CN1954079A - 含有作为构成要素的长链高不饱和脂肪酸的磷脂质的制造方法及其应用 - Google Patents
含有作为构成要素的长链高不饱和脂肪酸的磷脂质的制造方法及其应用 Download PDFInfo
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- CN1954079A CN1954079A CNA2005800065560A CN200580006556A CN1954079A CN 1954079 A CN1954079 A CN 1954079A CN A2005800065560 A CNA2005800065560 A CN A2005800065560A CN 200580006556 A CN200580006556 A CN 200580006556A CN 1954079 A CN1954079 A CN 1954079A
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- phospholipid
- lcpufa
- lipid
- acid
- thalline
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Classifications
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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- C07F9/02—Phosphorus compounds
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- C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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Landscapes
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- Life Sciences & Earth Sciences (AREA)
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- Fats And Perfumes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
提取剂 | 组成(体积混合比) |
正己烷正己烷/乙醇混合溶剂 a″ b″ c″ d″ e乙醇三氯甲烷/甲醇混合溶剂 | 正己烷∶乙醇=6∶0正己烷∶乙醇=4∶1正己烷∶乙醇=4∶2正己烷∶乙醇=3∶3正己烷∶乙醇=2∶4正己烷∶乙醇=1∶4正己烷∶乙醇=0∶6三氯甲烷∶甲醇=2∶1 |
提取剂(有机溶剂) | 提取的脂肪酸的脂质(mg/g脱脂菌体) | PL的总脂肪酸中LCPUFA的含有率(%) | ||
PL | TG | AA | DGLA | |
正己烷正己烷/乙醇混合溶剂 a″ b″ c″ d″ e乙醇三氯甲烷/甲醇混合溶剂 | 0.020.024.424.119.916.416.324.9 | 35.040.040.443.445.241.842.066.1 | -43.043.742.542.742.541.740.4 | -2.82.52.52.62.62.62.5 |
脱脂菌体 | 组分 | 提取的脂肪酸的脂质(mg) | 各组分的总脂肪酸中LCPUFA的比例(%) | 提取的脂质中的LCPUFA(mg) | ||||
AA | DGLA | 合计 | AA | DGLA | 合计 | |||
A-1 | PL | 22.4 | 42.5 | 2.5 | 45.0 | 9.52 | 0.56 | 10.1 |
TG | 98.3 | 42.0 | 2.5 | 44.5 | 41.3 | 2.46 | 43.8 | |
A-2 | PL | 23.0 | 42.5 | 2.6 | 45.1 | 9.78 | 0.60 | 10.4 |
TG | 46.2 | 42.0 | 2.5 | 44.5 | 19.4 | 1.16 | 20.6 | |
A-3 | PL | 23.0 | 42.5 | 2.6 | 45.1 | 9.78 | 0.60 | 10.4 |
TG | 26.8 | 41.8 | 2.5 | 44.3 | 11.2 | 0.67 | 11.9 | |
A-4 | PL | 22.8 | 42.4 | 2.6 | 45.0 | 9.67 | 0.59 | 10.3 |
TG | 19.7 | 40.9 | 2.5 | 43.4 | 8.06 | 0.49 | 8.55 |
组分 | 脂肪酸的重量比(%) | 各组分的总脂肪酸中的LCPUFA的比例(%) | |
AA | DGLA | ||
P CP EP SP IG L | 58.925.13.15.47.5 | 53.733.923.522.218.3 | 3.11.71.43.31.4 |
脱脂菌体 | 组分 | 提取的脂肪酸的脂质(mg) | 各组分的总脂肪酸中的LCPUFA的比例(%) | 提取的脂质中的LCPUFA(mg) | |||
AA | DGLA | MeadAcid | LCPUFA合计 | ||||
B | PL | 20.0 | 20.2 | 2.3 | 0.0 | 22.5 | 4.50 |
TG | 50.2 | 9.6 | 1.9 | 0.0 | 11.5 | 5.77 | |
C | PL | 22.2 | 0.3 | 45.6 | 0.0 | 45.9 | 10.2 |
TG | 43.0 | 0.0 | 35.7 | 0.0 | 35.7 | 15.4 | |
D | PL | 22.3 | 0.0 | 0.0 | 31.1 | 31.1 | 6.94 |
TG | 42.0 | 0.0 | 0.0 | 25.8 | 25.8 | 10.8 | |
E | PL | 21.5 | 34.7 | 3.1 | 0.0 | 37.8 | 8.13 |
TG | 42.5 | 20.0 | 2.5 | 0.0 | 22.5 | 9.56 |
组分 | 脂肪酸的重量比(%) | 各组分的总脂肪酸中的LCPUFA的比例(%) | |
AA | DGLA | ||
P CP EP SP IG L | 56.228.510.24.40.7 | 30.015.815.611.68.5 | 3.12.21.11.91.3 |
组分 | 脂肪酸的重量比(%) | 各组分的总脂肪酸中的LCPUFA的比例(%) | |
AA | DGLA | ||
P CP EP SP IG L | 60.223.112.23.21.3 | 17.910.08.89.58.5 | 2.11.71.00.91.1 |
Claims (36)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP056928/2004 | 2004-03-01 | ||
JP2004056928 | 2004-03-01 | ||
PCT/JP2005/003344 WO2005083101A1 (ja) | 2004-03-01 | 2005-02-28 | 長鎖高度不飽和脂肪酸を構成要素として含むリン脂質の製造方法、およびその利用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1954079A true CN1954079A (zh) | 2007-04-25 |
CN1954079B CN1954079B (zh) | 2012-08-08 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800065560A Expired - Fee Related CN1954079B (zh) | 2004-03-01 | 2005-02-28 | 含有作为构成要素的长链高不饱和脂肪酸的磷脂质的制造方法及其应用 |
Country Status (11)
Country | Link |
---|---|
US (2) | US7847113B2 (zh) |
EP (1) | EP1731616A4 (zh) |
JP (1) | JP4850060B2 (zh) |
KR (2) | KR101194236B1 (zh) |
CN (1) | CN1954079B (zh) |
AU (2) | AU2005217300B2 (zh) |
CA (1) | CA2558255C (zh) |
MY (1) | MY148070A (zh) |
SG (1) | SG150563A1 (zh) |
TW (2) | TWI419649B (zh) |
WO (1) | WO2005083101A1 (zh) |
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-
2005
- 2005-02-28 CN CN2005800065560A patent/CN1954079B/zh not_active Expired - Fee Related
- 2005-02-28 AU AU2005217300A patent/AU2005217300B2/en not_active Ceased
- 2005-02-28 WO PCT/JP2005/003344 patent/WO2005083101A1/ja active Application Filing
- 2005-02-28 KR KR1020117027960A patent/KR101194236B1/ko active IP Right Grant
- 2005-02-28 US US10/591,329 patent/US7847113B2/en not_active Expired - Fee Related
- 2005-02-28 KR KR1020067020350A patent/KR101194235B1/ko active IP Right Grant
- 2005-02-28 JP JP2006510509A patent/JP4850060B2/ja not_active Expired - Fee Related
- 2005-02-28 EP EP05719661A patent/EP1731616A4/en not_active Withdrawn
- 2005-02-28 SG SG200901459-8A patent/SG150563A1/en unknown
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- 2005-03-01 MY MYPI20050834A patent/MY148070A/en unknown
- 2005-03-01 TW TW100144365A patent/TWI419649B/zh not_active IP Right Cessation
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Cited By (13)
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CN103200827A (zh) * | 2010-08-12 | 2013-07-10 | 营养治疗公司 | 用于保持健康、以及治疗急性和慢性疾病的脂类补充剂 |
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US11253531B2 (en) | 2011-08-11 | 2022-02-22 | Nutritional Therapeutics, Inc. | Lipid supplements for reducing nerve action potentials |
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Also Published As
Publication number | Publication date |
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TW201210513A (en) | 2012-03-16 |
EP1731616A1 (en) | 2006-12-13 |
KR20120002612A (ko) | 2012-01-06 |
CA2558255A1 (en) | 2005-09-09 |
KR101194236B1 (ko) | 2012-10-29 |
WO2005083101A1 (ja) | 2005-09-09 |
JP4850060B2 (ja) | 2012-01-11 |
AU2005217300A1 (en) | 2005-09-09 |
KR20060130699A (ko) | 2006-12-19 |
AU2005217300B2 (en) | 2010-12-02 |
CA2558255C (en) | 2014-01-14 |
US7968737B2 (en) | 2011-06-28 |
US7847113B2 (en) | 2010-12-07 |
AU2011200414A1 (en) | 2011-02-24 |
TWI378793B (en) | 2012-12-11 |
SG150563A1 (en) | 2009-03-30 |
JPWO2005083101A1 (ja) | 2007-08-02 |
US20080020124A1 (en) | 2008-01-24 |
TWI419649B (zh) | 2013-12-21 |
CN1954079B (zh) | 2012-08-08 |
EP1731616A4 (en) | 2011-08-17 |
US20100317622A1 (en) | 2010-12-16 |
TW200533338A (en) | 2005-10-16 |
KR101194235B1 (ko) | 2012-10-29 |
MY148070A (en) | 2013-02-28 |
AU2011200414B2 (en) | 2011-12-15 |
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