CN1483393A - Starch hollow capsule and production technslogy thereof - Google Patents
Starch hollow capsule and production technslogy thereof Download PDFInfo
- Publication number
- CN1483393A CN1483393A CNA021347506A CN02134750A CN1483393A CN 1483393 A CN1483393 A CN 1483393A CN A021347506 A CNA021347506 A CN A021347506A CN 02134750 A CN02134750 A CN 02134750A CN 1483393 A CN1483393 A CN 1483393A
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- starch
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Abstract
The present invention relates to a starch hollow capsule and its production process. It is mainly characterized by that said capsule is composed of (wt%) 25%-94.9% of plant starch or starch derivative, 0.1%-30% of plasticizer and 5%-20% of water through the processes of mixing starch or starch derivative and water, heating them to above 60 deg.C, stirring them uniformly, adding plasticizer, uniformly mixing them, heat-insulating, standing still, removing bubble and pouring the above-mentioned material into mold, drying so as to obtain the invented hollow capsule.
Description
Technical field
The present invention relates to a kind of medicinal hollow glue and assist and production technology, the hollow glue that does not especially contain animal proteinum is assisted, and comprises that ebonite is assisted with flexible glue to assist and production technology.
Background technology
At present, hollow glue is assisted and is comprised that it is gelatin that ebonite is assisted the main component of assisting with flexible glue, its production technology mainly is to utilize the skin from animal, the gelatin that bone extracts, and adds some plasticizers, edible pigment and opacifier and make gelatin solution, and the reuse mould is stained with glue, solidify, dry and form.This glue by manufacturing of gelatin assist behind the filling medicine owing to gelatin contain animal proteinum be subject to environmental change and in the composition influence of powder charge thing, defective such as existence easily becomes fragile, degeneration, disintegration exceed standard.In view of this, it is that primary raw material is made plant gum and assisted that people attempt again with water-soluble cellulose, overcome effectively because the hidden danger that animal proteinum exists, but its poor mobile performance, disintegration instability, and cost height is difficult to adapt to mechanization filling medicine.In sum, existing glue,medicinal is assisted owing to be subjected to raw-material the influence and the restriction of traditional handicraft, and its character remains the instability objectively, affects the shelf-life that it is deposited widely.
Summary of the invention
The objective of the invention is to disclose the hollow glue of a kind of starch and assist, this glue is assisted and is had stable in properties, thereby can prolong the shelf-life that stores, energy savings.
Another object of the present invention is to disclose the production technology that the hollow glue of above-mentioned starch is assisted, thereby reaches environment-friendly high-efficiency, and simple and direct easy control is convenient and practical.
Above-mentioned purpose of the present invention is to realize by such technical scheme, be that the hollow glue of starch of the present invention is assisted by components such as plant amylum or starch derivatives, plasticizer, water and formed, the percentage by weight of described plant amylum or starch derivatives, plasticizer, water is plant amylum or starch derivatives 25%-94.9%, plasticizer 0.1%-30%, water 5%-20%.
Moreover, as the production technology that the present invention taked, comprise the production technology that empty hard is assisted and flexible glue is assisted, wherein ebonite is assisted and is comprised that system liquid, mucus, oven dry, cutting, fit, flexible glue are assisted and comprise system liquid, be stained with liquid, cooling, suction mould, material filling, pressing, oven dry; The system liquid that described ebonite is assisted and flexible glue is assisted all is that starch or starch derivatives, water is mixed and be heated to more than 60 ℃ after by proportioning, evenly stirs, and then adds plasticizer by proportioning, and mix homogeneously, insulation is left standstill, and removes to pour the insulation hopper into behind the bubble and wait to be stained with.
The system liquid that described ebonite is assisted and flexible glue is assisted all is to be by mixed after 10.2-61.8% and the 35.3-88.2% proportioning and be heated to 65 ℃ with starch or starch derivatives, water, evenly stir, and then the proportioning of pressing 0.1-25.3% adds plasticizer, mix homogeneously, insulation is left standstill, and removes to pour the insulation hopper behind the bubble into and wait to be stained with.
The system liquid that described ebonite is assisted and flexible glue is assisted all is to be by mixed after 41.2% and 52.2% proportioning and be heated to 65 ℃ with starch or starch derivatives, water, evenly stir, and then add plasticizer, mix homogeneously by 6.6% proportioning, insulation is left standstill, and removes to pour the insulation hopper behind the bubble into and wait to be stained with.
Described plasticizer is a glycerol.
Adopt technique scheme, do not contain thereby amylan disclosed in this invention is assisted animal proteinum make its not changeableness, become fragile, disintegration is stable, prolongs greatly to store the shelf-life and reduce cost.Moreover the environmental pollution that can avoid the extraction because of animal proteinum to cause, be beneficial to the simple and direct easy control of environmental protection and technology.
The specific embodiment
Below in conjunction with embodiment the present invention is made further enumeration.
With 100g is example, takes by weighing starch or starch derivatives 10.2-61.8g,, be preferably 41.2g; Add entry 35.3-88.2g then, preferably 52.2g; And be heated to 65 ℃, evenly be stirred to and fully dissolve the back and add plasticizer glycerol 0.1-25.3g, be preferably 6.6g, mix homogeneously, insulation is left standstill, pour in the insulation hopper after removing bubble, again through be stained with liquid, dry, pull out shell, cutting, fit and make ebonite and assist.Or again through being stained with liquid, cooling, suction mould, material filling, pressing, oven dry and make flexible glue and assist.
Claims (6)
1, the hollow glue of a kind of starch is assisted, it is characterized in that the hollow glue of described starch is assisted by components such as plant amylum or starch derivatives, plasticizer, water is formed, and the percentage by weight of described plant amylum or starch derivatives, plasticizer, water is plant amylum or starch derivatives 25%-94.9%, plasticizer 0.1%-30%, water 5%-20%.
2, the hollow glue of a kind of starch according to claim 1 is assisted, and it is characterized in that described plasticizer is a glycerol.
3, the hollow glue of a kind of starch production technology of assisting comprises the production technology that empty hard is assisted and flexible glue is assisted, and wherein ebonite is assisted and comprised that system liquid, mucus, oven dry, cutting, fit, flexible glue are assisted and comprise system liquid, be stained with liquid, cooling, suction mould, material filling, pressing, oven dry; It is characterized in that described ebonite is assisted and flexible glue is assisted system liquid all is that starch or starch derivatives, water is mixed and be heated to more than 60 ℃ after by proportioning, evenly stir, and then add plasticizer, mix homogeneously by proportioning, insulation is left standstill, and removes to pour the insulation hopper behind the bubble into and wait to be stained with.
4, the hollow glue of a kind of starch according to claim 2 production technology of assisting, it is characterized in that described ebonite is assisted and flexible glue is assisted system liquid all is is by mixed after 10.2-61.8% and the 35.3-88.2% proportioning and be heated to 65 ℃ with starch or starch derivatives, water, evenly stir, and then the proportioning of pressing 0.1-25.3% adds plasticizer, mix homogeneously, insulation is left standstill, and removes to pour the insulation hopper behind the bubble into and wait to be stained with.
5, the hollow glue of a kind of starch according to claim 3 production technology of assisting, it is characterized in that described ebonite is assisted and flexible glue is assisted system liquid all is is by mixed after 41.2% and 52.2% proportioning and be heated to 65 ℃ with starch or starch derivatives, water, evenly stir, and then add plasticizer by 6.6% proportioning, mix homogeneously, insulation is left standstill, and removes to pour the insulation hopper behind the bubble into and wait to be stained with.
6, the production technology of assisting according to the hollow glue of any starch described in the claim 3-5 is characterised in that described plasticizer is a glycerol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNA021347506A CN1483393A (en) | 2002-09-17 | 2002-09-17 | Starch hollow capsule and production technslogy thereof |
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CNA021347506A CN1483393A (en) | 2002-09-17 | 2002-09-17 | Starch hollow capsule and production technslogy thereof |
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CN1483393A true CN1483393A (en) | 2004-03-24 |
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CNA021347506A Pending CN1483393A (en) | 2002-09-17 | 2002-09-17 | Starch hollow capsule and production technslogy thereof |
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Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1333006C (en) * | 2005-04-07 | 2007-08-22 | 天津大学 | Vegetable capsule of starch composition and preparation method |
CN100393296C (en) * | 2004-12-09 | 2008-06-11 | 浙江工业大学 | Formula of making hollow capsule and its preparation method |
WO2010020098A1 (en) * | 2008-08-18 | 2010-02-25 | 北京天衡药物研究院 | Gastric retention drug delivery system, preparation method and use thereof |
CN101817938A (en) * | 2010-03-18 | 2010-09-01 | 上海心尔新材料科技股份有限公司 | Transparent starch-packaging material and production method thereof |
CN101708174B (en) * | 2009-12-11 | 2011-04-13 | 梁贤昌 | Plant hollow capsule, soft capsule composition and preparation methods thereof |
CN101693020B (en) * | 2009-10-22 | 2011-04-20 | 华慧颖 | Enteric soluble medicine empty capsule prepared by replacing part of gelatin with defatted soybean meal extractive and preparation process |
CN102525995A (en) * | 2011-12-23 | 2012-07-04 | 湖北人福康华药用辅料有限公司 | Plant officinal hollow capsule and preparation method thereof |
CN104324381A (en) * | 2014-09-29 | 2015-02-04 | 湖南尔康制药股份有限公司 | Starch capsule having moisturizing capability and preparation method thereof |
EP2865374A1 (en) | 2013-10-26 | 2015-04-29 | Zhongshan Capsule Starch Material Technology Co., Ltd. | Mixing and extruding method for preparing starch softgel capsules |
CN104688711A (en) * | 2015-03-09 | 2015-06-10 | 湖南尔康制药股份有限公司 | Hollow plant capsule and preparation method thereof |
EP2937081A1 (en) | 2014-04-21 | 2015-10-28 | Hunan Er-Kang Pharmaceutical Co., Ltd. | Hydroxypropyl starch vacant capsules and a process for producing them |
CN105475942A (en) * | 2015-12-18 | 2016-04-13 | 湖南尔康制药股份有限公司 | Freeze-dried bee product capsule |
CN105709234A (en) * | 2016-01-29 | 2016-06-29 | 中国药科大学 | Oxidized hydroxypropyl starch empty capsules and preparation process thereof |
CN104666275B (en) * | 2015-03-09 | 2017-04-26 | 湖南尔康制药股份有限公司 | Starch-based plant empty capsule |
-
2002
- 2002-09-17 CN CNA021347506A patent/CN1483393A/en active Pending
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100393296C (en) * | 2004-12-09 | 2008-06-11 | 浙江工业大学 | Formula of making hollow capsule and its preparation method |
CN1333006C (en) * | 2005-04-07 | 2007-08-22 | 天津大学 | Vegetable capsule of starch composition and preparation method |
WO2010020098A1 (en) * | 2008-08-18 | 2010-02-25 | 北京天衡药物研究院 | Gastric retention drug delivery system, preparation method and use thereof |
CN101693020B (en) * | 2009-10-22 | 2011-04-20 | 华慧颖 | Enteric soluble medicine empty capsule prepared by replacing part of gelatin with defatted soybean meal extractive and preparation process |
CN101708174B (en) * | 2009-12-11 | 2011-04-13 | 梁贤昌 | Plant hollow capsule, soft capsule composition and preparation methods thereof |
CN101817938B (en) * | 2010-03-18 | 2013-01-09 | 上海心尔新材料科技股份有限公司 | Transparent starch-packaging material and production method thereof |
CN101817938A (en) * | 2010-03-18 | 2010-09-01 | 上海心尔新材料科技股份有限公司 | Transparent starch-packaging material and production method thereof |
CN102525995B (en) * | 2011-12-23 | 2013-10-30 | 湖北人福康华药用辅料有限公司 | Plant officinal hollow capsule and preparation method thereof |
CN102525995A (en) * | 2011-12-23 | 2012-07-04 | 湖北人福康华药用辅料有限公司 | Plant officinal hollow capsule and preparation method thereof |
EP2865374A1 (en) | 2013-10-26 | 2015-04-29 | Zhongshan Capsule Starch Material Technology Co., Ltd. | Mixing and extruding method for preparing starch softgel capsules |
EP2937081A1 (en) | 2014-04-21 | 2015-10-28 | Hunan Er-Kang Pharmaceutical Co., Ltd. | Hydroxypropyl starch vacant capsules and a process for producing them |
US9693964B2 (en) | 2014-04-21 | 2017-07-04 | Hunan Er-Kang Pharmaceutical Co., Ltd. | Hydroxypropyl starch vacant capsules and a process for producing them |
CN104324381A (en) * | 2014-09-29 | 2015-02-04 | 湖南尔康制药股份有限公司 | Starch capsule having moisturizing capability and preparation method thereof |
CN104324381B (en) * | 2014-09-29 | 2017-01-18 | 湖南尔康制药股份有限公司 | Starch capsule having moisturizing capability and preparation method thereof |
CN104688711A (en) * | 2015-03-09 | 2015-06-10 | 湖南尔康制药股份有限公司 | Hollow plant capsule and preparation method thereof |
CN104666275B (en) * | 2015-03-09 | 2017-04-26 | 湖南尔康制药股份有限公司 | Starch-based plant empty capsule |
CN104688711B (en) * | 2015-03-09 | 2017-08-29 | 湖南尔康制药股份有限公司 | A kind of phyteral Capsules and preparation method thereof |
CN105475942A (en) * | 2015-12-18 | 2016-04-13 | 湖南尔康制药股份有限公司 | Freeze-dried bee product capsule |
CN105709234A (en) * | 2016-01-29 | 2016-06-29 | 中国药科大学 | Oxidized hydroxypropyl starch empty capsules and preparation process thereof |
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