CN202193792U - Small-sized cell culture bottle roller - Google Patents
Small-sized cell culture bottle roller Download PDFInfo
- Publication number
- CN202193792U CN202193792U CN 201120241674 CN201120241674U CN202193792U CN 202193792 U CN202193792 U CN 202193792U CN 201120241674 CN201120241674 CN 201120241674 CN 201120241674 U CN201120241674 U CN 201120241674U CN 202193792 U CN202193792 U CN 202193792U
- Authority
- CN
- China
- Prior art keywords
- cell culture
- bottle
- bottle roller
- cell
- rotating shafts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
- C12M27/12—Roller bottles; Roller tubes
Abstract
The utility model discloses a small-sized cell culture bottle roller, which relates to a device used for preparation production and cell culture of vaccines, antibodies, stem cells and the like. The small-sized cell culture bottle roller comprises a control cabinet, bottle roller rotating shafts for cell culture, a belt transmission device and a rack, wherein the control cabinet is arranged at the lower part of the rack and is internally provided with a motor, a power supply and a control panel; at least a row of bottle roller rotating shafts for cell culture are arranged on the rack; at least two bottle roller rotating shafts for cell culture are arranged in each row; the bottle roller rotating shafts for cell culture are arranged in parallel mutually; a cylindrical cell culture bottle is arranged above the part between the two adjacent bottle roller rotating shafts for cell culture in the same row; and a shaft head of each bottle roller rotating shaft for cell culture is connected with a rotating shaft of the motor in the control cabinet via the belt transmission device. The limit conditions in laboratory are adopted to quickly and effectively prepare needed cell expressive objects or cultivate relevant cells; therefore, the problems of time waste, labor waste and large loss of a traditional method can be effectively solved.
Description
Technical field
The utility model relates to technological field of biochemistry, is specifically related to preparations such as vaccine, antibody, stem cell and produces and the cell cultures equipment therefor.
Background technology
Conventional cell is cultivated and is used square vase, because the surface-area of each square vase probably has only 225cm
2, thereby no matter be for the small-scale preparation of various representations of cell or cell or for the research work of cell cultures, generally need tens or even tens square vases to cultivate, and also can spend great amount of time therebetween.Simultaneously owing to want the numerous square vase of operation amount, cannot say for sure potential pollution problem in the operating process, and the differentiation between cell batch.There is consuming time, consumption power in existing installation if prepare required cell expressing thing or turn out relevant cell, and cost is high, is prone to pollute, and can make cell the shortcoming of differentiation occur simultaneously.
The utility model content
The utility model provides a kind of minicell to cultivate and rolls a bottle machine, and the utility model utilizes the limited condition in laboratory, realizes fast and effeciently preparing required cell expressing thing or turning out relevant cell; Can effectively avoid time-consuming, the effort of traditional method, the big problem of loss.
For realizing goal of the invention, the utility model adopts following technical scheme: comprise that housing 1, cell cultures are with rolling bottle rotation axis 2, belt transmission 3 and frame 4; Housing 1 is installed on frame 4 bottoms, and motor, power supply and switchboard are installed in the housing 1; At least one row's cell cultures is installed with rolling bottle rotation axis 2 on frame 4; Each drains into rare two cell cultures with rolling bottle rotation axis 2; Cell cultures is arranged in parallel with rolling between bottle rotation axis 2, and two cell cultures adjacent with row are provided with a columniform Tissue Culture Flask with the top of rolling between bottle rotation axis 2; Each cell cultures connects the rotating shaft of motor in the housing 1 through belt transmission 3 with the spindle nose that rolls bottle rotation axis 2.
The utility model is that a small-sized cell cultures is rolled a bottle machine, and is economical and practical, can just satisfy a needed cell concentration of experiment level cell jar, is fit to experiment rank and pilot scale primary operation.
The utility model has solved traditional square vase cultivation and has taken time and effort to experiment level cell jar seed culture, and cost is high, is prone to pollute, and can make cell the differentiation problem occur simultaneously.The cell cultures that the utility model provides is rolled a bottle machine, can effective intensive culturing cell, save incubation time, energy and cost, and can farthest reduce the differentiation between cell batch simultaneously, reduce Pollution risk.The surface-area that rolls bottle is 725cm2, approximately is 3.7 times of T225 square vase, and 2-4 cell concentration that rolls bottle just can satisfy an experiment level cell jar inoculation demand.
Description of drawings
Fig. 1 is the utility model stereographic map;
Fig. 2 is the utility model front view;
Fig. 3 is the side-view of Fig. 1.
Nomenclature among the figure: 1, housing (in be provided with motor, power supply, switchboard); 2, cell cultures is with rolling a bottle rotation axis; 3, belt transmission; 4, frame.
Embodiment
Shown in Fig. 1-3, minicell is cultivated and is rolled a bottle machine, comprises that housing 1, cell cultures are with rolling bottle rotation axis 2, belt transmission 3 and frame 4; Housing 1 is installed on frame 4 bottoms, and motor, power supply and switchboard are installed in the housing 1; At least one row's cell cultures is installed with rolling bottle rotation axis 2 on frame 4; Each drains into rare two cell cultures with rolling bottle rotation axis 2; Cell cultures is arranged in parallel with rolling between bottle rotation axis 2, and two cell cultures adjacent with row are provided with a columniform Tissue Culture Flask with the top of rolling between bottle rotation axis 2; Each cell cultures connects the rotating shaft of motor in the housing 1 through belt transmission 3 with the spindle nose that rolls bottle rotation axis 2.
The utility model centers on the intensive culture apparatus of cell before jar cultivation on the cell first, has invented this kind of minicell and has cultivated bottle machine that rolls.This rolls bottle machine can effective intensive culturing cell, saves incubation time, energy and cost, can farthest reduce the differentiation between cell batch simultaneously.Generally the maximum surface-area like the commercialization square vase is 225cm
2(T225 square vase), cell roll bottle the chances are 725cm
2, an experiment level cell jar seed dose needs tens square vases to cultivate.A bottle machine is rolled in employing, and the individual bottle that rolls of 2-4 just can satisfy the inoculation demand, therefore can improve the working efficiency of cell cultures greatly, reduces Pollution risk, reduces and operates the cell differentiation that causes.This machine mainly is intended for middle-size and small-size pharmaceutical factory, biological enterprise, and a grade cell jar seed culture operation experimentizes.
Roll bottle machine and drive and roll bottle and constantly removed through rotation through the refuse that rotation produces cellular metabolism, new nutritive ingredient constantly moves to cell peripheral, has quickened the absorption of oxygen, and CO gets rid of efficient.Therefore, cultivation is compared with the immobilized square vase, rolls a bottle dynamic cultivation and can improve the growth rate of cell and the secretion rate of some antibody.This practical minicell rolls a bottle machine, minimumly can design 2 bottle positions, is very suitable for breadboard conventional cell cultures, because advantages of small volume can be matched with any incubator rapidly.
The square vase that the utility model cultivate to use with respect to conventional cell, cell cultures roll bottle facility has convenient, safe, advantage fast; And rolling a bottle machine with respect to pilot scale/type of production with tens or even tens bottle positions, this minicell is cultivated and is rolled bottle facility and take up room for a short time, experimental situation is on every side required low, is convenient to the advantage of supporting cell culture incubator.
What should explain at last is: obviously, the foregoing description only be for explain clearly that the utility model does for example, and be not qualification to embodiment.For the those of ordinary skill in affiliated field, can also make other multi-form variation or change on the basis of the above description.Here need not also can't give exhaustive to all embodiments.And conspicuous variation of being amplified out thus or change still are among the protection domain of the utility model.
Claims (1)
1. minicell is cultivated and is rolled a bottle machine, it is characterized in that, comprises that housing (1), cell cultures are with rolling a bottle rotation axis (2), belt transmission (3) and frame (4); Housing (1) is installed on frame (4) bottom, and housing is equipped with motor, power supply and switchboard in (1); At least one row's cell cultures is installed with rolling a bottle rotation axis (2) on frame (4); Each drains into rare two cell cultures with rolling a bottle rotation axis (2); Cell cultures is arranged in parallel with rolling between bottle rotation axis (2), and two cell cultures adjacent with row are provided with a columniform Tissue Culture Flask with the top of rolling between bottle rotation axis (2); Each cell cultures connects the rotating shaft of the interior motor of housing (1) through belt transmission (3) with the spindle nose that rolls a bottle rotation axis (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120241674 CN202193792U (en) | 2011-07-11 | 2011-07-11 | Small-sized cell culture bottle roller |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120241674 CN202193792U (en) | 2011-07-11 | 2011-07-11 | Small-sized cell culture bottle roller |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202193792U true CN202193792U (en) | 2012-04-18 |
Family
ID=45948713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120241674 Expired - Fee Related CN202193792U (en) | 2011-07-11 | 2011-07-11 | Small-sized cell culture bottle roller |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202193792U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105794702A (en) * | 2016-04-29 | 2016-07-27 | 辽宁省海洋水产科学研究院 | Jellyfish acetabulum culture device and use method thereof |
| CN107723239A (en) * | 2017-11-23 | 2018-02-23 | 深圳北科赛动生物机器人有限公司 | High flux roller bottle apparatus |
-
2011
- 2011-07-11 CN CN 201120241674 patent/CN202193792U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105794702A (en) * | 2016-04-29 | 2016-07-27 | 辽宁省海洋水产科学研究院 | Jellyfish acetabulum culture device and use method thereof |
| CN105794702B (en) * | 2016-04-29 | 2018-07-10 | 辽宁省海洋水产科学研究院 | A kind of jellyfish acetabulum culture apparatus and its application method |
| CN107723239A (en) * | 2017-11-23 | 2018-02-23 | 深圳北科赛动生物机器人有限公司 | High flux roller bottle apparatus |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120418 Termination date: 20140711 |
|
| EXPY | Termination of patent right or utility model |