CN201609654U - Large flow circulation pool for industrial preparative chromatography - Google Patents
Large flow circulation pool for industrial preparative chromatography Download PDFInfo
- Publication number
- CN201609654U CN201609654U CN2009201757460U CN200920175746U CN201609654U CN 201609654 U CN201609654 U CN 201609654U CN 2009201757460 U CN2009201757460 U CN 2009201757460U CN 200920175746 U CN200920175746 U CN 200920175746U CN 201609654 U CN201609654 U CN 201609654U
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- Prior art keywords
- cavity
- light beam
- plug
- flow cell
- inner chamber
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- Expired - Lifetime
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- 238000004237 preparative chromatography Methods 0.000 title abstract description 6
- 239000012530 fluid Substances 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims description 13
- 239000013307 optical fiber Substances 0.000 claims description 5
- 210000004907 gland Anatomy 0.000 claims description 4
- 238000001514 detection method Methods 0.000 abstract description 7
- 239000007788 liquid Substances 0.000 abstract description 3
- 238000004847 absorption spectroscopy Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 4
- 238000000862 absorption spectrum Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
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Abstract
The utility model relates to a large flow circulation pool for industrial preparative chromatography, which comprises a cavity body for leading fluid to pass through, and is characterized in that cavity body plugs which are convex towards the inside of the cavity body are symmetrically arranged on the wall of the cavity body, a detecting region is formed between the two cavity body plugs, and light pillars which are arranged oppositely are arranged at the middle parts of the two cavity body plugs. The large flow circulation pool for the industrial preparative chromatography has reasonable structural design and can be matched with an ultraviolet-visible absorption spectroscopy detector within the flow range of 20-80L/min, and realize the accurate detection of fractions after a separation column. A shunt device is unnecessary to be additionally arranged, the flow rate of gas and liquid of the detecting part is smooth, and components in the circulation pool can be accurately analyzed according to the absorbency, thereby providing reliable data basis for the next step of collecting the fractions.
Description
Technical field
The utility model belongs to preparing chromatograph in industry Device Testing components and parts, is specifically related to a kind of preparing chromatograph in industry with big flow flow cell.
Background technology
The main purpose of preparing chromatograph in industry is to obtain pure material from mixture.The efficient of separating with raising for the time of accelerating to separate, the preparative chromatography device to advance sample size very big, cause the corresponding increasing of the segregational load of preparative chromatography post, also just must strengthen chromatographic column filler, increase the diameter and the length of preparative chromatography, many relatively mobile phases of use.For big flow flow cell is cut behind the splitter of flowing through in the analysis cell when carrying out check and analysis, and general allowable maximum velocity only is 5mL/min or 10mL/min, and excessive flow velocity can influence the detection effect of spectral detection instrument.The flow cell that available technology adopting is special, its allowable maximum velocity can be 150mL/min.This flow cell adopts the bypass separator tube, the small volume of fluid shunting is imported detect, though this is a good way, the error of its testing result can be relatively large.
The utility model content
The utility model provides a kind of reasonable in design, can be in the range of flow of 20-80L/min, cooperate the uv-visible absorption spectra detector, and the preparing chromatograph in industry of accurate detection of realizing the cut behind the splitter is with big flow flow cell.It need not to add part flow arrangement, and the gas-liquid flow velocity that detects the position is steady, can analyze wherein composition accurately according to its absorptance, for next step fraction collection provides reliable data foundation.
The technical scheme that the utility model adopted is as follows:
A kind of preparing chromatograph in industry is with big flow flow cell, comprise the cavity that a fluid passes through, it is characterized in that being symmetrical arranged on the described cavity wall to the projecting inward cavity plug of cavity, form surveyed area between two cavity plugs, the middle part of described two cavity plugs is provided with the light beam that is oppositely arranged.
Concretely, described cavity is a cylindrical cavity, and the radial direction of its cavity wall is symmetrical arranged two cavity plugs, and this cavity plug is oval column.
The diameter of described cavity plug is greater than the radius of described cavity, and the top of described cavity plug has slick and sly edge.
Described light beam connects optical fiber respectively by fibre-optical splice.
Described light beam is positioned at the top middle portion of cavity plug, and the cavity plug has an inner chamber, and a light beam sealing shroud is set in this inner chamber, and the described light beam of light beam sealing shroud suit forms the sealing that this inner chamber and described cavity are asked.
Set gradually light beam gland and catch outside the described light beam sealing shroud and between fibre-optical splice.
Described light beam joint outer setting one fastening bolt is threaded between the inner chamber of this fastening bolt and described cavity plug fibre-optical splice is fixed in the inner chamber of cavity plug.
This preparing chromatograph in industry with big flow flow cell by in the inner chamber of existing flow cell, two symmetrically arranged cavity plugs being set, these two cavity plugs are provided with in a diameter direction of inner chamber, form surveyed area between the top of two cavity plugs, detected fluid is by flow cell the time, the cavity plug that runs into protrusion can produce shunting, the detection position of detected fluid between this cavity plug forms flow velocity fluid stream comparatively stably, light beam can detect the absorptance of this fluid by the optical fiber of its connection, analyze composition wherein, for next step fraction collection provides the accurate data foundation.Shaven head can be installed on the center, top of cavity plug by the mode that inner chamber is set in the cavity plug, by corresponding light beam sealing shroud, light beam gland and catch, can realize the installation that it is firm.The fibre-optical splice that connects optical fiber also can be realized being connected with the good of spectral detection instrument by in the firm inner chamber that is fixed in this cavity plug of fastening bolt.
The beneficial effects of the utility model are that this preparing chromatograph in industry can cooperate the uv-visible absorption spectra detector, the accurate detection of the cut behind the realization splitter with the reasonable in design of big flow flow cell in the range of flow of 20-80L/min.It need not to add part flow arrangement, and the gas-liquid flow velocity that detects the position is steady, can analyze wherein composition accurately according to its absorptance, for next step fraction collection provides reliable data foundation.
Below in conjunction with accompanying drawing and concrete real-time mode the utility model is further elaborated.
Description of drawings
Fig. 1 is the structural representation of the utility model specific embodiment;
Fig. 2 is that the A-A of Fig. 1 is to cross-sectional view;
Fig. 3 is that the B-B of Fig. 2 is to cross-sectional view.
The specific embodiment
As Fig. 1, Fig. 2 and shown in Figure 3, this preparing chromatograph in industry has the cavity 10 that a fluid passes through with big flow flow cell, this cavity 10 is a cylindrical cavity, be symmetrical arranged on the cavity wall to the projecting inward cavity plug 30 of cavity, two cavity plugs are symmetrical arranged along the radial direction of its cavity wall, this cavity plug is oval column, and the long axis direction of oval column is consistent with the fluid flow direction in the cavity.The major diameter of cavity plug is greater than the radius of cavity, and the top of cavity plug has slick and sly edge.Form narrow surveyed area between two cavity plugs, two light beams 21 lay respectively at the top middle portion of cavity plug, two light beams all connect optical fiber 20 respectively by fibre-optical splice 25, the cavity plug has an inner chamber, one light beam sealing shroud 22 is set in this inner chamber, and light beam sealing shroud suit light beam forms the sealing between this inner chamber and cavity.Set gradually light beam gland 23 and catch 24 outside the light beam sealing shroud and between fibre-optical splice.Light beam joint 25 outer setting one fastening bolt 26 is threaded between the inner chamber of this fastening bolt 26 and cavity plug 30 fibre-optical splice 25 is fixed in the inner chamber of cavity plug.
Claims (7)
1. a preparing chromatograph in industry is with big flow flow cell, comprise the cavity that a fluid passes through, it is characterized in that being symmetrical arranged on the described cavity wall to the projecting inward cavity plug of cavity, form surveyed area between two cavity plugs, the middle part of described two cavity plugs is provided with the light beam that is oppositely arranged.
2. preparing chromatograph in industry according to claim 1 is characterized in that with big flow flow cell described cavity is a cylindrical cavity, and the radial direction of its cavity wall is symmetrical arranged two cavity plugs, and this cavity plug is oval column.
3. preparing chromatograph in industry according to claim 2 is characterized in that the radius of the diameter of described cavity plug greater than described cavity with big flow flow cell, and the top of described cavity plug has slick and sly edge.
4. preparing chromatograph in industry according to claim 1 is characterized in that with big flow flow cell described light beam connects optical fiber respectively by fibre-optical splice.
5. preparing chromatograph in industry according to claim 1 is with big flow flow cell, it is characterized in that described light beam is positioned at the top middle portion of cavity plug, the cavity plug has an inner chamber, one light beam sealing shroud is set in this inner chamber, and the described light beam of light beam sealing shroud suit forms the sealing between this inner chamber and described cavity.
6. preparing chromatograph in industry according to claim 5 is characterized in that setting gradually light beam gland and catch outside the described light beam sealing shroud and between fibre-optical splice with big flow flow cell.
7. preparing chromatograph in industry according to claim 5 is characterized in that light beam joint outer setting one fastening bolt with big flow flow cell, is threaded between the inner chamber of this fastening bolt and described cavity plug fibre-optical splice is fixed in the inner chamber of cavity plug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009201757460U CN201609654U (en) | 2009-09-01 | 2009-09-01 | Large flow circulation pool for industrial preparative chromatography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009201757460U CN201609654U (en) | 2009-09-01 | 2009-09-01 | Large flow circulation pool for industrial preparative chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201609654U true CN201609654U (en) | 2010-10-20 |
Family
ID=42960285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009201757460U Expired - Lifetime CN201609654U (en) | 2009-09-01 | 2009-09-01 | Large flow circulation pool for industrial preparative chromatography |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201609654U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102128789A (en) * | 2010-11-24 | 2011-07-20 | 利穗科技(苏州)有限公司 | Flowing cell with high flow |
| CN107252304A (en) * | 2013-01-09 | 2017-10-17 | 富士胶片株式会社 | Photoacoustic image generating device and insert |
| CN107615058A (en) * | 2015-06-01 | 2018-01-19 | 株式会社岛津制作所 | Preparative Chromatography |
| CN110346461A (en) * | 2018-04-03 | 2019-10-18 | 中国科学院大连化学物理研究所 | A kind of light detection flow cell |
-
2009
- 2009-09-01 CN CN2009201757460U patent/CN201609654U/en not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102128789A (en) * | 2010-11-24 | 2011-07-20 | 利穗科技(苏州)有限公司 | Flowing cell with high flow |
| CN107252304A (en) * | 2013-01-09 | 2017-10-17 | 富士胶片株式会社 | Photoacoustic image generating device and insert |
| CN107615058A (en) * | 2015-06-01 | 2018-01-19 | 株式会社岛津制作所 | Preparative Chromatography |
| CN107615058B (en) * | 2015-06-01 | 2020-01-17 | 株式会社岛津制作所 | Preparative Chromatograph |
| CN110346461A (en) * | 2018-04-03 | 2019-10-18 | 中国科学院大连化学物理研究所 | A kind of light detection flow cell |
| CN110346461B (en) * | 2018-04-03 | 2022-01-11 | 中国科学院大连化学物理研究所 | Light detection flow cell |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20101020 |
|
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Beijing Chuangxin Tongheng Science and Technology Co., Ltd. Document name: Notification of Expiration of Patent Right Duration |