CN1552397A - Shanxiangyuan drops and their preparation - Google Patents
Shanxiangyuan drops and their preparation Download PDFInfo
- Publication number
- CN1552397A CN1552397A CNA031292070A CN03129207A CN1552397A CN 1552397 A CN1552397 A CN 1552397A CN A031292070 A CNA031292070 A CN A031292070A CN 03129207 A CN03129207 A CN 03129207A CN 1552397 A CN1552397 A CN 1552397A
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- CN
- China
- Prior art keywords
- roxb
- turpinia pomifera
- leaf
- extract powder
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Medicines Containing Plant Substances (AREA)
Abstract
A dropping pill of cordyalis esquirolii for treating pharyngolaryngitis and tonsillitis is prepared from the powdered extract of corydalis esquirolii's leaf and the matrix chosen from stearic acid, gelatin, polyethanediol '6000' and poloxamer '188' through proportional mixing, heating for fusing, stirring and dropping in coolant. Its advantage is high curative effect.
Description
Technical field: the present invention relates to a kind of Turpinia pomifera(Roxb) D O. drop pill and preparation technology thereof.
Background technology: leaf of Turpinia pomifera (Roxb) D O. nature and flavor bitter cold, reach on its light weight is floating, the effect of wind and heat dispersing, resolving toxin and disinhibiting the throat is arranged, can subside a swelling by blood circulation promoting and blood stasis dispelling again, to eliminate because of wind-heat evil toxin and stop up the stagnation of QI-blood that throat causes, smooth, the swollen numbness of passages through which vital energy circulates is unfavorable.Diseases such as acute pharyngitis due to wind-heat, acute tonsillitis caused by pathogenic windheat all there is better curative effect.Suitable wind and heat dispersing, reducing swelling and alleviating pain, clearing throat.The medicament that record is made with Turpinia pomifera(Roxb) D O. on the document has at present: Hyptis suavedens round chewing gum (seeing that application number is 94112151.8) and turpinia pomifera capsule (seeing application number 95107259.6), these two kinds of medicaments that technology is made are because prescription and the rigorous inadequately pharmaceutical properties that causes of technology can not be not fully exerted.
Summary of the invention: purpose of the present invention just provides better Turpinia pomifera(Roxb) D O. drop pill of a kind of drug effect and preparation technology thereof.
Described Turpinia pomifera(Roxb) D O. drop pill is by leaf of Turpinia pomifera (Roxb) D O. extract powder and substrate, and by weight than being 1: the ratio of 1-12 is formulated.
Described leaf of Turpinia pomifera (Roxb) D O. extract powder is to be formed by following prepared: get the water that leaf of Turpinia pomifera (Roxb) D O. is put into 8 times of its weight, decoct twice, each 1-2 hour, filter, filtrate is concentrated into the extractum shape, put coldly, add ethanol and make and contain alcohol amount and reach 50-80%, leave standstill, the leaching supernatant, reclaim ethanol, crushed after being dried or spray drying promptly make the leaf of Turpinia pomifera (Roxb) D O. extract powder.
Described substrate can be stearic acid, gelatin, polyethylene glycol 6000, poloxamer 188 any materials, also can be several or whole mixture between them.
The preparation technology of described Turpinia pomifera(Roxb) D O. drop pill is as follows:
With substrate be heated to 80-100 ℃ treat whole fusions after, add the leaf of Turpinia pomifera (Roxb) D O. extract powder again, be stirred to fusion, transfer in the drilling pill device and remain on 60-100 ℃ temperature, splash in 5-20 ℃ of liquid Paraffin, vegetable oil, methyl-silicone oil, the arbitrary coolant of water, drain promptly.The preferential weight part ratio of leaf of Turpinia pomifera (Roxb) D O. extract powder recited above and substrate is: 1: 2-6 leaf of Turpinia pomifera (Roxb) D O. extract powder recited above is 1: 4 with optimum weight part ratio of substrate
The Turpinia pomifera(Roxb) D O. drop pill of the present invention's preparation has better curative effect to diseases such as treatment pharyngolaryngitis, tonsillitiss.
Embodiment 1: the substrate polyethylene glycol 6000 is heated to 80-100 ℃, after treating whole fusions, in substrate and leaf of Turpinia pomifera (Roxb) D O. extract powder weight part ratio is 2: 1 ratio, adds the leaf of Turpinia pomifera (Roxb) D O. extract powder, stirs to dissolving, and remain under 60-100 ℃ the temperature, by in drilling pill device with 30-80 drip/minute speed, splashing into temperature is in the 5-20 ℃ of methyl-silicone oil coolant, takes out drop pill, absorb condensed fluid, drying.
Embodiment 2: with polyethylene glycol 6000 and poloxamer 188, than being 6-12: 1-5, the substrate that is mixed and made into is heated to 80-100 ℃ by weight, treat whole fusions after, it in the weight part ratio of substrate and leaf of Turpinia pomifera (Roxb) D O. extract powder 4: 1 ratio, add the leaf of Turpinia pomifera (Roxb) D O. extract powder, stir, and keep under 65-95 ℃ the temperature to fusion, by in drilling pill device with 30-80 drip/minute speed, splash in the liquid Paraffin coolant, take out drop pill, drying.
Claims (4)
1, a kind of Turpinia pomifera(Roxb) D O. drop pill is characterized in that by leaf of Turpinia pomifera (Roxb) D O. extract powder and substrate, and by weight than being 1: 1-12 is formulated, described leaf of Turpinia pomifera (Roxb) D O. extract powder is formed by following prepared: get the water that leaf of Turpinia pomifera (Roxb) D O. is put into 8 times of its weight, decoct twice, each 1-2 hour, filter, filtrate is concentrated into the extractum shape, puts cold, adding ethanol makes the alcohol amount of containing reach 50-80%, leave standstill, the leaching supernatant reclaims ethanol, crushed after being dried or spray drying promptly make the leaf of Turpinia pomifera (Roxb) D O. extract powder; Described substrate can be stearic acid, gelatin, polyethylene glycol 6000, poloxamer 188 any materials, also can be several or whole mixture between them.
2, Turpinia pomifera(Roxb) D O. drop pill according to claim 1, the weight part ratio that it is characterized in that leaf of Turpinia pomifera (Roxb) D O. extract powder and substrate is 1: 2-6.
3, Turpinia pomifera(Roxb) D O. drop pill according to claim 1, the weight part ratio that it is characterized in that leaf of Turpinia pomifera (Roxb) D O. extract powder and substrate is 1: 4.
4, a kind of preparation technology who is used for claim 1,2,3 arbitrary described Turpinia pomifera(Roxb) D O. drop pill is as follows: with substrate be heated to 80-100 ℃ treat whole fusions after, add the leaf of Turpinia pomifera (Roxb) D O. extract powder again, be stirred to fusion, transfer in the drilling pill device and remain on 60-100 ℃ temperature, splash into 5-20 ℃ of liquid Paraffin, vegetable oil, in methyl-silicone oil, the arbitrary coolant of water, drain promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031292070A CN1552397A (en) | 2003-06-08 | 2003-06-08 | Shanxiangyuan drops and their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031292070A CN1552397A (en) | 2003-06-08 | 2003-06-08 | Shanxiangyuan drops and their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1552397A true CN1552397A (en) | 2004-12-08 |
Family
ID=34322386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031292070A Pending CN1552397A (en) | 2003-06-08 | 2003-06-08 | Shanxiangyuan drops and their preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1552397A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727630A (en) * | 2012-06-29 | 2012-10-17 | 河南中医学院 | Plant extract dripping pill |
-
2003
- 2003-06-08 CN CNA031292070A patent/CN1552397A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727630A (en) * | 2012-06-29 | 2012-10-17 | 河南中医学院 | Plant extract dripping pill |
| CN102727630B (en) * | 2012-06-29 | 2013-06-12 | 河南中医学院 | Plant extract dripping pill |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| ASS | Succession or assignment of patent right |
Owner name: JIANGXI TIANSHIKANG TRADITIONAL CHINESE MEDICINE Free format text: FORMER OWNER: TIANSHIKANG SCIENCE + TECHNOLOGY DEVELOPMENT CO., LTD., JIANGXI PROV. Effective date: 20050701 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20050701 Address after: No. 21, Jianshe Road, Jiangxi, Yingtan Applicant after: Tianshikang Chinese Medicines Co., Ltd., Jiangxi Address before: No. 21, middle station, Yujiang County, Jiangxi Applicant before: Xiangxi Tianshikang Sci-Tech Development Co., Ltd. |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |