided with material hybrid chamber；Drainage conduit is provided with material hybrid chamber, agitator and removal device are provided with material hybrid chamber, wherein agitator is rotary agitator, stir raised on the rotary shaft including rotary shaft and setting, after material in material hybrid chamber is mixed via the Stirring of agitator, by the driving of removal device, extruded from drainage conduit, the utility model is realized and the mixing of biosimulation material, the synchronous of hardening is carried out by a stirring cavity for carrying mixed function.
Description
Technical field
The utility model, which is related to one kind, is used for biosimulation printing device field, in particular belongs to a kind of biological 3D printing and uses
Printhead.
Background technology
, it is necessary to be pressurizeed to hydrogel or hydrogel-stem cell compound, heat behaviour during traditional biological 3D printing
Make, to reduce viscosity of material, realize extrusion, i.e. physical phase transition molding techniques.The utility model to solve this problem, by water-setting
Glue chemical polymerization is transferred in biological 3D printing printhead, and original position is mixed and induces reaction so that material is in stream
Cross during extruder head in low viscosity state, utilize the holdup time in extruder head to control to chemically react so that material leaves crowded
Lift one's head discharge gate when reach enough high viscositys, keep the shape of 3D printing design.The biological 3D printing of this patent requirement, which is used, beats
Head is printed to design based on biological enzyme cross-linking system.In the case of oxidant presence, biology enzyme can will carry phenol functional group
Macromolecule hydrogel monomer polymerization, so as to realize the chemical polymerization phase transformation of hydrogel material.On this basis, it is possible to achieve its
The operation of his multicomponent reaction cross-linking system.
Utility model content
The technical problems to be solved in the utility model is：Overcoming technical problem of the prior art, there is provided a kind of biological 3D
Printing printhead.
The utility model solves the technical scheme that its technical problem used：
A kind of biological 3D printing printhead, including the material hybrid chamber on 3D printer transfer arm, in material
The inlet for being fed to material hybrid chamber is provided with hybrid chamber；Drainage conduit is provided with the material hybrid chamber,
It is provided with agitator and removal device in material hybrid chamber, wherein agitator is rotary agitator, including rotary shaft and is arranged on
Stir raised in rotary shaft, after the material in material hybrid chamber is via the Stirring mixing of agitator, pass through removal device
Driving, is extruded from drainage conduit.
As further improvement of the utility model, the removal device is structure as a whole with agitator, and the agitator is
Spiral agitator, the stirring projection includes setting spiral prominence playing piece on the rotary shaft, and the one end part of rotary shaft is in material
Expect the drainage conduit link position of hybrid chamber, the material in material hybrid chamber is mixed and from discharge under the pushing of spiral prominence playing piece
Pipe is discharged.
As further improvement of the utility model, the material hybrid chamber includes a closure,
As further improvement of the utility model, the inlet includes some turns being arranged on closure wall
Seat is changed, the conversion seat runs through closure wall, a joint for being used for connecting pipe joint is provided with conversion seat and is consolidated
Determine hole.
As further improvement of the utility model, the closure is closing tubbiness, and wherein drainage conduit is connected to envelope
Axial one end of shell is closed, the axial other end of closure is provided with an opening, one is provided with over said opening
Closed end cap, rotates connection between the rotary shaft and closed end cap.
As further improvement of the utility model, an annular flange is provided with the edge of the closed end cap, is revolved
Rotating shaft is fixed to closed end cap by a driving stepper motor, the motor housing of stepper motor by foregoing annular flange
On.
As further improvement of the utility model, a heating jacket is additionally provided with the outer wall of closure, is being added
An annular heating cavities are provided with thermal jacket, the heating cavities are connected with circulation hot-fluid by transfer tube and pipeline
Septate heat transfer is carried out between material inside body, thermal fluid circulation and closure.
As further improvement of the utility model, the drainage conduit is screw needle tubular construction, it include one it is hollow
Discharge needle and the gland for being fixed on discharge needle end part, a connecting seat, the company are provided with the end of the closure
It is connected through a screw thread between joint chair and gland.
As further improvement of the utility model, the connecting seat includes an adapter sleeve, in the end of closure
A connection ring is fixed with, is connected through a screw thread between connection ring and adapter sleeve, in being fixedly arranged in the middle of for fixing for adapter sleeve
The connecting tube of gland.
As further improvement of the utility model, the closure is made of stainless steel.
The beneficial effects of the utility model are：
1st, the utility model is realized to the mixing of biosimulation material, firmly by a stirring cavity for carrying mixed function
The synchronous progress of change.Avoid the heating in classic screw extrusion, the potential impact that pressure process is caused to stem cell, mix
The chemical reaction occurred while conjunction, can reach that exit completes polymerisation, so as to avoid the height in extruder head in fluid
Pressure, hot environment, realize chemical reaction plastotype.
2nd, the agitator and removal device of integrative-structure optimize structure, compared to air pressure material extrusion, the method for stirring rod spice
For, the pressure of closure is relatively low in this structure, it is not easy to leak；Compared to compressible gas, the row of this structure
Expect that speed can be by controlling the speed of rotation of spiral prominence playing piece to be controlled, controllability is higher；And this structure can be by
It is completely exhausted out after material stirring, is not easy the presence of stirring dead angle compared to poking bar.
3rd, conversion seat can facilitate the screw-type connection of all kinds of joints, be connect compared to being installed additional on closure for pipeline
The screwed hole of head dismounting, conversion seat can realize the switching of pipe joint, reduce the utilization rate of closure upper screwed hole, improve
The life-span of closure.
4th, rotating seat undertakes screw rod and fixed and sealing task, can stablize screw rod and rotate the vibrations caused, and isolate motor
Part and material bin, realize the requirement of environment sterileization in shell.
5th, the closure of this structure is the end cover structure that can be turned on and off, and greatly facilitates and closure is torn open
Unload the cleaning with internal part.
6th, the flange arrangement being arranged on end cap facilitates the stable fixation of motor, it is ensured that motor and closure it is same
Step connection, shake when will not be rotated because of motor causes rotary shaft to occur opposing compression with closure and cause rotary shaft
Deformation, so as to reduce the jitter rate of printhead during printing, improves print quality.
7th, the heating jacket of external is compared to built-in heat pipes heat, and heat exchange efficiency is high, and will not be outer to closing
The band of shell inner space and closure influences.
8th, this printhead uses the discharging structure of medical needle tube type, and the connected mode of screw thread is easy to disassemble and changes.
9th, the utility model is transferred by adapter sleeve, compared to being directly connected to for needle tubing, and this structure can expand envelope
The opening size of outer casing end is closed, is easy to the cleaning of closure；And exchanging structure can be improved outside closing compared to direct-connected
The life-span of shell.
Brief description of the drawings
The utility model is further illustrated with reference to the accompanying drawings and examples.
Fig. 1 is the diagrammatic cross-section of printhead；
Fig. 2 is the partial enlarged drawing at A in Fig. 1；
Fig. 3 is the assembling schematic diagram of printhead motor.
In figure：1st, closure；2nd, rotary shaft；3rd, threaded bosses；4th, closed end cap；5th, rotating seat；6th, conversion seat；7th, even
Connect ring；8th, adapter sleeve；9th, connecting tube；10th, gland；11st, discharge needle；12nd, heating jacket；13rd, water inlet；14th, motor housing；
15th, shaft coupling；16th, stepper motor.
Embodiment
The utility model is described in further detail presently in connection with accompanying drawing.These accompanying drawings are simplified schematic diagram,
Only illustrate basic structure of the present utility model in a schematic way, therefore it only shows the composition relevant with the utility model.
As shown in figure 1, the utility model is a kind of biological 3D printing printhead, its main body is a cylindric closing
Shell, the discharge chamber of a gradually-reducing shape is provided with axial one end of closure, is set on the axial other end of closure
It is equipped with a closed end cap；A material hybrid chamber is constituted in closure, is realized to printing the mixing of material, and pass through discharge
Chamber is discharged, and closed end cap can be fixed on closure using flange or helicitic texture.
In order to realize the purpose of stirring, the screw mixing of stirring and discharge functions is provided with closure
Device, its main body rotates the rotary shaft being connected including one between closed end cap, and a rotation is fixedly arranged in the middle of in closed end cap
Seat, rotating seat is rotated with rotary shaft by sealed bearings and is connected, and rotary shaft is synchronous with closure fixed, and wherein one end extends
To the necking end of discharge chamber, the threaded bosses of sequential like are provided with the rotary shaft, the radius of fillet of its threaded bosses can root
Set according to specific operating mode, its specific operating mode is mainly the viscosity of material to be referred to, can be by subtracting for the larger material of viscosity
Minor thread radius is to reduce its friction area；Stirring mixing then occurs by the rotation of threaded bosses for material, and in screw thread
Discharged under pushing by discharge chamber.The speed that the speed of screw rod rotation is reacted by hydrogel polymeric determines that high reaction rate printing is needed
The short holdup time is wanted, i.e. higher baseline speed, vice versa.
In order to control quality, in 20 Pa once, extruded stock shear modulus G ' can reach general charging shear modulus G '
200-10000 Pa。
As shown in Fig. 2 coaxial be fixed with a connection ring, connection ring has been connected through a screw thread one on the end of discharge chamber
Individual connecting seat, connecting seat includes the tubular adapter sleeve of an one end open, and the inwall of adapter sleeve is fixedly connected with connection ring；Simultaneously
It is provided with the middle part of the blind end of adapter sleeve in a connecting tube, connecting tube and has been connected through a screw thread medical stainless steel needle tubing；Its
The adapter sleeve profile of middle connecting seat can be set to straight tube or bending tubular according to different operating modes；
Medical stainless steel needle tubing includes hollow discharge needle and is fixed on the gland of discharge needle end part, gland with
It is connected through a screw thread between connecting tube.
As shown in figure 1, being further fixed on a heating jacket in the outside of closure, one is provided with heating jacket
The heating cavities of annular, a water inlet and a discharge outlet are provided with heating jacket outer wall, and are completely cut off with materials inside cabin,
Ensure the gnotobasis in materials inside cabin.Water inlet and discharge outlet are connected to a water by a transfer tube and heated on bucket, lead to
Pump overdrive so that hot water realizes the heat exchange between closure in heating jacket internal circulation flow.
Some inlets are additionally provided with the outer wall of closure, the position of inlet and bore are according to according to specific material
Quantity and characteristic be configured, inlet includes some conversion seats being arranged on closure wall, and the conversion seat passes through
Chuanfeng closes shell wall, and one is provided with conversion seat is used for the joint fixing hole of connecting pipe joint；The feed of material is then
It is fed, easily can be then dismantled during dismounting by rotating by the connecting tube being connected on foregoing adapter, this
Can be with the snap joint of more prefabricated such as pagoda joint etc, to realize the fast assembling-disassembling of pipeline on external conversion seat.
In order to ensure certain gnotobasis, the part such as closure, closed end cap, spiral agitator is using stainless
Steel is made.
Such as Fig. 1 and Fig. 3, be additionally provided with an annular flange in closed end cap periphery, rotary shaft by a shaft coupling with
Stepper motor is connected, and the motor housing of stepper motor is fixed on closed end cap by foregoing annular flange；In order to drop
Low vibration can be attached using Hooks coupling universal coupling.
When specifically used：With superoxide dismutase（HRP）/ hydrogen peroxide（H2O2）Exemplified by cross-linking system, wherein peroxidating
Thing mutase（HRP）Inlet be located at the top of closure close to closed end cap position, and hydrogen peroxide（H2O2）Inlet
Then it is located at closure bottom close to discharge chamber position；Both are squeezed into closed cavity by certain material extrusion pump, and are passed through
Spiral agitator is stirred so that superoxide dismutase（HRP）And hydrogen peroxide（H2O2）Occur in discharge empty cavity position mixed
Close, while being discharged via discharge needle, realize foregoing two raw material crosslinking condense, its setting time by discharge velocity control,
Specific governing factor includes screw rod rotary speed, flight pitch, length of discharge needle etc.；The intensity of gel can pass through feed
The rotating speed of proportioning and same control rotary shaft, is controlled.
Using it is above-mentioned according to desirable embodiment of the present utility model as enlightenment, pass through above-mentioned description, related work people
Member can carry out various changes and amendments in the range of without departing from this utility model technological thought completely.This reality
The content on specification is not limited to new technical scope, it is necessary to its technology is determined according to right
Property scope.
Claims (10)
1. a kind of biological 3D printing printhead, it is characterized in that：Including the material hybrid chamber on 3D printer transfer arm,
The inlet for being fed to material hybrid chamber is provided with material hybrid chamber；Discharge is provided with the material hybrid chamber
Pipe, is provided with agitator and removal device in material hybrid chamber, and wherein agitator is rotary agitator, including rotary shaft and sets
Put and stir raised on the rotary shaft, after the material in material hybrid chamber is via the Stirring mixing of agitator, pass through discharge
The driving of device, is extruded from drainage conduit.
2. a kind of biological 3D printing printhead as claimed in claim 1, it is characterized in that：The removal device is one with agitator
Body structure, the agitator is spiral agitator, and the stirring projection includes setting spiral prominence playing piece on the rotary shaft, rotation
The one end part of rotating shaft is in material the pushing away in spiral prominence playing piece in the drainage conduit link position of material hybrid chamber, material hybrid chamber
Force down, mix and discharged from drainage conduit.
3. a kind of biological 3D printing printhead as claimed in claim 1, it is characterized in that：The material hybrid chamber includes one
Closure.
4. a kind of biological 3D printing printhead as claimed in claim 3, it is characterized in that：The inlet includes some set
Conversion seat on closure wall, the conversion seat runs through closure wall, and one is provided with conversion seat is used for
The joint fixing hole of connecting pipe joint.
5. a kind of biological 3D printing printhead as claimed in claim 3, it is characterized in that：The closure is closed vat
Shape, wherein drainage conduit are connected to axial one end of closure, and the axial other end of closure is provided with an opening,
A closed end cap is provided with the opening, connection is rotated between the rotary shaft and closed end cap.
6. a kind of biological 3D printing printhead as claimed in claim 5, it is characterized in that：Set at the edge of the closed end cap
An annular flange is equipped with, rotary shaft passes through foregoing annular by a driving stepper motor, the motor housing of stepper motor
Flange is fixed on closed end cap.
7. a kind of biological 3D printing printhead as claimed in claim 3, it is characterized in that：Also set up in the outer wall of closure
Have a heating jacket, be provided with an annular heating cavities in heating jacket, the heating cavities by transfer tube and
Pipeline is connected between the material inside thermal fluid circulation, thermal fluid circulation and closure and carries out septate heat transfer.
8. a kind of biological 3D printing printhead as claimed in claim 3, it is characterized in that：The drainage conduit is screw thread needle tubing knot
Structure, it includes a hollow discharge needle and is fixed on the gland of discharge needle end part, is set in the end of the closure
There is a connecting seat, be connected through a screw thread between the connecting seat and gland.
9. a kind of biological 3D printing printhead as claimed in claim 8, it is characterized in that：The connecting seat includes a connection
Set, a connection ring is fixed with the end of closure, is connected through a screw thread between connection ring and adapter sleeve, in adapter sleeve
It is fixedly arranged in the middle of the connecting tube for fixing gland.
10. a kind of biological 3D printing printhead as claimed in claim 3, it is characterized in that：The closure is using stainless
Steel is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621434082.1U CN206357665U (en) | 2016-12-26 | 2016-12-26 | A kind of biological 3D printing printhead |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621434082.1U CN206357665U (en) | 2016-12-26 | 2016-12-26 | A kind of biological 3D printing printhead |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206357665U true CN206357665U (en) | 2017-07-28 |
Family
ID=59375911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621434082.1U Active CN206357665U (en) | 2016-12-26 | 2016-12-26 | A kind of biological 3D printing printhead |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206357665U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106626424A (en) * | 2016-12-26 | 2017-05-10 | 常州清大智造科技有限公司 | Printing head for biologic 3D printing |
| CN110948850A (en) * | 2019-12-22 | 2020-04-03 | 安徽科元三维技术有限公司 | A feeding device for a small metal mold 3D printer |
| CN112440466A (en) * | 2019-08-15 | 2021-03-05 | 中国科学院化学研究所 | Rapid forming device for ultrahigh molecular weight polymer |
-
2016
- 2016-12-26 CN CN201621434082.1U patent/CN206357665U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106626424A (en) * | 2016-12-26 | 2017-05-10 | 常州清大智造科技有限公司 | Printing head for biologic 3D printing |
| CN112440466A (en) * | 2019-08-15 | 2021-03-05 | 中国科学院化学研究所 | Rapid forming device for ultrahigh molecular weight polymer |
| CN110948850A (en) * | 2019-12-22 | 2020-04-03 | 安徽科元三维技术有限公司 | A feeding device for a small metal mold 3D printer |
| CN110948850B (en) * | 2019-12-22 | 2022-03-22 | 安徽科元三维技术有限公司 | A feeding device for a small metal mold 3D printer |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240521 Address after: Room B114, Zhongguancun Biomedical Park, No. 5 Kaifeng Road, Haidian District, Beijing, 100085 Patentee after: SUNP (BEIJING) BIOTECH CO.,LTD. Country or region after: China Address before: 213134 Entrepreneurship Center A324, Building 2, Science and Technology Park, Xinbei District, Changzhou City, Jiangsu Province Patentee before: CHANGZHOU QINGDA INTELLIGENT MANUFACTURING TECHNOLOGY CO.,LTD. Country or region before: China |