CN1830494A - Medical hemodialysis filter - Google Patents

Medical hemodialysis filter Download PDF

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Publication number
CN1830494A
CN1830494A CN 200610054209 CN200610054209A CN1830494A CN 1830494 A CN1830494 A CN 1830494A CN 200610054209 CN200610054209 CN 200610054209 CN 200610054209 A CN200610054209 A CN 200610054209A CN 1830494 A CN1830494 A CN 1830494A
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housed
joint
connects
blood
reverse osmosis
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CN 200610054209
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CN100460026C (en
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高光勇
陈香美
文亮
任应祥
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SWS HEMODIALSIS CARE CO., LTD.
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Chongqing Shanwaishan Science & Technology Co Ltd
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Abstract

A medical filtering machine for the hemodialysis is composed of main body with console panel, blood loop consisting artery loop and vein loop, liquid-supplementing loop, water channel system and operation-control system. Said water channel system consists of reverse osmosis jointer, heat exchanger, heater, gear pump, deaerating unit, two concentrated liquid pumps, mixer, ion concentration monitor, volume balance and ultrafiltration unit, and endotoxin filter.

Description

Medical hemodialysis filter
Technical field
The present invention relates to a kind of armarium, in particular for removing the medical hemodialysis filter of source, patient inside and outside property and endogenous poisonous substance, refuse or other harmful substance.
Background technology
Hemodialysis (HD) and hemofiltration (HF) are the most widely used therapeutic modalities in blood purification field.And two kinds of treatment patterns all need hemodialyzer or transfusion filters to reach the purpose of removing toxin at last, they structurally do not have the difference of essence, all form by a large amount of hollow fibre pipes, these hollow fibre pipes are a kind of semipermeable membranes with high-permeability, middle small-molecule substance in the blood can freely pass through, and can not pass through than macromole (as most albumen, plasma fraction material, hemocyte etc.) in the blood.Semipermeable membrane on the general transfusion filters can pass through middle small-molecule substance, and hemodialyzer can only pass through small-molecule substance, so the scope that they remove toxin is different, general hemofiltration adopts transfusion filters when treating, and adopts hemodialyzer during hemodialysis.
Hemodialysis is to utilize disperse and ultrafiltration principle that patient's blood, dialysis solution are introduced dialyser simultaneously, both sides are reverse flow inside and outside dialyzer, solute concentration gradient, osmotic gradient and hydraulic pressure gradient by means of both sides inside and outside the film, reach the both sides concentration balance by dispersion, remove human body intracellular metabolic refuse and excessive moisture, the material that needs be can replenish simultaneously, electrolyte and acid base imbalance corrected.Hemofiltration is to utilize barometric gradient, and harmful substance in the blood and moisture are excreted by the filter semipermeable membrane, mends a certain amount of displacement liquid simultaneously and goes into blood of human body, corrects electrolyte and acid base imbalance.The respond well of micromolecule toxin generally removed in hemodialysis, and middle molecule toxins is not almost had scavenging action, and patient tolerability is poor in the therapeutic process; And hemofiltration middle molecule toxins removing effect is better, and helps the blood pressure stabilization in the patient treatment process, but micromolecule removing effect is relatively poor.
Hemodiafiltration treatment (HDF) is a kind of mode that dialysis and filtering therapy carry out simultaneously, and it combines the advantage of hemodialysis and hemofiltration.At present, the blood purification field does not still have the blood cleaning equipment that carries out the hemodiafiltration treatment simultaneously.Existing dialysis machine automaticity is not high, the operation more complicated; Use and filtering machine generally adopts artificial preparation displacement liquid or buy ready-made displacement liquid, have complex operation, easy pollution, the more high shortcoming of price.Specifically be described below:
The shortcoming and defect part that homemade haemodialysis control unit or blood filtering machine exist has:
1, nothing is carried out dialysis filtration treatment (HDF) function simultaneously, can only carry out dialysis treatment or filtering therapy separately;
2, no online (on_line) displacement liquid systematic function can only use normal saline or dialysis powder human configuration, the less and easy pollution of displacement liquid measure;
3, to reverse osmosis water without preheating device, the reverse osmosis water temperature difference that causes passing in and out heater is bigger, and the dialysate temperature fluctuation range is bigger, and the complete machine consumed power is bigger;
4, no capacity ultrafiltration mode, the dehydration error is bigger;
5, no automatic liquid matching device, automaticity is not high, and dialysis solution of allotting or displacement liquid ion concentration are inaccurate, and therapeutic process is dangerous;
6, do not have the multiple dialysis solution prescription of selection function, can not use the concentrated solution of multiple dosing ratio;
The shortcoming or the weak point of import haemodialysis control unit or blood filtering machine existence at present have:
1, nothing is carried out dialysis filtration treatment (HDF) function simultaneously, can only carry out dialysis treatment or filtering therapy separately;
2, no online (on_line) displacement liquid systematic function can only use normal saline or dialysis powder human configuration, the less and easy pollution of displacement liquid measure;
3, machine costs an arm and a leg, and causes hemodialysis or filtering therapy cost higher, increases hospital and patient's financial burden;
4, no special perfusion treatment function, the inconvenient and waste dialysis solution of perfusion treatment;
5, complex structure, operation inconvenience, easy break-down, maintenance difficult;
6, operation control display floater and LCDs are English display, and operator's English level is had relatively high expectations, and be not easy to operation and timely reaction is made in warning.
Summary of the invention
For solving above technical problem, the object of the present invention is to provide a kind ofly can dialyse simultaneously, filtering therapy, and have the medical hemodialysis filter of online displacement liquid systematic function.
Technical scheme of the present invention is as follows: a kind of medical hemodialysis filter, side at main frame is provided with side lever, by the filter folder transfusion filters is installed on the side lever, the blood inlet of this transfusion filters connects the tremulous pulse loop pipe, blood pump, heparin pump and tremulous pulse air bubble trap are housed on the tremulous pulse loop pipe, constitute the tremulous pulse loop; The blood liquid outlet of described transfusion filters connects the vein loop pipe, and venous pressure monitor, air monitor and venous air bubble trap are housed on the vein loop pipe, constitutes the vein loop; The inlet of described tremulous pulse air bubble trap or venous air bubble trap also links to each other with the fluid infusion joint by the fluid infusion loop pipe, and the fluid infusion pump is housed on the fluid infusion loop pipe, constitutes the fluid infusion loop; Front upper at main frame is provided with operation control display floater, and operation control display floater is electrically connected with monitor by the control circuit in the main frame, constitutes operation control system, and its key is:
A, the reverse osmosis water joint is housed in the bottom, side of described main frame, this reverse osmosis water joint joins by the inlet that pipeline connects behind the heater and first gear pump with depassing unit, the liquid outlet of this depassing unit connects the inlet of mixing arrangement, and the gas outlet of depassing unit links to each other with the waste liquid joint of main frame sidewall, and the bubble in the reverse osmosis water is discharged;
The positive basifacial of B, described main frame is equipped with A liquid joint and B liquid joint, inlet with described mixing arrangement behind the A liquid joint connection A concentrate pump joins, the inlet that B liquid joint connects behind the B concentrate pump also with described mixing arrangement joins, the liquid outlet of this mixing arrangement links to each other with the dialysis solution import of capacitance balance and ultrafiltration apparatus after connecting ion concentration monitor by pipeline, is input in capacitance balance and the ultrafiltration apparatus after A, B concentrated solution and reverse osmosis water are mixed;
The dialysis solution outlet of C, described capacitance balance and ultrafiltration apparatus is connected with the inlet of endotoxin filter, and the side pipe mouth of this endotoxin filter connects the fluid infusion joint, will inject venous air bubble trap or tremulous pulse air bubble trap behind the part dialysate filter.The liquid outlet of described endotoxin filter enters the mouth by the dialysis solution that pipeline connects transfusion filters, and another part dialysis solution is injected transfusion filters; The dialysis solution outlet of transfusion filters is joined with the waste liquid import of described capacitance balance and ultrafiltration apparatus after connecting the blood leakage monitor and second gear pump by pipeline, and the waste liquid outlet on this capacitance balance and the ultrafiltration apparatus is connected to the waste liquid joint, and waste liquid is discharged.
Reverse osmosis water after the present invention adopts depassing unit to heating carries out degassing processing, prevent that the bubble in dialysis solution and the displacement liquid from producing air embolism to blood, and avoid being mixed with in the dialysis solution gas and cause instability of flow, or accumulate in dialyzer one side and make dialysis-effect relatively poor, guarantee treatment fully, safety and dehydration precision height.
After two concentrate pump suction A, B concentrated solution and reverse osmosis waters are prepared by a certain percentage among the present invention, through mixing arrangement regeneration dialysis solution, and adopt the ion concentration monitoring device to monitor to the dialysis solution that generates, guarantee that the dialysis solution ion concentration is accurate, and can be suitable for different concentrated liquid prescriptions.A, B concentrated solution are two kinds of liquid that concentration is higher that are used for disposing dialysis solution, and general A concentrated solution is by NaCl, KCl, Ca 2Cl, Mg 2Solutes such as Cl and reverse osmosis water (or distilled water) are formulated, and the B concentrated solution is by NaHCO 3And reverse osmosis water (or distilled water) is made into; Two kinds of concentrated solutions of A, B configuration separately are main because of their stable components, deposit concentration in the short time and do not change substantially.
The endotoxin filter filters dialysis solution and generates aseptic apyrogenic displacement liquid among the present invention, adopts hydraulic pressure measure device monitoring endotoxin filter film external and internal pressure simultaneously, guarantees that therapeutic process safety and treatment cost are lower.
Capacitance balance and ultrafiltration apparatus have guaranteed the fluid balance of turnover hemodialyzer (or transfusion filters) and have reached the purpose of dewatering from human body among the present invention, and dehydration precision height.The mode of mending displacement liquid in the venous air bubble trap after blood flow is crossed transfusion filters is called back dilution fluid infusion; The mode of mending displacement liquid in the tremulous pulse air bubble trap before blood flow is crossed transfusion filters is called preceding dilution fluid infusion.Preceding dilution fluid infusion is with the difference of back dilution fluid infusion: the displacement liquid that preceding dilution fluid infusion is wasted is more than the back dilution, but transfusion filters is not easy blood coagulation in the therapeutic process; The displacement liquid that the back dilution is used is less, but the easy blood coagulation of transfusion filters in the therapeutic process.
On the connecting line of above-mentioned reverse osmosis water joint and heater heat exchanger is housed, promptly the reverse osmosis water joint is connected with the reverse osmosis water import of heat exchanger, and the reverse osmosis water outlet of heat exchanger links to each other with heater; The waste liquid import of described heat exchanger connects the waste liquid outlet of capacitance balance and ultrafiltration apparatus, and the waste liquid outlet of heat exchanger connects the waste liquid joint.Heat exchanger carries out The pre-heat treatment to reverse osmosis water, and then by heater heating reverse osmosis water, temperature control is steady and precision is higher.
On the connecting line of above-mentioned reverse osmosis water joint and heat exchanger pressure switch and air relief valve are housed, this pressure switch is electrically connected with control circuit, and shows the inverse seepage water pressure state by operation control display floater.Air relief valve carries out reduced pressure treatment to the reverse osmosis water that enters machine, and subject range is wider, adopts pressure switch to detect intake pressure, guarantees that machine run is safe and reliable.
On above-mentioned tremulous pulse air bubble trap the arterial blood pressure monitoring device is housed, this arterial blood pressure monitoring device is electrically connected with control circuit, and shows the arterial pressure state by operation control display floater.This arterial pressure value is used for transmembrane pressure (TMP) value of accurate Calculation hemodialyzer (or transfusion filters).Transmembrane pressure is meant the difference of transfusion filters (or dialyser) film internal pressure and film external pressure, and the computing formula that general machine is used is: transmembrane pressure=(venous pressure+arterial pressure)/2-hydraulic pressure of dialysing.When transmembrane pressure is too high, rupture of membranes phenomenon (be hollow-fiber film may by materials such as hemocytees) or blood coagulation phenomenon may appear in hemodialyzer (or filter), so the abnormal conditions alarm indicator on the control display floater in time that the present invention can transmembrane pressure occur.
On the connecting line between above-mentioned endotoxin filter liquid outlet and the transfusion filters dialysis solution inlet temperature monitoring is housed, this temperature monitoring is electrically connected with control circuit, and shows the dialysate temperature state by operation control display floater.Temperature monitoring is monitored dialysis solution and displacement liquid, guarantees patient treatment safety, and controls temperature easily.
On the connecting line between said temperature monitor and the transfusion filters dialysis solution inlet, second electromagnetic valve is housed, on the connecting line between the dialysis solution outlet of blood leakage monitor and transfusion filters the 3rd electromagnetic valve is housed, pipeline between the described temperature monitoring and second electromagnetic valve is connected between blood leakage monitor and the 3rd electromagnetic valve by bypass pipe, and first electromagnetic valve is housed on this bypass pipe.When dialysis solution entered transfusion filters, if abnormal conditions such as concentration, temperature, pressure appear in dialysis solution, machine cut out the path that enters transfusion filters rapidly, and dialysis solution flows away from bypass pipe, guaranteed treatment safety.
On the connecting line between above-mentioned the 3rd electromagnetic valve and the blood leakage monitor hydraulic pressure measure device is housed, this hydraulic pressure measure device is electrically connected with control circuit, and shows hydraulic state by operation control display floater.The hydraulic pressure measure device is monitored dialysis hydraulic pressure, and calculates the transmembrane pressure (TMP) of transfusion filters with this value.
On the connecting line of the above-mentioned blood leakage monitor and second gear pump exhaust apparatus is housed, the gas outlet, top of this exhaust apparatus is connected with the waste liquid import of heat exchanger.Exhaust apparatus can be discharged from the gas leakage of transfusion filters joint, makes easy to operately, guarantees the dehydration precision.
Above-mentioned ion concentration monitor, capacitance balance and ultrafiltration apparatus and blood leakage monitor are electrically connected with control circuit respectively, and by operation control display floater show state.
On the above-mentioned vein loop pipe that is connected venous air bubble trap liquid outlet flow plug is housed, this flow plug is electrically connected with control circuit, and by operation control display floater display abnormality state.Detention device occlude blood loop has allowed bubble or contaminated blood can not enter human body when the bubble warning occurring or leaking blood reporting to the police, and guarantees therapeutic process safety.
When the present invention uses, can on the bottom platform of main frame, place A concentrated solution bucket and B concentrated solution bucket, be inserted with the suction pipe that connects A liquid joint in the A concentrated solution bucket, be inserted with the suction pipe that connects B liquid joint in the B concentrated solution bucket.The unlatching machine can directly be inhaled A in A, B concentrated solution bucket, the B concentrated solution enters the machines configurations dialysis solution, also is fit to the concentrated solution that large hospital connects the center liquid-supplying system.
The present invention has adopted hydraulic pressure measure device, temperature monitoring, ion concentration monitoring device, blood leakage monitor etc. in the water circuit system that parts such as reverse osmosis water joint, heater, depassing unit, A concentrate pump, B concentrate pump, mixing arrangement, capacitance balance and ultrafiltration apparatus and endotoxin filter are formed; Arterial blood pressure monitoring device and heparin pump on the tremulous pulse loop pipe, have been adopted, venous pressure monitor, air monitor, flow plug on the vein loop pipe, have been adopted, fully guarantee the security monitoring and the automatic function of therapeutic process, thereby improved the security reliability and the automaticity of hemodiafiltration therapeutic process.
The present invention can adopt Chinese operation control display floater to realize the human computer conversation, does not need to ask operator's English level, and is more convenient to operate and can make reaction fast and accurately to alarm; The panel of Chinese operation has perfect monitoring key switch, can conveniently realize safety monitoring and the real-time monitoring of enforcement to the entire machine operation.
The present invention does not connect the fluid infusion loop if adopt the small throughput dialyser, can make hemodialysis; If adopt high flux hemodialyzer (or transfusion filters), the fluid infusion loop pipe is connected fluid infusion joint, fluid infusion pump and venous air bubble trap (or tremulous pulse air bubble trap), can do the treatment of hemodiafiltration or hemofiltration; If change hemodialyzer into blood perfusion device, can also do the hemoperfusion treatment, realize a tractor serves several purposes.
The invention has the beneficial effects as follows:
1, can carry out hemodialysis, filtering therapy simultaneously, combine the advantage of dialysis and filtering therapy, the removing effect of centering small-molecule substance is all good, blood pressure stabilization in the patient treatment process;
2, the aseptic apyrogenic displacement liquid of the online generation of energy, and overall process has the watch-dog monitoring, and treatment is convenient, safety;
3, can carry out hemodialysis separately, fully remove intravital small-molecule substance of patient and redundant moisture;
4, can carry out the hemofiltration treatment separately, can effectively remove intravital medium molecular substance of patient and excessive moisture, blood pressure stabilization in the patient treatment process has certain scavenging action to small-molecule substance;
5, be provided with hemoperfusion treatment pattern specially, easy to operate quick, do not waste dialysis solution;
6, machine intimate is equipped with back-up source, even still can continue to treat 15 minutes under situation about having a power failure suddenly, is convenient to medical personnel's in-situ processing;
7, the complete machine monitoring function is comprehensive, reliable, automaticity height, therapeutic process safety, operability height;
8, adopt the flow quantity and the dehydration of capacitance balance and ultrafiltration apparatus control turnover transfusion filters, the dehydration precision reaches 10ml/h;
9, operation control display floater and LCDs be the Chinese demonstration, and it is easy to operate and warning made timely reaction to be convenient to operator.
Description of drawings
Fig. 1 is a front view of the present invention.
Fig. 2 is a cut-away view of the present invention.
The specific embodiment
The invention will be further described below in conjunction with drawings and Examples:
As shown in Figure 1 and Figure 2, the present invention is made up of body, blood circuit, fluid infusion loop, water circuit system and operation control system.Body comprises main frame 1, side lever 2 and filter folder 7, and side lever 2 is arranged on main frame 1 left side, and by filter folder 7 transfusion filters 6 is installed.Blood circuit comprises tremulous pulse loop and vein loop, and the blood inlet of described transfusion filters 6 connects tremulous pulse loop pipe 9, and blood pump 8, heparin pump 22, tremulous pulse air bubble trap 4 and arterial blood pressure monitoring device 3 are housed on tremulous pulse loop pipe 9, constitutes the tremulous pulse loop; The blood liquid outlet of transfusion filters 6 connects vein loop pipe 5, and venous pressure monitor 15, air monitor 16, venous air bubble trap 17 and flow plug 18 are housed on vein loop pipe 5, constitutes the vein loop; The inlet of described venous air bubble trap 17 also links to each other with fluid infusion joint 20 on main frame 1 right sidewall by fluid infusion loop pipe 21, and fluid infusion pump 19 is housed on fluid infusion loop pipe 21, constitutes the fluid infusion loop.
Water circuit system of the present invention comprises parts compositions such as reverse osmosis water joint 32, heat exchanger 36, heater 31, first gear pump 42, depassing unit 39, A concentrate pump 37, B concentrate pump 38, mixing arrangement 40, ion concentration monitor 41, capacitance balance and ultrafiltration apparatus 28 and endotoxin filter 29.Right flank bottom at main frame 1 is provided with reverse osmosis water joint 32, this reverse osmosis water joint 32 is by the suitable reverse osmosis water import that connects pressure switch 33, air relief valve 35 and heat exchanger 36 of pipeline, the reverse osmosis water outlet of heat exchanger 36 is connected with heater 31, the waste liquid import of described heat exchanger 36 connects the waste liquid outlet of capacitance balance and ultrafiltration apparatus 28, and the waste liquid outlet of heat exchanger 36 connects the waste liquid joint 34 of reverse osmosis water joint 32 belows.Heater 31 is along the inlet that connects first gear pump 42 and depassing unit 39, and the liquid outlet of this depassing unit 39 connects the inlet of mixing arrangement 40, and the gas outlet of depassing unit 39 links to each other with the waste liquid import of heat exchanger 36, and the bubble in the reverse osmosis water is discharged.
Positive basifacial at main frame 1 is equipped with A liquid joint 23 and B liquid joint 24, the inlet that A liquid joint 23 connects A concentrate pump 37 backs and described mixing arrangement 40 joins, the inlet that B liquid joint 24 connects behind the B concentrate pumps 38 also with described mixing arrangement 40 joins, the liquid outlet of this mixing arrangement 40 connects ion concentration monitor 41 backs by pipeline and links to each other with the dialysis solution import of capacitance balance and ultrafiltration apparatus 28, and the dialysis solution that A, B concentrated solution and reverse osmosis water is mixed the back generation is input in capacitance balance and the ultrafiltration apparatus 28.The dialysis solution outlet of described capacitance balance and ultrafiltration apparatus 28 is connected with the inlet of endotoxin filter 29, and the side pipe mouth of this endotoxin filter 29 connects fluid infusion joint 20, will inject venous air bubble trap 17 behind the part dialysate filter.The liquid outlet of endotoxin filter 29 along the dialysis solution inlet that connects temperature monitoring 27, second electromagnetic valve 26, dialysis solution joint 10 and transfusion filters 6, injects transfusion filters 6 with another part dialysis solution by pipeline; The dialysis solution outlet of transfusion filters 6 is by the suitable inlet that connects waste liquid joint 11, the 3rd electromagnetic valve 47, hydraulic pressure measure device 46, blood leakage monitor 45 and exhaust apparatus 44 of pipeline.Pipeline between the described temperature monitoring 27 and second electromagnetic valve 26 is connected between blood leakage monitor 45 and the hydraulic pressure measure device 46 by bypass pipe, and first electromagnetic valve 25 is housed on this bypass pipe.
The gas outlet, top of described exhaust apparatus 44 is connected with the waste liquid import of heat exchanger 36, the liquid outlet of described exhaust apparatus 44 joins along the waste liquid import that connects second gear pump 43 and capacitance balance and ultrafiltration apparatus 28 by pipeline, and the waste liquid outlet of this capacitance balance and ultrafiltration apparatus 28 is connected to the waste liquid import of heat exchanger 36.
Front upper at main frame 1 is provided with operation control display floater 14, operation control display floater 14 is electrically connected with pressure switch 33, flow plug 18 and all monitors by the control circuit 48 in the main frame 1, and the liquid crystal display of controlling on the display floater 14 by operation carries out the state demonstration, the formation operation control system.On operation control display floater 14, be distributed with and each monitor corresponding key switch, can conveniently realize safety monitoring and the real-time monitoring of enforcement the entire machine operation.
Work process of the present invention is as follows:
As shown in Figure 1 and Figure 2, on the bottom platform of main frame 1, place A concentrated solution bucket 13 and B concentrated solution bucket 12, be inserted with the suction pipe that connects A liquid joint 23 in the A concentrated solution bucket 13, be inserted with the suction pipe that connects B liquid joint 24 in the B concentrated solution bucket 12.Reverse osmosis water enters machine reverse osmosis water joint 32, whether pressure switch 33 monitoring pressures reach setting value, again through entering heat exchanger 36 preheatings after air relief valve 35 decompressions, after reverse osmosis water after the preheating enters heater 31 heating, first gear pump 47 is therefrom extracted the bubble that is melted in a large number in the water out, enter depassing unit 39, air is discharged to the waste liquid end of heat exchanger 36 from the top, and the reverse osmosis water of process degasification flows out from the bottom of depassing unit 39.Through heating, reverse osmosis water after the aerofluxus again with A concentrate pump 37, after mixing, the concentrated solution that B concentrate pump 38 sucks enters ion concentration monitor 40 in mixing arrangement 40, control circuit 48 is adjusted A according to monitor value, B concentrate pump rotating speed, reach setting value up to ion concentration, the dialysis solution that generates enters capacitance balance and ultrafiltration apparatus 28, come out to enter endotoxin filter 29, a part is carried out mass exchange by directly entering in the film of endotoxin filter 29 in the transfusion filters 6 with blood, and another part filters the back by entering blood of human body in the fluid infusion pump 19 afferent veins air bubble traps 17 (or tremulous pulse air bubble trap 4) through endotoxin filter 29.The waste liquid that comes out from transfusion filters 6 is through hydraulic pressure measure device 46 and leak its rupture of membranes whether of blood pick off 45 monitorings, enter exhaust apparatus 44 then from the top aerofluxus, after pumping into capacitance balance and ultrafiltration apparatus 28 by second gear pump 43, waste liquid in the exhaust apparatus 44 is discharged to heat exchanger 36, the waste liquid amount of discharging from capacitance balance and ultrafiltration apparatus 28 is dehydrating amount from human body more than the dialysis liquid measure that enters, and last waste liquid is discharged machine behind over-heat-exchanger 36 preheating reverse osmosis waters.
Blood samples of patients relies on outside blood pump 8 lead bodies, enter the transfusion filters 6 of blood circuit, through failing the Huis' vena systemica through venous air bubble trap 17, flow plug 18 backs again after purifying, the pump 19 of fluid infusion simultaneously pumps displacement liquid from fluid infusion joint 20 and injects venous air bubble trap 17, heparin pump 22 continues to inject heparin and prevent transfusion filters 6 blood coagulations in tremulous pulse loop pipe 9, and this process medium-sized artery presses security monitoring blood such as monitor 3, venous pressure monitor 15, air monitor 16 to enter human body.
In the whole therapeutic process, monitoring system is by force value, the bubble situation in moment monitoring of blood loop, monitoring water circuit system liquid pressure value, temperature value, ion concentration value, bubble situation etc.,, temperature value unusual as the dialysis solution ion concentration is unusual, when transmembrane pressure and leakage blood are reported to the police, first electromagnetic valve 25 in the water route is opened, second electromagnetic valve 26, the 3rd electromagnetic valve 47 closures, from transfusion filters 6 bypass dialysis solution, dialysis solution no longer enters transfusion filters, displacement liquid stops to mend blood, the fluid infusion pump shuts down, and guarantees treatment safety.

Claims (10)

1, a kind of medical hemodialysis filter, side at main frame (1) is provided with side lever (2), side lever (2) is gone up by filter folder (7) transfusion filters (6) is installed, the blood inlet of this transfusion filters (6) connects tremulous pulse loop pipe (9), blood pump (8), heparin pump (22) and tremulous pulse air bubble trap (4) are housed on tremulous pulse loop pipe (9), constitute the tremulous pulse loop; The blood liquid outlet of described transfusion filters (6) connects vein loop pipe (5), and venous pressure monitor (15), air monitor (16) and venous air bubble trap (17) are housed on vein loop pipe (5), constitutes the vein loop; The inlet of described tremulous pulse air bubble trap (4) or venous air bubble trap (17) also links to each other with fluid infusion joint (20) by fluid infusion loop pipe (21), and fluid infusion pump (19) is housed on fluid infusion loop pipe (21), constitutes the fluid infusion loop; Front upper at main frame (1) is provided with operation control display floater (14), and operation control display floater (14) is electrically connected with monitor by the control circuit (48) in the main frame (1), constitutes operation control system, it is characterized in that:
A, reverse osmosis water joint (32) is housed in the bottom of described main frame (1), this reverse osmosis water joint (32) joins by the inlet that pipeline connects heater (31) and first gear pump (42) back and depassing unit (39), the liquid outlet of this depassing unit (39) connects the inlet of mixing arrangement (40), and the gas outlet of depassing unit (39) links to each other with the waste liquid joint (34) of main frame (1) sidewall, and the bubble in the reverse osmosis water is discharged;
The positive basifacial of B, described main frame (1) is equipped with A liquid joint (23) and B liquid joint (24), the inlet that A liquid joint (23) connects A concentrate pump (37) back and described mixing arrangement (40) joins, the inlet that B liquid joint (24) connects behind the B concentrate pump (38) also with described mixing arrangement (40) joins, the liquid outlet of this mixing arrangement (40) connects ion concentration monitor (41) back by pipeline and links to each other with the dialysis solution import of capacitance balance and ultrafiltration apparatus (28), is input in capacitance balance and the ultrafiltration apparatus (28) after A, B concentrated solution and reverse osmosis water are mixed;
The dialysis solution outlet of C, described capacitance balance and ultrafiltration apparatus (28) is connected with the inlet of endotoxin filter (29), the side pipe mouth of this endotoxin filter (29) connects fluid infusion joint (20), will inject tremulous pulse air bubble trap (4) or venous air bubble trap (17) behind the part dialysate filter; The liquid outlet of described endotoxin filter (29) enters the mouth by the dialysis solution that pipeline connects transfusion filters (6), and another part dialysis solution is injected transfusion filters (6); The dialysis solution outlet of transfusion filters (6) connects blood leakage monitor (45) by pipeline and second gear pump (43) back joins with the waste liquid import of described capacitance balance and ultrafiltration apparatus (28), waste liquid outlet on this capacitance balance and the ultrafiltration apparatus (28) is connected to waste liquid joint (34), and waste liquid is discharged.
2, hemodialysis filter according to claim 1, it is characterized in that: on the connecting line of described reverse osmosis water joint (32) and heater (31), heat exchanger (36) is housed, be that reverse osmosis water joint (32) is connected with the reverse osmosis water import of heat exchanger (36), the reverse osmosis water outlet of heat exchanger (36) links to each other with heater (31); The waste liquid import of described heat exchanger (36) connects the waste liquid outlet of capacitance balance and ultrafiltration apparatus (28), and the waste liquid outlet of heat exchanger (36) connects waste liquid joint (34).
3, hemodialysis filter according to claim 2, it is characterized in that: on the connecting line of described reverse osmosis water joint (32) and heat exchanger (36), pressure switch (33) and air relief valve (35) are housed, this pressure switch (33) is electrically connected with control circuit (48), and shows the inverse seepage water pressure state by operation control display floater (14).
4, hemodialysis filter according to claim 1, it is characterized in that: arterial blood pressure monitoring device (3) is housed on described tremulous pulse air bubble trap (4), this arterial blood pressure monitoring device (3) is electrically connected with described control circuit (48), and shows the arterial pressure state by operation control display floater (14).
5, hemodialysis filter according to claim 1, it is characterized in that: on the connecting line between described endotoxin filter (29) liquid outlet and transfusion filters (6) the dialysis solution inlet, temperature monitoring (27) is housed, this temperature monitoring (27) is electrically connected with described control circuit (48), and shows the dialysate temperature state by operation control display floater (14).
6, hemodialysis filter according to claim 5, it is characterized in that: on the connecting line between described temperature monitoring (27) and transfusion filters (6) the dialysis solution inlet, second electromagnetic valve (26) is housed, on the connecting line between described blood leakage monitor (45) and the outlet of transfusion filters (6) dialysis solution the 3rd electromagnetic valve (47) is housed, pipeline between described temperature monitoring (27) and second electromagnetic valve (26) is connected between described blood leakage monitor (45) and the 3rd electromagnetic valve (47) by bypass pipe, and first electromagnetic valve (25) is housed on this bypass pipe.
7, hemodialysis filter according to claim 6, it is characterized in that: on the connecting line between described the 3rd electromagnetic valve (47) and the blood leakage monitor (45), hydraulic pressure measure device (46) is housed, this hydraulic pressure measure device (46) is electrically connected with described control circuit (48), and shows hydraulic state by operation control display floater (14).
8, according to claim 2 or 3 described hemodialysis filters, it is characterized in that: on the connecting line of described blood leakage monitor (45) and second gear pump (43) exhaust apparatus (44) is housed, the gas outlet, top of this exhaust apparatus (44) is connected with the waste liquid import of described heat exchanger (36).
9, hemodialysis filter according to claim 1, it is characterized in that: described ion concentration monitor (41), capacitance balance and ultrafiltration apparatus (28) and blood leakage monitor (45) are electrically connected with described control circuit (48) respectively, and by operation control display floater (14) show state.
10, hemodialysis filter according to claim 1, it is characterized in that: be connected on the vein loop pipe (5) of venous air bubble trap (17) liquid outlet flow plug (18) is housed, this flow plug (18) is electrically connected with described control circuit (48), and by operation control display floater (14) display abnormality state.
CNB2006100542091A 2006-04-12 2006-04-12 Medical hemodialysis filter Active CN100460026C (en)

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CN100460026C CN100460026C (en) 2009-02-11

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Cited By (29)

* Cited by examiner, † Cited by third party
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CN101829371A (en) * 2010-05-20 2010-09-15 重庆山外山科技有限公司 Hemodialysis system
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