CN204910431U - Heart in situ perfusion pipe - Google Patents

Abstract

The utility model discloses a heart perfusion catheter in situ, which belongs to the technical field of heart treatment equipment. The perfusion catheter includes an outer coating layer and two inner tubes inside the outer coating layer, and the two inner tubes are covered by the outer coating layer. , its overall shape is composed of a straight section and a hook section, the hook section is composed of an arc section and a straight section, and the arc section is connected with the straight section; the two inner tubes corresponding to the straight section are one One is closed at the end and open on the side, and the other is open at the end and the inner tube is open at the side, and its opening runs through the outer cladding layer. The cardiac in-situ perfusion catheter of the utility model is used in conjunction with a hydraulic pump, a physiological signal collector, a signal discriminator and an infusion pump). The inner tube with an open end transmits a pressure signal to the physiological signal collector through the open end, and the pressure signal is discriminated by the signal After the device is processed, start and stop signals are sent to the infusion pump, and the infusion pump delivers liquid to the heart through the inner tube with the side opening. The utility model is helpful to realize long-term cardiac targeted perfusion and has high safety.

Description

A Catheter for In Situ Cardiac Perfusion

technical field

The utility model relates to a perfusion catheter, in particular to a catheter used in in situ perfusion of the heart, and belongs to the technical field of medical devices.

Background technique

Ischemic heart disease is a common disease that seriously threatens human health. Current conventional treatments have limited curative effect. Stem cell transplantation and cytokine infusion have shown great potential in the treatment of ischemic heart disease, but it is necessary for therapeutic drugs to play a therapeutic role in situ in the heart to avoid uptake and utilization of peripheral non-target tissues.

At present, a number of clinical trials on the treatment of ischemic heart disease with cytokine drugs have been carried out at home and abroad. These two methods are combined with subcutaneous injection for continuous administration. Due to the high price of cytokine protein preparations, the half-life in vivo is usually very short (several minutes), and when administered intravenously or subcutaneously, most of them have been degraded or combined with non-target cells when they reach the target organ through the absorption cycle; while the first dose is administered through the coronary artery Drugs infused within the heart are quickly washed out to extracardiac tissues along with the blood flow. Therefore, the problem of the current drug administration method is that the therapeutic effect on the target organ of the heart is not obvious. , Body fluid penetration, edema performance is obvious. Finding a new route of administration is of great significance to improving the therapeutic effect.

At present, the existing route of drug administration for heart disease is to use a microcatheter or a balloon to enter the target vessel through the coronary artery combined with continuous intravenous or subcutaneous administration. The problems with this method are: ①. However, the drug quickly spreads to the peripheral tissue due to blood flow washing; ②. The catheter cannot be left in the coronary artery for a long time.

The intracoronary perfusion method is implemented according to the coronary intervention technique, guiding the catheter into the coronary artery, the guide wire enters the target blood vessel along the guiding catheter, and then releases the microcatheter or balloon to the target position along the guidewire, and finally injects the fluid along the microcatheter target vessel. Since the guiding catheter needs to enter the coronary artery, it is easy to damage the blood vessel or the catheter is left in the coronary artery for a long time to cause thrombosis in the coronary artery.

Utility model content

In view of this, the utility model provides a cardiac perfusion catheter in situ, which is not easy to pop into the coronary artery opening and has high safety, which is helpful to realize long-term cardiac targeted perfusion.

A cardiac perfusion catheter in situ, the perfusion catheter includes an outer cladding layer and two inner tubes inside the outer cladding layer, the outer surfaces of the two inner tubes are completely covered by the outer cladding layer, and its overall shape It is composed of a straight section and a hook section. The hook section is composed of an arc section and a straight section. The arc section connects with the straight section; The side is open, the other is an end opening, the opening of the side opening inner tube runs through the outer cladding layer, and the ends of the two inner tubes corresponding to the straight section are open structures.

Further, the outer cladding layer is vulcanized by polyethylene material and steel wire mesh, the polyethylene material determines the hardness, shape and friction with the intima of the blood vessel, and the steel wire mesh forms the skeleton of the perfusion catheter, so that the perfusion catheter The lumen will not collapse and has anti-fracture effect.

Further, the length of the straight portion of the perfusion catheter is 105-110 cm, and the outer diameter of the catheter is 5F-7F.

Further, the arc radius of the arc section of the hook portion of the perfusion catheter is 3-5mm, and the length of the straight section is 8-12mm.

Working principle: The cardiac in situ perfusion catheter of the present utility model is used in conjunction with a physiological signal collector, a signal discriminator and an infusion pump. When in use, the cardiac in situ perfusion catheter of the present utility model is placed on the corresponding part of the heart through the femoral artery. The side opening on the straight section of the hook corresponds to the position of the coronary sinus ostium, and the two inner tubes corresponding to the straight section are respectively connected to the physiological signal collector and the infusion pump through the infusion tube. The inner tube senses the pressure at the position through the open end, and transmits the pressure signal to the physiological signal collector. The pressure signal is processed by the signal discriminator to obtain the time course of the diastolic period. The signal discriminator controls the infusion pump to follow the law of the diastolic period. When activated, fluid is delivered to the heart through the inner tube that opens on the side.

Beneficial effect:

1. The end of the catheter of the present invention is straight and does not have an upwardly tilted hook, which prevents the catheter from bouncing into the opening of the coronary artery during the release process, which can prevent damage and has high safety.

2. The interior of the utility model adopts a double-chamber structure. The catheter only needs to be released at the ostium of the coronary artery and does not enter the coronary artery. The input liquid enters the ostium of the sinus through the chamber of the side opening, which can avoid damage to blood vessels due to intracoronary operations. Or the long-term indwelling catheter in the coronary artery causes thrombosis in the coronary artery.

Description of drawings

Fig. 1 is the outline structure schematic diagram of the present utility model;

Fig. 2 is a structural representation of the straight section of the utility model;

Fig. 3 is the application schematic diagram of the utility model.

Among them, 1-outer cladding layer, 2-end opening, 3-inner tube I, 4-side opening, 5-inner tube II, 6-straight part, 7-hook part.

Detailed ways

The utility model will be described in detail below in conjunction with the accompanying drawings and examples.

As shown in accompanying drawings 1 and 2, the utility model provides a cardiac perfusion catheter in situ. The perfusion catheter includes an outer cladding layer 1 and an inner tube I3 and an inner tube II5 inside the outer cladding layer. The layer is vulcanized by polyethylene material and steel wire mesh; the outer surface of the inner pipe I3 and inner pipe II5 is completely covered by the outer cladding layer 1, and its overall shape is composed of a straight section 6 and a hook section 7. The hook part 7 is composed of an arc segment and a straight segment, and the arc segment is connected to the straight segment 6; the end of the inner tube I3 corresponding to the straight segment is closed and has a side opening 4, and the end of the inner tube II5 Opening, the side opening of the inner tube I3 runs through the outer cladding layer 1, and the ends of the inner tube I3 and the inner tube II5 corresponding to the straight section are open structures.

The length of the straight section of the perfusion catheter is 110cm, the outer diameter of the catheter is 6F, the arc radius of the arc section of the hook part of the perfusion catheter is 4mm, and the length of the straight section is 10mm.

Working principle: the cardiac in situ perfusion catheter of the present utility model is used in conjunction with the physiological signal collector, signal discriminator and infusion pump. When in use, the cardiac in situ perfusion catheter of the present utility model is placed through the femoral artery into the The corresponding part of the heart shown in the figure, the end of the straight line section of the hook part 7 corresponds to the position of the sinus ostium, the inner tube II 5 transmits the pressure signal to the physiological signal collector through the open end, the pressure signal is processed by the signal discriminator, and the signal discriminator detects a pressure signal When the position in the wave unit (corresponding to the diastolic period of the heart), a start signal is sent to the infusion pump, and the fluid is delivered to the heart through the side opening of the inner tube I3; before the rising branch of the next pressure wave (corresponding to the systolic period of the heart), Send a termination signal.

To sum up, the above are only preferred embodiments of the present utility model, and are not intended to limit the protection scope of the present utility model. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present utility model shall be included in the protection scope of the present utility model.

Claims (4)

1. a heart in-situ perfusion conduit, it is characterized in that, pipe in described perfusion cannula comprise external coating and external coating inside two, the outer surface of described two interior pipes is completely coated by external coating, its monnolithic case is made up of straight part and hook portion, described hook portion is made up of segmental arc and straightway, and segmental arc connects with straight part; Two interior pipes one of described straightway corresponding position are endcapped and side opening, and another is distal opening, and its opening of interior pipe of side opening runs through external coating, and the end of two interior pipes that described straight part is corresponding is open end.

2. heart in-situ perfusion conduit as claimed in claim 1, it is characterized in that, described external coating is formed by polythene material and steel wire sulfuration.

3. heart in-situ perfusion conduit as claimed in claim 1 or 2, is characterized in that, described perfusion cannula straight part be length 105-110cm, the external diameter of conduit is 5F-7F.

4. heart in-situ perfusion conduit as claimed in claim 1 or 2, it is characterized in that, the arc radius of the segmental arc of described perfusion cannula hook portion is 3-5mm, and the length of straightway is 8-12mm.