CN1875006B - 氟甲基取代的杂环的制备方法 - Google Patents

氟甲基取代的杂环的制备方法 Download PDF

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Publication number
CN1875006B
CN1875006B CN2004800322480A CN200480032248A CN1875006B CN 1875006 B CN1875006 B CN 1875006B CN 2004800322480 A CN2004800322480 A CN 2004800322480A CN 200480032248 A CN200480032248 A CN 200480032248A CN 1875006 B CN1875006 B CN 1875006B
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CN
China
Prior art keywords
alkyl
formula
chlorine
substituted
hydrogen
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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CN2004800322480A
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English (en)
Chinese (zh)
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CN1875006A (zh
Inventor
R·兰茨施
S·帕奇诺克
F·梅美尔
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Bayer Intellectual Property GmbH
Bayer CropScience AG
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Bayer CropScience AG
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Publication of CN1875006A publication Critical patent/CN1875006A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CN2004800322480A 2003-10-31 2004-10-19 氟甲基取代的杂环的制备方法 Expired - Lifetime CN1875006B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10351088A DE10351088A1 (de) 2003-10-31 2003-10-31 Verfahren zum Herstellen von fluormethyl-substituierten Heterocyclen
DE10351088.5 2003-10-31
PCT/EP2004/011809 WO2005044804A1 (de) 2003-10-31 2004-10-19 Verfahren zum herstellen von fluormethyl-substituierten heterocyclen

Publications (2)

Publication Number Publication Date
CN1875006A CN1875006A (zh) 2006-12-06
CN1875006B true CN1875006B (zh) 2011-12-21

Family

ID=34530016

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800322480A Expired - Lifetime CN1875006B (zh) 2003-10-31 2004-10-19 氟甲基取代的杂环的制备方法

Country Status (14)

Country Link
US (1) US7501527B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP1682515B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP4936895B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR101123745B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1875006B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BRPI0416112A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE10351088A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK1682515T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2524597T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL175148A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2006DE01990A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MXPA06004605A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI359141B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2005044804A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE455105T1 (de) * 2006-11-03 2010-01-15 Basf Se Verfahren zur herstellung von difluormethylpyrazolylcarboxylaten
KR20090107506A (ko) * 2006-12-21 2009-10-13 바스프 에스이 플루오로메틸-치환된 헤테로시클릭 화합물의 제조 방법
EP2164831B1 (de) 2007-06-01 2013-07-17 Basf Se Verfahren zur herstellung n-substituierter (3-dihalomethyl-1-methyl-pyrazol-4-yl)carboxamide
ATE520667T1 (de) * 2007-06-15 2011-09-15 Basf Se Verfahren zur herstellung difluormethylsubstituierter pyrazolverbindungen
EP2181087B1 (en) 2007-08-16 2015-10-14 Solvay Sa Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids
UA102386C2 (ru) 2008-02-29 2013-07-10 Басф Се Способ получения алкил-2-алкоксимэтилен-4,4-дифтор-3-оксобутиратов
CN102015653B (zh) 2008-05-02 2013-09-11 巴斯夫欧洲公司 制备卤素取代的2-(氨基亚甲基)-3-氧代丁酸酯的方法
US8314233B2 (en) 2008-05-02 2012-11-20 Basf Se Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters
EA019312B1 (ru) 2008-05-05 2014-02-28 Басф Се Способ получения 1,3,4-замещённых пиразольных соединений
MX317270B (es) * 2008-05-08 2014-01-20 Basf Se Procedimiento para la obtencion de arilcarboxamidas.
EP2307384B1 (en) 2008-07-21 2012-04-25 Basf Se Process for preparing 1,3-disubstituted pyrazolecarboxylic esters
US8981116B2 (en) 2010-07-23 2015-03-17 Solvay Sa Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids
FR2975992B1 (fr) * 2011-06-01 2013-11-08 Rhodia Operations Procede de preparation d'un compose fluoromethylpyrazole sous forme acide carboxylique ou derivee
FR2975990B1 (fr) 2011-06-01 2013-05-24 Rhodia Operations Procede de preparation d'un compose organique fluore
US20140128617A1 (en) * 2011-06-21 2014-05-08 Wahed Ahmed Moradi Method for producing pyrazolylcarboxanilides
CN105008330A (zh) * 2013-02-15 2015-10-28 先正达参股股份有限公司 用于制备双-二卤代烷基吡唑的方法
DK3046908T3 (en) * 2013-09-20 2017-10-02 Bayer Cropscience Ag METHOD FOR PREPARING 5-FLOUR-1-ALKYL-3-FLOURALKYL-1H-PYRAZOL-4-CARBALDEHYDE.
CN106045910B (zh) 2016-08-15 2017-10-10 浙江永太科技股份有限公司 一种3‑(二氟甲基)‑1‑甲基‑1h‑吡唑‑4‑羧酸的合成方法
CN115572210B (zh) * 2022-12-08 2023-03-21 暨南大学 一种(1,2,2,2-四氟乙基)芳烃衍生物及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3934924A1 (de) * 1989-10-20 1991-04-25 Huels Chemische Werke Ag Verfahren zur herstellung von 4-alkoxycarbonyl-3-chlormethyl-2h-pyrazolen
US5675016A (en) * 1995-12-01 1997-10-07 Bayer Aktiengesellschaft Process for the preparation of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides
US6319940B1 (en) * 1996-07-24 2001-11-20 Bayer Aktiengesellschaft Carbanilides used as pesticides
WO2003070705A1 (de) * 2002-02-19 2003-08-28 Bayer Cropscience Aktiengesellschaft Disubstituierte pyrazolylcarboxanilide

Family Cites Families (7)

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JPS6357568A (ja) * 1982-04-16 1988-03-12 ザ　ダウ　ケミカル　カンパニ− 液相ハロゲン交換反応における触媒再使用
DE3400168A1 (de) * 1984-01-04 1985-07-11 Bayer Ag, 5090 Leverkusen 5-halogenalkyl-1,3,4-thiadiazol-2-yloxyacetamide
US5126275A (en) * 1990-09-19 1992-06-30 Miles Inc. Analytical method using tetrazolium salt indicators having a reflectance plateau
US5093347A (en) * 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
US5223526A (en) * 1991-12-06 1993-06-29 Monsanto Company Pyrazole carboxanilide fungicides and use
DE4231517A1 (de) * 1992-09-21 1994-03-24 Basf Ag Carbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen
JP3533134B2 (ja) * 1999-02-15 2004-05-31 三井化学株式会社 フッ素化剤及びその製法と使用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3934924A1 (de) * 1989-10-20 1991-04-25 Huels Chemische Werke Ag Verfahren zur herstellung von 4-alkoxycarbonyl-3-chlormethyl-2h-pyrazolen
US5675016A (en) * 1995-12-01 1997-10-07 Bayer Aktiengesellschaft Process for the preparation of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides
US6319940B1 (en) * 1996-07-24 2001-11-20 Bayer Aktiengesellschaft Carbanilides used as pesticides
WO2003070705A1 (de) * 2002-02-19 2003-08-28 Bayer Cropscience Aktiengesellschaft Disubstituierte pyrazolylcarboxanilide

Also Published As

Publication number Publication date
CN1875006A (zh) 2006-12-06
MXPA06004605A (es) 2006-07-20
ES2524597T3 (es) 2014-12-10
EP1682515B1 (de) 2014-10-01
IL175148A0 (en) 2006-09-05
DK1682515T3 (en) 2014-11-17
KR20060094534A (ko) 2006-08-29
TWI359141B (en) 2012-03-01
US20060276656A1 (en) 2006-12-07
JP4936895B2 (ja) 2012-05-23
TW200530189A (en) 2005-09-16
WO2005044804A1 (de) 2005-05-19
IL175148A (en) 2015-03-31
JP2007509871A (ja) 2007-04-19
BRPI0416112A (pt) 2007-01-02
EP1682515A1 (de) 2006-07-26
IN2006DE01990A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2007-07-13
DE10351088A1 (de) 2005-06-02
US7501527B2 (en) 2009-03-10
KR101123745B1 (ko) 2012-03-15

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Legal Events

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: BAYER CROP SCIENCE STOCK CORP.

Free format text: FORMER OWNER: BAYER CROP SCIENCE GMBH

Effective date: 20080118

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20080118

Address after: German Monheim

Applicant after: BAYER CROPSCIENCE AG

Address before: Frankfurt, Germany

Applicant before: BAYER CROPSCIENCE GmbH

C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: BAYER INTELLECTUAL PROPERTY GMBH

Free format text: FORMER OWNER: BAYER LANDWIRTSCHAFTLICHE KULTURPFLANZEN SCIENCE AG

Effective date: 20150402

TR01 Transfer of patent right

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CP03 Change of name, title or address

Address after: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789

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Effective date of registration: 20240112

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CX01 Expiry of patent term
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Granted publication date: 20111221