CN205094668U - A fixing device for big rattail blood sampling - Google Patents

A fixing device for big rattail blood sampling Download PDF

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Publication number
CN205094668U
CN205094668U CN201520815962.2U CN201520815962U CN205094668U CN 205094668 U CN205094668 U CN 205094668U CN 201520815962 U CN201520815962 U CN 201520815962U CN 205094668 U CN205094668 U CN 205094668U
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rat
compression screw
cage
rat cage
fixing device
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葛庆之
汪正东
闫子胜
张幸
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Nanjing University of Information Science and Technology
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Nanjing University of Information Science and Technology
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Abstract

本实用新型公开了一种用于大鼠尾静脉采血的固定装置,包括固定塞、头罩、第一压紧螺钉、第二压紧螺钉、万向支撑管、红外线理疗灯和两端均开口的桶状鼠仓,所述头罩和固定塞分别滑动设置在鼠仓的内腔内,第一压紧螺钉和第二压紧螺钉分别螺纹连接在鼠仓的左右两侧,且第一压紧螺钉一端穿过鼠仓侧壁,并将头罩紧抵于鼠仓内,第二压紧螺钉一端穿过鼠仓侧壁,并将固定塞紧抵于鼠仓内,红外线理疗灯通过万向支撑管固定连接在鼠仓外壁上;所述固定塞上设有安置腔和安置孔,所述安置腔和安置孔相贯通。本实用新型固定装置可在非麻醉状态下对大鼠进行尾静脉采血,对大鼠损伤较小,可反复多次采血,采血量足,不易凝血,操作简单,时间短,并且可实现单人操作。

The utility model discloses a fixing device for rat tail vein blood collection, which comprises a fixing plug, a head cover, a first compression screw, a second compression screw, a universal support tube, an infrared physiotherapy lamp and openings at both ends. The barrel-shaped rat cage, the head cover and the fixed plug are respectively slidably arranged in the inner cavity of the rat cage, the first compression screw and the second compression screw are threaded on the left and right sides of the rat cage respectively, and the first compression screw One end of the tightening screw passes through the side wall of the rat cage, and the head cover is pressed against the rat cage; one end of the second compression screw passes through the side wall of the rat cage, and the fixing plug is tightly pressed into the rat cage, and the infrared physiotherapy lamp passes through the The supporting pipe is fixedly connected to the outer wall of the rat barn; the fixing plug is provided with a placement cavity and a placement hole, and the placement cavity and the placement hole are connected. The fixing device of the utility model can collect blood from the tail vein of rats in a non-anesthetized state, has less damage to the rats, can repeatedly collect blood, has a sufficient amount of blood, is not easy to coagulate, is simple to operate, takes a short time, and can be realized by a single person. operate.

Description

一种用于大鼠尾静脉采血的固定装置A fixation device for blood collection from tail vein of rats

技术领域:Technical field:

本实用新型涉及一种用于大鼠尾静脉采血的固定装置。 The utility model relates to a fixing device for rat tail vein blood collection.

背景技术:Background technique:

在大鼠实验中经常需要对大鼠进行采血。目前,主要的大鼠的采血方法有:断尾采血、眼眶静脉采血,断头采血、心脏穿刺采血、腹主动脉采血、颈外静脉和颈总动脉采血,以上采血方法大多在麻醉状态下进行,对动物损伤较大,且不能反复多次采血。 Rat experiments often require blood collection from rats. At present, the main blood collection methods for rats are: tail docking blood collection, orbital vein blood collection, decapitation blood collection, cardiac puncture blood collection, abdominal aorta blood collection, external jugular vein and common carotid artery blood collection, most of the above blood collection methods are carried out under anesthesia , causing greater damage to animals, and repeated blood collection cannot be repeated.

为了克服上述问题,申请日为2012年7月12日,专利号为CN201210239909.3的中国专利公开了一种实验大鼠采血方法:一只手固定大鼠,另一只手的拇指和食指捏住鼠尾巴两侧,另一位实验人员手持尾静脉采血针沿着一侧尾静脉向心方向穿刺进针,穿刺进入尾静脉后,血液进入针头,并沿着软质硅胶管流出,随后用EP采血管接住,待血液流出,等大鼠稳定后,用捏鼠尾的拇指及食指轻轻按摩鼠尾,有利于血液流出。 In order to overcome the above-mentioned problems, the Chinese patent with the application date of July 12, 2012 and the patent number CN201210239909.3 discloses a blood collection method for experimental rats: one hand fixes the rat, and the thumb and forefinger of the other hand pinch Live on both sides of the tail of the rat, and another experimenter holds a tail vein blood collection needle and punctures the needle along one side of the tail vein in the direction of the heart. After the puncture enters the tail vein, the blood enters the needle and flows out along the soft silicone tube. Catch the EP blood collection tube, wait for the blood to flow out, and when the rat is stable, gently massage the tail of the rat with the thumb and forefinger pinching the tail, which is beneficial for the blood to flow out.

经过实际操作,上述方法有不合理之处。首先,将尾静脉采血针插入大鼠的尾静脉后,因为没有造成负压,血液沿着采血针的软质硅胶管流出的速度非常缓慢,容易凝血。其次,上述方法需要两个人配合操作,实验过程较为繁琐。 After actual operation, the above method has unreasonable parts. First of all, after inserting the tail vein blood collection needle into the tail vein of the rat, because there is no negative pressure, the blood flows out very slowly along the soft silicone tube of the blood collection needle, which is easy to coagulate. Secondly, the above method requires two people to cooperate with the operation, and the experimental process is relatively cumbersome.

因此,确有必要对现有技术进行改进以解决现有技术之不足。 Therefore, it is necessary to improve the prior art to solve the deficiencies of the prior art.

发明内容:Invention content:

本实用新型是为了解决上述现有技术存在的问题而提供一种用于大鼠尾静脉采血的固定装置。 The utility model provides a fixing device for rat tail vein blood collection in order to solve the above-mentioned problems in the prior art.

本实用新型所采用的技术方案有:一种用于大鼠尾静脉采血的固定装置,包括固定塞、头罩、第一压紧螺钉、第二压紧螺钉、万向支撑管、红外线理疗灯和两端均开口的桶状鼠仓,所述头罩和固定塞分别滑动设置在鼠仓的内腔内,第一压紧螺钉和第二压紧螺钉分别螺纹连接在鼠仓的左右两侧,且第一压紧螺钉一端穿过鼠仓侧壁,并将头罩紧抵于鼠仓内,第二压紧螺钉一端穿过鼠仓侧壁,并将固定塞紧抵于鼠仓内,红外线理疗灯通过万向支撑管固定连接在鼠仓外壁上; The technical scheme adopted by the utility model includes: a fixing device for rat tail vein blood collection, including a fixing plug, a hood, a first compression screw, a second compression screw, a universal support tube, and an infrared physiotherapy lamp and a barrel-shaped rat cage with openings at both ends, the hood and the fixing plug are respectively slidably arranged in the inner chamber of the rat cage, and the first compression screw and the second compression screw are respectively threaded on the left and right sides of the rat cage , and one end of the first compression screw passes through the side wall of the rat cage, and presses the hood tightly into the rat cage, and one end of the second compression screw passes through the side wall of the rat cage, and firmly presses the fixed plug into the rat cage, The infrared physiotherapy lamp is fixedly connected to the outer wall of the rat barn through a universal support tube;

所述固定塞上设有安置腔和安置孔,所述安置腔和安置孔相贯通。 The fixing plug is provided with a placement cavity and a placement hole, and the placement cavity and the placement hole are connected.

进一步地,所述头罩包括柱形连接体和锥形罩体,所述柱形连接体与锥形罩体固定连接,第一压紧螺钉一端穿过鼠仓侧壁,并抵接于柱形连接体外壁上。 Further, the hood includes a cylindrical connecting body and a conical covering body, the cylindrical connecting body is fixedly connected with the conical covering body, one end of the first compression screw passes through the side wall of the hamster, and abuts against the column On the outer wall of the shape connector.

进一步地,所述安置腔为向右端收缩的斗形腔。 Further, the placement cavity is a bucket-shaped cavity that shrinks toward the right end.

进一步地,所述鼠仓采用不透明塑料制成。 Further, the rat cage is made of opaque plastic.

本实用新型具有如下有益效果: The utility model has the following beneficial effects:

本实用新型固定装置可在非麻醉状态下对大鼠进行尾静脉采血,对大鼠损伤较小,可反复多次采血,采血量足,不易凝血,操作简单,时间短,并且可实现单人操作。 The fixing device of the utility model can collect blood from the tail vein of rats in a non-anesthetized state, has less damage to the rats, can repeatedly collect blood, has sufficient blood collection, is not easy to coagulate, is simple to operate, and takes a short time. operate.

附图说明:Description of drawings:

图1为本实用新型结构图。 Fig. 1 is a structural diagram of the utility model.

具体实施方式:detailed description:

下面结合附图对本实用新型作进一步的说明。 Below in conjunction with accompanying drawing, the utility model is further described.

请参照图1所示,本实用新型一种用于大鼠尾静脉采血的固定装置,包括鼠仓1、固定塞2、头罩3、第一压紧螺钉4、第二压紧螺钉5、万向支撑管6和红外线理疗灯7,鼠仓1为两端均开口的桶状结构,固定塞2和头罩3分别置于鼠仓1左右两端,且均可在鼠仓1的内腔中滑动,第一压紧螺钉4螺纹连接在鼠仓1的左端,且第一压紧螺钉4的一端穿过鼠仓1侧壁,并将头罩3紧抵于鼠仓1内。第二压紧螺钉5螺纹连接在鼠仓1的右端,且第二压紧螺钉5的一端穿过鼠仓1侧壁,并将固定塞2紧抵于鼠仓1内。红外线理疗灯7通过万向支撑管6固定连接在鼠仓1的外壁上。 Please refer to shown in Fig. 1, a kind of fixing device that is used for rat tail vein blood collection of the present utility model, comprises mouse compartment 1, fixing plug 2, head shield 3, first compression screw 4, the second compression screw 5, The universal support tube 6 and the infrared physiotherapy lamp 7, the rat bin 1 is a barrel-shaped structure with openings at both ends, the fixed plug 2 and the head cover 3 are respectively placed at the left and right ends of the rat bin 1, and can be placed inside the rat bin 1. Sliding in the cavity, the first compression screw 4 is threadedly connected to the left end of the mouse cage 1, and one end of the first compression screw 4 passes through the side wall of the mouse cage 1, and the hood 3 is tightly pressed against the mouse cage 1. The second compression screw 5 is threadedly connected to the right end of the mouse cage 1, and one end of the second compression screw 5 passes through the side wall of the mouse cage 1, and the fixing plug 2 is pressed against the mouse cage 1. The infrared physiotherapy lamp 7 is fixedly connected on the outer wall of the rat cage 1 through the universal support tube 6 .

本实用新型为方便鼠仓1内的大鼠尾巴伸出鼠仓1外,在固定塞2上设有安置腔21和安置孔22,该安置腔21和安置孔22相贯通,且同轴线设置。本实用新型中的安置腔21为向右端收缩的斗形腔。 In order to make it easier for the tail of the rat in the rat cage 1 to extend out of the rat cage 1, the utility model is provided with a placement cavity 21 and a placement hole 22 on the fixing plug 2, the placement cavity 21 and the placement hole 22 are connected, and the coaxial set up. The placement cavity 21 in the utility model is a bucket-shaped cavity that shrinks to the right end.

头罩3包括锥形罩体32以及与锥形罩体32固定连接的柱形连接体31,柱形连接体31滑动置于鼠仓1的内腔中,第一压紧螺钉4一端穿过鼠仓侧壁,并抵接于柱形连接体31外壁上。 The hood 3 includes a cone-shaped cover body 32 and a cylindrical connecting body 31 fixedly connected with the conical covering body 32. The cylindrical connecting body 31 is slidably placed in the inner cavity of the rat cage 1, and one end of the first compression screw 4 passes through The side wall of the mouse silo, and abuts against the outer wall of the cylindrical connecting body 31 .

为防止大鼠见光易狂躁,导致大鼠不愿进入鼠仓,本实用新型中的鼠仓1采用不透明塑料制成。 In order to prevent rats from being easily manic when they see light, causing rats to be reluctant to enter the rat cage, the rat cage 1 in the utility model is made of opaque plastic.

将大鼠置于鼠仓1内,并使得该大鼠的尾巴通过固定塞2上的安置孔22伸出鼠仓1外,根据老鼠体积大小,调节固定塞2和头罩3,并分别将固定塞2和头罩3固定。打开红外线理疗灯7照射鼠仓,鼠仓内的温度升高,使大鼠体内血液循环加快,直到大鼠耳朵由白色变为红色,此过程大约需要5-10分钟。用酒精棉擦拭鼠尾,使鼠尾静脉充盈肿胀,随后将0.45mm静脉输液针和注射器相连接,在距离鼠尾末端向上1/3处,找准大鼠尾部静脉,穿刺操作者右手持针,左手拇指在上、食指在下捏住鼠尾,将鼠尾略弯曲,针头微微向斜下方刺破表皮,然后针头方向平行于鼠尾继续进针1-1.5cm,此时,针头出现回血,随后拉动注射器的活塞柄,制造负压抽取血液,取血结束后,用脱脂棉球按压针眼部位30秒,确定止血后从固定装置中取出大鼠。 The rat is placed in the rat cage 1, and the tail of the rat is stretched out of the rat cage 1 through the placement hole 22 on the fixed plug 2, and the fixed plug 2 and the hood 3 are adjusted according to the size of the mouse, and respectively Fixed plug 2 and hood 3 are fixed. Turn on the infrared physiotherapy lamp 7 to irradiate the rat cage, the temperature in the rat cage increases, and the blood circulation in the rat body is accelerated until the rat's ears turn from white to red, and this process takes about 5-10 minutes. Wipe the rat tail with alcohol cotton to make the rat tail vein swell and swell, then connect the 0.45mm intravenous infusion needle to the syringe, locate the tail vein of the rat at the upper 1/3 of the distance from the end of the rat tail, and the puncture operator holds the needle in his right hand , pinch the tail of the rat with the thumb of the left hand and the index finger below, bend the tail slightly, pierce the epidermis with the needle slightly obliquely downward, and then continue to insert the needle 1-1.5cm parallel to the tail, at this time, the needle returns blood, Then pull the piston handle of the syringe to create a negative pressure to draw blood. After the blood is taken, press the needle eye with a cotton ball for 30 seconds, and take out the rat from the immobilization device after confirming hemostasis.

以上所述仅是本实用新型的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本实用新型原理的前提下还可以作出若干改进,这些改进也应视为本实用新型的保护范围。 The above is only a preferred embodiment of the utility model, and it should be pointed out that for those of ordinary skill in the art, some improvements can be made without departing from the principle of the utility model, and these improvements should also be regarded as the present invention. Protection scope of utility model.

Claims (4)

1.一种用于大鼠尾静脉采血的固定装置,其特征在于:包括固定塞(2)、头罩(3)、第一压紧螺钉(4)、第二压紧螺钉(5)、万向支撑管(6)、红外线理疗灯(7)和两端均开口的桶状鼠仓(1),所述头罩(3)和固定塞(2)分别滑动设置在鼠仓(1)的内腔内,第一压紧螺钉(4)和第二压紧螺钉(5)分别螺纹连接在鼠仓(1)的左右两侧,且第一压紧螺钉(4)一端穿过鼠仓侧壁,并将头罩(3)紧抵于鼠仓内,第二压紧螺钉(5)一端穿过鼠仓侧壁,并将固定塞(2)紧抵于鼠仓内,红外线理疗灯(7)通过万向支撑管(6)固定连接在鼠仓(1)外壁上; 1. A fixing device for rat tail vein blood collection, characterized in that: it comprises a fixing plug (2), a hood (3), a first compression screw (4), a second compression screw (5), A universal support tube (6), an infrared physiotherapy lamp (7) and a barrel-shaped rat cage (1) with openings at both ends. In the inner cavity of the hamster, the first compression screw (4) and the second compression screw (5) are respectively threaded on the left and right sides of the rat cage (1), and one end of the first compression screw (4) passes through the rat cage side wall, and press the hood (3) tightly into the mouse chamber, one end of the second compression screw (5) passes through the side wall of the mouse chamber, and press the fixing plug (2) tightly into the mouse chamber, and the infrared physiotherapy lamp (7) Fixedly connected to the outer wall of the rat cage (1) through the universal support tube (6); 所述固定塞(2)上设有安置腔(21)和安置孔(22),所述安置腔(21)和安置孔(22)相贯通。 The fixing plug (2) is provided with a placement cavity (21) and a placement hole (22), and the placement cavity (21) and the placement hole (22) are connected. 2.如权利要求1所述的用于大鼠尾静脉采血的固定装置,其特征在于:所述头罩(3)包括柱形连接体(31)和锥形罩体(32),所述柱形连接体(31)与锥形罩体(32)固定连接,第一压紧螺钉(4)一端穿过鼠仓侧壁,并抵接于柱形连接体(31)外壁上。 2. The fixing device for rat tail vein blood collection according to claim 1, characterized in that: the hood (3) includes a cylindrical connector (31) and a conical cover (32), the The cylindrical connecting body (31) is fixedly connected with the conical cover body (32), and one end of the first compression screw (4) passes through the side wall of the hamster, and abuts against the outer wall of the cylindrical connecting body (31). 3.如权利要求1所述的用于大鼠尾静脉采血的固定装置,其特征在于:所述安置腔(21)为向右端收缩的斗形腔。 3. The fixing device for rat tail vein blood collection according to claim 1, characterized in that: the placement cavity (21) is a funnel-shaped cavity shrinking to the right. 4.如权利要求1所述的用于大鼠尾静脉采血的固定装置,其特征在于:所述鼠仓(1)采用不透明塑料制成。 4. The fixing device for blood collection from tail vein of rats according to claim 1, characterized in that: the rat cage (1) is made of opaque plastic.
CN201520815962.2U 2015-10-22 2015-10-22 A fixing device for big rattail blood sampling Expired - Fee Related CN205094668U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105919605A (en) * 2016-04-22 2016-09-07 广东温氏食品集团股份有限公司 Mouse negative pressure blood collecting device
CN107334560A (en) * 2017-07-24 2017-11-10 上海市第人民医院 A kind of multi-functional tail vein injection platform
CN107822765A (en) * 2017-11-28 2018-03-23 南京医科大学 A kind of experiment of nude mouse device for contactless thermotherapy research
CN111317590A (en) * 2020-02-27 2020-06-23 中国人民解放军疾病预防控制中心 Adjustable rat restraint device for noninvasive blood pressure monitoring

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105919605A (en) * 2016-04-22 2016-09-07 广东温氏食品集团股份有限公司 Mouse negative pressure blood collecting device
CN107334560A (en) * 2017-07-24 2017-11-10 上海市第人民医院 A kind of multi-functional tail vein injection platform
CN107334560B (en) * 2017-07-24 2023-11-03 上海市第一人民医院 Multifunctional rat tail intravenous injection platform
CN107822765A (en) * 2017-11-28 2018-03-23 南京医科大学 A kind of experiment of nude mouse device for contactless thermotherapy research
CN111317590A (en) * 2020-02-27 2020-06-23 中国人民解放军疾病预防控制中心 Adjustable rat restraint device for noninvasive blood pressure monitoring

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