CN202761829U - Stem cell transplantation helix electrode used for ventriculus dexter - Google Patents
Stem cell transplantation helix electrode used for ventriculus dexter Download PDFInfo
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- CN202761829U CN202761829U CN2012204877752U CN201220487775U CN202761829U CN 202761829 U CN202761829 U CN 202761829U CN 2012204877752 U CN2012204877752 U CN 2012204877752U CN 201220487775 U CN201220487775 U CN 201220487775U CN 202761829 U CN202761829 U CN 202761829U
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- stem cell
- cell transplantation
- electrode
- polyurethane tube
- right ventricle
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Abstract
The utility model discloses a stem cell transplantation helix electrode used for a ventriculus dexter. The stem cell transplantation helix electrode used for the ventriculus dexter comprises a box-shaped shell body (1), a keeping sheath pipe (2), a polyurethane pipe (3) and a stem cell injection electrode (4), the keeping sheath pipe (2) is fixedly connected with the box-shaped shell body (1), the polyurethane pipe (3) is arranged in the keeping sheath pipe (2), and the stem cell injection electrode (4) is arranged in the polyurethane pipe (3). Four metal joints (5) are arranged at the head end of the polyurethane pipe (3), four perceiving electrodes (6) are inlaid at the tail end of the polyurethane pipe (3), and the four metal joints (5) are connected with the four perceiving electrodes (6) through wire leads. The stem cell injection electrode (4) is of hollow structure, a helix shaped electrode (7) is arranged at the tail end of the stem cell injection electrode (4) and of hollow structure, and through holes (8) are arranged in the helix shaped electrode (7). The stem cell transplantation helix electrode used for the ventriculus dexter can be kept in a body for a long time, and multi-time and multi-point operation can be conducted when an implantation point is chosen. Meanwhile, the stem cell transplantation helix electrode used for the ventriculus dexter can hold large amount of liquid (cells), and the contacting area of the stem cell transplantation helix electrode used for the ventriculus dexter and cardiac muscle is large, so that probability of success of stem cell transplantation is high. In addition, the stem cell transplantation helix electrode used for the ventriculus dexter has the advantages of being little in damage on vessel, and low in probability of massive hemorrhage.
Description
Technical field
This utility model relates to a kind of screw electrode, and particularly a kind of stem cell transplantation screw electrode for right ventricle belongs to medical instruments field.
Background technology
Arrival along with aging society, the sickness rate of cardiovascular disease increases year by year, myocardial cell, vascular endothelial cell acute or that chronic cardiovascular disease causes are lost and are caused cardiac insufficiency, bring thus disable, mortality rate increases year by year, bring great burden to society, China has the patient above 700000 to die from coronary heart disease every year.How saving or substituting impaired myocardial cell, blood vessel etc. is a task in the urgent need to address.
Previously the biological nature of stem cell (stem cell) regenerating tissues has been found in research, possesses the tremendous potential for the treatment of human diseases.Although the stem cell basic research has obtained larger progress, under present condition, cardiac stem cells is transplanted the clinical extensive practice of distance and is also had larger distance.
Present effect preferably transplanting mode is the endocardium injection method: transplanting through endocardium is under the guiding of myocardium electromechanical mapping equipment, the conduit that carries entry needle passes to drive in the wrong direction after the aortic valve and enters ventricular chamber, determine ishemic part at endocardial surface according to current potential, then with stem cell to be expelled in the cardiac muscle perpendicular to endocardial direction.World wide uses most often Noga system at present, and this system is developed by Johnson Co., and at present domestic also have part scientific research institution and clinical part to introduce this system, and this system is divided into two parts: myocardium electromechanical mapping equipment and injection catheter.
Although the Noga systematic comparison is advanced, but this system also exists and remains improved part: 1, the Noga system pass is the tremulous pulse operation, can not be retained in body, can only single operation (can not many time points injections), if many time points are transplanted, need Repeated Operation, expense large (comprising Noga stem cell syringe and surgery cost), to patient's injury also large (tremulous pulse repeatedly punctures); 2, owing to being that single approach and Noga stem cell syringe tail end are the entry needle head, the transplanted cells amount that therefore comprises liquid is restricted, and the probability of success of stem cell transplantation is lower; 3, the tremulous pulse approach is not suitable in a short time repeatedly stem cell transplantation (stem cell transplantation window relative narrower behind the myocardial infarction, general transplant operation need to be carried out in January after myocardial infarction occurs, and have the massive hemorrhage probability, endarterium is formed infringement infarcted region this moment complete fibrosis also).
The utility model content
The purpose of this utility model is, a kind of stem cell transplantation screw electrode for right ventricle is provided, and it can keep in vivo for a long time, can be repeatedly when select implanting point, multipoint operation.And it can hold more liquid (cell), and is large with the contact surface of cardiac muscle, makes the probability of success of stem cell transplantation higher.In addition it also have blood vessel injury little, the advantage that the massive hemorrhage probability is lower.
The technical solution of the utility model: a kind of stem cell transplantation screw electrode for right ventricle, comprise box-like housing, reservation sheath pipe, polyurethane tube and stem cell injection electrodes, keeping the sheath pipe is fixedly connected with box-like housing, polyurethane tube is located at and is kept in the sheath pipe, and the stem cell injection electrodes is located in the polyurethane tube; The head end of polyurethane tube is provided with 4 metal joints, and tail end is inlaid with 4 sensing electrodes, and 4 metal joints are connected with 4 sensing electrodes by wire; The stem cell injection electrodes is hollow structure, and its tail end is provided with spiral electrode, and spiral electrode is hollow structure, and spiral electrode is provided with through hole.Polyurethane tube plays a supportive role, and the compatibility of polyurethane is good; Keep the sheath pipe during operation as operation path, polyurethane tube carries out operation technique by keeping the sheath pipe; 3 are used for perception intracavity current potential in 4 sensing electrodes, and 1 is used for the perception current potential.Sensing electrode positions according to current potential and changes of magnetic field; The tail end of whole stem cell transplantation screw electrode is flexible translation-angle design.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the head end of stem cell injection electrodes is higher than the head end of polyurethane tube.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the height of described box-like housing is 8CM, and width is 8CM, and the top is provided with the first capping with matching, and box-like housing and the first capping are threaded connection.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the wall thickness of polyurethane tube is 1.5F.At 1F=0.33mm medically, F is conventional unit.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the internal diameter of stem cell injection electrodes is 1F, wall thickness is 1F.
Aforesaid this stem cell transplantation screw electrode for right ventricle, polyurethane tube and stem cell injection electrodes all adopt 316L shaped steel to make.Except adopting 316L shaped steel, can also adopt other can play the alloy of electrical signal conduction and the effect of stem cell injection canal.Because 316 L-type steel have price advantage, so the preferred 316L shaped steel of this case.
Aforesaid this stem cell transplantation screw electrode for right ventricle, described sensing electrode is ring-type.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the aperture of described through hole are 30 μ m～50 μ m, and the distance between 2 through holes of arbitrary neighborhood is 50 μ m.Through hole on the spiral electrode is to adopt the mode of laser boring to make.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the head end of polyurethane tube are provided with the second capping that cooperates with it, and the second capping and polyurethane tube are threaded connection.
Aforesaid this stem cell transplantation screw electrode for right ventricle, the head end of described stem cell injection electrodes is provided with four fence gate plastic cement cappings.
Compared with prior art, this utility model is provided with reservation sheath pipe can be kept in vivo for a long time, realizes multiple injection, and surgery cost is relatively low, and the patient is injured little.
Stem cell injection electrodes tail end of the present utility model is helical design, can hold more liquid (cell), can effectively increase contact surface with cardiac muscle owing to being provided with through hole at spiral electrode, be conducive to stem cell and permeate in the cardiac muscular tissue, Effective Raise the probability of success of stem cell transplantation.
Because this utility model can be retained in body for a long time, generally can be retained in body January, little to the blood vessel injury, effectively reduce the probability of massive hemorrhage.
Description of drawings
Fig. 1 is structural representation of the present utility model.
The box-like housing of being labeled as in the accompanying drawing: 1-, 2-keeps sheath pipe, 3-polyurethane tube, 4-stem cell injection electrodes, 5-metal joint, 6-sensing electrode, 7-spiral electrode, 8-through hole, 9-the first capping, 10-four fence gate plastic cement cappings, 11-the second capping.
The specific embodiment
The utility model is described in further detail below in conjunction with drawings and Examples, but not as the foundation of this utility model being done any restriction.
The head end of stem cell injection electrodes 4 is higher than the head end of polyurethane tube 3.The height of box-like housing 1 is 8CM, and width is 8CM, and the top is provided with the first capping 9 with matching, and box-like housing 1 and the first capping 9 are threaded connection.The wall thickness of polyurethane tube 3 is 1.5F.The internal diameter of stem cell injection electrodes 4 is 1F, and wall thickness is 1F.Polyurethane tube 3 and stem cell injection electrodes 4 all adopt 316L shaped steel to make.The head end of stem cell injection electrodes 4 is provided with four fence gate plastic cement cappings 10.The head end of polyurethane tube 3 is provided with the second capping 11, the second cappings 11 that cooperate with it and is threaded connection with polyurethane tube 3.
The head end of stem cell injection electrodes 4 is higher than the head end of polyurethane tube 3.The height of described box-like housing 1 is 8CM, and width is 8CM, and the top is provided with the first capping 9 with matching, and box-like housing 1 and the first capping 9 are threaded connection.The wall thickness of polyurethane tube 3 is 1.5F.The internal diameter of stem cell injection electrodes 4 is 1F, and wall thickness is 1F.Polyurethane tube 3 and stem cell injection electrodes 4 all adopt 316L shaped steel to make.The head end of stem cell injection electrodes 4 is provided with four fence gate plastic cement cappings 10.The head end of polyurethane tube 3 is provided with the second capping 11, the second cappings 11 that cooperate with it and is threaded connection with polyurethane tube 3.
The head end of stem cell injection electrodes 4 is higher than the head end of polyurethane tube 3.The height of described box-like housing 1 is 8CM, and width is 8CM, and the top is provided with the first capping 9 with matching, and box-like housing 1 and the first capping 9 are threaded connection.The wall thickness of polyurethane tube 3 is 1.5F.The internal diameter of stem cell injection electrodes 4 is 1F, and wall thickness is 1F.Polyurethane tube 3 and stem cell injection electrodes 4 all adopt 316L shaped steel to make.The head end of stem cell injection electrodes 4 is provided with four fence gate plastic cement cappings 10.The head end of polyurethane tube 3 is provided with the second capping 11, the second cappings 11 that cooperate with it and is threaded connection with polyurethane tube 3.
In addition, whole stem cell transplantation screw electrode tail end be the design of flexible translation-angle.
Using method of the present utility model: the right internal jugular vein that at first punctures, then the reservation sheath pipe 2 of implantation 6F implants polyurethane tube 3 and stem cell injection electrodes 4 to cardiac muscular tissue.At first external intercoil connection terminates to metal joint 5 one on magnetic navigation or the current potential navigation system and positions (can not pollute like this) to metal joint 5.After finish the location, implant spiral electrode 7 at corresponding position, then open four fence gate plastic cement cappings 10, be injected into stem cell suspension from the head end of stem cell injection electrodes 4, after the end, change the position and continue to transplant, transplant (generally can be 10-20 injection site) around the infarction marginal zone.After once transplanting end, suspended electrode is in right ventricle.Pull out intercoil connection, with the second capping 11 closed metal joints 5, use the head end of four fence gate plastic cement cappings sealing stem cell injection electrodes 4, annotate heparin, antibiotic liquid in box-like housing 1, and seal with the first capping 9.After each transplanting finishes, the ventilative wound closure of applying ointment or plaster of sterilizing of external.
Claims (10)
1. stem cell transplantation screw electrode that is used for right ventricle, it is characterized in that: comprise box-like housing (1), keep sheath pipe (2), polyurethane tube (3) and stem cell injection electrodes (4), keeping sheath pipe (2) is fixedly connected with box-like housing (1), polyurethane tube (3) is located at and is kept in the sheath pipe (2), and stem cell injection electrodes (4) is located in the polyurethane tube (3); The head end of polyurethane tube (3) is provided with 4 metal joints (5), and tail end is inlaid with 4 sensing electrodes (6), and 4 metal joints (5) are connected with 4 sensing electrodes (6) by wire; Stem cell injection electrodes (4) is hollow structure, and its tail end is provided with spiral electrode (7), and spiral electrode (7) is hollow structure, and spiral electrode (7) is provided with through hole (8).
2. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1, it is characterized in that: the head end of stem cell injection electrodes (4) is higher than the head end of polyurethane tube (3).
3. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1, it is characterized in that: the height of described box-like housing (1) is 8CM, width is 8CM, the top is provided with the first capping with matching (9), and box-like housing (1) is threaded connection with the first capping (9).
4. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1, it is characterized in that: the wall thickness of polyurethane tube (3) is 1.5F.
5. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1, it is characterized in that: the internal diameter of stem cell injection electrodes (4) is 1F, wall thickness is 1F.
6. according to claim 1 or 4 or 5 described a kind of stem cell transplantation screw electrodes for right ventricle, it is characterized in that: polyurethane tube (3) and stem cell injection electrodes (4) all adopt 316L shaped steel to make.
7. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1 is characterized in that: described sensing electrode (6) is ring-type.
8. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1, it is characterized in that: the aperture of described through hole (8) is 30 μ m～50 μ m, and the distance between 2 through holes of arbitrary neighborhood (8) is 50 μ m.
9. according to claim 1 or 8 described a kind of stem cell transplantation screw electrodes for right ventricle, it is characterized in that: the head end of polyurethane tube (3) is provided with the second capping (11) that cooperates with it, and the second capping (11) is threaded connection with polyurethane tube (3).
10. a kind of stem cell transplantation screw electrode for right ventricle according to claim 1, it is characterized in that: the head end of described stem cell injection electrodes (4) is provided with four fence gate plastic cement cappings (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012204877752U CN202761829U (en) | 2012-09-21 | 2012-09-21 | Stem cell transplantation helix electrode used for ventriculus dexter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012204877752U CN202761829U (en) | 2012-09-21 | 2012-09-21 | Stem cell transplantation helix electrode used for ventriculus dexter |
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| Publication Number | Publication Date |
|---|---|
| CN202761829U true CN202761829U (en) | 2013-03-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012204877752U Expired - Fee Related CN202761829U (en) | 2012-09-21 | 2012-09-21 | Stem cell transplantation helix electrode used for ventriculus dexter |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103494607A (en) * | 2013-09-29 | 2014-01-08 | 张开元 | Brain buried pipe medicine applying cannula capable of recording cell external electric potential |
| CN108742605A (en) * | 2018-06-19 | 2018-11-06 | 苏州修普诺斯医疗器械有限公司 | Mobile brain wave acquisition device with screw electrode |
-
2012
- 2012-09-21 CN CN2012204877752U patent/CN202761829U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103494607A (en) * | 2013-09-29 | 2014-01-08 | 张开元 | Brain buried pipe medicine applying cannula capable of recording cell external electric potential |
| CN103494607B (en) * | 2013-09-29 | 2016-03-02 | 中国人民解放军第三军医大学 | A kind of brain administration pipe laying sleeve pipe recording extracellular potential |
| CN108742605A (en) * | 2018-06-19 | 2018-11-06 | 苏州修普诺斯医疗器械有限公司 | Mobile brain wave acquisition device with screw electrode |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130306 Termination date: 20160921 |
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| CF01 | Termination of patent right due to non-payment of annual fee |