CN1850242A - Compounded mongolia medicine for treating diabetes and preparing method - Google Patents
Compounded mongolia medicine for treating diabetes and preparing method Download PDFInfo
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- CN1850242A CN1850242A CNA2006100546177A CN200610054617A CN1850242A CN 1850242 A CN1850242 A CN 1850242A CN A2006100546177 A CNA2006100546177 A CN A2006100546177A CN 200610054617 A CN200610054617 A CN 200610054617A CN 1850242 A CN1850242 A CN 1850242A
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Abstract
The present invention relates to a compound Chinese Mongolian medicine for effectively curing diabetes and its preparation method. It is made up by using Chinese medicinal materials of Chinese angelica root, typha pollen, leonurus, dianthus, bamboo leaf, black ant, seal's genitals, sea horse and dragon's blood as raw material and adding carboxymethyl cellulose sodium and magnesium stearate as excipient through a certain preparation process.
Description
Technical field
The present invention relates to Chinese herbal medicine, is a kind of compounded mongolia medicine and preparation method that is used for the treatment of diabetes.
Background technology
Diabetes are a kind of commonly encountered diseases, frequently-occurring disease, and the radical cure difficulty, present Therapeutic Method is still based on Drug therapy.Because diabetes pathological lesion process complexity, though Western medicine has better curative effect, but it is poor to effect a permanent cure, need take for a long time, and the thing followed is that side effect can not be ignored, payes attention to so adopt traditional Chinese medical science medical herbs that treatment of diabetes is obtained people day by day, as Chinese medicines such as SHENQI JIANGTANG KELI commonly used, though shown certain curative effect, say with clinical desired distance very far objectively, be not the medicine of ideal.So the invention discloses a kind of new compounded mongolia medicine, through clinic trial, practice confirms that hypoglycemic effect is remarkable, does not have any untoward reaction.
Summary of the invention
The present invention is the powder proved recipe with some treatment diabetes in the traditional mongolian medicine, pertinent regulations according to Mongolian medicine's basic theories and national new drug research, by pharmacodynamic experiment research and certain clinical verification, make again compatibility and enrich adjustment, and being mixed with compound preparation by a kind of brand-new process, its general purpose is the compounded mongolia medicine that a kind of good effect, cure rate height is provided, is mainly used to treat diabetes.
Compounded mongolia medicine of the present invention, see at present be first be developed be used for the treatment of diabetes mongolian medicine new drug, it is guidance with whole the sight with the pure and impure basic theories of separating of Mongolian medicine, following and transferring unit and rehabilitation liver, kidney stomach function regulating function is principle, and all medicine compositions of temperature, short pure and impure separation and rehabilitation function are mended in choosing.Whole development process is strict with national six kind new medicines research pertinent regulations, done comparatively authority's theory analysis with regard to the reasonability of prescription, extracts active ingredients and Study on Forming are sufficient orthogonal optimum seeking, set up the stabilized quality standard with comparatively advanced technological means, main pharmacodynamics and toxicological test, the research standard, credible result, the clinical research scheme is complete feasible.Its basic characteristics are to rely on strong body of the kidney invigorating and raising self sugar to be used to make blood sugar recovery normal.So, though it is slow but stable to take the back blood sugar reducing function, rehabilitation is firm, strong body the kidney invigorating is remarkable, simultaneously property, reproductive function there is obvious potentiation, patent medicine is named as " well must this clear sugar-tablet " by the mongolian medicine characteristic, is mainly used to the treatment of diabetes rehabilitation very promisingly, and can enlarge exploitation and use as health care medicine.
The present invention realizes its purpose by the following technical solutions:
(1) formation of preparation and weight portion are:
Radix Angelicae Sinensis 60 ~ 80 Pollen Typhaes 75 ~ 90 Herba Leonuris 70 ~ 85
Herba Dianthi 70 ~ 90 Herba Lophatheris 70 ~ 90 Formica fuscas 25 ~ 40
Testis et penis callorhini 20 ~ 30 Hippocampus 20 ~ 30 Sanguis Draxonis 10 ~ 20
Other joins compound carboxymethyl sodium cellulosate 0.5 ~ 1.0 and the type agent is applied in magnesium stearate 7 ~ 8 conducts.
(2) preparation technology's method of preparation:
Get Radix Angelicae Sinensis, Hippocampus, Testis et penis callorhini, Formica fusca and Sanguis Draxonis, be ground into fine powder, make conventional sterilization treatment;
Get Pollen Typhae, Herba Leonuri, Herba Dianthi and Herba Lophatheri, be ground into coarse powder, add 75% alcohol reflux 1 hour of 10 times of amounts, filter, will reclaim ethanol filtrate and be concentrated into thick extractum;
Get filterable medicinal residues and add 10 times of water gagings decoctions 30 minutes, filter, filtrate decompression is concentrated into thick extractum;
Merge two kinds of thick extractum, add the aforesaid Chinese medicine fine powder of crossing through sterilization treatment, stir, make 70 ℃ of vacuum dryings, pulverize, sieve;
At last, the adapted sodium carboxymethyl cellulose is granulated with 60% ethanol moistening, after the drying, joins the weight compacting of magnesium stearate with every 0.24g, and film coating promptly.
The concrete preparation technology of mongolian medicine of the present invention is provided by accompanying drawing.
Description of drawings
Fig. 1 is concrete preparation technology's flow chart of the present invention.
The specific embodiment
The present invention is as a kind of Mongolian medicinal preparation that is mainly used to treat diabetes, its basic characteristics are to rely on strong body of the kidney invigorating and raising self sugar to be used to make blood sugar recovery normal, whole development process is strict with national six kind new medicines research pertinent regulations, extracts active ingredients and moulding process all adopt orthogonal optimum seeking, and set up the stabilized quality standard by the technological means of emulating the advanced, credible result, good effect, rehabilitation is firm, and strong body the kidney invigorating is remarkable.Do the sample statistics through different medical record of sex difference, the age of clinic trial being randomly drawed 30 examples, total effective rate is more than 86.6%, and wherein, obvious effective rate reaches 54%, and administration time was 1 ~ 2 course of treatment, and be about 21 days 1 course of treatment.
Now lift one of them model case: certain patient wraps XX, man, 56 years old, cadre, go to a doctor in June, 2003, the main suit whole body is weak, dizzy soreness of waist half a year, thirsty frequent micturition, the three-many-one-little feature is obvious, and blood glucose (FPG) is 11.93mmol/L on an empty stomach, glucose in urine ++, so be diagnosed as diabetes.Take compounded mongolia medicine of the present invention, one time 4,2 times on the one, patient symptom obviously alleviates 11 days the time through taking medicine, FPG reduces to 9.82mmol/L, glucose in urine still ++.Continue to take medicine a course of treatment (21 days), FPG drops to 7.6mmol/L, glucose in urine+and, symptom disappears substantially.Through the continuation treatment of second course of treatment, recovery from illness.Drug withdrawal was followed up a case by regular visits to 1 year, did not see recurrence.
Optimum formula of the present invention is:
Radix Angelicae Sinensis 75 Pollen Typhaes 80 Herba Leonuris 80
Herba Dianthi 80 Herba Lophatheris 80 Formica fuscas 30
Testis et penis callorhini 25 Hippocampus 25 Sanguis Draxonis 15
Other joins compound carboxymethyl sodium cellulosate 0.7 and the type agent is applied in magnesium stearate 7.5 conducts.
Patent medicine of the present invention is tablet, and monolithic weight 0.24g composes name " well must this clear sugar-tablet ".
Its major function is: educate temperature, and pure and impure, blood sugar lowering, the kidney invigorating; Cure mainly: diabetes; Oral: one time 3～4,2 times on the one.
Each Chinese medicine ingredients all should satisfy the relevant regulations in the Pharmacopoeia of the People's Republic of China and the ministry standard among the present invention.
The present invention shows through drug efficacy study: have good blood sugar lowering effect, rehabilitation has positive effect for treatment of diabetes, does not have any untoward reaction.
The present invention's prescription can be expanded into a kind of health care medicine and use.
Claims (3)
1, a kind of compounded mongolia medicine for the treatment of diabetes, the formation of its preparation and weight portion are:
Radix Angelicae Sinensis 60 ~ 80 Pollen Typhaes 75 ~ 90 Herba Leonuris 70 ~ 85
Herba Dianthi 70 ~ 90 Herba Lophatheris 70 ~ 90 Formica fuscas 25 ~ 40
Testis et penis callorhini 20 ~ 30 Hippocampus 20 ~ 30 Sanguis Draxonis 10 ~ 20
Other joins compound carboxymethyl sodium cellulosate 0.5 ~ 1.0 and the type agent is applied in magnesium stearate 7 ~ 8 conducts.
2, a kind of compounded mongolia medicine for the treatment of diabetes according to claim 1, its optimum formula is:
Radix Angelicae Sinensis 75 Pollen Typhaes 80 Herba Leonuris 80
Herba Dianthi 80 Herba Lophatheris 80 Formica fuscas 30
Testis et penis callorhini 25 Hippocampus 25 Sanguis Draxonis 15
Other joins compound carboxymethyl sodium cellulosate 0.7 and the type agent is applied in magnesium stearate 7.5 conducts.
3, a kind of preparation method for the treatment of the compounded mongolia medicine of diabetes is characterized in that:
Get Radix Angelicae Sinensis, Hippocampus, Testis et penis callorhini, Formica fusca and Sanguis Draxonis, be ground into fine powder, make conventional sterilization treatment;
Get Pollen Typhae, Herba Leonuri, Herba Dianthi and Herba Lophatheri, be ground into coarse powder, add 75% alcohol reflux 1 hour of 10 times of amounts, filter, will reclaim ethanol filtrate and be concentrated into thick extractum;
Get filterable medicinal residues and add 10 times of water gagings decoctions 30 minutes, filter, filtrate decompression is concentrated into thick extractum;
Merge two kinds of thick extractum, add the aforesaid Chinese medicine fine powder of crossing through sterilization treatment and stir, 70 ℃ of vacuum dryings are pulverized, and sieve;
The adapted sodium carboxymethyl cellulose is granulated with 60% ethanol moistening, after the drying, joins magnesium stearate, with the weight compacting of every 0.24g, film coating.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100546177A CN100364596C (en) | 2006-02-06 | 2006-02-06 | Compounded mongolia medicine for treating diabetes and preparing method |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100546177A CN100364596C (en) | 2006-02-06 | 2006-02-06 | Compounded mongolia medicine for treating diabetes and preparing method |
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| Publication Number | Publication Date |
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| CN1850242A true CN1850242A (en) | 2006-10-25 |
| CN100364596C CN100364596C (en) | 2008-01-30 |
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| CNB2006100546177A Expired - Fee Related CN100364596C (en) | 2006-02-06 | 2006-02-06 | Compounded mongolia medicine for treating diabetes and preparing method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018020971A (en) * | 2016-08-03 | 2018-02-08 | 日本ハム株式会社 | Composition for enhancing expression of adiponectin |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087009A (en) * | 1993-08-05 | 1994-05-25 | 汪亚利 | Food for dietary of diabetic and compound method thereof |
| CN1243718A (en) * | 1998-08-04 | 2000-02-09 | 姜彬 | Chinese medicine for treating insulin-independent diabetes with special effect |
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2006
- 2006-02-06 CN CNB2006100546177A patent/CN100364596C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018020971A (en) * | 2016-08-03 | 2018-02-08 | 日本ハム株式会社 | Composition for enhancing expression of adiponectin |
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Assignee: Kailu County Chang Hui biotechnology limited liability company Assignor: Na Shengsang Contract fulfillment period: 2008.12.20 to 2013.12.19 Contract record no.: 2009150000030 Denomination of invention: Compounded mongolia medicine for treating diabetes and preparing method Granted publication date: 20080130 License type: Exclusive license Record date: 20091111 |
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Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.12.20 TO 2013.12.19; CHANGE OF CONTRACT Name of requester: KAILU EVER BRILLIANCE BIOTECHNOLOGY CO., LTD. Effective date: 20091111 |
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