CN1582754A - Nutrient food for increasing immunity and relaking fatigue - Google Patents

Nutrient food for increasing immunity and relaking fatigue Download PDF

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Publication number
CN1582754A
CN1582754A CNA2004100460302A CN200410046030A CN1582754A CN 1582754 A CN1582754 A CN 1582754A CN A2004100460302 A CNA2004100460302 A CN A2004100460302A CN 200410046030 A CN200410046030 A CN 200410046030A CN 1582754 A CN1582754 A CN 1582754A
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China
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powder
trehalose
nutraceutical
human body
ethanol
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CNA2004100460302A
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Chinese (zh)
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申琳
生吉萍
姜立新
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China Agricultural University
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China Agricultural University
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Abstract

A nutritive food in the form of instant particle, effervescent tablet, or capsules for improving immunity and relieving fatigue is prepared from ant extract, fleece flower root, ganoderma, grape seed extract (OPC), mycose, lipid, dextrin and starch.

Description

Nutraceutical of enhancing human body immunity power and fatigue alleviating and preparation method thereof
Technical field
The invention belongs to food-processing method, relate to specifically have certain health care functions, edible a kind of enhancing human body immunity power easy to carry and nutraceutical of fatigue alleviating and preparation method thereof.
Background technology
Raising along with modern society's economic life level, people no longer satisfy generally " having ample food and clothing " of pursuit of material institute in deficient period already, then turn one's attention to the auxiliary health food of some high-quality, high nutrition, thereby increase the ability of resisting disease, strong physique, improve the quality of living, and prolong the existence time limit as much as possible, be a long-lived person.Nutritional health food is a lot of on the market, but most of composition is relatively more dull, health care is single.Present employing raw material is that the nutritional health food of multiple components combinations such as the smart powder of ant, Radix Polygoni Multiflori, Ganoderma, Semen Vitis viniferae extract (OPC), dextrin, trehalose, starch is also rare.
Summary of the invention
The purpose of this invention is to provide a kind of have certain health care functions, edible enhancing human body immunity power easy to carry and nutraceutical of fatigue alleviating and preparation method thereof.It is characterized in that: described enhancing human body immunity power and fatigue alleviating nutraceutical are to use for reference the Chinese materia medica compatibility of drugs and the principles of formulating prescriptions, with smart powder: the 10-45% of the ant of counting by weight percentage; Radix Polygoni Multiflori: 10-55%; Ganoderma powder: 5-40% and OPC:0.1-15% combine, and add protective agent simultaneously: 0.1-5% trehalose, liposome and powder-beta-dextrin; Adjuvant: 1-11% starch is made graininess electuary, effervescent tablet or is poured into hard capsule.
The refining nutraceutical of described enhancing human body immunity power, slow down aging and fatigue alleviating, realize by following steps:
(1) Formica fusca is used flushing with clean water, stirring, press the ethanol percolation of percolation with 60% percentage by weight, collect filtrate just, subsequent filtrate is used as next diafiltration.Just filtrate adds the low sugariness non-reducible disaccharide of 0.1-5%, and mixing, decompression recycling ethanol be to the thick paste shape, pour into to fill in the rebasing pallet of starch, oven dry, pulverizing is crossed 100 mesh sieves, the smart powder of ant.
(2) Radix Polygoni Multiflori, Ganoderma are placed extraction pot, water for degree, did not soak 3 hours.Carry out conventional hot water extraction then 3 times: 2 hours for the first time, 1.5 hours for the second time, 0.5 hour for the third time, merge three extracting solution and concentrate, add the low sugariness non-reducible disaccharide of 0.1-5%, add 95% ethanol again and carry out precipitate with ethanol; At the clear paste of 60-65 ℃ of following reduced-pressure backflow ethanol to relative density 1.35-1.38, add starch at last, oven dry is pulverized, and crosses 100 mesh sieves and obtains extract powder.
(3) product and the OPC fine powder that step (1) (2) is obtained or adopt commercially available finished product, its procyanidin content is sent into blender by formula proportion and was mixed 15 minutes greater than 95% OPC.
(4) product that step (1), (2), (3) is obtained adds 1-11% starch or sucrose again with after hanging down sugariness irreducibility trehalose, liposome and powder-beta-dextrin embedding, can be made into graininess electuary or effervescent tablet, cobalt-608KGY irradiation sterilization; Or the product that step (3) is obtained pours in the hard capsule cobalt-60 8KGY irradiation sterilization with after a small amount of low sugariness irreducibility trehalose mixes by every 400mg loading amount.
Beneficial effect of the present invention is; use for reference the Chinese materia medica compatibility of drugs and the principles of formulating prescriptions; the smart powder of ant, Radix Polygoni Multiflori, Ganoderma and Semen Vitis viniferae extract are combined; carry out nutrition protection with low sugariness irreducibility trehalose and liposome simultaneously, make abundanter, more reasonable, the preferably absorption of human body utilization of its compositions nutrition.Though the smart powder nutrition of ant is extremely abundant, slightly little poison; The Radix Polygoni Multiflori function is remarkable, and has the function of detoxifcation; The Ganoderma effect is more extensive, and the effect of toxin expelling is arranged; Semen Vitis viniferae extract has the free radical of removing, improves nutrient bioavailability function, just can detect its existence in oral 20 minutes in blood, makes the effect of its performance " tying-in ", fast the nutrient substance in this compositions is caused organ required in the body; Low sugariness irreducibility trehalose and liposome have the function that the protection nutrient is avoided losing.So be " monarch drug " with the smart powder of ant in the combination, with Radix Polygoni Multiflori is " ministerial drug ", with Ganoderma is " adjuvant drug ", with Semen Vitis viniferae extract is " messenger drug ", with irreducibility trehalose and liposome is " protecting medicine ", thereby the product that makes this invention manufacture has science, practicality, creativeness, the feature of outstanding oriental food.
The specific embodiment
The present invention is a kind of have certain health care functions, edible enhancing human body immunity power easy to carry and fatigue alleviating nutraceutical and preparation method thereof.The nutraceutical of this enhancing human body immunity power and fatigue alleviating is to use for reference the Chinese materia medica compatibility of drugs and the principles of formulating prescriptions, with smart powder: the 10-45% of the ant of counting by weight percentage; Radix Polygoni Multiflori: 10-55%; Ganoderma powder: 5-40% and Semen Vitis viniferae extract: 0.1-15% combines, and adds protective agent simultaneously: 0.1-5% trehalose, liposome and powder-beta-dextrin; Adjuvant: 1-11% starch is made graininess electuary, effervescent tablet or is poured into hard capsule.
The refining nutraceutical of described enhancing human body immunity power, slow down aging and fatigue alleviating, realize by following steps:
(1) Formica fusca is used flushing with clean water, stirring, press percolation 60% ethanol percolation, collect filtrate just, subsequent filtrate is used as next diafiltration.Just filtrate adds the low sugariness irreducibility trehalose of 0.1-5%, and mixing, decompression recycling ethanol be to the thick paste shape, pour into to fill in the rebasing pallet of starch, oven dry, pulverizing is crossed 100 mesh sieves, the smart powder of ant.
(2) Radix Polygoni Multiflori, Ganoderma are placed extraction pot, water for degree, did not soak 3 hours.Carry out conventional hot water extraction then 3 times: 2 hours for the first time, 1.5 hours for the second time, 0.5 hour for the third time, merge three extracting solution and concentrate, add a small amount of low sugariness irreducibility trehalose, add 95% ethanol again and carry out precipitate with ethanol; At the clear paste of 60-65 ℃ of following reduced-pressure backflow ethanol to relative density 1.35-1.38, add starch at last, oven dry is pulverized, and crosses 100 mesh sieves and obtains extract powder.
(3) product and the OPC fine powder that step (1) (2) is obtained or adopt commercially available finished product, its procyanidin content is sent into blender by formula proportion and was mixed 15 minutes greater than 95% OPC.
(4) product that step (1), (2), (3) is obtained adds an amount of sucrose, starch again with after hanging down sugariness irreducibility trehalose, liposome and powder-beta-dextrin embedding, can be made into graininess electuary or effervescent tablet, cobalt-608KGY irradiation sterilization; Or the product that step (3) is obtained pours in the hard capsule cobalt-60 8KGY irradiation sterilization with after the low sugariness irreducibility trehalose of 0.1-5% mixes by every 400mg loading amount.
Described nutrient protective agent trehalose, liposome and powder-beta-dextrin are by mixed in equal amounts.
The following optimization formula of lifting and does not limit protection scope of the present invention only in order to explanation the present invention.
Example one: the smart powder of ant: 10%; Radix Polygoni Multiflori: 30%; Ganoderma powder: 35%; OPC:10%; Nutrient protective agent: 1%; Adjuvant: 4%.
Example two: the smart powder of ant: 40%; Radix Polygoni Multiflori: 10%; Ganoderma powder: 40%; OPC:5%; Nutrient protective agent: 1%; Adjuvant: 4%.
Example three: the smart powder of ant: 19%; Radix Polygoni Multiflori: 20%; Ganoderma powder: 50%; OPC:10%; Nutrient protective agent: 1%; Adjuvant: 10%.
Example four: the smart powder of ant: 50%; Radix Polygoni Multiflori: 40%; Ganoderma powder: 5%; OPC:1%; Nutrient protective agent: 0.2%; Adjuvant: 3.8%.
Example five: the smart powder of ant: 25%; Radix Polygoni Multiflori: 40%; Ganoderma powder: 31.8%; OPC:0.1%; Nutrient protective agent: 0.1%; Adjuvant: 3%.
In the above-mentioned prescription:
The smart powder of ant derives from the dry all of Hymenoptera ant insect Formica fusca and red woods ant etc., and nutritive value is high, is example with the Formica fusca, and it all contains 27 seed amino acids, and contains various trace elements, fatty acid and vitamin.Pharmacological evaluation proves that Formica fusca has the human body immunity improving function.The thymic hyperplasia that the Formica fusca aqueous extract can make aged mouse be tending towards degenerating, increased functionality, leukocyte count, macrophage function and blood serum special antibody horizontal significantly improve; Can obviously prolong the swimming time of mice, have the obvious anti-fatigue effect; The Formica fusca water decoction can recover the yang deficiency immune function of mice.Formica fusca powder can obviously prolong life span of drosophila melanogaster, and the flight number of times of aged fruit bat is increased.Ant preparation can significantly promote the recovery of old rats spermatogenic cell ability, promotes the functional activity of Interstitial cell.
Radix Polygoni Multiflori is tuber and the rattan of polygonum multiflorum thunb (Polygonnum mutiflorum Thunb.).On Chinese medicine was learned, Radix Polygoni Multiflori was warm in nature, bitter in the mouth, sweet, puckery, returns liver, the heart, kidney channel.Clinically, be used for the treatment of essence and blood and lose void, dizziness and blurred vision, soreness of the waist and knees, numb limbs and tense tendons, early whitening of beard and hair, alopecia, insomnia, hyperlipemia etc.Pharmacological evaluation proves that Radix Polygoni Multiflori has the function of enhancing immunity.Radix Polygoni Multiflori can make mouse thymus weight increase, and can also resist the atrophy of thymus gland that is caused by prednisone; Radix Polygoni Multiflori lixiviate cream can increase senile rat thymus plasmosin and nucleic acid content, improves old body thymus dependent immunologic function; Radix Polygoni Multiflori can improve the phagocytic function of Turnover of Mouse Peritoneal Macrophages.Radix Polygoni Multiflori also has anti-aging effects.Radix Polygoni Multiflori water extract can obviously suppress old mouse MAO-B activity, and enhance SOD activity promotes albumen synthetic, plays function in delaying senility; Radix Polygoni Multiflori can also reduce the lipid peroxide content in the mice plasma.
China's medical science works Shennong's Herbal record the earliest, Ganoderma can " the beneficial motive, the wisdom that increases, beneficial vital essence, hard muscles and bones, good color, for a long time clothes make light of one's life by commiting suicide, old, prolong life ".Modern pharmacological research proves, Ganoderma is except containing polysaccharide, polypeptide, several amino acids, also have ergosterol, mannitol, adenine, ribosidoadenine, uracil, uridine, 15 kinds of mineral elements such as betanin, trehalose, stearic acid, triterpenoid compound, cellulose C, vitamin B1, B2, B6, vitamin E and organic germanium.The Ganoderma water extract has SOD activity improving, increases flowability of cell membranes and sealing degree, strengthens the deformability of cell, eliminates interior free yl, reduces hematoblastic gathering performance, promotes cell DNA, RNA and protein synthesis, improves body's immunological function.
So in combinations thereof, be " monarch drug " with the smart powder of ant, with Radix Polygoni Multiflori is " ministerial drug ", with Ganoderma is " adjuvant drug ", with OPC is " messenger drug ", with irreducibility trehalose and liposome is " protecting medicine ", thereby the product that makes this invention manufacture has science, practicality, creativeness, the feature of outstanding oriental food.

Claims (3)

1. the nutraceutical of enhancing human body immunity power and fatigue alleviating, it is characterized in that: described enhancing human body immunity power and fatigue alleviating nutraceutical are to use for reference the Chinese materia medica compatibility of drugs and the principles of formulating prescriptions, with smart powder: the 10-45% of the ant of counting by weight percentage; Radix Polygoni Multiflori: 10-55%; Ganoderma powder: 5-40% and OPC:0.1-15% combine, and add protective agent simultaneously: 0.1-5% trehalose, liposome and powder-beta-dextrin; Adjuvant: 1-11% starch is made graininess electuary, effervescent tablet or is poured into hard capsule.
2. the manufacture method of the nutraceutical of enhancing human body immunity power and fatigue alleviating, it is characterized in that: the refining nutraceutical of described enhancing human body immunity power, slow down aging and fatigue alleviating is to realize by following steps:
(1) Formica fusca is used flushing with clean water, stirring, press percolation 60% ethanol percolation, collect filtrate just, subsequent filtrate is used as next diafiltration; Just filtrate adds the low sugariness irreducibility trehalose of 0.1-5%, and mixing, decompression recycling ethanol be to the thick paste shape, pour into to fill in the rebasing pallet of starch, oven dry, pulverizing is crossed 100 mesh sieves, the smart powder of ant;
(2) Radix Polygoni Multiflori, Ganoderma are placed extraction pot, water is not degree, soaked 3 hours, carry out conventional hot water extraction then 3 times: 2 hours for the first time, 1.5 hours for the second time, 0.5 hour for the third time, merge three extracting solution and concentrate, add the low sugariness irreducibility trehalose of 0.1-5%, add 95% ethanol again and carry out precipitate with ethanol; Reduced-pressure backflow ethanol adds starch at last to the clear paste of relative density 1.35-1.38 (60-65 ℃), and oven dry is pulverized, and crosses 100 mesh sieves and obtains extract powder;
(3) product and the OPC fine powder that step (1) (2) is obtained or adopt commercially available finished product, its procyanidin content is sent into blender by formula proportion and was mixed 15 minutes greater than 95% OPC;
(4) after the product that step (1), (2), (3) are obtained hangs down sugariness irreducibility trehalose, liposome and powder-beta-dextrin embedding with 0.1-5%, add 1-11% starch or sucrose again, can be made into graininess electuary or effervescent tablet, cobalt-60 8KGY irradiation sterilization; Or the product that step (3) is obtained pours in the hard capsule cobalt-60 8KGY irradiation sterilization with after the low sugariness irreducibility trehalose of 0.1-5% mixes by every 400mg loading amount.
3. according to the manufacture method of the nutraceutical of described enhancing human body immunity power of claim 2 and fatigue alleviating, it is characterized in that: described nutrient protective agent trehalose, liposome and powder-beta-dextrin are by mixed in equal amounts.
CNA2004100460302A 2004-06-02 2004-06-02 Nutrient food for increasing immunity and relaking fatigue Pending CN1582754A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006023814A3 (en) * 2004-08-19 2006-10-12 Amerilab Technologies Inc Effervescent composition including a grape-derived component

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006023814A3 (en) * 2004-08-19 2006-10-12 Amerilab Technologies Inc Effervescent composition including a grape-derived component

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Open date: 20050223