CN205603574U - Fermentation tank - Google Patents

Abstract

The utility model provides a fermentation tank, which includes a tank body, on which a motor is connected to a stirring shaft arranged in the tank body, and also includes: a spiral stirring unit, including a fixed arm and a spiral belt, the fixed The arm is fixedly arranged on the stirring shaft, and one end of the fixed arm away from the stirring shaft is fixed with one of the spiral bands; the stirring paddle unit is arranged on the stirring shaft; the stirring paddle unit is arranged on the stirring shaft; The spiral stirring unit is arranged on the shaft section of the stirring shaft close to the bottom of the fermenter, and the stirring paddle unit is arranged above the spiral stirring unit. The utility model improves the fermentation stirring efficiency, improves the oxygen utilization rate, and increases the dissolved oxygen concentration of the fermented liquid, so as to ensure the oxygen demand of microorganisms, increase the yield of microorganisms and ensure the quality of microorganisms.

Description

Fermenter

technical field

The utility model relates to a fermentation device, in particular to a pharmaceutical fermentation tank.

Background technique

At present, fermentation tanks are widely used in the pharmaceutical production process to ferment microorganisms. Microorganisms obtain most of the organic components in pharmaceuticals through fermentation, such as antibiotics, amino acids, organic acids, vitamins and other organic substances. When the microorganisms are fermenting in the fermenter, they need to be stirred, and the stirring can make the air mix with the fermentation liquid, so that oxygen can be dissolved in the fermentation liquid, so as to supply the growth and reproduction of the microorganisms. The existing pharmaceutical fermenter is usually provided with a stirring paddle, which is covered with several paddle blades, and the stirring paddle is connected with the output shaft of the driving device. When the driving device drives the stirring paddle to rotate, the paddles revolve The axis of the machine rotates to stir the fermentation broth. However, the current pharmaceutical fermenter has the disadvantage of low stirring efficiency.

The Chinese utility model patent with the application number of 201320860020.7 discloses a fermenter, which includes a tank body and a coiled pipe in the tank. The mixer is a paddle agitator, and the agitators on other layers are arrow blade agitators, and the inner wall of the tank at the lower part of the coil is provided with a baffle. When the above-mentioned fermenter is fermented, the fermented liquid is centered on the stirring paddle to form a vortex, so as to achieve the purpose of stirring. However, when the number of paddles is fixed, the size of the paddles is limited by the size of the drive shaft. The torque and shape should not be too large, and if the paddle only rotates around the axis of the stirring paddle, the stirring range will be relatively reduced, and the fermentation liquid far away from the stirring paddle axis cannot be fully stirred, the stirring efficiency is low, and the concentration of dissolved oxygen in the fermentation liquid The oxygen demand of microorganisms cannot be guaranteed, the fermentation efficiency is low, and the fermentation effect is not good.

In order to overcome the above problems, the Chinese utility model patent application number 201420204378.9 discloses a highly efficient stirring pharmaceutical fermenter, including a body, the body includes a tank body, a stirring device and a driving device all arranged on the tank body, the The stirring device includes a planetary reduction mechanism, a main stirring paddle and several auxiliary stirring paddles. The planetary reduction mechanism includes a ring gear, a sun gear and several planetary gears. The ring gear is fixed in the tank and is set corresponding to the top of the tank. The gear is arranged in the ring gear and meshes with the ring gear. The sun gear and the ring gear are arranged coaxially and meshed with each planetary gear. The main stirring paddle is installed on the sun gear and connected with the driving device. The stirring paddle is mounted on the planetary gear. Although the stirring efficiency of the fermenter provided by the utility model has been improved to a certain extent, the structure is very complicated, and the radial dimension of the fermenter needs to be large in order to be able to accommodate the planetary reduction mechanism, the main stirring paddle and several auxiliary stirring paddles, resulting in fermentation The production cost of the tank is high, and the space required for placing the fermentation tank is large.

In view of this, the utility model is proposed.

Utility model content

The technical problem to be solved by the utility model is to overcome the deficiencies of the prior art and provide a fermenter to solve the problem of low stirring efficiency of the existing fermenter, low concentration of dissolved oxygen in the fermentation liquid, inability to meet the oxygen demand of microorganisms, and low fermentation efficiency Problems, at the same time, overcome the problems of complex structure and high cost of highly efficient stirring fermenter.

In order to solve the problems of the technologies described above, the basic idea of the technical solution adopted by the utility model is:

A fermenter comprising:

The tank body is provided with a motor connected to a stirring shaft arranged in the tank body,

A spiral stirring unit, comprising a fixed arm and a spiral belt, the fixed arm is fixedly arranged on the stirring shaft, and one end of the fixed arm away from the stirring shaft is fixed with one spiral belt;

a stirring paddle unit, the stirring paddle unit is arranged on the stirring shaft;

The spiral stirring unit is arranged on the shaft section of the stirring shaft close to the bottom of the fermenter, and the stirring paddle unit is arranged above the spiral stirring unit.

It is not only the existing stirring paddle that stirs the fermentation liquid in the fermenter, but also a spiral stirring unit is arranged under the stirring paddle unit, so that a continuous circulating stirring flow is formed during the stirring process, the stirring is more uniform, and the stirring efficiency is higher. Allow oxygen to mix more fully with the fermentation broth.

Wherein, the spiral stirring unit includes a plurality of fixed arms, the fixed arms are arranged on the stirring shaft, the fixed arms are perpendicular to the axis of the stirring shaft, and all the fixed arms are arranged along the axial direction of the stirring shaft. distributed in a spiral shape.

Wherein, the helical belt includes a first helical surface and a second helical surface, and the fixing arm is fixed on the first helical surface.

Wherein, the helical belt is sequentially connected from the bottom of the fermenter to the top of the fermenter to form a helical stirring belt, and the helical stirring belt takes the axis of the stirring shaft as the center line of rotation and is in a spiral shape.

The helical belt and the fixed arm are combined and distributed in a helical shape along the axial direction of the stirring shaft in turn to form a helical stirring unit, which acts like a helical stirring blade to continuously push the fermentation liquid at the bottom and middle of the fermenter upwards. The air in the middle is mixed with the fermentation liquid, and the oxygen dissolves in the fermentation liquid, and is pushed up along with the fermentation liquid, so that the oxygen is fully mixed with the fermentation liquid in the fermenter.

Wherein, the stirring paddle unit includes a plurality of stirring paddles, and the stirring paddles of the stirring paddles are axial flow paddles or arrow-shaped paddles.

Wherein, a plurality of stirring blades are equidistantly distributed along the stirring shaft.

Wherein, the distance between any two connected stirring blades is equal to the pitch of the spiral stirring belt.

The fermented liquid mixed with oxygen is continuously pushed upwards from the bottom of the fermenter by the spiral stirring unit. When it reaches the position of the stirring paddle, the stirring paddle further stirs the fermented liquid, and pushes the fermented liquid upward and toward the tank along the radial direction of the fermenter. The direction of the internal wall moves, so that the middle and upper parts of the fermenter and the fermented liquid away from the stirring shaft are fully stirred, so that the oxygen and the fermented liquid in the fermenter are further fully mixed.

Wherein, a defoaming unit is also included, and the defoaming unit is arranged on the stirring shaft and above the stirring paddle unit.

Wherein, the defoaming unit includes at least one second fixed arm, the second fixed arm is arranged on the stirring shaft, and the plane where the second fixed arm is located is perpendicular to the stirring shaft.

Wherein, one end of the second fixed arm away from the stirring shaft is provided with a stirring rod along the axial direction of the stirring shaft, one end of the stirring rod is fixedly connected with the second fixed arm, and the other end of the stirring rod Point to the bottom of the fermenter.

The microorganisms in the fermentation tank will produce carbon dioxide and form bubbles during the fermentation process. The foam will float on the top of the liquid surface of the fermentation tank. Microorganisms respire and metabolize, while avoiding foam contamination of the fermenter.

After adopting the above technical solution, the utility model has the following beneficial effects compared with the prior art:

The utility model improves the stirring device of the existing fermenter. The stirring shaft is provided with a spiral stirring unit and a stirring paddle unit. Above the helical stirring unit. The fermented liquid mixed with oxygen is continuously pushed upwards from the bottom of the fermenter by the spiral stirring unit. When it reaches the position of the stirring paddle, the stirring paddle further stirs the fermented liquid, and pushes the fermented liquid upward and toward the tank along the radial direction of the fermenter. The direction of the inner wall moves, and due to the gravity of the fermentation liquid itself, the fermentation liquid falls along the inner wall of the fermenter to the bottom of the fermenter, and the spiral stirring unit continuously pushes the fermentation liquid in the bottom and middle of the fermenter upwards, so that the fermenter The fermentation liquid inside forms a circular stirring from the bottom along the stirring axis, then moves along the radial direction of the fermenter to the inner wall of the fermenter, then falls to the bottom of the fermenter along the inner wall of the fermenter, and then upwards from the bottom. The above-mentioned improvement to the existing fermenter improves the stirring efficiency of the fermenter, increases the dissolved oxygen concentration of the fermented liquid, satisfies the oxygen demand of microorganisms, and improves the fermentation efficiency. The problem of high cost.

Below in conjunction with accompanying drawing, the specific embodiment of the present utility model is described in further detail.

Description of drawings

Fig. 1 is the structural representation of the utility model fermentation tank;

Fig. 2 is the structural representation of the utility model spiral belt;

Fig. 3 is the structural representation of the utility model defoaming unit;

In the figure: tank body 1, motor 2, stirring shaft 3, spiral stirring unit 4, fixed arm 41, spiral belt 42, first spiral surface 421, second spiral surface 422, stirring paddle unit 5, stirring paddle 51, stirring paddle Leaf 52 , defoaming unit 6 , second fixed arm 61 , stirring rod 62 .

detailed description

In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. The following embodiments are used for illustration The utility model, but not used to limit the scope of the utility model.

Figure 1 is a schematic diagram of a preferred embodiment of the present invention. As shown in the figure, a motor 2 is provided on the upper end of the tank body 1. The motor 2 is connected to a stirring shaft 3 arranged in the tank body 1. The motor 2 drives the stirring shaft 3 to rotate. The stirring shaft 3 can be multi-section, and each joint are connected by couplings (not shown). The stirring shaft 3 is placed vertically along the axial direction of the fermenter. The stirring shaft 3 is provided with a spiral stirring unit 4, the spiral stirring unit 4 includes a fixed arm 41 and a spiral belt 42, the stirring shaft 3 is also provided with a stirring paddle unit 5, and the spiral stirring unit 4 is arranged on the stirring shaft 3 near the fermenter On the shaft section at the bottom, the stirring paddle unit 5 is arranged above the spiral stirring unit 4 . The fixed arm 41 in the spiral stirring unit 4 is fixedly arranged on the stirring shaft 3 , and one end of the fixed arm 41 away from the stirring shaft 3 is fixed with a spiral belt 42 . As can be seen from FIG. 1 , the stirring shaft 3 is provided with a spiral stirring unit 4 and a stirring paddle unit 5 in sequence along the bottom of the fermenter to the top of the fermenter. The bottom of the fermentation tank is provided with a ventilation pipe (not shown). When the fermentation tank is working, the air compressor will input compressed air into the fermentation tank through the ventilation pipe. During the stirring process, a continuous circulating stirring flow is formed, the stirring is more uniform, the stirring efficiency is higher, and the oxygen and the fermentation liquid are more fully mixed.

Embodiment one

As shown in Figures 1 and 2, the spiral stirring unit 4 described in the present embodiment includes a plurality of fixed arms 41, one end of the fixed arm 41 is arranged on the stirring shaft 3, the fixed arm 41 is perpendicular to the axis of the stirring shaft 3, The fixed arms 41 are staggeredly arranged on the stirring shaft 3, and the fixed arms 41 are arranged in a spiral shape along the axial direction of the stirring shaft 3 from the end of the stirring shaft 3 near the bottom of the fermenter to the end of the stirring shaft 3 near the top of the fermenter. One end of each fixed arm away from the stirring shaft 3 is fixed with a helical band 42, wherein each helical band 42 includes a first helical surface 421 and a second helical surface 422, that is, the upper and lower sides of the helical band, wherein The first helical surface 421 faces the top of the fermenter, and the second helical surface 422 faces the bottom of the fermenter.

One end of the fixed arm away from the stirring shaft 3 is fixedly connected to the first helical surface 421 on the spiral belt 42, or can be fixedly connected by a threaded fastener, and the end of the fixed arm away from the stirring shaft 3 can be set to a flat shape, and set There are through holes, and the first helical surface 421 on the helical belt 42 can be provided with a screw hole, which is convenient for the fixed connection of the fixed arm and the helical belt, so as to ensure that the fixed arm and the helical belt are always fixedly connected during the fermentation stirring process, and then the connection between the two There will be no relative movement or rotation of the helical belt around the fixed arm.

Further, all the helical bands 42 are sequentially connected from the bottom of the fermenter to the top of the fermenter, specifically, the first helical surfaces 421 of all the helical bands 42 are sequentially connected, and the second helical surfaces 422 of all the helical bands 42 are sequentially connected, All the helical bands form a helical stirring band, and the helical stirring band takes the axis of the stirring shaft 3 as the center line of rotation to form a helical shape.

Finally, the structure of the spiral stirring unit 4 is similar to a spiral stirring blade, which continuously pushes the fermented liquid in the bottom and middle of the fermenter upwards and stirs the fermented liquid. is pushed upwards so that the oxygen is thoroughly mixed with the fermentation broth in the bottom, middle and upper parts of the fermenter.

Embodiment two

As shown in FIG. 1 , as a further preferred implementation of the embodiment of the present invention, the stirring shaft 3 is further provided with a stirring paddle unit 5 , and the stirring paddle unit 5 is provided above the helical stirring unit 4 . The paddle unit 5 includes a plurality of paddles 51, and the paddles 52 of the paddles are axial-flow paddles or arrow-shaped paddles. When the stirring paddle 51 rotates, the fermented liquid is further pushed up and moved along the radial direction of the fermenter towards the inner wall of the tank. The shape of the blades of the stirring paddles 52 is not limited to the above-mentioned forms, and any blade shape that can cause the fermented liquid to push up and move along the radial direction of the fermenter toward the inner wall of the tank can be used in the present invention.

Further, in order to fully stir the fermented liquid in the fermenter, a plurality of stirring paddles 51 can be set, and the above-mentioned stirring paddles can be distributed equidistantly along the stirring shaft 3, so as to ensure that the fermented liquid in the middle and upper parts of the fermenter is fully stirred, further A plurality of stirring paddles 51 can be set according to the amount of fermented liquid in the fermenter, so as to improve the stirring efficiency and the dissolved oxygen amount of the fermented liquid. Preferably, the distance between any two connected stirring blades 51 may be equal to the pitch of the above-mentioned helical stirring belt.

During the fermentation process, the fermented liquid mixed with oxygen is continuously pushed up from the bottom of the fermenter by the spiral stirring unit 4, and when it reaches the position where the stirring paddle unit 5 is located, the stirring paddle unit 5 further stirs the fermented liquid, and the stirring paddle 51 and the stirring paddle When the paddle 52 rotates, the fermented liquid is further pushed up and moved along the radial direction of the fermenter to the inner wall of the tank, so that the middle and upper parts of the fermenter and the fermented liquid away from the stirring shaft are fully stirred, so that oxygen and The fermented liquid in the fermenter is further thoroughly mixed.

Embodiment Three

As shown in Figures 1 and 3, as a further preferred mode of the embodiment of the present invention, on the basis of the above-mentioned embodiment, a defoaming unit 6 is included, and the defoaming unit 6 is arranged on the stirring shaft 3, and is arranged on the stirring paddle unit 5 above.

Further, the defoaming unit 6 includes at least one second fixed arm 61, the second fixed arm 61 is arranged on the stirring shaft, and the plane where the second fixed arm 61 is located is perpendicular to the stirring shaft. One end of the second fixed arm 61 away from the stirring shaft 3 is provided with a stirring rod 62 along the axial direction of the stirring shaft 3, one end of the stirring rod 62 is fixedly connected with the second fixed arm 61, and the other end of the stirring rod 62 points to the bottom of the fermenter .

The main function of the defoaming unit 6 is that during the fermentation process, the microorganisms in the fermenter will generate carbon dioxide and form bubbles during the fermentation process, and the foam will float on the top of the liquid surface of the fermenter, and the stirring shaft 3 drives the defoaming unit 6 to stir , cutting and crushing the bubbles can eliminate the foam in the fermenter in time, avoid affecting the respiration and metabolism of microorganisms, and at the same time, prevent the foam from polluting the fermenter.

The specific working process of the present utility model is described below in conjunction with the above-mentioned embodiments.

The fermenter provided by the utility model is provided with a spiral stirring unit 4, a stirring paddle unit 5 and a defoaming unit 6 on the stirring shaft 3, and the spiral stirring unit 4 is arranged on the shaft section near the bottom of the fermenting tank of the stirring shaft 3, stirring The paddle unit 5 is disposed above the screw stirring unit 4 , and the defoaming unit 6 is disposed above the stirring paddle unit 5 . A motor 2 is provided on the upper end of the tank body 1, and the motor 2 is connected to a stirring shaft 3 arranged in the tank body 1. The motor 2 drives the stirring shaft 3 to rotate, and a ventilation pipe (not shown) is provided at the bottom of the fermentation tank, and the fermentation tank works At this time, the air compressor inputs the compressed air into the fermenter through the air pipe, and the fermented liquid mixed with oxygen is continuously pushed up by the spiral stirring unit 4 from the bottom of the fermenter, and when it reaches the position of the stirring paddle unit 5, the stirring paddle unit 5 The fermented liquid is further stirred, and the fermented liquid is pushed up and moved along the radial direction of the fermenter towards the inner wall of the tank. Due to the gravity of the fermented liquid itself, the fermented liquid falls along the inner wall of the fermenter to the bottom of the fermenter, spirally Stirring unit 4 pushes the fermented liquid in the bottom and middle of the fermenter continuously upwards, so that the fermented liquid in the fermented tank forms a direction from the bottom along the stirring axis, and then along the radial direction of the fermenter to the inner wall of the fermenter. Move, and then fall along the inner wall of the fermenter to the bottom of the fermenter, and then circulate from the bottom to the upward stirring. The above-mentioned improvement to the existing fermenter improves the stirring efficiency of the fermenter, increases the dissolved oxygen concentration of the fermented liquid, and meets the requirements of the fermentation tank. The oxygen demand of microorganisms improves the fermentation efficiency, and at the same time, overcomes the problems of complex structure and high cost of high-efficiency stirring fermenters.

It should be noted that the implementations in the above examples can be further combined or replaced, and the examples are only descriptions of preferred embodiments of the present utility model, and are not intended to limit the concept and scope of the present utility model, without departing from the present utility model Under the premise of the design idea, various changes and improvements made to the technical solution of the utility model by professional technicians in the field all belong to the protection scope of the utility model.

Claims (10)

1. a fermentation tank, including tank body, tank body is provided with motor, and what this motor connection one was arranged in tank body stirs Mix axle, it is characterised in that also include:

Auger unit, including fixed arm and hurricane band, described fixed arm is fixedly installed on described shaft, described One end away from described shaft of fixed arm is respectively and fixedly provided with a described hurricane band；

Stirring paddle unit, described stirring paddle unit is arranged on described shaft；

Described auger unit is arranged on the shaft part of close fermenter base of described shaft, described stirring paddle unit It is arranged on the top of described auger unit.

A kind of fermentation tank the most according to claim 1, it is characterised in that described auger unit includes multiple Fixed arm, described fixed arm is vertical with the axis of described shaft, and all described fixed arms are successively along the axle of described shaft To being distributed twist.

A kind of fermentation tank the most according to claim 1, it is characterised in that described hurricane band includes the first helicoid With the second helicoid, described fixed arm is fixed on described first helicoid.

A kind of fermentation tank the most according to claim 1, it is characterised in that described hurricane band by fermenter base to Fermentation tank top is in turn connected to form spiral type stirring band, and described spiral type stirs the band axis with described shaft for rotating Centrage is in the shape of a spiral.

A kind of fermentation tank the most according to claim 4, it is characterised in that described stirring paddle unit includes multiple stirring Mixing oar, the stirrer paddle of described stirring slurry is axial-flow type blade or flechette-type blade.

A kind of fermentation tank the most according to claim 5, it is characterised in that the plurality of stirring paddle is along described stirring Axle is equidistantly distributed.

A kind of fermentation tank the most according to claim 5, it is characterised in that the described stirring paddle that any two is connected Between the pitch of distance and described spiral type stirring band equal.

A kind of fermentation tank the most according to claim 1, it is characterised in that also include froth breaking unit, described froth breaking Unit is arranged on described shaft, and is arranged on above described stirring paddle unit.

A kind of fermentation tank the most according to claim 8, it is characterised in that described froth breaking unit includes at least one Second fixed arm, described second fixed arm is arranged on described shaft, and the plane at described second fixed arm place is hung down Straight in described shaft.

A kind of fermentation tank the most according to claim 9, it is characterised in that described second fixed arm stirs away from described The one end mixing axle is provided with the stirring rod along described shaft axial direction, one end of described stirring rod and described second fixed arm Fixing connection, the other end of described stirring rod points to fermenter base.