CN204188442U - A kind of pretreatment unit checked for lupus cell - Google Patents

A kind of pretreatment unit checked for lupus cell Download PDF

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Publication number
CN204188442U
CN204188442U CN201420719231.3U CN201420719231U CN204188442U CN 204188442 U CN204188442 U CN 204188442U CN 201420719231 U CN201420719231 U CN 201420719231U CN 204188442 U CN204188442 U CN 204188442U
Authority
CN
China
Prior art keywords
pretreatment unit
clot
motor
glass container
montant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201420719231.3U
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Chinese (zh)
Inventor
黄萍
杨铮
杨阳
岳波
王菁
杨麦贵
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Priority to CN201420719231.3U priority Critical patent/CN204188442U/en
Application granted granted Critical
Publication of CN204188442U publication Critical patent/CN204188442U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of pretreatment unit checked for lupus cell, it is characterized in that, described pretreatment unit at least comprises magnetic stir bar device and clot smashs sub-device to pieces; Described magnetic stir bar device comprises the pedestal that can provide rotating magnetic field, is held on the glass container for splendid attire clot of pedestal upper surface, and is placed in the magnetic stirrer of band in glass container; Described clot is smashed sub-device to pieces and is comprised base, is fixed on the first motor on base, is arranged on the cam on the output shaft of the first motor, be vertically fixed on the pole on base, is arranged on pole outer ring slidably sleeve pipe; Its lower end has been horizontally disposed with stationary shaft, stationary shaft is provided with the roller matched with cam; Sleeve upper end has been horizontally disposed with cantilever, and the free end of cantilever is provided with montant, and the lower end of montant is provided with stamping hammer; Described stamping hammer is relative with the opening of described glass container.

Description

A kind of pretreatment unit checked for lupus cell
Technical field
The utility model relates to cellular immunity biochemical test device, specifically discloses a kind of pretreatment unit checked for lupus cell.
Background technology
Lupus cell (LEC) inspection refers to and checks whether the LEC factor exists in vitro, is diagnosis connective tissue disease (CTD), especially the sick conventional method of systemic loupus erythematosus.Its principle is that the LEC factor (anti-nucleoprotein IgG antibody) in patient's blood is acted on cell, make nucleus enlargement, lose original chromatin, form the material of a kind of even structureless circle or oval smoke-like, this material is engulfed rear formation lupus cell by the Polymorphonuclear leucocyte of maturation.
Lupus cell inspection need be carried out in vitro, needs the formation manually facilitating lupus cell.Detection method conventional is at present whole blood coagulation method.In testing process, needing clot to be placed in dried and clean in vitro, with bamboo let or microslide, clot being smashed to pieces, except defibrinating.Above-mentioned steps is manual operations, not only bothers, and also likely destroys the normal cell in clot, brings error to testing result; And above-mentioned steps does not have standardization, human factor is easy to affect testing result.
Summary of the invention
For problems of the prior art, the purpose of this utility model is to provide a kind of pretreatment unit checked for lupus cell, and it is manual that this pretreatment unit utilizes machinery to replace, convenient and swift, do not damage cell, and can realize normalizing operation, testing result accurately and reliably.
In order to reach above object, the utility model is achieved by the following technical solutions.
For the pretreatment unit that lupus cell checks, it is characterized in that, described pretreatment unit at least comprises magnetic stir bar device and clot smashs sub-device to pieces;
Described magnetic stir bar device comprises the pedestal that can provide rotating magnetic field, is held on the glass container for splendid attire clot of pedestal upper surface, and is placed in the magnetic stirrer of band in glass container;
Described clot is smashed sub-device to pieces and is comprised base, is fixed on the first motor on base, is arranged on the cam on the output shaft of the first motor, be vertically fixed on the pole on base, is arranged on pole outer ring slidably sleeve pipe; Its lower end has been horizontally disposed with stationary shaft, stationary shaft is provided with the roller matched with cam; Sleeve upper end has been horizontally disposed with cantilever, and the free end of cantilever is provided with montant, and the lower end of montant is provided with stamping hammer;
Described stamping hammer is relative with the opening of described glass container.
Feature of the present utility model and further improvement are:
(1) described pedestal has housing, and housing bottom is provided with output shaft the second motor upwards, and the output shaft of described second motor has been horizontally disposed with bar permanent magnet.
(2) lower end of described montant is provided with disk, and disk lower end is provided with multiple stamping hammer.
(3) described montant is screw mandrel, and screw mandrel is threaded with the free end of described cantilever.
(4) described stamping hammer has hammer handle and smooth, spherical tup.
Principle of work of the present utility model is: during work, the the first electric machine rotation band moving cam being smashed to pieces sub-device by clot is rotated, and the roller of this cam and its lower end interacts, and realizes sleeve pipe and moves up and down, by being fixed on the stamping hammer on sleeve pipe cantilever, clot is smashed to pieces; Rotated by the second driven by motor bar permanent magnet in magnetic stir bar device pedestal, produce rotating magnetic field, drive stirrer in glass container to rotate, accelerate clot fragmentation, fibrin simultaneously in clot is wrapped on stirrer, realizes the object removing clot inner fibrin fast.In addition, by regulating the height of the adjustable stamping hammer of upper-lower position of montant, disk can fix multiple stamping hammer simultaneously, realizing the object accelerating clot fragmentation.
Advantage of the present utility model and beneficial effect as follows: (1) this pretreatment unit instead of original manual operations, alleviates manpower, improves work efficiency.(2) this pretreatment unit adopts mechanically actuated, and operation can standardization, and eliminate the impact of human factor largely, testing result more accurately and reliably, and makes the testing result of parallel control experiment have more comparability.(3) to smash dynamics to pieces moderate for this pretreatment unit, smashs tup to pieces smooth, alleviate the destruction to clot inner cell largely, ensure that the accurate of testing result.(4) while stirrer plays the effect of stirring clot in this pretreatment unit, the fibrin in clot can be made to be wound around thereon, realize removing fibrinous object fast.
Accompanying drawing explanation
Fig. 1 is a kind of pretreatment unit schematic diagram checked for lupus cell of the present utility model.
Be labeled as in figure: 1, pedestal, 2, glass container, 3, stirrer, 4, the second motor, 5, bar permanent magnet, 6, clot, 7, base, 8, pole, 9, sleeve pipe, 10, stamping hammer, 11, cantilever, 12, stationary shaft, 13, roller, the 14, first motor, 15, cam, 16, disk, 17, montant, 18, nut.
Embodiment
Below in conjunction with specific embodiments and the drawings, the utility model is further explained, but the utility model is not limited thereto embodiment.
With reference to Fig. 1, be a kind of pretreatment unit checked for lupus cell of the present utility model, comprise magnetic stir bar device and clot smashs sub-device to pieces.
Wherein, magnetic stir bar device comprises the pedestal 1 that can provide rotating magnetic field, is held on the glass container 2 for splendid attire clot of pedestal 1 upper surface, and is placed in the stirrer 3 of the magnetic bar shaped of band in glass container 2.
This glass container 2 is test tube.This pedestal 1 has housing, and this housing is nonmagnetic substance, and the output shaft that housing bottom is provided with output shaft the second motor 4, second motor 4 has upwards been horizontally disposed with bar permanent magnet 5.
Wherein, clot is smashed sub-device to pieces and is comprised base 7, is fixed on the first motor 14 on base 7, is arranged on the cam 15 on the output shaft of the first motor 14, be vertically fixed on the pole 8 on base, is arranged on pole outer ring slidably sleeve pipe 9.
Sleeve pipe 9 lower end has been horizontally disposed with stationary shaft 12, stationary shaft 12 is provided with the roller 13 matched with cam 15; Sleeve upper end has been horizontally disposed with cantilever 11, and the free end of cantilever 11 is provided with montant 17, and this montant 17 is screw mandrel, and screw mandrel is fixed by nut 18 through the perforate on the free end of cantilever; The lower end of screw mandrel is provided with disk 16, is connected by nut.Disk lower end is provided with multiple stamping hammer 10, and stamping hammer 10 has hammer handle and smooth, spherical tup.Stamping hammer 10 is relative with the opening of glass container 2.
The assembling process of the pretreatment unit for lupus cell inspection of the present embodiment is as follows.
First, the first motor clot being smashed to pieces sub-device is placed on base 7, by installing other table tops additional to regulate motor height, and at motor output end stationary cam 15.The stationary shaft 12 of sleeve pipe 9 lower end and roller 13 are fixed, and is enclosed within outside pole 8, make contacting of roller 13 and cam 15.
Secondly, be fixed on by the hammer handle of 3 stamping hammers 10 on disk 16, tup down.Be fixed on by screw mandrel on disk 16, the cantilever 11 of screw mandrel and sleeve pipe 9 upper end is fixed together by recycling nut 18.By the position adjustments screw mandrel height of setting nut 18 to correct position,
Finally, clot 6 to be smashed to pieces is contained in glass container 2, fixes with test tube clamp 19, be placed in magnetic stir bar device pedestal 1 upper face center, and put into stirrer 3 in glass container 2.The position of adjustment pedestal 1, makes immediately below stamping hammer 10 tup facing to clot 6 to be smashed to pieces.
The use procedure of the pretreatment unit for lupus cell inspection of the present embodiment is as follows.
Open the first motor 14 that clot smashs sub-device to pieces, band moving cam 15 rotates, and cam 15 contacts with the roller 13 of sleeve pipe 9 lower end, under the cooperation of cam 15 and roller 13, sleeve pipe 9 moves up and down thereupon, and then 3 stamping hammers 10 be arranged on below cantilever 11 are moved up and down, and is smashed to pieces by clot 6.
Meanwhile, open magnetic stir bar device, the second motor 4 in pedestal 1 drives permanent magnet 5 to rotate, and produces rotating magnetic field, drives stirrer 3 in glass container to rotate, accelerates clot 6 fragmentation.In broken clot 6, water-fast fibrin is under agitation wrapped on stirrer 3, treat that clot 6 is completely broken, and fibrin is all wrapped in after on stirrer 3, close the power supply of pretreatment unit, stop smashing to pieces and rotating, throw away the stirrer 3 in container, realize the object removing clot inner fibrin fast.
Although be described embodiment of the present utility model above, the utility model is not limited to above-mentioned specific embodiments, and above-mentioned specific embodiments is only schematic, guiding, instead of restrictive.Those of ordinary skill in the art is under the enlightenment of this instructions, and when not departing from the scope that the utility model claim is protected, can also make a variety of forms, these all belong to the row of the utility model protection.

Claims (5)

1., for the pretreatment unit that lupus cell checks, it is characterized in that, described pretreatment unit at least comprises magnetic stir bar device and clot smashs sub-device to pieces;
Described magnetic stir bar device comprises the pedestal that can provide rotating magnetic field, is held on the glass container for splendid attire clot of pedestal upper surface, and is placed in the magnetic stirrer of band in glass container;
Described clot is smashed sub-device to pieces and is comprised base, is fixed on the first motor on base, is arranged on the cam on the output shaft of the first motor, be vertically fixed on the pole on base, is arranged on pole outer ring slidably sleeve pipe; Its lower end has been horizontally disposed with stationary shaft, stationary shaft is provided with the roller matched with cam; Sleeve upper end has been horizontally disposed with cantilever, and the free end of cantilever is provided with montant, and the lower end of montant is provided with stamping hammer;
Described stamping hammer is relative with the opening of described glass container.
2. the pretreatment unit checked for lupus cell according to claim 1, it is characterized in that, described pedestal has housing, and housing bottom is provided with output shaft the second motor upwards, and the output shaft of described second motor has been horizontally disposed with bar permanent magnet.
3. the pretreatment unit checked for lupus cell according to claim 1, it is characterized in that, the lower end of described montant is provided with disk, and disk lower end is provided with multiple stamping hammer.
4. the pretreatment unit checked for lupus cell according to claim 1, it is characterized in that, described montant is screw mandrel, and screw mandrel is threaded with the free end of described cantilever.
5. the pretreatment unit checked for lupus cell according to claim 1, it is characterized in that, described stamping hammer has hammer handle and smooth, spherical tup.
CN201420719231.3U 2014-11-25 2014-11-25 A kind of pretreatment unit checked for lupus cell Expired - Fee Related CN204188442U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420719231.3U CN204188442U (en) 2014-11-25 2014-11-25 A kind of pretreatment unit checked for lupus cell

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420719231.3U CN204188442U (en) 2014-11-25 2014-11-25 A kind of pretreatment unit checked for lupus cell

Publications (1)

Publication Number Publication Date
CN204188442U true CN204188442U (en) 2015-03-04

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CN (1) CN204188442U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109154542A (en) * 2016-03-17 2019-01-04 Sk电信有限公社 Biological sample pre-processing device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109154542A (en) * 2016-03-17 2019-01-04 Sk电信有限公社 Biological sample pre-processing device

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150304

Termination date: 20151125