CN201823545U - Multichannel pipetting device - Google Patents

Multichannel pipetting device Download PDF

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Publication number
CN201823545U
CN201823545U CN2010205777023U CN201020577702U CN201823545U CN 201823545 U CN201823545 U CN 201823545U CN 2010205777023 U CN2010205777023 U CN 2010205777023U CN 201020577702 U CN201020577702 U CN 201020577702U CN 201823545 U CN201823545 U CN 201823545U
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CN
China
Prior art keywords
liquid
transposition arrangement
arrangement according
transfering device
channeled transposition
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Expired - Fee Related
Application number
CN2010205777023U
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Chinese (zh)
Inventor
周宝津
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BGI Shenzhen Co Ltd
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BGI Shenzhen Co Ltd
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Priority to CN2010205777023U priority Critical patent/CN201823545U/en
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Publication of CN201823545U publication Critical patent/CN201823545U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model discloses a multichannel pipetting device comprising a frame body (3) and at least two pipetting devices (5), wherein the frame body is internally provided with a support mechanism (4); the at least two pipetting devices (5) are fixed on the support mechanism; and the support mechanism (4) is a stretching mechanism. The technical effect is as follows: by changing the distance between every two of multiple channels in a unified manner, the pipetting between different multichannel sample-loading containers is realized; and the multichannel pipetting device is convenient and flexible to use, assemble and disassemble.

Description

Multi-channeled transposition arrangement
Technical field
The utility model relates to a kind of liquid-transfering device, the adjustable multi-channeled transposition arrangement of distance between particularly a kind of each passage.
Background technology
Liquid-transfering device is widely used in biological experiments such as biochemistry, molecule, cell, and its major function is exactly that liquid with certain volume shifts.In existing widely used liquid-transfering device, have multichannelly, have single passly, also have manually, also there is electronics automatic.In multi-channeled transposition arrangement, the volley of rifle fire is widely used, and it can the disposable liquid that pipettes the multichannel equal volume accurately.
Chinese patent 200420093039.4 has been announced a kind of multi-channeled transposition arrangement, this liquid-transfering device comprises several liquid-transfering devices and is used for fixing the framework of described liquid-transfering device, described liquid-transfering device comprises syringe needle, syringe and push rod, described syringe needle closely is connected with syringe, and described pushing rod sleeve is located in the described syringe; The top of described framework is provided with pressing plate moving up and down, and the head of described push rod links to each other with the bottom surface of pressing plate.Move liquid though this liquid-transfering device can carry out the high flux of 96 passages simultaneously, the distance between its each liquid-transfering device can not be adjusted.In the experimentation of reality, usually transfer liquid between different multichannel load sample containers, the channel pitch difference of different multichannel load sample containers, for example the distance between distance between 96 orifice bores and the hole and the general Ago-Gel glue comb Kong Yukong is different, using the fixing multi-channeled transposition arrangement of existing channel pitch to carry out liquid shifts, operate very inconveniently, and cause operate miss easily.
The utility model content
At the problems referred to above, the purpose of this utility model is to provide a kind of multi-channeled transposition arrangement, and its channel pitch can be adjusted, and can carry out multichannel liquid flexibly and shift.
For achieving the above object, the utility model adopts following technical scheme:
The utility model provides a kind of multichannel pipettor, comprises framework 3 and liquid-transfering device 5, is provided with supporting mechanism 4 in the framework, is fixed with at least two described liquid-transfering devices 5 on the supporting mechanism, and described supporting mechanism 4 is a telescoping mechanism.
One of the utility model preferred embodiment in, described supporting mechanism 4 is a scissors mechanism 4.
One of the utility model preferred embodiment in, described scissors mechanism 4 comprises that at least one group is cut fork combination 4 by what cut that the yoke juxtaposition forms, cuts fork combination 4 one ends and fixes, the other end is connected with carriage release lever 8.
One of the utility model preferred embodiment in, described liquid-transfering device 5 is fixed on described place, crosspoint of cutting yoke.
One of the utility model preferred embodiment in, the edge of described framework is provided with chute or slide rail, the two ends of described carriage release lever are provided with corresponding slip buckle structure 16.
One of the utility model preferred embodiment in, be provided with crossbeam 6 in the described framework 3, describedly cut fork combination 4 and be slidingly connected with crossbeam 6.
One of the utility model preferred embodiment in, described each crosspoint of cutting in the fork combination 4 is and is rotationally connected, turning cylinder 10 is provided with through hole, describedly cuts the fork combination and is serially connected on the crossbeam by through hole.
One of the utility model preferred embodiment in, describedly cut fork combination 4 and be at least two groups, every group of string is at least one crossbeam 6.
One of the utility model preferred embodiment in, be provided with pressing plate 2 on the described framework, described liquid-transfering device comprises syringe needle 13, needle tubing 12 and push rod 11, and the head of described push rod is connected with the bottom surface of pressing plate 2, and described needle tubing 12 is fixedlyed connected with described supporting construction 4.
One of the utility model preferred embodiment in, described pressing plate 2 is positioned at quantitative frame 1, described quantitative frame 1 comprises a two side and an end face, its sidewall is connected with framework 3 sidewalls.
Adopt technique scheme, the beneficial effects of the utility model are: can realize that the multichannel liquid between the different load sample containers shifts.The transfer liquid volume can be measured; Distance can change between each liquid-transfering device of multichannel, can change to the purpose distance rapidly by scale; The excursion of distance is wide, from 20mm to 5mm.Each liquid-transfering device can mount and dismount easily, realizes the flexible change of port number.
Description of drawings
Fig. 1 is a multi-channeled transposition arrangement structure schematic diagram among the embodiment one;
Fig. 2 cuts poor mechanism partial cross-sectional side-elevation view among the embodiment one;
Fig. 3 is the unified schematic diagram that changes of each channel distance among the embodiment one;
Fig. 3 A is a schematic diagram of cutting liquid-transfering device pitch enlargement fixing in the poor mechanism, and Fig. 3 B cuts the schematic diagram that liquid-transfering device spacing fixing in the poor mechanism is dwindled;
Fig. 4 is the Facad structure schematic diagram of liquid-transfering device among the embodiment one;
Fig. 5 is the procedure chart of multi-channeled transposition arrangement front transfer liquid among the embodiment one; Wherein Fig. 5 A represents not regulate the schematic diagram of liquid-transfering device spacing; Fig. 5 B represents the schematic diagram of mentioning pressing plate and unclamping the slip buckle structure; Fig. 5 C represents to regulate the liquid-transfering device spacing and the fixing schematic diagram of slip buckle structure; Fig. 5 D represents to depress the schematic diagram of pressing plate.
The specific embodiment
Below in conjunction with embodiment embodiment of the present utility model is described in detail.It will be understood to those of skill in the art that the following examples only are used to illustrate the utility model, and should not be considered as limiting scope of the present utility model.
Embodiment one multi-channeled transposition arrangement moves liquid
As shown in Figure 1, multi-channeled transposition arrangement of the present utility model is cut poor mechanism 4 and liquid-transfering device 5 formations by quantitative frame 1, pressing plate 2, framework 3.
Wherein, quantitatively frame 1 is fixing by two ends screens and framework both upper ends thereof 3, can carry out assembly and disassembly flexibly with framework 3 by moving forward and backward; Quantitatively have pressing plate 2 to pass in the frame 1, can be in quantitative frame 1 vertical mobile of pressing plate 2 determined the volume of transfer liquid by the scale on the quantitative frame 1.
Pressing plate 2 moves for convenience, and described pressing plate 2 tops are provided with a handle; Described pressing plate 2 inside are hollow slots, and shape matches with the head of liquid-transfering device push rod 11, can block liquid-transfering device push rod 11, and moving up and down of control liquid-transfering device push rod 11 realizes a plurality of liquid-transfering device 5 whole unified liquid that move; Liquid-transfering device 5 in the groove can move left and right, makes things convenient for the change of distance between each liquid-transfering device 5.
Described framework 3 has six faces, and there is scale positive top and the bottom, show the distance of 5 of each liquid-transfering devices; The back side is an openable lid (referring to Fig. 1), makes things convenient for the installation and removal of liquid-transfering device 5; About face inner fixing with the crossbeam 6 of cutting poor mechanism 4; About the top of face be a screens, fixing with quantitative frame 1; Positive position up and down respectively is provided with a dead slot, cuts carriage release lever 8 side-to-side movement flexibly of poor mechanism 4 in the dead slot.
The similar widely used scalable fence structure now of described basic principle of cutting poor mechanism 4, the shape of each rhombus are the same and unified change can take place.By the carriage release lever 8 of a mobile end, the rhombus length of side is constant, and the catercorner length unification changes, and realizes the fixedly unified variation of distance (referring to Fig. 3) between the screens 9 of liquid-transfering device at place, two crosspoints about rhombus.Describedly cut poor mechanism fixedly screens 9 and cross bar screens 10 5 parts are formed (referring to Fig. 2) by two crossbeams 6, several rhombus bar 7 and carriage release lever 8, liquid-transfering device.
Described crossbeam 6 two ends are fixed in the framework, live several rhombus bars 7 by 10 strings of the cross bar screens on the rhombus bar crosspoint.
Described each rhombus of rhombus bar is made of four little bars, and the crosspoint of two little bars is provided with liquid-transfering device 5 fixedly screens 9 and cross bar screens 10.
Described cross bar screens 10 integral body be one cylindrical, forward part is passed two little bars of rhombus, there is a cuboid hollow out rear section, allows cross bar pass.Move when cutting poor mechanism 4 one ends, per two little bars of rhombus are around cross bar screens rotation, and also move left and right on cross bar of cross bar screens 10.
Described liquid-transfering device fixedly screens 9 is cylinders, can fix (as shown in Figure 4) with the spill room of liquid-transfering device 5 fronts, and liquid-transfering device fixedly screens 9 is fixed on cross bar screens 10 back.
As shown in Figure 3, described carriage release lever 8 is enclosed within on the crossbeam 6 by the cuboid 15 of two hollow outs, little bar of the rhombus of cuboid and low order end and carriage release lever 8 are fixing, when carriage release lever 8 moves horizontally, cuboid 15 moves horizontally on crossbeam 6, the little bar of rhombus by low order end drives contraction or the extension on whole rhombus bar 7 levels, and what fixedly the distance between the cross bar screens 10 of liquid-transfering device 5 was also unified thereupon changes, and has realized the change of distance between each liquid-transfering device 5; Carriage release lever has a slip buckle structure 16 (referring to Fig. 5) in two ends about in the of 8, can stretch out framework 3 fronts, fixed frame 3 header boards, and reflect distance between the liquid-transfering device 5 by the scale on the header board.
Described liquid-transfering device 5 is formed (referring to Fig. 4) by push rod 11, syringe 12, syringe needle 13, and syringe 12 antethecas are thicker, is provided with two holes 14, and fixedly screens 9 is fixing with liquid-transfering device, makes things convenient for the assembly and disassembly of liquid-transfering device 5.About face bucket wall thinner, thickness is 2.5mm, makes two minimum ranges between the syringe reach 5mm, is fit to sample on the various gels.The push rod head is made elliptical cylinder-shape, and the front and rear part is outstanding, can well be fixed on the pressing plate.
Multi-channeled transposition arrangement moves the process of liquid:
1) as Fig. 4, multi-channeled transposition arrangement is made up of several identical liquid-transfering devices 5, each liquid-transfering device 5 is made up of push rod 11, syringe 12 and syringe needle 13, move up and down by push rod 11, change gas volume in the syringe 12, by air pressure liquid is compressed into syringe 12, promote liquid is discharged by push rod 11.
2) as Fig. 2, push rod 11 heads are elliptical cylinder-shape, can inlay with pressing plate 2 interior grooves.Several liquid-transfering devices 5 are embedded on the pressing plate 2, move by the unification that moves up and down the several liquid-transfering devices 5 of control of pressing plate 2.
3) as Fig. 5, the displacement of pressing plate about in the of 2 moves the volume of liquid by the reflection of the scale on the quantitative frame 1.
The distance of each passage of multi-channeled transposition arrangement changes:
1) as Fig. 3, the unified change of the distance of passage is to cut poor mechanism 4 by two covers to realize, utilize moving of a carriage release lever 8 control mobile device 4 one ends, mobile device 4 other ends are fixed on the crossbeam 6, form the length of four little bars of mobile device 4 and fix, they form a rhombus, and the rhombus diagonal takes place by unified the variation, liquid-transfering device 5 is fixed on the diagonal two ends, realizes that the unified of distance changes between the liquid-transfering device 5.Two cover rhombus devices utilize 2 principles of determining a line better to fix each root liquid-transfering device 5.
2) carriage release lever 8 can be determined concrete distance between the liquid-transfering device 5 by the scale of framework header board, by specific scale (is distance between 96 orifice bores and the hole as 9mm), realizes changing fast the distance between the liquid-transfering device 5.
3) as Fig. 5, carriage release lever is provided with the slip buckle structure 16 (referring to Fig. 5) of fixed frame header board in two ends about in the of 8, can press the button after the distance of determining between the liquid-transfering device in case cause the change of distance because shake.
The change of multichannel port number:
1) as Fig. 2 and Fig. 4, every liquid-transfering device 5 is fixing with 9 on the liquid-transfering gun card of cutting in the poor mechanism by two holes 14 in front, and liquid-transfering gun push rod head and the embedding of pressing plate inside groove are lived.
2) by quantitative frame 1 move forward and backward, pressing plate 2 move left and right can carry out assembly and disassembly with quantitative frame 1 and pressing plate 2, open the lid on the framework backboard, just can carry out the assembly and disassembly of liquid-transfering device, realize the change of port number.

Claims (10)

1. a multi-channeled transposition arrangement comprises framework and liquid-transfering device, is provided with supporting mechanism in the framework, is fixed with at least two described liquid-transfering devices on the supporting mechanism, it is characterized in that: described supporting mechanism is a telescoping mechanism.
2. multi-channeled transposition arrangement according to claim 1 is characterized in that: described supporting mechanism is a scissors mechanism.
3. multi-channeled transposition arrangement according to claim 2 is characterized in that: described scissors mechanism comprises that at least one group is cut the fork combination by what cut that the yoke juxtaposition forms, cuts fork combination (4) one ends and fixes, and the other end is connected with carriage release lever.
4. multi-channeled transposition arrangement according to claim 3 is characterized in that: described liquid-transfering device is fixed on described place, crosspoint of cutting yoke.
5. multi-channeled transposition arrangement according to claim 3 is characterized in that: the edge of described framework is provided with chute or slide rail, and the two ends of described carriage release lever are provided with corresponding slip buckle structure.
6. multi-channeled transposition arrangement according to claim 3 is characterized in that: be provided with crossbeam in the described framework, describedly cut fork combination and be slidingly connected with crossbeam.
7. multi-channeled transposition arrangement according to claim 6 is characterized in that: described each crosspoint of cutting in the fork combination is and is rotationally connected, and turning cylinder is provided with through hole, described cut the fork combination by the through hole string on crossbeam.
8. multi-channeled transposition arrangement according to claim 7 is characterized in that: describedly cut fork combination and be at least two groups, every group of string is at least one crossbeam.
9. according to each described multi-channeled transposition arrangement of claim 1-8, it is characterized in that: be provided with pressing plate on the described framework, described liquid-transfering device comprises syringe needle, needle tubing and push rod, and the head of described push rod is connected with the bottom surface of pressing plate, and described needle tubing is fixedlyed connected with described supporting construction.
10. multi-channeled transposition arrangement according to claim 8 is characterized in that: described pressing plate is positioned at quantitative frame, and described quantitative frame comprises a two side and an end face, and its sidewall is connected with frame side wall.
CN2010205777023U 2010-10-25 2010-10-25 Multichannel pipetting device Expired - Fee Related CN201823545U (en)

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103586095A (en) * 2013-11-26 2014-02-19 东南大学 Multichannel pipettor
CN105396634A (en) * 2015-08-11 2016-03-16 广州康昕瑞基因健康科技有限公司 Pipetting needle distance adjustment apparatus
CN106347973A (en) * 2015-07-17 2017-01-25 浙江万里学院 Automatic sorter for centrifuge tubes
CN107703474A (en) * 2017-08-10 2018-02-16 嘉兴学院 A kind of electric equipment products detection means and control method
CN108220151A (en) * 2018-03-10 2018-06-29 苏州承美生物科技有限公司 A kind of spot sample device for genetic engineering
CN108251294A (en) * 2018-03-10 2018-07-06 苏州承美生物科技有限公司 A kind of genetic test drop sample equipment
CN108816303A (en) * 2018-07-19 2018-11-16 无锡百泰克生物技术有限公司 Multichannel spacing is adjustable liquid-transfering gun
CN109760197A (en) * 2019-04-15 2019-05-17 湖南三一快而居住宅工业有限公司 Stop gauge and material distributing machine for steel bar girder precast concrete
CN112206843A (en) * 2019-07-12 2021-01-12 华大青兰生物科技(无锡)有限公司 Device for transferring liquid
CN113171808A (en) * 2021-03-30 2021-07-27 广东乾晖生物科技有限公司 Connecting rod type interval adjusting device and liquid shifter
CN113198555A (en) * 2021-03-30 2021-08-03 广东乾晖生物科技有限公司 Button type interval adjusting device and liquid transferring device

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103586095A (en) * 2013-11-26 2014-02-19 东南大学 Multichannel pipettor
CN106347973A (en) * 2015-07-17 2017-01-25 浙江万里学院 Automatic sorter for centrifuge tubes
CN105396634A (en) * 2015-08-11 2016-03-16 广州康昕瑞基因健康科技有限公司 Pipetting needle distance adjustment apparatus
CN107703474B (en) * 2017-08-10 2020-02-04 嘉兴学院 Electric appliance product detection device and control method
CN107703474A (en) * 2017-08-10 2018-02-16 嘉兴学院 A kind of electric equipment products detection means and control method
CN108220151A (en) * 2018-03-10 2018-06-29 苏州承美生物科技有限公司 A kind of spot sample device for genetic engineering
CN108251294A (en) * 2018-03-10 2018-07-06 苏州承美生物科技有限公司 A kind of genetic test drop sample equipment
CN108816303A (en) * 2018-07-19 2018-11-16 无锡百泰克生物技术有限公司 Multichannel spacing is adjustable liquid-transfering gun
CN109760197A (en) * 2019-04-15 2019-05-17 湖南三一快而居住宅工业有限公司 Stop gauge and material distributing machine for steel bar girder precast concrete
CN109760197B (en) * 2019-04-15 2019-07-05 湖南三一快而居住宅工业有限公司 Stop gauge and material distributing machine for steel bar girder precast concrete
CN112206843A (en) * 2019-07-12 2021-01-12 华大青兰生物科技(无锡)有限公司 Device for transferring liquid
CN113171808A (en) * 2021-03-30 2021-07-27 广东乾晖生物科技有限公司 Connecting rod type interval adjusting device and liquid shifter
CN113198555A (en) * 2021-03-30 2021-08-03 广东乾晖生物科技有限公司 Button type interval adjusting device and liquid transferring device
CN113198555B (en) * 2021-03-30 2022-01-18 广东乾晖生物科技有限公司 Button type interval adjusting device and liquid transferring device
CN113171808B (en) * 2021-03-30 2022-03-15 广东乾晖生物科技有限公司 Connecting rod type interval adjusting device and liquid shifter

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GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110511

Termination date: 20151025

EXPY Termination of patent right or utility model