CN202568894U

CN202568894U - Preparation system of effervescent tablets

Info

Publication number: CN202568894U
Application number: CN 201220242722
Authority: CN
Inventors: 孙鹤鸣
Original assignee: SHENZHEN MCKIN INDUSTRIAL Co Ltd
Current assignee: SHENZHEN MCKIN INDUSTRIAL Co Ltd
Priority date: 2012-05-28
Filing date: 2012-05-28
Publication date: 2012-12-05
Anticipated expiration: 2022-05-28

Abstract

The utility model discloses a preparation system of effervescent tablets. The preparation system comprises a high-efficiency wet type granulator, a 20-mesh nylon net swing granule finishing machine, a 16-mesh nylon net swing granule finishing machine, a drying oven, a three-dimensional movement mixer and a tablet machine. The high-efficiency wet type granulator comprises a stirring chamber, a stirring paddle, a chopping knife and a discharging piston, wherein the stirring paddle and the chopping knife are both arranged in the stirring chamber which is provided with a discharging port, and the discharging piston is matched with the discharging port. The 20-mesh nylon net swing granule finishing machine and the 16-mesh nylon net swing granule finishing machine are connected with the discharging port respectively. The drying oven is connected with the 20-mesh nylon net swing granule finishing machine and the 16-mesh nylon net swing granule finishing machine respectively. The three-dimensional movement mixer is connected with the drying oven, and the tablet machine is connected with the three-dimensional movement mixer. The preparation system of the effervescent tablets prepares acid granules through wet type granulation and alkali granules through nonaqueous granulation. Therefore, compared with the wet type granulation, the preparation system is simple in operation; and compared with the nonaqueous granulation, the preparation system is low in cost.

Description

The preparation system of effervescent tablet

Technical field

This utility model relates to a kind of preparation system of effervescent tablet.

Background technology

Effervescent tablet is meant and contains sodium bicarbonate and organic acid, meet that water can produce great amount of carbon dioxide and rapidly dissolving be tablet (preparation and the research overview of edible effervescent tablet, place fan chrysanthemum, Mao Zhifang etc., Chinese tea processing 2008, (2): 20-23) of effervescent shape.

Traditional effervescent tablet preparation system adopts wet granulation or non-water to granulate usually.Wet granulation is granulated acid and/or alkali respectively with aqueous binders, dry respectively, mix homogeneously carries out tabletting before tabletting.Contact sour, alkali that wet granulation has been avoided prevents acid-base reaction takes place in the operating process, helps stability of formulation.Component was granulated with on-aqueous liquid (like isopropyl alcohol, dehydrated alcohol) during non-water was granulated and will be write out a prescription.Non-water is granulated simple than wet granulation, but non-aqueous adhesive price is a little more than wet granulation.

The wet granulation operation is comparatively complicated, the employing nonaqueous solvent but not water is granulated, and relative cost is higher.

The utility model content

Based on this, be necessary to provide the preparation system of the comparatively simple and lower-cost effervescent tablet of a kind of operation.

A kind of preparation system of effervescent tablet comprises:

Efficient wet granulator; Be used for the wet granulation granulates; And non-water granulation preparation alkali granule, comprising teeter chamber, stirring paddle, shredder bar and discharge piston, said stirring paddle and shredder bar all are arranged in the said teeter chamber; Said teeter chamber is provided with discharging opening, and said discharge piston and said discharging opening are complementary;

20 order nylon wires wave pelletizing machine and 16 order nylon wires wave pelletizing machine; Said 20 order nylon wires wave pelletizing machine and wave pelletizing machine with 16 order nylon wires and link to each other with said discharging opening respectively; Said 20 order nylon wires wave pelletizing machine and form granulates, and said 16 order nylon wires wave pelletizing machine and form the alkali granule;

Baking oven waves pelletizing machine with said 20 order nylon wires respectively and waves pelletizing machine with 16 order nylon wires and link to each other granulates and alkali granule that dry respectively said efficient wet granulator makes;

Three-dimensional motion mixer links to each other with said baking oven, exsiccant granulates and alkali granule and mix lubricant that said baking oven is obtained; And

Tablet machine links to each other with said three-dimensional motion mixer, and the mixture tabletting that said three-dimensional motion mixer is obtained obtains effervescent tablet.

In one embodiment, said efficient wet granulator also comprised material screen, and the said material screen of crossing links to each other with said teeter chamber.

In one embodiment, said material screen excessively is 100 mesh sieves.

The preparation system of this effervescent tablet is granulated through wet granulation granulates and non-water and prepared the alkali granule, and is comparatively simple with respect to the wet granulation operation, lower with respect to non-water granulation cost.

Description of drawings

Fig. 1 is the structural representation of preparation system of the effervescent tablet of an embodiment.

The specific embodiment

For the ease of understanding this utility model, will more comprehensively describe this utility model with reference to relevant drawings below.Provided the preferred embodiment of this utility model in the accompanying drawing.But this utility model can be realized with many different forms, be not limited to embodiment described herein.On the contrary, provide the purpose of these embodiment be make the understanding of the disclosure of this utility model comprehensively thorough more.

The preparation system of a kind of effervescent tablet of an embodiment as shown in Figure 1 comprises: efficient wet granulator, 20 order nylon wires wave pelletizing machine 20,16 order nylon wires and wave pelletizing machine 30, baking oven 40, three-dimensional motion mixer 50 and tablet machine 60.

Efficient wet granulator is used for the wet granulation granulates, and non-water granulation preparation alkali granule.

Efficient wet granulator comprises teeter chamber 12, stirring paddle 14, shredder bar 16 and discharge piston 18.Stirring paddle 14 all is arranged in the teeter chamber 12 with shredder bar 16, and teeter chamber 12 is provided with discharging opening 17, and discharge piston 17 is complementary with discharging opening 16.

20 order nylon wires wave pelletizing machine 20 and wave pelletizing machine 30 with 16 order nylon wires and link to each other with discharging opening 17 respectively.20 order nylon wires wave pelletizing machine 20 and are used to form granulates, and 16 order nylon wires wave pelletizing machine 30 and are used to form the alkali granule.

Baking oven 40 waves pelletizing machine with said 20 order nylon wires respectively and waves pelletizing machine with 16 order nylon wires and link to each other, and is used for granulates and alkali granule that dry respectively said efficient wet granulator makes;

Three-dimensional motion mixer 50 links to each other with said baking oven, is used for exsiccant granulates and alkali granule and mix lubricant that said baking oven is obtained; And

Tablet machine 60 links to each other with said three-dimensional motion mixer, and the mixture tabletting that said three-dimensional motion mixer is obtained obtains effervescent tablet.

Efficient wet granulator also comprised material screen 19, crossed material screen 19 and linked to each other with teeter chamber 12.

Cross the raw material that material screen 19 will prepare effervescent tablet and sieve, the raw material after sieving is put into teeter chamber 12.

In this embodiment, crossing material screen 19 is that 100 orders are crossed material screen.

In a preferred embodiment, the preparation system of effervescent tablet comprises that also 18 order nylon wires wave pelletizing machine.18 order nylon wires wave pelletizing machine and link to each other with three-dimensional motion mixer 50 with baking oven 40 respectively, are used for dried granulates and alkali granule are carried out granulate.

In a preferred embodiment, the preparation system of effervescent tablet also comprises trough-type mixture machine.The raw material that trough-type mixture machine will prepare effervescent tablet mixes.

Be example with the preparation vitamin C effervescent tablet below, the preparation system of above-mentioned effervescent tablet is further specified.

Sieve: with sodium bicarbonate, citric acid, starch respectively material screen 19, back material preserve separately will sieve.

Granulate:

(1) dried mixing: vitamin C and citric acid are put in the trough-type mixture machine, and setting dried doing time is 10 minutes, does and mixes.Sodium bicarbonate and steviol glycosides are carried out same operation.

(2) antacid granule: adopting efficient wet granulator, is that 12% starch slurry, vitamin C and citric acid are put in the teeter chamber 12 with the mass fraction for preparing, and setting the wet mixing time is 85 seconds; Stirring paddle 14 rotating speeds are made as I speed, and shredder bar 16 rotating speeds are made as II speed, carry out wet mixing; Wet mixing finishes, and opens discharge piston 18, opens stirring arm 14; Discharging, 20 order nylon wires wave granulation machine 20 and process granulates.

(3) system alkali granule: adopt efficient wet granulator, with putting in the ethanol for preparing, sodium bicarbonate and the steviol glycosides in the teeter chamber 12, setting the wet mixing time is 85 seconds; Stirring paddle 14 rotating speeds are made as I speed, and shredder bar 16 rotating speeds are made as II speed, carry out wet mixing; Wet mixing finishes, and opens discharge piston 18, opens stirring arm 14; Discharging, 16 order nylon wires wave granulation machine 30 and process the alkali granule.

Dry: as granulates and alkali granule to be respectively charged in the drip pan, to put into TG-Z-III type heated-air circulation oven 40 and carry out drying.Baking temperature is 50 ℃, and be 4.5 hours drying time.Whenever to carry out stirring in the dry run at a distance from 1 hour.

Granulate: dried granulates and alkali granule are waved granulation machine with 18 order nylon wires respectively carry out granulate.

Mix: exsiccant granulates behind the granulate and alkali granule are poured in the SYH-800 type three-dimensional motion mixer 50, added magnesium stearate simultaneously and mix, incorporation time is 10 minutes.

Tabletting: punch die is installed, is set operational factor, prepare tabletting (punch die specification: 15.5mm * 8.5mm scrobicula does not have the word abnormal shape and dashes) according to calculating sheet recanalization tablet machine 60.

The above embodiment has only expressed one or more embodiments of this utility model, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to this utility model claim.Should be pointed out that for the person of ordinary skill of the art under the prerequisite that does not break away from this utility model design, can also make some distortion and improvement, these all belong to the protection domain of this utility model.Therefore, the protection domain of this utility model patent should be as the criterion with accompanying claims.

Claims

1. the preparation system of an effervescent tablet is characterized in that, comprising:

2. the preparation system of effervescent tablet according to claim 1 is characterized in that, said efficient wet granulator also comprised material screen, and the said material screen of crossing links to each other with said teeter chamber.

3. the preparation system of effervescent tablet according to claim 1 is characterized in that, said material screen excessively is 100 mesh sieves.