CN201390395Y - Freon-free medical aerosol one-step-method production device - Google Patents
Freon-free medical aerosol one-step-method production device Download PDFInfo
- Publication number
- CN201390395Y CN201390395Y CN200920021100U CN200920021100U CN201390395Y CN 201390395 Y CN201390395 Y CN 201390395Y CN 200920021100 U CN200920021100 U CN 200920021100U CN 200920021100 U CN200920021100 U CN 200920021100U CN 201390395 Y CN201390395 Y CN 201390395Y
- Authority
- CN
- China
- Prior art keywords
- cylinder
- valve
- piston rod
- inlet opening
- metering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Landscapes
- Vacuum Packaging (AREA)
Abstract
The utility model relates to a pharmacy device, and in particular to an one-step-method production device for producing Freon-free medical aerosol (HFA), which comprises a high-pressure proportioning tank (1), a pneumatic hydraulic membrane pump (2), a disconnecting valve A (3), a meter (4), a quantitative filling device (5) and a disconnecting valve B (6) which are sequentially communicated with each other to form a cycle, wherein a retaining valve (7) is respectively arranged between the high-pressure proportioning tank (1) and the pneumatic hydraulic membrane pump (2) and between the pneumatic hydraulic membrane pump (2) and the disconnecting valve A (3), the quantitative filling device (5) is connected with a vacuumed medicine container, and the quantitative filing device (5) performs the quantitative filling for the medicine container. The production device can work continuously for 24 hours and has precise filling measurement and small volatilization of propellant; moreover, the suspension liquid in the entire system stays at the liquefied state, and after the suspension liquid is quantitatively filled, the active ingredients in each filling unit can be ensured to be homogenous, so that the production device creates conditions for producing the Freon-free medical aerosol in China.
Description
Technical field
The utility model is a kind of drugs manufacture equipment, specifically a kind of production no dichlorodifluromethane medicinal aerosol (HFA) single stage method process units that is used for.
Technical background:
Medicinal aerosol has been a common formulations abroad, is characterized in rapid-action, secondary action is little, does not need through GI absorption the utilization ratio of drug height.Medicinal aerosol can be divided into two kinds of three-phase suspension type (gas phase, liquid phase, solid phase) and two-phase solution-types (gas phase, liquid phase), and wherein three-phase suspension type engineering factor requires high.China's two-phase solution-type medicinal aerosol that begins one's study from the sixties, but make slow progress, it is also very slow to produce the corresponding Equipment Development of medicinal aerosol.The country that can produce the medicinal aerosol equipment of three-phase supensoid agent at present in the world also has only a few company of a few countries such as Switzerland, Italy.
According to 1986 " Montreal Agreement ", various countries finished substituting of dichlorodifluromethane propellant before 2010.At present external pharmacy major company has finished the non-preferably chlorofluoromethane refrigerant hydro carbons of safety propellant (HFA134a and HFA227) substantially and has substituted, and carries out Research on Process.External HFA production facilities is to concentrate on a station with vacuumizing and seal valve, and parts and complexity thereof are unfavorable for maintaining and hygiene.
Summary of the invention:
No dichlorodifluromethane medicinal aerosol (HFA) three phase aerosol production characteristics are: HFA134a also plays the effect of dispersing agent simultaneously as propellant, in the high pressure preparing tank, form steady suspension at drug prescription mesohigh adding 134a (being liquid phase under the high pressure) and inhibiter, active constituents of medicine (solid phase), with this suspending fluid quantitative filling in the medicine container that vacuumizes, for control asthma, COPD, cardiovascular disease tired, that endocrine is tired is used.
The purpose of this utility model is at above-mentioned production characteristics, and a kind of single stage method process units that is used for producing no dichlorodifluromethane medicinal aerosol (HFA) is provided.Design-calculated of the present invention equipment clearly is divided into process units five modules fully in conjunction with HFA one-step method production process characteristics, be respectively automatic sorting module, the proportional valve of medicine container automatic arrangement drop valve module, vacuumize module, quantitative filling module.The PLC that can realize of each unit controls, and realizes the online detection of product parameters, and prints detection record, can play the traceability of product design.Equipment carries FFU and reaches aseptic technique fully.The parts that contact with medicine adopt 316 corrosion-resistant steels, and online design CIP washing equipment.
For achieving the above object, the technical scheme that the utility model is taked is: include high pressure preparing tank, Pneumatic hydraulic membrane pump, shutoff valve A, metering device, quantitative filling device, shutoff valve B etc.High pressure preparing tank, Pneumatic hydraulic membrane pump, shutoff valve A, metering device, quantitative filling device, shutoff valve B, high pressure preparing tank are communicated with successively and form circulation, between high pressure preparing tank and the Pneumatic hydraulic membrane pump, be provided with check valve between Pneumatic hydraulic membrane pump and the shutoff valve A, quantitative filling device is connected with the medicine container that vacuumizes, and by quantitative filling device medicine container is carried out quantitative filling.
During use; in the high pressure preparing tank, add HFA134a and required medicine by a certain percentage; the sealing pressurization; under the protection of circulation thermal insulation medium (generally can adopt water); holding temperature is 10～15 ℃ in jar; pressure is 0.5～0.6Mpa, and homogeneous is 24 hours continuously, and the volatile quantity of HFA134a is controlled at below 1%.Under this situation, HFA134a is in liquefaction, and by means of the effect of inhibiter, active constituents of medicine is in the suspended state of homogeneous all the time in total system.Deflocculant is under the effect of Pneumatic hydraulic membrane pump, by high pressure preparing tank → Pneumatic hydraulic membrane pump → shutoff valve A → metering device → quantitative filling device → shutoff valve B → high pressure preparing tank, form circulation, and realize the medicine container that vacuumizes is carried out quantitative filling at quantitative filling device.
The version of Pneumatic hydraulic membrane pump is a lot, can include upper shell, lower house, elastic memberance, cylinder I, seal ring etc.Lower house is provided with inlet opening and fluid hole.Lower house is fixed on the upper shell and is provided with elastic memberance between upper and lower casing, between elastic memberance and lower house, be provided with the suspension sap cavity, between elastic memberance and upper shell, be provided with fluid chamber, upper shell is fixed on the cylinder and is provided with seal ring, and the piston rod of cylinder I puts in the fluid chamber of upper shell.When the piston rod of cylinder I moves back and forth in fluid chamber, by hydraulic oil drive the elastic memberance motion with suspending fluid from the inlet opening pump of the lower house sap cavity that advances to suspend, pump from fluid hole again, play the effect of " pump ".In order to improve antiseptic power, elastic memberance adopts polytetrafluoroethylmaterial material.
The version of shutoff valve A, shutoff valve B is a lot, and shutoff valve A can adopt identical version with the version of shutoff valve B: include cylinder I I, valve body, sealing mold insert, sealing member etc.The end of the piston rod of cylinder I I is fixed with the sealing mold insert, and valve body is provided with inlet opening, fluid hole.Cylinder I I is fixed on the valve body, and the piston rod of cylinder I I puts in the valve body and by sealing the inlet opening that empiecement withstands (promptly closing) valve body, is provided with sealing member between cylinder I I and valve body.In order to improve antiseptic power, the material of sealing mold insert all adopts polytetrafluoroethylmaterial material.When the piston rod of cylinder I I stretched out the inlet opening that withstands valve body, gas control barrier film shutoff valve was in closed condition.When piston rod shrank, inlet opening was opened, and shutoff valve is in opening, and suspending fluid enters shutoff valve by inlet opening, was flowed out by fluid hole again.
The version of metering device is also a lot, can include metering regulating control that measures body, cylinder I II and the scalable cylinder piston throw of lever etc.The inlet opening, the fluid hole that are provided with the suspension sap cavity and are communicated with in the metering body with the suspension sap cavity.The end of cylinder I II is captiveed joint with the metering body and seal ring is housed, the piston rod of cylinder I II put in the metering body the suspension sap cavity, and can withstand (promptly closing) inlet opening, the other end of cylinder I II is equipped with the metering regulating control of the scalable cylinder piston throw of lever.Realize canned metering by the stroke of adjusting piston bar.During use, adjust the stroke of piston rod by measuring regulating control, promptly adjust canned amount, manipulating cylinder III shrinks piston rod, breaks away from inlet opening, promptly opens inlet opening, and suspending fluid is entered the inner chamber of metering body by inlet opening; Manipulating cylinder III stretches out piston rod, withstands the inlet opening of metering body, simultaneously the suspending fluid of metering device intracoelomic cavity is discharged by fluid hole.
The version of quantitative filling device is also a lot, can include can body, cylinder I V etc., and the piston rod top of cylinder I V is provided with push rod, and the can body is provided with inlet opening, fluid hole, can hole.Cylinder I V is fixed on the can body and is provided with seal ring, and the piston rod of cylinder I V puts in the can body, and the push rod on piston rod top injects in the can hole.When the needs can, the valve rod of the proportional valve on the medicine container that vacuumizes is inserted in the canned hole of can body, manipulating cylinder IV, piston rod stretches out, the push rod on piston rod top promotes the valve rod of proportional valve, opens proportional valve, and piston rod stops up the fluid hole of can body simultaneously, suspending fluid by inlet opening through filling machine intracoelomic cavity, can hole, proportional valve, can in the medicine container that vacuumizes.After can finished, manipulating cylinder IV resetted piston rod, and the fluid hole of can body is opened thereupon, and the valve rod of proportional valve also resets thereupon, closes proportional valve, and suspending fluid is flowed out by liquid outlet.
Because the utility model has designed circulating device by high pressure preparing tank → Pneumatic hydraulic membrane pump → gas control barrier film shutoff valve A → metering device → quantitative filling device → gas control barrier film shutoff valve B → high pressure preparing tank, and realize the medicine container that vacuumizes is carried out quantitative filling at quantitative filling device.Can realize work in continuous 24 hours, filling measurement is accurate, and the propellant volatile quantity is little, suspending fluid is in liquefaction in the total system, after suspending fluid carries out quantitative filling, can guarantee each filling element Chinese traditional medicine active ingredient homogeneous, create condition for China produces no dichlorodifluromethane medicinal aerosol.
Description of drawings:
Fig. 1 is the utility model scheme drawing;
Fig. 2 is a Pneumatic hydraulic membrane pump scheme drawing;
Fig. 3 pharmaceutical grade health shutoff valve scheme drawing;
Fig. 4 is the metering device scheme drawing;
Fig. 5 is the quantitative filling device scheme drawing.
The specific embodiment:
Accompanying drawing is an embodiment of the present utility model, includes high pressure preparing tank 1, Pneumatic hydraulic membrane pump 2, shutoff valve A3, metering device 4, quantitative filling device 5, shutoff valve B6 etc.High pressure preparing tank 1, Pneumatic hydraulic membrane pump 2, shutoff valve A3, metering device 4, quantitative filling device 5, shutoff valve B6, high pressure preparing tank 1 are communicated with successively and form circulation, between high pressure preparing tank 1 and the Pneumatic hydraulic membrane pump 2, be provided with check valve 7 between Pneumatic hydraulic membrane pump 2 and the shutoff valve A3, quantitative filling device 5 is connected with the medicine container that vacuumizes, and carries out quantitative filling by 5 pairs of medicine containers of quantitative filling device.
During use; in high pressure preparing tank 1, add HFA134a and required medicine by a certain percentage; sealing is heated; under the protection of circulation thermal insulation medium (as water); holding temperature is 10～15 ℃ in jar; pressure is 0.5～0.6Mpa, and homogeneous is 24 hours continuously, and the volatile quantity of HFA134a is controlled at below 1%.Under this situation, HFA134a is in liquefaction, and by means of the effect of inhibiter, active constituents of medicine is in the suspended state of homogeneous all the time in total system.Deflocculant is under the effect of Pneumatic hydraulic membrane pump (), by high pressure preparing tank 1 → Pneumatic hydraulic membrane pump 2 → shutoff valve A3 → metering device 4 → quantitative filling device 5 → shutoff valve B6 → high pressure preparing tank 1, form circulation, and realize the medicine container that vacuumizes is carried out quantitative filling at quantitative filling device 5.
The version of Pneumatic hydraulic membrane pump 2 is a lot, and present embodiment includes upper shell 21, lower house 22, elastic memberance 23, cylinder I 24, seal ring 25 etc.Lower house 22 is provided with inlet opening and fluid hole.Lower house 22 is fixed on the upper shell 21 and between upper and lower casing 22,21 and is provided with elastic memberance 23, between elastic memberance 23 and lower house 22, be provided with the suspension sap cavity, between elastic memberance 23 and upper shell 21, be provided with fluid chamber, upper shell 21 is fixed on the cylinder 24 and is provided with seal ring 25, and the piston rod of cylinder I 24 puts in the fluid chamber of upper shell 21.When the piston rod of cylinder I 24 moves back and forth in fluid chamber, by hydraulic oil drive elastic memberance 23 motions with suspending fluid from the inlet opening pump of lower house 22 sap cavity that advances to suspend, pump from fluid hole again, play the effect of " pump ".In order to improve antiseptic power, elastic memberance 23 adopts polytetrafluoroethylmaterial material.
The version of shutoff valve A3, shutoff valve B6 is a lot, and shutoff valve A3 can adopt identical version with the version of shutoff valve B6.The shutoff valve A3 of present embodiment, shutoff valve B6 adopt identical structure, include cylinder I I 31, valve body 32, sealing mold insert 33, sealing member 34 etc.The end of the piston rod of cylinder I I 31 is fixed with sealing mold insert 33; Valve body 32 is provided with inlet opening, fluid hole.Cylinder I I 31 is fixed on the valve body 32, and the piston rod of cylinder I I 31 puts in the valve body 32 and by sealing the inlet opening that empiecement 33 withstands (promptly closing) valve body 32, is provided with sealing member 34 between cylinder I I 31 and valve body 32.In order to improve antiseptic power, the material of sealing member 34 all adopts polytetrafluoroethylmaterial material.When the piston rod of cylinder I I 31 stretched out the inlet opening that withstands valve body 32, shutoff valve was in closed condition.When piston rod shrank, inlet opening was opened, and shutoff valve is in opening, and suspending fluid enters shutoff valve by inlet opening, was flowed out by fluid hole again.
The version of metering device 4 is also a lot, and present embodiment includes metering regulating control 43 that measures body 41, cylinder I II 42 and the scalable cylinder piston throw of lever etc.The inlet opening, the fluid hole that are provided with the suspension sap cavity and are communicated with in the metering body 41 with the suspension sap cavity.The end of cylinder I II 42 is captiveed joint with metering body 41 and seal ring is housed, the piston rod of cylinder I II 42 put in metering body 41 the suspension sap cavity, and can withstand (promptly closing) inlet opening, the other end of cylinder I II 42 is equipped with the metering regulating control 43 of the scalable cylinder piston throw of lever.Realize the metering of can by the stroke of adjusting piston bar.During use, adjust the stroke of piston rod by measuring regulating control 43, promptly adjust the can amount, manipulating cylinder III 42 shrinks piston rod, breaks away from inlet opening, promptly opens inlet opening, and suspending fluid is entered the inner chamber of metering body 41 by inlet opening; Manipulating cylinder III42 stretches out piston rod, withstands the inlet opening of metering body 41, will measure the suspending fluid of body 41 inner chambers simultaneously and be discharged by fluid hole.
The version of quantitative filling device (5) is also a lot, can include can body 51, cylinder I V 52 etc., and the piston rod top of cylinder I V 52 is provided with push rod 53, and can body 51 is provided with inlet opening, fluid hole, can hole.Cylinder I V 52 is fixed on the can body 51 and is provided with seal ring 54, and the piston rod of cylinder I V 52 puts in the can body 51, and the push rod 53 on piston rod top injects in the can hole.When the needs can, the valve rod of the proportional valve on the medicine container that vacuumizes is inserted in the can hole of can body 51, manipulating cylinder IV 52, piston rod stretches out, the push rod 53 on piston rod top promotes the valve rod of proportional valve, opens proportional valve, and piston rod stops up the fluid hole (promptly closing liquid outlet) of can body 51 simultaneously, suspending fluid by inlet opening through canned body 51 inner chambers, canned hole, proportional valve, can in the medicine container that vacuumizes.After can finished, manipulating cylinder IV 52 resetted piston rod, and the fluid hole of can body 51 is opened thereupon, and the valve rod of proportional valve also resets thereupon, closes proportional valve, and suspending fluid is flowed out by liquid outlet.
Therefore, because the utility model has designed circulating device by high pressure preparing tank 1 → Pneumatic hydraulic membrane pump 2 → shutoff valve A3 → metering device 4 → quantitative filling device 5 → shutoff valve B6 → high pressure preparing tank 1, and realize the medicine container that vacuumizes is carried out quantitative filling at quantitative filling device 5.Therefore the utlity model has and to realize work in continuous 24 hours, filling measurement is accurate, the propellant volatile quantity is little, suspending fluid is in liquefaction in the total system, after suspending fluid carries out quantitative filling, can guarantee each filling element Chinese traditional medicine active ingredient homogeneous, create condition for China produces no dichlorodifluromethane medicinal aerosol.
Claims (5)
1, a kind of no dichlorodifluromethane medicinal aerosol single stage method process units, it is characterized in that: include high pressure preparing tank (1), Pneumatic hydraulic membrane pump (2), shutoff valve A (3), metering device (4), quantitative filling device (5), shutoff valve B (6), high pressure preparing tank (1), Pneumatic hydraulic membrane pump (2), shutoff valve A (3), metering device (4), quantitative filling device (5), shutoff valve B (6), high pressure preparing tank (1) is communicated with successively and forms circulation, between high pressure preparing tank (1) and Pneumatic hydraulic membrane pump (2), be provided with check valve (7) between Pneumatic hydraulic membrane pump (2) and the shutoff valve A (3), quantitative filling device (5) is connected with the medicine container that vacuumizes.
2, no dichlorodifluromethane medicinal aerosol single stage method process units according to claim 1, it is characterized in that: described Pneumatic hydraulic membrane pump (2) includes upper shell (21), lower house (22), elastic memberance (23), cylinder I (24), seal ring (25); Lower house (22) is provided with inlet opening and fluid hole; Lower house (22) is fixed on upper shell (21) and goes up and be provided with elastic memberance (23) between upper and lower casing (21), (22), between elastic memberance (23) and lower house (21), be provided with the suspension sap cavity, between elastic memberance (23) and upper shell (22), be provided with fluid chamber, upper shell (22) is fixed on the cylinder (24) and is provided with seal ring (25), and the piston rod of cylinder I (24) puts in the fluid chamber of upper shell (22).
3, no dichlorodifluromethane medicinal aerosol single stage method process units according to claim 1 is characterized in that: described shutoff valve A (3), shutoff valve B (6) all include cylinder I I (31), valve body (32), sealing empiecement (33), sealing member (34); The end of the piston rod of cylinder I I (31) is fixed with sealing empiecement (33); Valve body (32) is provided with inlet opening, fluid hole; Cylinder I I (31) is fixed on the valve body (32), and the piston rod of cylinder I I (31) puts in the valve body (32), also withstands the inlet opening of valve body (32) by sealing empiecement (33), is provided with sealing member between cylinder I I (31) and valve body (32).
4, no dichlorodifluromethane medicinal aerosol single stage method process units according to claim 1, it is characterized in that: described metering device (4) includes the metering regulating control (43) that measures body (41), cylinder I II (42) and the scalable cylinder piston throw of lever; The inlet opening, the fluid hole that are provided with the suspension sap cavity in the metering body (41) and are communicated with the suspension sap cavity; The end of cylinder I II (42) is captiveed joint with metering body (41) and seal ring is housed, the piston rod of cylinder I II (42) put in metering body (41) the suspension sap cavity, and can withstand inlet opening, the other end of cylinder I II (42) is equipped with the metering regulating control (43) of the scalable cylinder piston throw of lever.
5, no dichlorodifluromethane medicinal aerosol single stage method process units according to claim 1, it is characterized in that: described quantitative filling device (5) includes can body (51), cylinder I V (52); The piston rod top of cylinder I V (52) is provided with push rod (53), and can body (51) is provided with inlet opening, fluid hole, can hole; Cylinder I V (52) is fixed on the can body (51) and is provided with seal ring (54), and the piston rod of cylinder I V (52) puts in the can body (51), and the push rod on piston rod top (53) injects in the can hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200920021100U CN201390395Y (en) | 2009-04-20 | 2009-04-20 | Freon-free medical aerosol one-step-method production device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200920021100U CN201390395Y (en) | 2009-04-20 | 2009-04-20 | Freon-free medical aerosol one-step-method production device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201390395Y true CN201390395Y (en) | 2010-01-27 |
Family
ID=41597217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200920021100U Expired - Lifetime CN201390395Y (en) | 2009-04-20 | 2009-04-20 | Freon-free medical aerosol one-step-method production device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201390395Y (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108583951A (en) * | 2018-04-11 | 2018-09-28 | 芜湖力博机械科技有限公司 | A kind of novel plunger-type diaphragm pump bulking system |
| CN111606280A (en) * | 2019-07-29 | 2020-09-01 | 昆山鑫方盛工业自动化设备有限公司 | Freon filling production line and production method thereof |
| CN115027732A (en) * | 2022-07-28 | 2022-09-09 | 扬州美达灌装机械有限公司 | High-efficient duplex position aerosol liquid filling machine |
-
2009
- 2009-04-20 CN CN200920021100U patent/CN201390395Y/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108583951A (en) * | 2018-04-11 | 2018-09-28 | 芜湖力博机械科技有限公司 | A kind of novel plunger-type diaphragm pump bulking system |
| CN111606280A (en) * | 2019-07-29 | 2020-09-01 | 昆山鑫方盛工业自动化设备有限公司 | Freon filling production line and production method thereof |
| CN111606280B (en) * | 2019-07-29 | 2024-02-20 | 昆山鑫方盛工业自动化设备有限公司 | Freon filling production line and production method thereof |
| CN115027732A (en) * | 2022-07-28 | 2022-09-09 | 扬州美达灌装机械有限公司 | High-efficient duplex position aerosol liquid filling machine |
| CN115027732B (en) * | 2022-07-28 | 2023-09-22 | 扬州美达灌装机械有限公司 | High-efficient duplex position aerosol liquid filling machine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN201705319U (en) | Skid-mounted closed dosing device | |
| CN201390395Y (en) | Freon-free medical aerosol one-step-method production device | |
| CN205914110U (en) | Novel high -efficient fluid reservoir that mixes | |
| CN105043886B (en) | A kind of natural gas pressure vessel carries out double dielectric testing devices of gas and water pressure experiment | |
| CN102888281A (en) | Method for extracting ginseng volatile oil by supercritical CO2 | |
| CN105758672A (en) | Preparing and collecting device and preparing and collecting method for oil sample of analogue transformer | |
| CN205575579U (en) | A high accuracy filling system for blowing embedment all -in -one | |
| CN209145649U (en) | A kind of refrigerating medium circulator for natural gas screw expansion electricity generation system | |
| CN109250670A (en) | A kind of automatic liquid package machine of controlled amounts | |
| CN102294061A (en) | Pressure-supplementing pressurized normal saline infusion set and manufacturing method thereof | |
| CN205367691U (en) | Filling device of oral liquid | |
| CN208268771U (en) | A kind of Dewar tank fills and device for recovering tail gas | |
| CN202397830U (en) | Stereometric formula liquid capsule filling device | |
| CN104887512A (en) | Pouring filling machine | |
| CN104887516A (en) | Liquid injection and paste injection mixed filling machine | |
| CN204684202U (en) | A kind of fluid injection note cream mixing filling machine | |
| CN1748668A (en) | Small quick multifunctional Chinese medicine preparation making machine | |
| CN205609057U (en) | Real device of instructing of operation transformer oil sampling | |
| CN102295256A (en) | Liquid chemical agent filling machine | |
| CN220843210U (en) | Petroleum fracturing propping agent bagging equipment | |
| CN205916361U (en) | Soft -packing cooking oil filling machine | |
| CN206841781U (en) | A kind of big transfusion sealer equipment of plastic bottle | |
| CN215886338U (en) | Oral liquid production filling device | |
| CN207005702U (en) | A kind of fast gas mixed preparing and charging system | |
| CN211338771U (en) | Cosmetic liquid filling device of plant active ingredient |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20100127 |