CN1895188A - Intra-ocular camera head for visual prosthesis - Google Patents
Intra-ocular camera head for visual prosthesis Download PDFInfo
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- CN1895188A CN1895188A CN 200610027984 CN200610027984A CN1895188A CN 1895188 A CN1895188 A CN 1895188A CN 200610027984 CN200610027984 CN 200610027984 CN 200610027984 A CN200610027984 A CN 200610027984A CN 1895188 A CN1895188 A CN 1895188A
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- 239000007943 implant Substances 0.000 description 7
- 230000003287 optical effect Effects 0.000 description 5
- 238000002513 implantation Methods 0.000 description 4
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Abstract
An intra-ocular camera head for artificial visual body features that a gradient index lens and CMOS image sensor are connected in seamless mode, and fully wrapped by an annular solar cell for supplying electric power to them. Its advantages are small axial size and no need of battery.
Description
Technical field
The present invention relates to a kind of device of technical field of medical instruments, specifically, is a kind of intra-ocular camera head that is used for vision prosthesis.
Background technology
Developed the camera system that many kinds adopt solid-state imager in recent years, images acquired information that can be real-time is in aspect extensive uses such as medical treatment, monitoring, safety.But they are in order to satisfy the needs of various application, and pixel, resolution are very high usually, the function complexity, and size is big, and the power consumption height can not satisfy the requirement of vision prosthesis.
Existing camera system adopts ordinary lens as optical lens usually, and its focal length is long, and size is big, is difficult to processing, be not easy to implant, and the production cost height.
At present, in the miniature imaging device, adopt button cell as power supply usually, its volume is urinated in implantation.But its weak point is: button cell contains harmful material, and it is detained the long time in human body obviously be inappropriate, and when running down of battery, changes battery and also comparatively bother.
Find through literature search prior art, the Chinese invention patent application number is CN03262832.3, open day be JIUYUE in 2004 15 days, this patent readme is: " minisize pick-up head, it is made up of optical lens, photographic head, it is characterized in that: optical lens is a GRIN Lens; the GRIN Lens front end face is the plane; rear end face is a sphere, and the GRIN Lens imaging surface has the CCD photographic head, GRIN Lens front end face and optical axis vertical fixing have smallcolumn diaphragm." its weak point is: 1. adopt the CCD photographic head as image device; 2. GRIN Lens (being gradient-index lens) is not considered the shortening focal length; to realize seamless combination; so this system has just realized microminiaturization to a certain extent with CCD; but be aimed at the needs of vision prosthesis intra-ocular camera head; the obvious volume of this system is excessive, is not easy to implantation.And this system does not consider power supply design part.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, propose a kind of intra-ocular camera head that is used for vision prosthesis, make its size little, low in energy consumption, satisfy the needs of vision prosthesis imaging, and implantable ophthalmic, the rotation by people's eyeball realizes scanning automatically.
The present invention is achieved by the following technical solutions, and the intra-ocular camera head that is used for vision prosthesis of the present invention comprises: gradient-index lens, CMOS (CMOS complementary metal-oxide-semiconductor) imageing sensor, annular solaode.Gradient-index lens and cmos image sensor seamless combination, annular solaode is wrapped in its inside fully with gradient-index lens and cmos image sensor, and system forms a whole.The annular solaode is connected with cmos image sensor, for cmos image sensor provides stable running voltage.
Described gradient-index lens, its diameter are between 0.35mm-0.6mm, and length is between 1.3mm-3mm, and gradient-index lens covers the front surface of photosensitive array in the cmos image sensor as optical lens, converges light for it provides.Gradient-index lens adopts gradient index fibre, and size is little, and focal length is short, is convenient to install, and can realize and the seamless combination of cmos image sensor, has further dwindled the axial dimension of camera system, is convenient to ophthalmic and implants.
Described cmos image sensor comprises: photosensitive array, control circuit, pre-process circuit, analog digital conversion (A/D) circuit.The output of control circuit is connected to the signal input part of photosensitive array, the signal output part of photosensitive array is connected to the input of pre-process circuit, the outfan of pre-process circuit is connected to analog to digital conversion circuit, control circuit produces control signal and gives photosensitive array, photosensitive array carries out exporting and the proportional signal of telecommunication of light intensity after the opto-electronic conversion, this signal at first outputs to pre-process circuit, and analogue signal is after treatment exported to analog to digital conversion circuit, carries out exporting digital signal after the analog digital conversion.
Described photosensitive array, its resolution are 25 * 25, total pixel number 625, and the quick unit size scope of statuette is between 6um * 6um-10um * 10um, and photosensitive area is between 0.15mm * 0.15mm-0.25mm * 0.25mm.The element of photosensitive array promptly as quick unit, adopts active structure, does not have the colored filter of covering on the pixel surface, promptly only produces the gray value signal.The low pixel cmos image sensor of design satisfying on the requirement basis of object identification, had both reduced size, had reduced power consumption again, was convenient to ophthalmic and implanted.The cmos image sensor overall dimensions is between 0.25mm * 0.25mm-0.45mm * 0.45mm, and Diagonal Dimension is between 0.35mm-0.6mm, and thickness is between 0.3mm-0.6mm.Frame frequency between 24fps-30fps, running voltage 2.5V, power consumption is exported 8 position digital signals between 0.5mW-1.0mW.
Described annular solaode, its internal diameter between 0.35mm-0.6mm, external diameter between 4.0mm-8.0mm, thickness between 1.6mm-3.6mm, conversion efficiency 15%-23%, output can reach 1mW.The annular solaode is wrapped in around gradient-index lens and the cmos image sensor, for it provides stable 2.5V running voltage as circumscribed circle.Solar cell design circularizes, and its circular inner edge is convenient to wrap up columniform gradient-index lens; And the human body pupil is circular, and the slick outward flange of solaode is more suitable in implanting pupil.Size is little, can charge automatically, makes things convenient for the ophthalmic of system to implant, and in case removes the trouble of changing battery after implanting from.
Among the present invention; the gradient-index lens diameter is between 0.35mm-0.6mm; the cmos image sensor catercorner length is between 0.35mm-0.6mm; guarantee during design that both sizes are in full accord; seamless combination; annular solaode internal diameter size is between 0.35mm-0.6mm; guarantee that itself and gradient-index lens diameter and the cornerwise length of cmos image sensor are in full accord; it is wrapped in around gradient-index lens and the cmos image sensor fully with external circular formula; both played the effect of protection gradient-index lens; encapsulation is provided again, has formed a total system.Size maximum constraints of the present invention is at external diameter 8.00mm, length 3.6mm, and I reaches external diameter 4.0mm, length 1.6mm, according to the size of human body pupil size, this system can implant ophthalmic as can be known, realizes camera function.
Description of drawings
Fig. 1 is the structural representation that the present invention is used for the intra-ocular camera head of vision prosthesis.
Fig. 2 is the profile that the present invention is used for the intra-ocular camera head of vision prosthesis.
Fig. 3 is a cmos image sensor structured flowchart among the present invention.
Fig. 4 is the structure chart of the photosensitive array of cmos image sensor among the present invention.
The specific embodiment
As shown in Figure 1, the present invention's intra-ocular camera head of being used for vision prosthesis comprises: gradient-index lens 1, cmos image sensor 2, annular solaode 3.Gradient-index lens 1 and cmos image sensor 2 seamless combination, annular solaode 3 is wrapped in its inside fully with gradient-index lens 1 and cmos image sensor 2, annular solaode 3 is connected with cmos image sensor 2, for cmos image sensor 2 provides stable running voltage.
As shown in Figure 2, gradient-index lens 1 diameter is between 0.35mm-0.6mm, cmos image sensor 2 Diagonal Dimension are between 0.35mm-0.6mm, make both sizes in full accord, seamless combination together, annular solaode 3 internal diameters are between 0.35mm-0.6mm, in full accord with gradient-index lens 1 diameter and cmos image sensor 2 cornerwise sizes, as circumscribed circle, be wrapped in the outside fully, do as a whole implantation pupil inside.Cmos image sensor 2 thickness are between 0.3mm-0.6mm, the length of gradient-index lens 1 is between 1.3mm-3mm, the thickness of annular solaode 3 is between 1.6mm-3.6mm, make the length of annular solaode 3 equal the length of gradient-index lens 1 and the thickness sum of cmos image sensor 2 during design, it can be wrapped in its inside to gradient-index lens 1 and cmos image sensor 2 just fully like this, is convenient to install and implant.
According to the calculating of schematic eye, suppose to estimate that the vision of recovering is 0.1, then the minimum pixel size of cmos image sensor 2 must not be less than 6um.Pixel Dimensions is big more, and the ability of catching light is strong more, and picture quality is good more, but difficult more manufacturing, production cost is high more simultaneously, takes all factors into consideration, and the minimum pixel size range of design cmos image sensor 2 is between 6um * 6um-10um * 10um.
Show after deliberation, for the blind person, only need 25 * 25, i.e. 625 total pixel numbers just can recognition object.The photosensitive array of design cmos image sensor 2 is 25 * 25 like this, and lower pixel count had both reduced the size of imageing sensor 2, had reduced its power consumption again.In the research primary stage, selected lower pixel count, if require from now on to improve, can further improve the pixel of imageing sensor.Simultaneously,, only consider black white image, therefore do not having the covering colored filter as quick cell surface, output gray level value image in the research primary stage.
Through calculating, the photosensitive area of cmos image sensor is between 0.15mm * 0.15mm-0.25mm * 0.25mm, add some other treatment circuit of its inside, the size restrictions of expection cmos image sensor 2 is between 0.25mm * 0.25mm-0.45mm * 0.45mm, Diagonal Dimension is between 0.35mm-0.6mm, and thickness is between 0.3mm-0.6mm.
According to people's physiological characteristics, when the refresh rate of image reached 5fps, the people began to feel that image is active; And when reaching 24fps, the people feels that image is fully continuous and smooth, and the employed frame frequency of film is exactly 24fps, so the frame frequency of video signal should be more than or equal to 24Hz.In theory, frame frequency is high more good more, but frame frequency is high more, and also high more to the requirement of circuit, technology is complicated more, and the post-processed difficulty is high more, and cost is high more, and under the situation about taking all factors into consideration, the frame frequency of design cmos image sensor 2 is between 24fps-30fps.In this case, data transmission rate is about 1.9Mbit/s (consideration is output as 8 position digital signals, under the situation of 30fps).
As shown in Figure 3, the functional module of described cmos image sensor comprises: photosensitive array, control circuit, pre-process circuit, analog-digital conversion a/d circuit.Wherein photosensitive array is the core of imageing sensor, and image information is carried out opto-electronic conversion, the output signal of telecommunication.Control circuit is finished horizontal vertical control, sequence circuit produces, and functions such as automatic exposure control make imageing sensor carry out image output under certain time sequence.Pre-process circuit carries out preliminary treatment to the analogue signal of output, comprises functions such as automatic gain control, filtering.The analog-digital conversion a/d circuit carries out digital translation to the analogue signal after handling, and exports 8 gray value digital signals.Control circuit produces number control signal and gives photosensitive array, photosensitive array is exported after carrying out opto-electronic conversion under certain control and the proportional signal of telecommunication of light intensity, this signal at first outputs to pre-process circuit, analogue signal is after treatment exported to analog to digital conversion circuit, carries out exporting digital signal after the analog digital conversion.
As shown in Figure 4, photosensitive array in the described cmos image sensor 2 comprises: 25H * 25V total pixel number, it is arranged in the square formation of 25H * 25V by X and Y direction as quick unit, in the square formation each all has its address on X, Y all directions as quick unit, can be selected by horizontal vertical control respectively.The quick unit of picture adopts active structure, and promptly initiatively as quick cellular construction, each all passed through amplification as quick unit after, just by the output of field effect transistor analog switch, fixed pattern noise reduced greatly, and the signal to noise ratio of picture signal but significantly improves.Only require in vision prosthesis to obtain black white image that therefore need not to cover colored filter as quick cell surface, directly the output gray level value signal obtains black white image.
Gradient-index lens 1 is with the difference of ordinary lens: 1. it not only can make the light of radially transmission produce refraction, and its index distribution that radially reduces gradually, can realize smoothed and successive the converging to a bit of emergent ray; 2. logical luminous efficiency height, processing easily, two ends are slick plane, are convenient to install; 3. diameter is little, and overall dimensions is little, and the focal length weak point can reach 0.5mm simultaneously, is convenient to implant ophthalmic.
Here require gradient-index lens 1 overall dimensions to be, diameter is consistent with the Diagonal Dimension of cmos image sensor 2, between 0.35mm-0.6mm, length between 1.3mm-3mm, numerical aperture 0.46, intercept 0.25P.When selecting intercept 0.25P, converge to the rear end face of lens from the incident parallel rays of lens front end face after GRIN Lens, cmos image sensor 2 is directly installed on rear end face, can shorten the axial dimension of intra-ocular camera head like this.
Owing to the finite energy that solaode provides, must reduce the energy consumption of cmos image sensor 2 as far as possible.Therefore pick off adopts the 2.5V low-work voltage, and internal circuit configuration is simple, can realize low-power consumption with its power consumption constraints between 0.5mW-1mW.
Solar cell sizes is little, is convenient to implant, and can charge automatically, can remove the trouble of changing battery from behind the implantation ophthalmic, and have no side effect, and is safer, little to the human injury.The conversion efficiency of present common monocrystaline silicon solar cell is 15%, and laboratory internal conversion efficient can reach 23%.The Diagonal Dimension of cmos image sensor 2 is between 0.35mm-0.6mm, designing annular solaode 3 is of a size of, the catercorner length of the diameter of internal diameter and gradient-index lens 1 and cmos image sensor 2 is in full accord, between 0.35mm-0.6mm, external diameter is between 4.0mm-8.0mm, make its thickness equal the length of gradient-index lens 1 and the thickness sum of cmos image sensor 2 during design, between 1.6mm-3.6mm, its output can reach 1mW like this, satisfies cmos image sensor 2 job requirements.It is designed to annular, and interior circle is convenient to be installed with gradient-index lens 1 and cmos image sensor 2 combinations, and the cylindrical smooth edges is convenient to be implanted into ophthalmic.Simultaneously its thickness can wrap up gradient-index lens 1 and cmos image sensor 2 portion within it fully, has both played the effect of protection, and encapsulation is provided again, forms a total system.
Claims (6)
1. intra-ocular camera head that is used for vision prosthesis, comprise: gradient-index lens (1), cmos image sensor (2), annular solaode (3), it is characterized in that, gradient-index lens (1) and cmos image sensor (2) seamless combination, annular solaode (3) is wrapped in its inside fully with gradient-index lens (1) and cmos image sensor (2), annular solaode (3) is connected with cmos image sensor (2), for cmos image sensor (2) provides stable running voltage.
2. the intra-ocular camera head that is used for vision prosthesis according to claim 1, it is characterized in that, described gradient-index lens (1), the Diagonal Dimension of diameter and cmos image sensor (2) is in full accord, between 0.35mm-0.6mm, length between 1.3mm-3mm, numerical aperture 0.46, intercept 0.25P.
3. the intra-ocular camera head that is used for vision prosthesis according to claim 1, it is characterized in that, described cmos image sensor (2), comprise: photosensitive array, control circuit, pre-process circuit, analog to digital conversion circuit, the output of control circuit is connected to the signal input part of photosensitive array, the signal output part of photosensitive array is connected to the input of pre-process circuit, the outfan of pre-process circuit is connected to analog to digital conversion circuit, control circuit produces control signal and gives photosensitive array, photosensitive array carries out exporting and the proportional signal of telecommunication of light intensity after the opto-electronic conversion, this signal at first outputs to pre-process circuit, analogue signal is after treatment exported to analog to digital conversion circuit, carries out exporting digital signal after the analog digital conversion.
4. the intra-ocular camera head that is used for vision prosthesis according to claim 3, it is characterized in that, described photosensitive array, its resolution is 25 * 25, total pixel number 625, and the quick unit size scope of statuette is between 6um * 6um-10um * 10um, photosensitive area is between 0.15mm * 0.15mm-0.25mm * 0.25mm, the quick unit of picture adopts active structure, does not have the colored filter of covering on the pixel surface, promptly only produces the gray value signal.
5. according to claim 1 or the 3 described intra-ocular camera heads that are used for vision prosthesis, it is characterized in that, described cmos image sensor (2), its overall dimensions is between 0.25mm * 0.25mm-0.45mm * 0.45mm, and Diagonal Dimension is between 0.35mm-0.6mm, and thickness is between 0.3mm-0.6mm, frame frequency is between 24fps-30fps, running voltage 2.5V, power consumption is exported 8 position digital signals between 0.5mW-1.0mW.
6. the intra-ocular camera head that is used for vision prosthesis according to claim 1, it is characterized in that, described annular solaode (3), the Diagonal Dimension of the diameter of its internal diameter and gradient-index lens (1) and cmos image sensor (2) is in full accord, between 0.35mm-0.6mm, external diameter is between 4.0mm-8.0mm, the thickness sum of guaranteeing the length of its thickness and gradient-index lens (1) and cmos image sensor (2) is consistent, between 1.6mm-3.6mm, conversion efficiency 15%-23%, output can reach 1mW.
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| CNB2006100279848A CN100444812C (en) | 2006-06-22 | 2006-06-22 | Intra-ocular camera head for visual prosthesis |
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| CNB2006100279848A CN100444812C (en) | 2006-06-22 | 2006-06-22 | Intra-ocular camera head for visual prosthesis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101915975A (en) * | 2010-06-25 | 2010-12-15 | 浙江大学 | Variable-focus human eyeball imitation structure driven by linear performer |
| CN103272329A (en) * | 2013-05-06 | 2013-09-04 | 上海交通大学 | Artificial vision prosthetic device with wireless energy transmission function |
| CN107330368A (en) * | 2017-05-27 | 2017-11-07 | 芜湖星途机器人科技有限公司 | The robot recognition of face device of tilting multi-cam |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2016378A1 (en) * | 1970-04-06 | 1971-11-04 | Mengeier, Hermann, Dr., 4000 Düsseldorf | Process for artificial vision and eye prosthesis for performing this process |
| US4551149A (en) * | 1982-02-16 | 1985-11-05 | Michael Sciarra | Prosthetic vision system |
| US6658299B1 (en) * | 2000-01-04 | 2003-12-02 | William H. Dobelle | Artificial system for vision and the like |
| MXPA03004320A (en) * | 2000-11-16 | 2005-01-25 | Polyvalor Sec | Body electronic implant and artificial vision system thereof. |
| US7001427B2 (en) * | 2002-12-17 | 2006-02-21 | Visioncare Ophthalmic Technologies, Inc. | Intraocular implants |
| CN2640411Y (en) * | 2003-09-16 | 2004-09-15 | 西安北方光电有限公司 | Micro pick-up head |
| WO2006015315A2 (en) * | 2004-07-30 | 2006-02-09 | University Of Rochester Medical Center | Intraocular video system |
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2006
- 2006-06-22 CN CNB2006100279848A patent/CN100444812C/en active Active - Reinstated
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101915975A (en) * | 2010-06-25 | 2010-12-15 | 浙江大学 | Variable-focus human eyeball imitation structure driven by linear performer |
| CN101915975B (en) * | 2010-06-25 | 2012-01-04 | 浙江大学 | Variable-focus human eyeball imitation structure driven by linear performer |
| CN103272329A (en) * | 2013-05-06 | 2013-09-04 | 上海交通大学 | Artificial vision prosthetic device with wireless energy transmission function |
| CN103272329B (en) * | 2013-05-06 | 2015-05-20 | 上海交通大学 | Artificial vision prosthetic device with wireless energy transmission function |
| CN107330368A (en) * | 2017-05-27 | 2017-11-07 | 芜湖星途机器人科技有限公司 | The robot recognition of face device of tilting multi-cam |
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