CN1299283A - 包含l－肉毒碱或烷酰基l－肉毒碱和nadh和/或nadph的组合物 - Google Patents
包含l－肉毒碱或烷酰基l－肉毒碱和nadh和/或nadph的组合物 Download PDFInfo
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- CN1299283A CN1299283A CN99805644A CN99805644A CN1299283A CN 1299283 A CN1299283 A CN 1299283A CN 99805644 A CN99805644 A CN 99805644A CN 99805644 A CN99805644 A CN 99805644A CN 1299283 A CN1299283 A CN 1299283A
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- Prior art keywords
- carnitine
- nadh
- compositions
- alkanoyl
- acid
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- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 title claims abstract description 86
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 title claims abstract description 70
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title claims abstract description 64
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- -1 alkanoyl L-carnitine Chemical compound 0.000 title claims abstract description 16
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
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Applications Claiming Priority (2)
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| ITRM98A000238 | 1998-04-17 | ||
| IT98RM000238A IT1299161B1 (it) | 1998-04-17 | 1998-04-17 | Composizione comprendente l-carnitina o un'alcanoil l-carnitina e nadh e/o nadph |
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|---|---|
| CN1299283A true CN1299283A (zh) | 2001-06-13 |
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| CN99805644A Pending CN1299283A (zh) | 1998-04-17 | 1999-04-14 | 包含l－肉毒碱或烷酰基l－肉毒碱和nadh和/或nadph的组合物 |
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| EP (1) | EP1071424A1 (is) |
| JP (1) | JP2002512191A (is) |
| KR (1) | KR20010042765A (is) |
| CN (1) | CN1299283A (is) |
| AU (1) | AU750645B2 (is) |
| BR (1) | BR9909712A (is) |
| CA (1) | CA2328331A1 (is) |
| EE (1) | EE200000601A (is) |
| HU (1) | HUP0101914A3 (is) |
| IL (1) | IL139014A0 (is) |
| IS (1) | IS5663A (is) |
| IT (1) | IT1299161B1 (is) |
| NO (1) | NO20005128L (is) |
| PL (1) | PL343482A1 (is) |
| SK (1) | SK15442000A3 (is) |
| TR (1) | TR200002894T2 (is) |
| WO (1) | WO1999053921A1 (is) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101677912A (zh) * | 2007-05-11 | 2010-03-24 | 希格马托制药工业公司 | 可用于递送化妆品活性成分的凝胶 |
| CN104306390A (zh) * | 2014-10-23 | 2015-01-28 | 苏州人本药业有限公司 | 还原型辅酶ⅱ的用途 |
| WO2016131320A1 (zh) * | 2015-02-17 | 2016-08-25 | 苏州人本药业有限公司 | Nadph在制备治疗心脏疾病药物中的应用 |
| CN109105702A (zh) * | 2018-08-30 | 2019-01-01 | 泓博元生命科技（深圳）有限公司 | 一种含有nadh的组合物、应用及能量补充剂的制备方法 |
| CN109170907A (zh) * | 2018-08-30 | 2019-01-11 | 泓博元生命科技（深圳）有限公司 | 一种含有nmn的组合物、应用及运动饮料的制备方法 |
| CN109496154A (zh) * | 2017-12-22 | 2019-03-19 | 邦泰生物工程(深圳)有限公司 | 一种nadh复方组合物及其制剂和应用 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8252309B2 (en) | 2000-04-04 | 2012-08-28 | Sigma-Tau Industrie Farmaceutiche Riunite Spa | Dietary supplement energy-providing to skeletal muscles |
| DE10326822A1 (de) * | 2003-06-11 | 2005-01-05 | Herzpharma Vita-Check Diagnosegeräte GmbH | Mittel zur Nahrungsergänzung, dieses Mittel enthaltende pharmazeutische Präparate und Verwendungen des Mittels |
| WO2011022786A1 (en) * | 2009-08-31 | 2011-03-03 | Pharmaqest Pty Ltd | Methods for diagnosis and treatment of chronic fatigue syndrome |
| HRP20220040T1 (hr) | 2018-04-20 | 2022-04-15 | Pacotrade Ag | Uređaj za usitnjavanje duboko zamrznutih prehrambenih proizvoda pripremljenih u obliku blokova |
| CA3115743A1 (en) * | 2018-10-10 | 2020-04-16 | So Ngor Sally LEUNG | Health-care product composition for enriching asthenic disease, preparation method therefor and use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1054698A (is) * | 1964-12-04 | |||
| US5292538A (en) * | 1992-07-22 | 1994-03-08 | Metagenics, Inc. | Improved sustained energy and anabolic composition and method of making |
| DE4335454A1 (de) * | 1993-10-19 | 1995-04-20 | Schleicher Peter | Geriatrikum |
| JPH09110708A (ja) * | 1995-08-11 | 1997-04-28 | Taisho Pharmaceut Co Ltd | 滋養強壮用生薬配合製剤 |
| JPH0959161A (ja) * | 1995-08-23 | 1997-03-04 | Taisho Pharmaceut Co Ltd | 疲労改善用組成物 |
| IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
| IT1283951B1 (it) * | 1996-03-15 | 1998-05-07 | Mendes Srl | Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di |
| US5712259A (en) * | 1996-04-22 | 1998-01-27 | Birkmayer Pharmaceuticals | NADH and NADPH pharmaceuticals for treating chronic fatigue syndrome |
| US6077828A (en) * | 1996-04-25 | 2000-06-20 | Abbott Laboratories | Method for the prevention and treatment of cachexia and anorexia |
| JPH10175856A (ja) * | 1996-10-14 | 1998-06-30 | Taisho Pharmaceut Co Ltd | 疲労改善剤 |
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1998
- 1998-04-17 IT IT98RM000238A patent/IT1299161B1/it active IP Right Grant
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1999
- 1999-04-14 SK SK1544-2000A patent/SK15442000A3/sk unknown
- 1999-04-14 AU AU34428/99A patent/AU750645B2/en not_active Ceased
- 1999-04-14 KR KR1020007011499A patent/KR20010042765A/ko not_active Application Discontinuation
- 1999-04-14 TR TR2000/02894T patent/TR200002894T2/xx unknown
- 1999-04-14 BR BR9909712-5A patent/BR9909712A/pt not_active IP Right Cessation
- 1999-04-14 CN CN99805644A patent/CN1299283A/zh active Pending
- 1999-04-14 CA CA002328331A patent/CA2328331A1/en not_active Abandoned
- 1999-04-14 EP EP99916039A patent/EP1071424A1/en not_active Withdrawn
- 1999-04-14 IL IL13901499A patent/IL139014A0/xx unknown
- 1999-04-14 EE EEP200000601A patent/EE200000601A/xx unknown
- 1999-04-14 WO PCT/IT1999/000088 patent/WO1999053921A1/en not_active Application Discontinuation
- 1999-04-14 HU HU0101914A patent/HUP0101914A3/hu unknown
- 1999-04-14 PL PL99343482A patent/PL343482A1/xx not_active Application Discontinuation
- 1999-04-14 JP JP2000544325A patent/JP2002512191A/ja active Pending
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2000
- 2000-10-12 NO NO20005128A patent/NO20005128L/no not_active Application Discontinuation
- 2000-10-13 IS IS5663A patent/IS5663A/is unknown
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101677912A (zh) * | 2007-05-11 | 2010-03-24 | 希格马托制药工业公司 | 可用于递送化妆品活性成分的凝胶 |
| CN104306390A (zh) * | 2014-10-23 | 2015-01-28 | 苏州人本药业有限公司 | 还原型辅酶ⅱ的用途 |
| WO2016062125A1 (zh) * | 2014-10-23 | 2016-04-28 | 苏州人本药业有限公司 | 还原型辅酶ⅱ的用途 |
| WO2016131320A1 (zh) * | 2015-02-17 | 2016-08-25 | 苏州人本药业有限公司 | Nadph在制备治疗心脏疾病药物中的应用 |
| CN109496154A (zh) * | 2017-12-22 | 2019-03-19 | 邦泰生物工程(深圳)有限公司 | 一种nadh复方组合物及其制剂和应用 |
| WO2019119445A1 (zh) * | 2017-12-22 | 2019-06-27 | 邦泰生物工程(深圳)有限公司 | 一种nadh复方组合物及其制剂和应用 |
| US10894059B2 (en) | 2017-12-22 | 2021-01-19 | Bontac Bio-Engineering (Shenzhen) Co., Ltd | NADH compound composition, and preparation and use thereof |
| CN109496154B (zh) * | 2017-12-22 | 2021-07-06 | 邦泰生物工程(深圳)有限公司 | 一种nadh复方组合物及其制剂和应用 |
| CN109105702A (zh) * | 2018-08-30 | 2019-01-01 | 泓博元生命科技（深圳）有限公司 | 一种含有nadh的组合物、应用及能量补充剂的制备方法 |
| CN109170907A (zh) * | 2018-08-30 | 2019-01-11 | 泓博元生命科技（深圳）有限公司 | 一种含有nmn的组合物、应用及运动饮料的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| PL343482A1 (en) | 2001-08-27 |
| JP2002512191A (ja) | 2002-04-23 |
| ITRM980238A1 (it) | 1999-10-17 |
| BR9909712A (pt) | 2000-12-26 |
| EP1071424A1 (en) | 2001-01-31 |
| EE200000601A (et) | 2002-04-15 |
| NO20005128D0 (no) | 2000-10-12 |
| AU3442899A (en) | 1999-11-08 |
| WO1999053921A1 (en) | 1999-10-28 |
| KR20010042765A (ko) | 2001-05-25 |
| CA2328331A1 (en) | 1999-10-28 |
| AU750645B2 (en) | 2002-07-25 |
| SK15442000A3 (sk) | 2001-06-11 |
| HUP0101914A3 (en) | 2002-12-28 |
| NO20005128L (no) | 2000-12-18 |
| IL139014A0 (en) | 2001-11-25 |
| TR200002894T2 (tr) | 2001-01-22 |
| IT1299161B1 (it) | 2000-02-29 |
| HUP0101914A2 (hu) | 2002-03-28 |
| IS5663A (is) | 2000-10-13 |
| ITRM980238A0 (it) | 1998-04-17 |
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