CN205163394U - Functional wound dressing of novel biology based on silk albumen - Google Patents
Functional wound dressing of novel biology based on silk albumen Download PDFInfo
- Publication number
- CN205163394U CN205163394U CN201520972304.4U CN201520972304U CN205163394U CN 205163394 U CN205163394 U CN 205163394U CN 201520972304 U CN201520972304 U CN 201520972304U CN 205163394 U CN205163394 U CN 205163394U
- Authority
- CN
- China
- Prior art keywords
- layer
- fibroin
- salient point
- wound
- wound dressing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 claims abstract description 56
- 102000016943 Muramidase Human genes 0.000 claims abstract description 11
- 108010014251 Muramidase Proteins 0.000 claims abstract description 11
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims abstract description 11
- 229960000274 lysozyme Drugs 0.000 claims abstract description 11
- 235000010335 lysozyme Nutrition 0.000 claims abstract description 11
- 239000004325 lysozyme Substances 0.000 claims abstract description 11
- 239000010410 layer Substances 0.000 claims description 92
- 108010022355 Fibroins Proteins 0.000 claims description 60
- 239000012790 adhesive layer Substances 0.000 claims description 29
- 238000007306 functionalization reaction Methods 0.000 claims description 24
- 239000011347 resin Substances 0.000 claims description 6
- 229920005989 resin Polymers 0.000 claims description 6
- 238000010030 laminating Methods 0.000 claims description 4
- 229920000742 Cotton Polymers 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims description 3
- 239000010409 thin film Substances 0.000 claims description 3
- 241000381602 Vachellia nebrownii Species 0.000 claims description 2
- 230000035876 healing Effects 0.000 abstract description 5
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 208000027418 Wounds and injury Diseases 0.000 description 65
- 206010052428 Wound Diseases 0.000 description 62
- 230000000694 effects Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 210000000416 exudates and transudate Anatomy 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The utility model discloses a functional wound dressing of novel biology based on silk albumen. Dressing includes overburden, medicine layer, silk protein layer in proper order and pastes the layer, wherein, the medicine layer is provided with a plurality of first bumps including the lysozyme, silk protein layer set up in the medicine layer and paste between the layer and laminate in the medicine layer, silk protein layer's area is less than the area on medicine layer, paste the layer be provided with a plurality of with mesh that first bump corresponds and be used for pasting the strip of pasting at wound edge, paste the strip set up in paste the edge all around on layer surface for paste on skin. The utility model discloses a medicine layer in dressing and paste and set up silk protein layer between the layer is protected the surface of a wound of wound through silk protein layer, and simultaneously, lysozyme through the medicine layer disinfects to the wound of skin, promotes the healing of wound.
Description
Technical field
This utility model relates to wound first-aid equipment, particularly relates to a kind of new bio functionalization wound dressing based on fibroin.
Background technology
The process of large area wound is difficult medical problem, such as large-area burns, large area scald etc., and wound is not easily wrapped up, easy infection, often needs skin-grafting, there is the problems such as skin supply source is limited.In large area wound care, particularly to having in the wound care of a large amount of sepage, usually use wound dressing to nurse, wound dressing has stronger wound exudate disposal ability, has absorb preferably and hold facility wound exudate.But when adopting current wound dressing to process wound, owing to lacking effective Wound protection effect, wound healing effect is not good.
In addition, in the process of wound healing, after the lasting covering wound of particularly wound dressing long period, the phenomenon of wound can be adhered when removing or change wound dressing, cause wound secondary damage.
Utility model content
Main purpose of the present utility model is to provide a kind of new bio functionalization wound dressing based on fibroin, be intended to solve the not good and wound of wound healing effect more change dressings time secondary damage defect.
For achieving the above object, this utility model provides a kind of new bio functionalization wound dressing based on fibroin, and it is characterized in that, described dressing comprises cover layer, medicine layer, fibroin layer and adhesive layer successively, wherein:
Described medicine layer is provided with multiple the first salient point comprising lysozyme, and described first salient point is arranged at the surface that described medicine layer and described fibroin laminating close, and the marginal position of described medicine layer is provided with bonding strip, for pasting with described adhesive layer;
Described fibroin layer to be arranged between described medicine layer and adhesive layer and to fit in described medicine layer, and the area of described fibroin layer is less than the area of described medicine layer;
Described adhesive layer is provided with mesh corresponding to multiple and described first salient point and pastes bar for what paste edge of wound, described in paste the edge that bar is arranged at described adhesive layer surface, for being pasted on skin.
Preferably, described first salient point is arranged at the surface that described medicine layer and fibroin laminating close equably.
Preferably, described medicine layer also arranges multiple the second salient point comprising moisture High hydrophilous resin, described adhesive layer is provided with mesh corresponding to multiple and described second salient point, when described adhesive layer and medicine layer are pasted, described second salient point is embedded in described mesh, by described fibroin layer and Wound contact to absorb the sepage of wound.
Preferably, described first salient point and the second salient point are circular salient point, rhombus salient point, square salient point or rectangle salient point.
Preferably, described mesh is circle, rhombus, square or rectangular.
Preferably, described cover layer is that waterproof cotton water thorn five spins layer of cloth.
Preferably, described medicine layer is gauze or medical plastic.
Preferably, described fibroin layer is the fibroin thin film be made into by fibroin.
Preferably, described adhesive layer is gauze or medical plastic.
Preferably, the shape of described dressing is rectangle, square, circle or oval.
Compared to prior art; new bio functionalization wound dressing based on fibroin described in the utility model have employed technique scheme; reach following technique effect: by arranging fibroin layer between the medicine layer in dressing and adhesive layer; protected by the wound surface of fibroin layer to wound; simultaneously; sterilized by the wound of lysozyme to skin of medicine layer; promote the healing of wound, the secondary injury to the wound of skin when being changed dressings by the four-layer structure design minimizing of dressing.
Accompanying drawing explanation
Fig. 1 is the cross-sectional view of this utility model based on the new bio functionalization wound dressing preferred embodiment of fibroin;
Fig. 2 is the planar structure schematic diagram of this utility model based on the preferred embodiment of the new bio functionalization wound dressing drug layer of fibroin;
Fig. 3 is the planar structure schematic diagram of this utility model based on the preferred embodiment of adhered layer in the new bio functionalization wound dressing of fibroin;
Fig. 4 cross-sectional view that to be this utility model be combined with mesh based on the new bio functionalization wound dressing bumps of fibroin.
The realization of this utility model object, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Detailed description of the invention
Reaching for further setting forth this utility model the technological means and effect that above-mentioned purpose takes, below in conjunction with accompanying drawing and preferred embodiment, describing in detail bright to detailed description of the invention of the present utility model, structure, feature and effect thereof.Should be appreciated that specific embodiment described by this utility model is only in order to explain this utility model, and be not used in restriction this utility model.
For realizing this utility model object; this utility model provides a kind of new bio functionalization wound dressing based on fibroin; by arranging fibroin layer between the medicine layer in dressing and adhesive layer; protected by the wound surface of fibroin layer to wound; simultaneously; sterilized by the wound of lysozyme to skin of medicine layer, alleviate the gradient of infection of skin, the secondary injury to the wound of skin when being changed dressings by the four-layer structure design minimizing of dressing.
As shown in Figure 1, Fig. 1 is the cross-sectional view of this utility model based on the new bio functionalization wound dressing preferred embodiment of fibroin.In the present embodiment, described in described dressing 100, dressing comprises cover layer 1, medicine layer 2, fibroin layer 3 and adhesive layer 4 successively.Described cover layer 1 is pasted with medicine layer 2, and described fibroin layer 3 is arranged between described medicine layer 2 and adhesive layer 4.
Wherein, described cover layer 1 can adopt waterproof cotton water to sting the five water proof non-woven gauzes spinning layer of cloth or other any appropriate and make, and this cover layer 1 can effectively prevent external environment condition from polluting dressing 100.。The surface that described cover layer 1 and medicine layer 2 are pasted scribbles medical cream, and cover layer 1 and medicine layer 2 are pasted.
As shown in Figure 2, Fig. 2 is the planar structure schematic diagram of this utility model based on the preferred embodiment of the new bio functionalization wound dressing drug layer of fibroin.Composition graphs 1 and Fig. 2; in the present embodiment; described medicine layer 2 is fitted with fibroin layer 3; because fibroin has good water penetration, breathability; on wound surface, there is stronger bonding force and without occupy-place phenomenon (namely not affecting the growth of position skin that it covers); not by bacterial penetration, therefore fibroin can be made thin film as fibroin layer 3 fits on medicine layer 2, plays a protective role to wound surface.The one side that described medicine layer 2 and fibroin layer 3 are pasted is provided with evenly or the salient point 20 of uneven distribution.Described salient point 20 may be, but not limited to, the salient point of circular salient point, rhombus salient point, square salient point, rectangle salient point or other shape.Described salient point 20 is the granule comprising lysozyme (Lysozyme), and this lysozyme can sterilize to wound.Due to described salient point 20 One's name is legion, in other embodiments, part salient point 20 comprises moisture High hydrophilous resin, and this moisture High hydrophilous resin, for absorbing the sepage of the wound of skin, is conducive to the healing of the wound of skin.That is, in the salient point that medicine layer 2 is all, part salient point 20 (also can be called the first salient point) comprises lysozyme, and another part salient point 20 (also can be called the second salient point) comprises moisture High hydrophilous resin.Described medicine layer 2 can be gauze or medical plastic.Described medicine layer 2 coordinates with fibroin layer 3; fibroin layer 3 can be utilized to protect wound surface on the one hand; the lysozyme in medicine layer 2 can be utilized to sterilize to wound on the other hand, be beneficial to the sepage that moisture High hydrophilous resin absorbs wound, the healing of wound can be promoted.
Further, the area of described fibroin layer 3 is less than the area of described medicine layer 2.Arrange bonding strip 21 at the marginal position of described medicine layer 2, described bonding strip 21 is pasted with described adhesive layer 4, and described medicine layer 2 is pasted together with adhesive layer 4.It should be noted that, described medicine layer 2 is a kind of adhesive structures that can tear from adhesive layer 4, and the described medicine layer 2 being namely pasted on described adhesive layer 4 surface can tear.That is, described medicine layer 2 and fibroin layer 3 can be changed, and are conducive to the healing of the wound of skin, reduce the secondary injury to the wound of skin when changing dressings.
As shown in Figure 3, Fig. 3 is the planar structure schematic diagram of this utility model based on the preferred embodiment of adhered layer in the new bio functionalization wound dressing of fibroin.As shown in Figure 4, Fig. 4 cross-sectional view that to be this utility model be combined with mesh based on the new bio functionalization wound dressing bumps of fibroin.
Composition graphs 2, Fig. 3 and Fig. 4; in the present embodiment; described adhesive layer 4 and the surperficial relevant position that medicine layer 2 is pasted comprise multiple and described first salient point and mesh 40 corresponding to described second salient point; described fibroin layer 3 is between described network interface 40 and described salient point 20; be conducive to fibroin layer 3 while protection wound surface, medicine layer 2 pairs of wounds fully sterilize.Described mesh 40 may be, but not limited to, the mesh 40 of circle, rhombus, square, rectangle or other shape.Described adhesive layer 4 another side comprises pastes bar 41, and this pastes the edge that bar 41 is positioned at adhesive layer 4, and this pastes bar 41 for pasting the edge of the wound of skin.
When described adhesive layer 4 is pasted with medicine layer 2; described salient point 20 to be embedded in described mesh 40 (as shown in Figure 4; salient point 20 is embedded into mesh 40) by the Wound contact of described fibroin layer 3 with skin; while the wound surface of skin is protected, wound is sterilized and/or absorbs wound exudate.Described adhesive layer 4 is gauze or medical plastic, this medical plastic frivolous (between 0.01 to 0.1 millimeter) and soft.
The shape of described dressing 100 may be, but not limited to, rectangle, square, circle or oval etc.
These are only preferred embodiment of the present utility model; not thereby the scope of the claims of the present utility model is limited; every utilize this utility model description and accompanying drawing content to do equivalent structure or equivalent function conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present utility model.
Claims (10)
1. based on a new bio functionalization wound dressing for fibroin, it is characterized in that, described dressing comprises cover layer, medicine layer, fibroin layer and adhesive layer successively, wherein:
Described medicine layer is provided with multiple the first salient point comprising lysozyme, and described first salient point is arranged at the surface that described medicine layer and described fibroin laminating close, and the marginal position of described medicine layer is provided with bonding strip, for pasting with described adhesive layer;
Described fibroin layer to be arranged between described medicine layer and adhesive layer and to fit in described medicine layer, and the area of described fibroin layer is less than the area of described medicine layer;
Described adhesive layer is provided with mesh corresponding to multiple and described first salient point and pastes bar for what paste edge of wound, described in paste the edge that bar is arranged at described adhesive layer surface, for being pasted on skin.
2. as claimed in claim 1 based on the new bio functionalization wound dressing of fibroin, it is characterized in that, described first salient point is arranged at the surface that described medicine layer and fibroin laminating close equably.
3. as claimed in claim 1 based on the new bio functionalization wound dressing of fibroin, it is characterized in that, described medicine layer also arranges multiple the second salient point comprising moisture High hydrophilous resin, described adhesive layer is provided with mesh corresponding to multiple and described second salient point, when described adhesive layer and medicine layer are pasted, described second salient point is embedded in described mesh, by described fibroin layer and Wound contact to absorb the sepage of wound.
4., as claimed in claim 3 based on the new bio functionalization wound dressing of fibroin, it is characterized in that, described first salient point and the second salient point are circular salient point, rhombus salient point, square salient point or rectangle salient point.
5. the new bio functionalization wound dressing based on fibroin according to any one of Claims 1-4, it is characterized in that, described mesh is circle, rhombus, square or rectangular.
6. the new bio functionalization wound dressing based on fibroin according to any one of Claims 1-4, is characterized in that, described cover layer is that waterproof cotton water thorn five spins layer of cloth.
7. the new bio functionalization wound dressing based on fibroin according to any one of Claims 1-4, it is characterized in that, described medicine layer is gauze or medical plastic.
8. the new bio functionalization wound dressing based on fibroin according to any one of Claims 1-4, is characterized in that, described fibroin layer is the fibroin thin film be made into by fibroin.
9. the new bio functionalization wound dressing based on fibroin according to any one of Claims 1-4, it is characterized in that, described adhesive layer is gauze or medical plastic.
10. the new bio functionalization wound dressing based on fibroin according to any one of Claims 1-4, the shape of described dressing is rectangle, square, circle or oval.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520972304.4U CN205163394U (en) | 2015-11-28 | 2015-11-28 | Functional wound dressing of novel biology based on silk albumen |
| PCT/CN2015/098557 WO2017088227A1 (en) | 2015-11-28 | 2015-12-24 | Novel bio-functionalized wound dressing based on fibroin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520972304.4U CN205163394U (en) | 2015-11-28 | 2015-11-28 | Functional wound dressing of novel biology based on silk albumen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205163394U true CN205163394U (en) | 2016-04-20 |
Family
ID=55727440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520972304.4U Expired - Fee Related CN205163394U (en) | 2015-11-28 | 2015-11-28 | Functional wound dressing of novel biology based on silk albumen |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN205163394U (en) |
| WO (1) | WO2017088227A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107296981A (en) * | 2017-07-12 | 2017-10-27 | 江苏科技大学 | A kind of fibroin biological support and its preparation method and application |
| WO2017219334A1 (en) * | 2016-06-23 | 2017-12-28 | 彭鹏 | Dressing |
| CN107744601A (en) * | 2017-09-06 | 2018-03-02 | 盐城工业职业技术学院 | A kind of 3 D-printing wound covering material based on silk microballoon bio-ink and preparation method thereof |
| CN113398313A (en) * | 2021-06-08 | 2021-09-17 | 上海大学 | Multilayer-structure composite dressing acting on wound surface and preparation method thereof |
| CN114631934A (en) * | 2022-03-14 | 2022-06-17 | 中国人民解放军联勤保障部队第九二〇医院 | Dressing capable of creating hypoxia microenvironment to promote early healing of acute wound |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983507B (en) * | 2022-05-27 | 2025-01-03 | 东南大学 | A processing method for silk composite hemostatic airbag |
| CN119971120B (en) * | 2025-01-21 | 2025-09-09 | 鹏拓生物科技(杭州)有限公司 | A sutureable membrane with adhesion ability and preparation method thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2009564A6 (en) * | 1988-03-11 | 1989-10-01 | Donati Bagnoli Claudio | Plaster for skin wound contg. layer of freeze dried collagen - used to stimulate healing, is attached by adhesive |
| ATE376410T1 (en) * | 2001-05-16 | 2007-11-15 | Susanna Elizabeth Chalmers | WOUND DRESSINGS AND WOUND TREATMENT COMPOSITIONS |
| TWM256747U (en) * | 2004-03-05 | 2005-02-11 | Fu Burg Ind Co Ltd | Wound dressing material structure |
| CN101804218A (en) * | 2010-04-13 | 2010-08-18 | 王艳 | Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive |
| CN103271794B (en) * | 2013-06-17 | 2015-08-05 | 上海微纳科技有限公司 | Biological antibiotic based on bedsore wound is applied ointment or plaster |
| CN204683912U (en) * | 2015-05-18 | 2015-10-07 | 绍兴文理学院 | A kind of regenerated cellulose collagen protein composite wound dressing |
-
2015
- 2015-11-28 CN CN201520972304.4U patent/CN205163394U/en not_active Expired - Fee Related
- 2015-12-24 WO PCT/CN2015/098557 patent/WO2017088227A1/en not_active Ceased
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017219334A1 (en) * | 2016-06-23 | 2017-12-28 | 彭鹏 | Dressing |
| CN107296981A (en) * | 2017-07-12 | 2017-10-27 | 江苏科技大学 | A kind of fibroin biological support and its preparation method and application |
| CN107296981B (en) * | 2017-07-12 | 2019-10-15 | 江苏科技大学 | A kind of silk protein bioscaffold and its preparation method and application |
| CN107744601A (en) * | 2017-09-06 | 2018-03-02 | 盐城工业职业技术学院 | A kind of 3 D-printing wound covering material based on silk microballoon bio-ink and preparation method thereof |
| CN107744601B (en) * | 2017-09-06 | 2020-09-25 | 盐城工业职业技术学院 | Three-dimensional printing wound coating material based on silk microsphere biological ink and preparation method thereof |
| CN113398313A (en) * | 2021-06-08 | 2021-09-17 | 上海大学 | Multilayer-structure composite dressing acting on wound surface and preparation method thereof |
| CN114631934A (en) * | 2022-03-14 | 2022-06-17 | 中国人民解放军联勤保障部队第九二〇医院 | Dressing capable of creating hypoxia microenvironment to promote early healing of acute wound |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017088227A1 (en) | 2017-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160420 Termination date: 20201128 |